2017 Fiscal Year Final Research Report
Regeneration of circumferential esophagus with peristalsis and enough length for clinical use, in canine experiments
| Project/Area Number |
15K10119
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Digestive surgery
|
|---|
| Research Institution | Doshisha University |
|---|
Principal Investigator |
HAGIWARA Akeo 同志社大学, 生命医科学部, 教授 (90198648)
|
|---|
| Research Collaborator |
TORII Hiroko
OZAMOTO Yuki
TSUJIMOTO Hiroyuki
|
|---|
| Project Period (FY) |
2015-04-01 – 2018-03-31
|
| Keywords | 消化管再生 / 動物実験 / 再生医学 |
|---|
| Outline of Final Research Achievements |
Transplantation of mucosal epithelial tissues of the digestive canal is difficult. In the present research hepatic cells were used instead of the epithelial cells of the mucosal cells. The scaffolds where liver cells were disseminated were rolled with the greater omentum into a shape of tube, and then the tube was incubated in the peritoneal cavity of the animal. Microscopically it was confirmed that the blood vessels infiltrated into the scaffolds from the omentum and the liver cells grew successfully in the layers of the scaffolds.
|
| Free Research Field |
消化器外科学、再生医学
|
