Development of new respiratory management method for airway surgery using Apneic Oxygenation.

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K10261
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Respiratory surgery
• Research Institution: Kagawa University
• Principal Investigator: TETSUHIKO GO 香川大学, 医学部附属病院, 講師 (50313656)
• Co-Investigator(Kenkyū-buntansha): 松浦 奈都美 香川大学, 医学部附属病院, 助教 (20572853) ; 藤原 敦史 香川大学, 医学部附属病院, 病院助教 (00748642) ; 横見瀬 裕保 香川大学, 医学部, 教授 (80231728)
• Project Period (FY): 2015-10-21 – 2018-03-31
• Keywords: 気管手術 / Apneic oxygenation

Outline of Final Research Achievements

Apneic oxygenation is a ventilation method in the open-airway phase of tracheal surgery. This method provides adequate oxygenation, but has the disadvantage of causing progressive hypercapnia. In order to repress hypercapnia, we developed a Y-shaped catheter that can be located in the tips of both bronchi. We conducted experimental study with a canine tracheal resection and reconstruction surgery model to evaluate the efficacy of a Y-shaped catheter. Ventilation during open airway phase was maintained with small catheter as apneic oxygenation for 30 minutes until the end of tracheal reconstruction. Apneic oxygenation using a Y-shaped catheter significantly repressed the accumulation of carbon dioxide compared with the straight catheter. This result showed the possibility of clinical application of Y-shaped catheter.

Free Research Field

呼吸器外科