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2007 Fiscal Year Final Research Report Summary

Longevity and lifestyle

Research Project

Project/Area Number 16300220
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied health science
Research InstitutionGifu University

Principal Investigator

MORITA Hiroyuki  Gifu University, Graduate School of Medicine, Associate Professor (90252147)

Co-Investigator(Kenkyū-buntansha) ISHIZUKA Tatsuo  Gifu University, Graduate School of Medicine, Professor (20108070)
UNO Yoshihiro  Gifu University, Graduate School of Medicine, Associate Professor (70293553)
Project Period (FY) 2004 – 2007
Keywordssurvey of food / survey of exercise / adiponectin / metabolic syndrome / software for nutritional analysis / diet fiber / blood pressure monitorine / unsaturated fatty acids
Research Abstract

1. Invention of software for analysis of daily meal
We have invented software for analysis of nutrients in daily meal from photographs taken by a digital camera. Plenty of nutrients and energy are automatically calculated and summed up when a dish is painted over the photograph on the software.
2. Effect of a fiber-rich liquid diet to metabolic syndrome
We performed a randomized control study on an effect of diet fiber on metabolic syndrome. Twenty five patients with metabolic syndrome were divided randomly into two groups (an ordinary liquid group and fiber-rich liquid group) and had taken either of the liquid for six months. Endpoints were body weight, waist circumference, serum lipids, 75gOGTT, etc. We are analyzing the results.
3.Beneficial effects of a home health care system
We have prospectively investigated beneficial effects of a home health care system which is composed by an automatic sphygmomanometer and ECG with data telecommunication. The blood pressure in the user was lower than that in the non-user. No difference between the two groups was found in BMI, serum lipids and glucose tolerance.
4. Lifestyle between long-lived and short-lived areas
A cross-sectional study on lifestyle between long-lived and short-lived areas in Gifu Prefecture was performed by medical checkup, photographs of the food and questionnaires. In the long-lived area, blood pressure, ability of exercise, plasma adiponectin concentrations and intake of n-3/n-6 ratio of unsaturated fatty acids were higher than the short-lived one.

  • Research Products

    (32 results)

All 2008 2007 2006 2005 2004 Other

All Journal Article (20 results) (of which Peer Reviewed: 10 results) Presentation (12 results)

  • [Journal Article] DHEA-sulfate concentration in Men from a Japanese longevity district2008

    • Author(s)
      Matsumoto M, Ishizuka T, Morita H, Uno Y, et. al.
    • Journal Title

      Geriatr Gerontol Int (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Effect of fasting on PPARγ and AMPK activity in adipocytes2008

    • Author(s)
      Kajita K, Uno Y, Morita H, Ishizuka T, et. al.
    • Journal Title

      Diabetes Res Clin Pract (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Platelet aggregation in obese and diabetic subjects: association with leptin level2007

    • Author(s)
      Sugiyama C, Morita H, Uno Y, IshizukaT, et. al.
    • Journal Title

      Platelets 18

      Pages: 128-134

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Effect of dehydroepiandrosterone on insulin sensitivity in Otsuka Long-Evans Tokushima-fatty rats2007

    • Author(s)
      Ishizuka T, Morita H, Uno Y, et. al.
    • Journal Title

      Acta Diabetol 44

      Pages: 219-226

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Platelet aggregation in obese and diabetic subjects : association with leptin level2007

    • Author(s)
      Sugiyama, C, Morita, H, Uno, Y, Ishizuka, T, et. al.
    • Journal Title

      Platelets 18

      Pages: 128-134

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Effect of dehydroepi-androsterone on insulin sensitivity in Otsuka Long-Evans Tokushima-fatty rats2007

    • Author(s)
      Ishizuka, T, Morita, H, Uno, Y, et. al.
    • Journal Title

      Acta Diabetol 44

      Pages: 219-226

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Physiologic roles of 11β-hydroxydehydrogenase type 2 in kidney2006

    • Author(s)
      Isomura Y, Morita H, et. al.
    • Journal Title

      Metabolism 55

      Pages: 1352-1357

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Physiologic roles of 11B-hydroxydehydrogenase type 2 in kidney2006

    • Author(s)
      Isomura, Y, Morita, H, et. al.
    • Journal Title

      Metabolism 55

      Pages: 1352-1357

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Paraneoplastic neurologic syndrome and autoimmune Addison disease in a patient with thymoma2005

    • Author(s)
      Morita H, Ishizuka T, et. al.
    • Journal Title

      Am J Med Sci 329

      Pages: 48-51

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Correlation between left ventricular mass and urinary sodium excretion in specific genotype of CYP11B22005

    • Author(s)
      Isaji M, Morita H, et. al.
    • Journal Title

      J Hypertens 23

      Pages: 1149-1157

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Association of Lys173Arg polymorphism with CYP11B2 expression in normal adrenal glands and aldosterone-producing adenomas2005

    • Author(s)
      Tanahashi H, Morita H, et. al.
    • Journal Title

      J Clin Endocrinol Metab 90

      Pages: 6226-6231

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Paraneoplastic neurologic syndrome and autoimmune Addison disease in a patient with thymoma2005

    • Author(s)
      Morita, H, Ishizuka, T, et. al.
    • Journal Title

      Am J Med Sci 329

      Pages: 48-51

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Correlation between left ventricular mass and urinary sodium excretion in specific genotype of CYP11B22005

    • Author(s)
      Isaji, M, Morita, H, et. al.
    • Journal Title

      J Hypertens 23

      Pages: 1149-1157

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Association of Lys173Arg polymorphism with CYP11B2 expression in normal adrenal glands and aldosterone-producing adenomas2005

