Pathology findings and the establishment of prevention method for the deposits on the pharyngeal mucosal surface of persons requiring nursing care with dry mouth.

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K11436
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Social dentistry
• Research Institution: Matsumoto Dental University
• Principal Investigator: OGASAWARA TADASHI 松本歯科大学, 歯学部, 教授 (10167314)
• Co-Investigator(Kenkyū-buntansha): 柿木 保明 九州歯科大学, 歯学部, 教授 (10420762) ; 藤井 航 九州歯科大学, 歯学部, 准教授 (50387700) ; 落合 隆永 松本歯科大学, 歯学部, 講師 (20410417) ; 長谷川 博雅 松本歯科大学, 総合歯科医学研究所, 教授 (60164828)
• Research Collaborator: MIYAHARA Kota ; ISHIHARA Noriaki ; ASAHINA Noriaki ; HIGUCHI Yudai ; SHINOTSUKA Koichi ; IWASAKI Hitoshi
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 経管栄養 / 咽頭の付着物 / 剥離上皮膜 / 口腔乾燥 / 歯科 / 寝膜ケア

Outline of Final Research Achievements

Pharyngeal deposits were denatured stratified squamous epithelium positive for HE staining, and all mucus was positive for MUC 7 staining.　 It was suggested that pharyngeal deposits were derived from the oral mucosa. The deposits on the pharyngeal mucosal surface was associated with the presence of membranous substances on the oral mucosa of the patients with tube feeding.　It was suggested that the prevention of formation of membranous substances on oral mucosa prevents the formation of pharyngeal deposits.It was suggested that pharyngeal deposits did not affect the bacteria causing pneumonia.After moisturizing the oral mucosa, the formation rate of membranous substances on oral mucosa was 56.3%, and the deposits on the pharyngeal mucosal surface was 6.3%.The patients without the membranous substances on oral mucosa didn’t find the deposits on the pharyngeal mucosal surface. It was suggested that the oral mucosa care would prevent the deposits on the pharyngeal mucosal surface.

Free Research Field

障害者歯科　高齢者歯科　有病者歯科