Inferring the cause of fever using NMR data obtained from serum and urine

2016 Fiscal Year Final Research Report

• Project/Area Number: 15K15271
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: General internal medicine(including psychosomatic medicine)
• Research Institution: Kyoto University
• Principal Investigator: Mori Tomoharu 京都大学, 医学研究科, 医員 (10725922)
• Project Period (FY): 2015-04-01 – 2017-03-31
• Keywords: 核磁気共鳴 / 発熱 / 敗血症 / パターン認識

Outline of Final Research Achievements

In this study serum and urine samples were collected in the emergency room from the patients whose chief complaint was fever. Firstly NMR data obtained from rat plasma samples were analyzed by our original signal processing method. The purpose of this study was to ascertain if any relation was detected between the results we acquired and the cause of fever. This pilot study revealed that our method was useful to sensitively find out the change in the property of serum. The NMR measurement and subsequent analysis of human serum samples are ready to start in the near future.

Free Research Field

救急医学