Establishment of bone quality improvement therapy using intelligent artificial bone

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K11160
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Prosthodontics/ Dental materials science and
• Research Institution: Hiroshima University
• Principal Investigator: DOI KAZUYA 広島大学, 医歯薬保健学研究科(歯), 助教 (80444686)
• Co-Investigator(Kenkyū-buntansha): 岡崎 洋平 広島大学, 病院(歯), 助教 (00706898) ; 日浅 恭 広島大学, 病院(歯), 講師 (60304432)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: PTH / 骨粗鬆症 / 骨質

Outline of Final Research Achievements

In this study, bone quality improvement therapy using combination methods of intelligent arterial bone: polyphosphate integrated porous HA and intermittent PTH administration was assessment under conditions of reduced bone quality and metabolism. The combination methods indicated the promotion of osteoblast activation, enhancement bone formation and establishment implant stability: preferable primary stability and achievement osseointegration in rabbit osteoporosis model.

Free Research Field

歯科補綴学