2017 Fiscal Year Final Research Report
Elucidation of a novel mechanism for maintenance of multipotency in adult multipotent stem cells
Project/Area Number |
15K15059
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
General medical chemistry
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Research Institution | Akita University (2016-2017) Tohoku University (2015) |
Principal Investigator |
Akashi Hideo 秋田大学, 医学(系)研究科(研究院), 助教 (10431785)
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Project Period (FY) |
2015-04-01 – 2018-03-31
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Keywords | 成体幹細胞 / 分化誘導 / 神経細胞 / スプライシング |
Outline of Final Research Achievements |
Maintenance of Multipotency in adult stem cells is regulated by a mechanism different from that of embryonic stem cells. We identified a gene region involved in maintenance of multipotency and direction of differentiation. Furthermore, we indicated the genes induced neuron-specific expression and splicing. These results might lead to development of a novel method to produce neurons from adult stem cells.
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Free Research Field |
遺伝子工学
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