Comparison of insulin signaling pathway between broiler and layer type chicks

2016 Fiscal Year Final Research Report

• Project/Area Number: 15K18770
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Animal production science
• Research Institution: Kobe University
• Principal Investigator: Saneyasu Takaoki 神戸大学, 農学研究科, 助教 (20721236)
• Project Period (FY): 2015-04-01 – 2017-03-31
• Keywords: インスリン / 視床下部 / 骨格筋 / ブロイラー / レイヤー / Akt / FOXO / S6

Outline of Final Research Achievements

In this study, we compared regulatory mechanisms of insulin signaling pathway in hypothalamus and skeletal muscle between broiler and layer type chicks. The results in hypothalamus suggest that insulin signaling responds to the change of plasma insulin concentration in both types, and that there may be no difference in regulatory mechanisms of insulin signaling pathway between broiler and layer chicks. The results in skeletal muscle suggest that plasma insulin but not skeletal IGF-1 regulates insulin signaling pathway in response to feeding conditions in both types of chicks and showed that the levels of insulin signaling-related factors are higher in broiler than in layer type chicks.

Free Research Field

家畜生化学