Effect of exercise on food allergy in mice.

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K12731
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Childhood science (childhood environment science)
• Research Institution: Kurashiki University of Science and the Arts
• Principal Investigator: Shiiba Daisuke 倉敷芸術科学大学, 生命科学部, 講師 (20515233)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: アナフィラキシー / 運動

Outline of Final Research Achievements

In this study, it was determine the effect of chronic aerobic exercise on chicken egg ovalbumin (OVA) - induced anaphylaxis in BALB/c and C57BL/6J mice. In the results, In time-course of the change of rectal temperature, the decreases in rectal temperature, that is anaphylactic symptoms in mice, by OVA injection were significantly prevented in EX mice compered with SED mice. In addition, elevation of hematocrit value were tendency to prevent in EX mice compered with SED mice. There results suggested that that is chronic voluntary aerobic exercise prevents OVA-induced anaphylaxis in mice. These findings might indicate that chronic aerobic exercise has potential approaches of preventing a food allergy and anaphylaxis.

Free Research Field

運動免疫学