2016 Fiscal Year Final Research Report
Role of GLP-1 receptor in volatile anesthetic-induced postconditioning in mice.
Project/Area Number |
15K20046
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Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Anesthesiology
|
Research Institution | The University of Tokushima |
Principal Investigator |
|
Project Period (FY) |
2015-04-01 – 2017-03-31
|
Keywords | 吸入麻酔薬 / イソフルラン / ポストコンディショニング / 心筋保護 / 虚血再灌流障害 / GLP-1 |
Outline of Final Research Achievements |
We confirmed volatile anesthetic-induced and GLP-1-induced cardiac postconditioning protects against ischemia-reperfusion injury in mice. Additionally, our results show that volatile anesthetic-induced cardiac postconditioning protection is dependent on GLP-1 activation.
|
Free Research Field |
麻酔科学
|