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2005 Fiscal Year Final Research Report Summary

Establishment of follow-up care system of patients with developmental disabilities with electronic record card and prevention of brain damage

Research Project

Project/Area Number 16300185
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionInternational University of Health and Welfare Graduate School

Principal Investigator

TAKASHIMA Sachio  International University of Health and Welfare Graduate School, Professor, 大学院, 教授 (70038743)

Co-Investigator(Kenkyū-buntansha) SIBAHARA Tetsutaro  University of Fukushima, Department of System Engineering, Professor, 経済学部情報システム講座, 教授 (10108706)
MATSUISHI Toyojiro  Kurume University, School of Medicine, Department of Pediatrics, Professor, 医学部小児科, 教授 (60157237)
HIKINO Toshiharu  University of Kyushu, Department of Pediatrics, Lecturer, 医学部小児科, 助手 (50346780)
Project Period (FY) 2004 – 2005
Keywordscomputer system / cranial imaging / perinatal brain damage / care system / MRI / neonate / developmental disorder
Research Abstract

A.Establishment of computer system
1)XLM file was used for medical data preservation, considering International standard and Medical Makeup Language plan.
2)Expression of medical data :
Medical data was expressed by Web browser, and the imaginings such as MRI or CT expressed by using NIH Image-J.
3)Input of medical data :
Interface of the medical data collected from the hospitals was compiled by input form taken from web browser.
4)Portable media :
USB was selected to transport the medical data, and input additional data in each hospital.
5)Protection of privacy of each patient :
All data were expressed by using password (PW) and reliable method of ID.
B.Establishment of the data base and its application to patients with developmental motor and intellectual disabilities.
1)Protocol of the items of medical data included prenatal, perinatal and neonatal clinical histories, laboratory data such as imaginings, and clinical course including medical treatments.
2)The transportation of clinical informati … More ons was useful to develop clinical medicine of developmental disorders.
3)Clinical informations were reliable, clinical data were real, and these data were thought to be useful for clinical research. More simple input system is continued to be investigated.
4)Personal informations were carefully protected when the data were transported. In addition, this card has the characteristics that this is carried by patients or their family.
C.Research on the prevention of brain damages (references 1-9).
Cranial imaging and neuropathological researches were also performed with clinical and pathological materials. The pathogenesis of age-related epilepsy and sudden infant death syndrome was found to be closely related to the development of inhibitory channels such as GABA receptors or K channels.
The prevention of brain damages by this computerized card system is now progressing and we hope this system contributes to prevent brain damages and to develop care system for the children with developmental disabilities. Less

  • Research Products

    (16 results)

All 2006 2005 2004

All Journal Article (15 results) Book (1 results)

  • [Journal Article] Neuropathology of methylmalonic acidemia in a child2006

    • Author(s)
      高嶋 幸男
    • Journal Title

      Pediatr Neurol 34

      Pages: 156-159

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Cystachionine β-synthse is enriched in the brains of Down' s patients2005

    • Author(s)
      高嶋 幸男
    • Journal Title

      Biochem Biophys Res Commun 338

      Pages: 1547-1550

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Pathogeneisis and prevention of pontosubicular necrosis.2005

    • Author(s)
      高嶋 幸男
    • Journal Title

      Neuroembryology 3

      Pages: 42-46

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Early and late development of Notch 3 in human brains.2005

    • Author(s)
      高嶋 幸男
    • Journal Title

      Neuroembryology 3

      Pages: 13-18

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] SIDSの病因における脳病理からアプローチ2005

    • Author(s)
      高嶋 幸男
    • Journal Title

      日本SIDS学会誌 5

      Pages: 38-44

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Pathogenesis and prevention of pontosubicular necrosis.2005

    • Author(s)
      Takashima S, Ichinohe A, Itoh M
    • Journal Title

      Neuroembryology 3

      Pages: 42-46

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Expression of glutamate transporter subtypes during normal corticogenesis and type lissencephaly.2005

    • Author(s)
      Furuta A, Takashima S, Yokoo H, Rothstein JD, Wada K, Iwaki T
    • Journal Title

      Develop Brain Res 155

      Pages: 155-164

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Early and late development of Notch 3 in human brains.2005

    • Author(s)
      Ichinohe A, Takahashi K, Tabira T, Takashima S
    • Journal Title

      Neuroembryology 3

      Pages: 13-18

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Cystathionine β-synthase is enriched in the brains of Down7S patients.2005

    • Author(s)
      Ichinohe A, Kanaumi T, Takashima S, Enokido Y, Nagai Y, Kimura H
    • Journal Title

      Biochemical and Biophysical Research Communications 338

      Pages: 1547-1550

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Approach from neuropathology on pathogenesis of SIDS.2005

    • Author(s)
      Ozawa Y, Takashima S, Tada H
    • Journal Title

      Japan SIDS Research Journal (Japanese) 5

      Pages: 38-44

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] SIDS2005

    • Author(s)
      Ozawa Y, Takashima S
    • Journal Title

      Dictionary of respiration(Arita H edn)(Asakura Pub., Tokyo)

      Pages: 313-324

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] α 2-adrenergic ceptor subtype alterations in the brainstem in the sudden infant death syndrome.2004

    • Author(s)
      高嶋 幸男
    • Journal Title

      Pathophysiology 10

      Pages: 229-234

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] α2-adrenergic ceptor subtype alterations in the brainstem in the sudden infant death syndrome.2004

    • Author(s)
      Ozawa Y, Takashima S, Tada H
    • Journal Title

      Pathophysiology 10

      Pages: 229-234

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Developmental neurotransmitters pathology in SIDS.2004

    • Author(s)
      Takashima S
    • Journal Title

      Abstract of SIDS International Conference in Canada, Edmonton, July 3

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Pathogenesis, plasticity and prevention of perinatal hypoxic- ischemic brain damage.2004

    • Author(s)
      Takashima S
    • Journal Title

      Abstract of 8th Asian and Oceanian Congress of Child Neurology, New Delhi, Oct 8

    • Description
      「研究成果報告書概要(欧文)」より
  • [Book] 乳幼児突然死症候群(有田秀穂編 : 呼吸の事典)2005

    • Author(s)
      小沢愉理, 高嶋幸男
    • Total Pages
      313-324
    • Publisher
      朝倉書店
    • Description
      「研究成果報告書概要(和文)」より

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Published: 2007-12-13  

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