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2016 Fiscal Year Final Research Report

Search for antimicrobial natural products as leads of therapeutic agents for the treatment of ophthalmic infections

Research Project

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Project/Area Number 15K18885
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Natural medicines
Research InstitutionThe University of Tokushima

Principal Investigator

Tanaka Naonobu  徳島大学, 大学院生物資源産業学研究部, 准教授 (40455598)

Project Period (FY) 2015-04-01 – 2017-03-31
Keywords抗菌活性天然物質 / 植物 / 海洋生物
Outline of Final Research Achievements

Searching study for antimicrobial natural products were carried out to develop new leads of therapeutic agents for the treatment of ophthalmic infections. The study resulted in the isolation of new antimicrobial meroterpenes and acylphloroglucinols from Hypericaceous plants and new antimicrobial phenylcoumarins from a Calophyllaceous plant. Hypatulin A isolated from Hypericum patulum is a structurally interesting tricyclic meroterpene possessing antimicrobial activity.

Free Research Field

天然物化学

URL: 

Published: 2018-03-22  

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