    • Author(s)
      Tanahashi, H, Morita, H, et. al.
    • Journal Title

      J Olin Endocrinol Metab 90

      Pages: 6226-6231

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Plasma cortisol and cortisone concentrations in normal subjects and patients with adrenocortical disorders2004

    • Author(s)
      Morita H, Ishizuka T, et. al.
    • Journal Title

      Metabolism 53

      Pages: 89-94

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Protein kinase C(PKC)β modulates rerine phaophorylation of insulin receptor substrate-1(IRS-1)-effect of overexpressin of PKCβ on insulin signal transduction2004

    • Author(s)
      Ishizuka T, Morita H, Uno Y, et. al.
    • Journal Title

      Endocr Res 30

      Pages: 287-299

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Plasma cortisol and cortisone concentrations in normal subjects and patients with adrenocortical disorders2004

    • Author(s)
      Morita, H, Ishizuka, T, et. al.
    • Journal Title

      Metabolism 53

      Pages: 89-94

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Protein kinase C (PKC) B modulates rerine phaophorylation of insulin receptor substrate-1 (IRS-1) -effect of overexpressin of PKCB on insulin signal transduction2004

    • Author(s)
      Ishizuka, T, Morita, H, Uno, Y, et. al.
    • Journal Title

      Endocr Res 30

      Pages: 287-299

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] DHEA-sulfates concentration in Men from a Japanese longevity district

    • Author(s)
      Matsumoto, M, Ishizuka, T, Morita, H, Uno, Y, et. al.
    • Journal Title

      Geriatr Gerontol Int (in press)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Effect of fasting on PPARy and AMPK activity in adipocytes

    • Author(s)
      Kajita, K, Uno, Y, Morita, H, Ishizuka, T, et. al.
    • Journal Title

      Diabetes Res Olin Pract (in press)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Association of longevity factors with blood pressure, ability of exercise or glucose tolerance?2006

    • Author(s)
      Ishizuka T, Matsumoto M, Morita H, Uno Y, et. al.
    • Organizer
      66th Scientific Sessions of American Diabetes Associations
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      20060609-13
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Association of longevity factors with blood pressure, ability of exercise or glucose tolerance2006

    • Author(s)
      Ishizuka, T, Morita, H, Uno, Y, et. al.
    • Organizer
      66th Scientific Sessions of American Diabetes Associations
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2006-06-10
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Association between platelet aggregation and obesity index2006

    • Author(s)
      Sugiyama, C, Morita, H, Uno, Y, Ishizuka T, et. al.
    • Organizer
      66th Scientific Sessions of American Diabetes Associations
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2006-06-10
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Association of evity factors with blood pressure, ability of exercise or glucose tolerance2006

    • Author(s)
      Ishizuka, T, Matsumoto, M, Morita, H, Uno, Y, et. al.
    • Organizer
      66th Scientific Sessions of American long Diabetes Associations
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2006-06-09
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Effect of dehydroepiandrosterone(DHEA)on insulin resistance and DHEA-sulfate concentration in male adults of Japanese longevity district2005

    • Author(s)
      Ishizuka T, Morita H, Uno Y, et. al.
    • Organizer
      41st Annual Meeting of the European Association for the Study of Diabetes
    • Place of Presentation
      Athens, Greece
    • Year and Date
      20050912-15
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Dehydroepiandrosterone-induced improvement of insulin resistance in rat adipocytes and its clinical significance in male adults2005

    • Author(s)
      Ishizuka T, Morita H, Uno Y, et. al.
    • Organizer
      65th Scientific Sessions of American Diabetes Associations
    • Place of Presentation
      San Diego, USA
    • Year and Date
      20050610-14
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Platelet aggregation in obese and diabetic subjects-association with leptin level2005

    • Author(s)
      Sugiyama C, Morita H, Uno Y, Ishizuka T, et. al.
    • Organizer
      65th Scientific Sessions of American Diabetes Associations
    • Place of Presentation
      San Diego, USA
    • Year and Date
      20050610-14
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Relationship between depressive scale and lifestyle in new outpatients2005

    • Author(s)
      Morita H, Uno Y, Ishizuka T, et. al.
    • Organizer
      WONCA Asia Pacific Regional Conference
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      20050527-31
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Effect of dehydroepiandrosterone (DHEA) on insulin resistance and DHEA-sulfate concentration in male adults of Japanese longevity district2005

    • Author(s)
      Ishizuka, T, Morita, H, Uno, Y, et. al.
    • Organizer
      41st Annual Meeting of the European Association for the Study of Diabetes
    • Place of Presentation
      Athens, Greece
    • Year and Date
      2005-09-13
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Platelet aggregation in obese and diabetic subjects-association with leptin Level2005

    • Author(s)
      Sugiyama, C, Morita, H, Uno, Y, T, Ishizuka, T, et. al.
    • Organizer
      65th Scientific Sessions of American Diabetes Associations
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2005-06-11
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Relationship between depressive scale and lifestyle in new outpatients2005

    • Author(s)
      Morita, H, Uno, Y, Ishizuka, T, et. al.
    • Organizer
      WONCA Asia Pacific Regional Conference 2005
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2005-05-28
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] The Association of dehydroepiandrosterone with insulin sensitivity of male adults and longevity in Japan2004

    • Author(s)
      Ishizuka T, Morita H, Uno Y, et. al.
    • Organizer
      64th Scientific Sessions of American Diabetes Associations
    • Place of Presentation
      Orlando, USA
    • Year and Date
      20040604-08
    • Description
      「研究成果報告書概要(和文)」より

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Published: 2010-02-04  

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