Optical imaging analysis of prediction error detection function in the posterior parietal cortex of mice.

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K16572
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Brain biometrics
• Research Institution: Niigata University
• Principal Investigator: Yoshitake Kohei 新潟大学, 脳研究所, 助教 (60649218)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 頭頂連合野 / 感覚連合 / 光学的機能イメージング / 細胞接着因子 / 予測誤差 / 視覚 / 体性感覚 / マウス

Outline of Final Research Achievements

We discovered that the posterior parietal cortex (PPC) of the visual system dorsal pathway responsible for spatial information processing responds to spatial discrepancies between visual information and whisker information. It was also found that it is necessary to normal experience both visual and whisker inputs in order to respond to this discrepancy in spatial information. This function was dependent on clustered protocadherin alpha, neuro-specific cell adhesion molecules. It was suggested that neural circuits dependent on molecular diversity of protocadherin are necessary for sensory integration.

Free Research Field

神経生理学