2016 Fiscal Year Final Research Report
Screening of ECM-selective peptide for Small-diameter artificial blood vessels
Project/Area Number |
15K21070
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Biofunction/Bioprocess
Biomedical engineering/Biomaterial science and engineering
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Research Institution | Nagoya University |
Principal Investigator |
Kanie Kei 名古屋大学, 創薬科学研究科, 助教 (80636407)
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Research Collaborator |
KATO Ryuji 名古屋大学, 大学院創薬科学研究科, 准教授
EBARA Mitsuhiro 物質・材料研究機構, MANAナノシステム分野, MANA准主任研究者
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Project Period (FY) |
2015-04-01 – 2017-03-31
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Keywords | ペプチド / 人工血管 / バイオマテリアル / 内皮細胞 / 高分子材料 / コラーゲンIV / 間葉系幹細胞 / 骨再生 |
Outline of Final Research Achievements |
Aim of this study is obtaining short selective-peptides for enhancing the effect of artificial blood vessel. There are two detail aims, one is screening ECM-selective adhesion peptides, and another is screening endotherial cell(EC)-selective adhesion peptides. As a result, some Collagen IV-selective peptides and EC-selective peptides were successfully obtained in this two years. Additionally, combination of peptide and polymeric materials could control the EC-selectivity.
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Free Research Field |
生物化学工学
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