Establishment of new tooth transplantation method using cultured periodontal ligament cells and GBR method

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K20629
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Periodontology
• Research Institution: Tokyo Dental College
• Principal Investigator: SESHIMA FUMI 東京歯科大学, 歯学部, 講師 (40550017)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 歯牙移植 / 歯根膜

Outline of Final Research Achievements

Periodontal tissue collected from the extracted dental root showed attachment of periodontal ligament cells on the ivory plate.In transplanted teeth, ankyloosis was recognized.It is conceivable that a sufficient amount of periodontal ligament cells could not be obtained in the root of the transplanted tooth for the occurrence of ankylosis. In the previous report, it is reported that ankylosis occurs when there is a periodontal defect of 9
square millimeters or more, and the current situation is that sufficient existence of periodontal ligament tissue is not obtained and sufficient proliferation is obtained It is thought that it was not.From now on, we will investigate the effective use of growth factors to promote proliferation seeding and establishment of a sufficient amount of periodontal ligament cells for transplanted teeth.We will also study the functional use of transplanted teeth after cryopreservation.

Free Research Field

歯周病