2016 Fiscal Year Final Research Report
Simultaneous crystallization and inclusion complexation of metal-organic framework with ganma-cyclodextrin
Project/Area Number |
15K14217
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Reaction engineering/Process system
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Research Institution | Sojo University |
Principal Investigator |
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Project Period (FY) |
2015-04-01 – 2017-03-31
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Keywords | 多孔質材料 / 有機結晶 / シクロデキストリン / 吸着 / 芳香族カルボン酸 / ドラッグキャリア / 両親媒性ナノ孔 / 金属有機構造体 |
Outline of Final Research Achievements |
Inner space of cyclodextrin (CD) can include organic compounds due to its hydrophobic nature. Metal-organic framework (CD-MOF) consisting of ganma-CD and KOH was formed by the methanol diffusion method. In addition, CD-MOF is expected to be used as a drug carrier for its biocompatibility. The purpose of this study was to investigate the simultaneous crystallization and inclusion complexation of CD-MOF with ferulic acid. Adsorption behaviors of aromatic carboxylic acids on the CD-MOF were also examined. In the hydrophilic and hydrophobic nanopore of CD-MOF, aromatic carboxylic acids were found to adsorb on the hydrophobic nanopore and be in isolation.
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Free Research Field |
反応工学
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