2016 Fiscal Year Final Research Report
Challenge towards single-cell MS imaging
| Project/Area Number |
15K12762
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Chemical biology
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| Research Institution | National Institute of Advanced Industrial Science and Technology |
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Principal Investigator |
Takahashi Katsutoshi 国立研究開発法人産業技術総合研究所, 創薬基盤研究部門, 主任研究員 (00271792)
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Keywords | 質量イメージング / 単一細胞分析 / MALDI / FTICR-MS |
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| Outline of Final Research Achievements |
The laser focus optics of current in-house built MALDI-FTICRMS was improved so as to decrease the laser focus spot size onto the specimen to less than 5 micron from 10 micron.
The laser optics was also modified to enable the on-axis irradiation of different wavelength laser light with precisly controlled different timing to burn through-hole on the non-conductive thick sample specimen to prevent charging-up on the sample specimen during MS imaing measurement.
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| Free Research Field |
質量分析学
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