Dynamic three-dimensional cell patterning toward organ-on-a-chip

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K14232
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Biofunction/Bioprocess
• Research Institution: Shinshu University
• Principal Investigator: Akiyama Yoshitake 信州大学, 学術研究院繊維学系, 准教授 (80585878)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 細胞パターニング / マイクロ流体デバイス / 組織工学 / 磁気アルキメデス効果

Outline of Final Research Achievements

As an experimental-animal substitution method, micro-tissue construction in microfluidic devices (Organ-on-a-chip) has been attracted much more attention. Achievement of Organ-on-a-chip requires to development a manipulation method for cells and micro-tissues in the microchannel. In this study, the label-free magnetic assembly method that the author proposed was assessed. We demonstrated label-free cell patterning using a magnet array and label-free magnetic manipulation of micro-tissues using an electromagnetic device.

Free Research Field

ナノマイクロシステム