Molecular morphological study on the effect of low nutrition in fetal stage on the digestive tract after birth

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K21558
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Eating habits; Applied health science
• Research Institution: Nakamura Gakuen College
• Principal Investigator: KUMAGAI Nana 中村学園大学, 栄養科学部, 助教 (70552983)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 低栄養 / 妊娠 / 経産婦 / 胎児 / 新生児 / 乳児 / 消化管 / 分子形態学

Outline of Final Research Achievements

I observed Molecular morphologically using the digestive tract (small intestine and large intestine) of neonates born from Wistar female rats, which are proper pregnancy or pregnant under low nutrition at different times. Shorter villi were observed in the ileum of neonates born from pregnancy mothers under low nutrition (low nutritional group) than the neonates born from normal pregnancy mothers (control・normal group).
In the large intestine, proximal colon of the low nutritional group, there are some difference from the control group. In addition, differences were found depending on the timing of low nutrition during pregnancy, there are suggested that low nutrition during pregnancy effects the small intestine and large intestine of children after birth

Free Research Field

栄養形態学、解剖学、栄養学、栄養科学