先端モデル動物支援プラットフォーム

2019 Fiscal Year Annual Research Report

• Project/Area Number: 16H06276
• Research Institution: The University of Tokyo
• Principal Investigator: 井上 純一郎 東京大学, 医科学研究所, 教授
• Project Period (FY): 2016 – 2021
• Keywords: モデル動物作製 / ゲノム編集 / 病理形態解析 / 生理機能解析 / 分子探索・プロファイリング

Outline of Annual Research Achievements

①総括支援活動 : 各支援事業の公募をホームページにおいて一元化しているが、本年度は英文での案内を充実させるなど、利便性の一層の向上に努めた。9月5～7日に蓼科において開催した若手支援技術講習会では、92名の若手研究者が参加し活発な発表と情報交換を行った。成果発表会を2月4～5日に大津市で行い、被支援者による研究成果を中心に132名の参加者による先端的な研究紹介があった。
②モデル動物作製支援活動 : 前・後期2回の公募で申請のあった計144件の課題について一次・二次審査を行い、学術的に優れた83件の課題を採択した。それぞれの採択者と個別に協議し、最適な遺伝子改変技術を用いて、遺伝子改変マウスおよびラットを迅速に作製し、研究リソースとして提供した。
③病理形態解析支援活動 : 34件の申請を受け、3回の審査の結果、28件に関して病理形態解析を実施した。研究の方向性を裏付ける多くの成果が得られた。論文の図の作成など、論文が受理されるまで支援を実施した。
④生理機能解析支援活動 : 行動学的解析では24課題、薬理学的解析では11課題、光技術による操作解析では6課題、多機能電極・計測データ解析では11課題をそれぞれ支援し、動物モデルにおける病態・生理学的基盤の解明推進を支援することで、Cell誌などに成果が発表された。
⑤分子プロファイリング支援活動 : 依頼化合物の分子プロファイリング238件、阻害剤キット配付81枚、RNA干渉キット配付・siRNAデザイン合成41件、バーコードshRNAライブラリーによる化合物の標的経路探索18件を実施するとともに、要望に応じて実地指導を行い、解析技術を習得させた。

Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

①総括支援活動 : 若手支援技術講習会では、先進ゲノム支援との連携も行われた。成果発表会とともに多くの参加希望者があり、参加者の研究分野の多様性が増して、本支援活動が生命科学の広い分野から注目を集めていることが明示された。
②モデル動物作製支援活動 : 増加傾向にある応募課題に対し、最新技術を導入することで効率化を図り、予算範囲内で最大限の課題数を採択した。遺伝子改変が複雑あるいは困難な課題を進めるために、必要な技術を導入もしくは開発した。年度末には、新型コロナウイルス感染拡大防止策の一環として動物受け入れが困難な施設が出てきたが、支援拠点で凍結胚を作製し、一時保管することなどにより対応した
③病理形態解析支援活動 : 申請数は安定しており、事前相談や再審査によりできるだけ多く若手研究者の支援を行うよう努力している。現在の予算ならびに班員のエフォートにおいてできる最大限の支援活動を実施しており、成果は確実に上がっている。
④生理機能解析支援活動 : モデルマウスを対象にした感覚・運動・認知機能に関わる「網羅的行動テストバッテリー」を用いた行動解析支援を24課題、依存性薬物等の感受性に関連する行動解析および臨床データと遺伝子多型との関連解析を行う規制薬物作用解析支援を11課題、進展著しい光遺伝学に関する最新技術を活用した研究支援を6課題、多機能集積化電極による最先端の技術提供を行う多元的生理機能計測操作支援を11課題で実施した。
⑤分子プロファイリング支援活動 : トライアル的な小規模の課題から構造活性相関など大規模な課題まで、幅広く支援できた。化合物評価支援では被支援者の研究室から学生を派遣してもらい、技術習得させるなど若手育成面でも成果があった。分子探索支援においても、標準阻害剤キットを利用後に改めて寄託化合物ライブラリーを希望するなど、支援成果をもとにさらなる高次支援に展開する被支援者が見られた。

