2017 Fiscal Year Final Research Report
Study on the sedation/analgesia indicators and their regulation
| Project/Area Number |
15K10537
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Anesthesiology
|
|---|
| Research Institution | Kagawa University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2015-04-01 – 2018-03-31
|
| Keywords | 鎮静度 / 鎮痛度 / 筋弛緩度 / 自動制御 / 麻酔薬 / 区域麻酔 / 麻酔後回復 / 周術期管理 |
|---|
| Outline of Final Research Achievements |
We performed clinical investigations concerning the effect of regional anesthesia on post-anesthesia recovery, and sedation/analgesia level as a control target for the development of automatic anesthesia-related drug infusion system. We founded several advantages of femoral nerve block with cocktail periarticular injection, paravertebral block and fascia iliaca block supra-inguinal approach. We examined auditory evoked response value (aepEX) as a sedation index, combination of analgesia/nociception index based on heart rate variability, surgical pleth index on electroencephalogram and entropy difference on electromyogram as an analgesia index, and TOFcuff level as a muscle relaxation index, and showed that they can be applicable for the automatic control system.
|
| Free Research Field |
麻酔科学
|
