Regeneration of tracheal epithelium using induced pluripotent stem cells

2016 Fiscal Year Final Research Report

• Project/Area Number: 15K20216
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Otorhinolaryngology
• Research Institution: Fukushima Medical University
• Principal Investigator: Ikeda Masakazu 福島県立医科大学, 医学部, 助手 (40707486)
• Project Period (FY): 2015-04-01 – 2017-03-31
• Keywords: iPS細胞

Outline of Final Research Achievements

The purpose of this study is shortening of the epithelialization period of inner side of artificial materials in the reconstruction of the trachea defect using the artificial materials. It was demonstrated that tracheal epithelium derived from induced pluripotent stem cells could survive without a becoming a tumor in nude rats in vivo.
Because a tracheal epithelium derived from induced pluripotent stem cells implanted it to artificial materials and an attendant, the possibility that we could realize shortening of the epithelialization period was demonstrated.

Free Research Field

耳鼻咽喉科学