Establishment of saliva marker for screening gingivitis.

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K11415
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Social dentistry
• Research Institution: Okayama University
• Principal Investigator: Takeuchi Mayu 岡山大学, 大学病院, 助教 (90745382)
• Co-Investigator(Kenkyū-buntansha): 森田 学 岡山大学, 医歯薬学総合研究科, 教授 (40157904) ; 江國 大輔 岡山大学, 医歯薬学総合研究科, 准教授 (70346443) ; 友藤 孝明 朝日大学, 歯学部, 教授 (80335629) ; 水谷 慎介 岡山大学, 医歯薬学総合研究科, 助教 (90643312)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 歯肉炎 / スクリーニング / 唾液LDH / 口腔細菌叢 / 次世代シーケンサー

Outline of Final Research Achievements

We investigated the usefulness of non-invasive screening for gingivitis using saliva. Among university students, we investigated the association between gingivitis and lactate dehydrogenase level in saliva in a cross-sectional study and the association between oral microflora in saliva and progression of gingivitis in a longitudinal study. The level of lactate dehydrogenase in saliva was significantly associated with gingivitis. However, there was no significant association between oral microflora and progression of gingivitis in university students.

Free Research Field

口腔衛生学