2017 Fiscal Year Final Research Report
Involvement of cortical neuron subtypes in the brain rhythms.
Project/Area Number |
15K18350
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Neurophysiology / General neuroscience
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Research Institution | Kyoto University |
Principal Investigator |
Ushimaru Mika 京都大学, 医学研究科, 特定研究員 (90604554)
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Keywords | 大脳皮質 / 徐波 |
Outline of Final Research Achievements |
Slow-wave oscillations, the predominant brain rhythm during sleep, are composed of Up/Down cycles. Depolarizing Up-states contain spindle and gamma components. But it is unknown how diverse subtypes of neurons affect to gamma/spindle waves. In this study, I recorded neural activity from cortical neuron subtypes (CCS, CPn and FS cells) from layer 5 and analyzed their relation to the gamma/spindle rhythms. I found that modulated cell ratio and firing phase in spindle/gamma oscillation were dependent on cell subtype and sublayer. These results suggest that firing activity of diverse neuron subtypes is highly associated with brain rhythms.
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Free Research Field |
神経科学
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