Factors related to QOL of patients with bone metastases.

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K10388
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Orthopaedic surgery
• Research Institution: The University of Tokyo
• Principal Investigator: SHINODA YUSUKE 東京大学, 医学部附属病院, 講師 (80456110)
• Co-Investigator(Kenkyū-buntansha): 松平 浩 東京大学, 医学部附属病院, その他 (10302697) ; 澤田 良子 東京大学, 医学部附属病院, 病院診療医 (30648308) ; 岩瀬 哲 埼玉医科大学, 医学部附属病院, 教授 (60372372) ; 芳賀 信彦 東京大学, 医学部附属病院, 教授 (80251263)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 転移性骨腫瘍 / リハビリテーション / 緩和ケア / ADL / QOL

Outline of Final Research Achievements

Questionnaires (EQ-5D, NRS(Numerical Rating Scale) for pain, EORTC QLQ-PAL15 and BM22, generic screening tool, K6) were self-completed by 64 patients with bone metastasis recruited from April 2015 to June 2016 in our hospital. Of the 64 patients, 31 were male and 33 were female. Average age was 63.7. The average EQ-5D score was 0.58+-0.24. NRS, Physical Functioning (PAL15), Functional Interference (BM22), Emotional Functioning (PAL15), generic screening tool, K6, and PS (Performance Status) were co-related to EQ-5D by p<0.001. Psychosocial Aspects (BM22), SRE, previous chemotherapy, serum Ca corrected by Alb, and CRP were co-related to EQ-5D by p<0.05.
In conclusion, pain, physical function, and psychological factors seem to have strong effects on QOL of patients with bone metastasis. Consultation to physiatrists, orthopaedic surgeons, and clinical pshychotherapist might be important for improving the QOL of these patients.

Free Research Field

転移性骨腫瘍