Developments of plasmic nanoparticle assemblies that are applicable for immunoassay

2016 Fiscal Year Final Research Report

• Project/Area Number: 15K13729
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Analytical chemistry
• Research Institution: Kagoshima University
• Principal Investigator: Niidome Yasuro 鹿児島大学, 理工学域理学系, 教授 (50264081)
• Project Period (FY): 2015-04-01 – 2017-03-31
• Keywords: 金ナノロッド / コアシェルナノロッド / ２量体 / プラズモン

Outline of Final Research Achievements

Dimers of gold nanorods were prepared. After careful optimizations, we have found the efficient and reproducible experimental condition to give the nanorod dimers. TEM observation showed that the yield of the nanorod dimers was about 50 %. The nanorod dimers were fractionized by density gradient centrifugation. A stepwise density gradient using sucrose was successful to fractionize the nanorod dimers. The resultant solution contained about 70% of nanorod dimers.
To make various surface modification on gold-silver core-shell nanorods, we have developed a surface modification to disperse the nanorod in polar organic solvents that ware acetonitrile, dimethylsulfoxide, and dimethylformamide. The surface modification contributed the colloidal dispersion of the core-shell nanorods on which functional peptides adsorbed.

Free Research Field

コロイド・界面化学