2017 Fiscal Year Final Research Report
Evaluation of a novel food function mechanism by the interspecies exosome crosstalk
| Project/Area Number |
15K14736
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Food science
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| Research Institution | University of Miyazaki |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | ナノ粒子 / 抗炎症作用 / 種間相互作用 |
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| Outline of Final Research Achievements |
We have established the method for the preparation of nano-particle derived from fruits and vegetables. This particle consists of diverse lipids and proteins, and RNA and flavonoids were occurred in Allium cepa derived one. This particle suppressed inflammatory response in macrophage and flavonoids were not responsible for this effect. Heat treatment of this particle did not affect on the anti-inflammatory effect of particle. Three subfractions were recovered from Curcuma longa derived nano-particle and all of them were incorporated into the macrophages and showed anti-inflammatory effects.
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| Free Research Field |
食品機能化学
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