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2016 Fiscal Year Final Research Report

Study of physiological and phatophysiological functions of mitochondria supercomplex

Research Project

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Project/Area Number 15K15073
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field General medical chemistry
Research InstitutionSaitama Medical University

Principal Investigator

IKEDA Kazuhiro  埼玉医科大学, 医学部, 講師 (30343461)

Co-Investigator(Renkei-kenkyūsha) HORIE Kuniko (INOUE Kuniko)  埼玉医科大学, 医学部, 教授 (90261982)
INOUE Satoshi  埼玉医科大学, 医学部, 客員教授 (40251251)
Project Period (FY) 2015-04-01 – 2017-03-31
Keywordsミトコンドリア / 呼吸鎖 / 超複合体
Outline of Final Research Achievements

Mitochondrial respiration plays an important role in cells and its dysfunction is assumed to be involved in various diseases. We reported that COX7RP promotes the assembly of mitochondrial supercomplexes; however, the regulation and function of supercomplexes remains to be elucidated. In this study, expressional and functional analyses of COX7RP and other mitochondria-related factors were investigated in terms of cellar environment.

Free Research Field

分子生物学

URL: 

Published: 2018-03-22  

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