Strategy for Future Research Activity

①総括支援活動 : 支援拠点の活動内容や支援による成果の紹介など、ホームページを用いた広報活動を一層推進する。若手研究者に対してモデル動物の作製や解析の指導を継続する。成果発表会では、支援による成果の紹介を足掛かりにした新たな共同研究の進展を図る。
②モデル動物作製支援活動 : 先端的なゲノム編集技術を用いて、依頼者の要望に応じて遺伝子改変動物を作製・提供し、科研費による学術研究を支援する。さらに、各支援拠点がもつ独自性の高い研究リソースを提供し、また遺伝子改変技術および周辺技術の導入・開発を進めることにより、国内の研究レベル向上に貢献する。作製された遺伝子改変動物は、公共リソースバンクに供出し、学術基盤としての研究リソースの整備を推進する。
③病理形態解析支援活動 : 現状では、予算ならびに班員に関して限界が近い状態となっている。今後は審査をより厳格に行い、少額研究費の若手の申請に十分に対応したい。一旦開始した病理形態支援は論文が受理されるまでサポートする、という基本方針に変化はない。
④生理機能解析支援活動 : 引き続き各拠点における技術力の維持・向上、支援課題の公正な選考、ハイレベルな支援実施体制の継続に努める。また、支援事業の認知度向上のため、学会等での広報活動を行う。技術支援にとどまらず、支援該当部の論文分担執筆を積極的に進め、成果の公表にも貢献する。
⑤分子プロファイリング支援活動 : 前年度に引き続き、広報の強化・解析条件のカスタマイズ対応・支援実施後のフォロー(科学的助言、共同研究の斡旋、高次支援の勧奨)に努める。定例班会議で問題点を洗い出し、常に最善の運用体制で支援を実施する。また、支援担当者と被支援者による共同研究への移行も意識したうえで、適宜展開例を提示しながら支援を進める。
今年度は、新型コロナの影響により活動内容の変更も予想される。幹事班長会議で連携の上対応する予定である。

Research Products

• [Int'l Joint Research] Yale University/Stanford University/Johns Hopkins University(アメリカ)
  • Country Name: アメリカ
  • Counterpart Institution: Yale University/Stanford University/Johns Hopkins University
  • # of Other Institutions: 9
• [Int'l Joint Research] University of Ottawa/University of Toronto(カナダ)
  • Country Name: CANADA
  • Counterpart Institution: University of Ottawa/University of Toronto
• [Int'l Joint Research] Helmholtz Zentrum Muenchen/Technische Universitaet Muenchen(ドイツ)
  • Country Name: GERMANY
  • Counterpart Institution: Helmholtz Zentrum Muenchen/Technische Universitaet Muenchen
• [Int'l Joint Research] Pohang University of Science and Technology(シンガポール)
  • Country Name: SINGAPORE
  • Counterpart Institution: Pohang University of Science and Technology
• [Int'l Joint Research] 南通大学(中国)
  • Country Name: CHINA
  • Counterpart Institution: 南通大学
• [Int'l Joint Research]
  • # of Other Countries: 3
• [Journal Article] The role of calcium metabolism in keratinocyte differentiation (2020)
  • Author(s): Okumura K, Wakabayashi Y
  • Journal Title: Trends in Cancer Research Volume: 14 Pages: 45-47
  • Peer Reviewed / Open Access
• [Journal Article] A central master driver of psychosocial stress responses in the rat. (2020)
  • Author(s): Kataoka, N., Shima, Y., Nakajima, K., Nakamura, K.
  • Journal Title: Science Volume: 367 Pages: 1105-1112
  • DOI: 10.1126/science.aaz4639
  • Peer Reviewed
• [Journal Article] Aberrant Cortical Ensembles and Schizophrenia-like Sensory Phenotypes in Setdla+/-Mice. (2020)
  • Author(s): Hamm JP, Shymkiv Y, Mukai J, Gogos JA, Yuste R.
  • Journal Title: Biological Psychiatry
  • DOI: 10.1016/j.biopsych.2020.01.004
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Acute restraint stress augments the rewarding memory of cocaine through activation of α1 adrenoceptors in the medial prefrontal cortex of mice (2020)
  • Author(s): Wada S, Yanagida J, Sasase H, Zhang T, Li X, Kamii H, Domoto M, Deyama S, Hinoi E, Yamanaka A, Nishitani N, Nagayasu K, Kaneko S, Minami M, Kaneda K
  • Journal Title: Neuropharmacology Volume: 166 Pages: 107968
  • DOI: 10.1016/j.neuropharm.2020.107968
  • Peer Reviewed
• [Journal Article] Adiponectin receptor 1 gene is potentially associated with severity of postoperative pain but not cancer pain (2020)
  • Author(s): Ninagawa J. Sumitani M, Nishizawa D, Nagashima M, Mietani K, Abe H, Inoue R, Hozumi J, Tsuchida R, Ikeda K, Yamada Y
  • Journal Title: Medicine (Baltimore) Volume: 99 Issue: 5 Pages: e18924
  • DOI: 10.1097/MD.0000000000018924
  • Peer Reviewed / Open Access
• [Journal Article] Anosmin-l activates vascular endothelial growth factor receptor and its related signaling pathway for olfactory bulb angiogenesis. (2020)
  • Author(s): Matsushima S, Shimizu A, Kondo M, Asano H, Ueno N, Nakayama H, Sato N, Komeno M, Ogita H, Kurokawa-Seo M.
  • Journal Title: Sci Rep Volume: 10 Pages: 188
  • DOI: 10.1038/s41598-019-57040-3
  • Peer Reviewed / Open Access
• [Journal Article] BRUP-1, an intracellular bilirubin modulator, exerts neuroprotective activity in a cellular Parkinson's disease model. (2020)
  • Author(s): Kataura T, Saiki S, Ishikawa K, Akamatsu W, Sasazawa Y, Hattori N, Imoto M
  • Journal Title: J. Neurochemstry
  • DOI: 10.1111/jnc.14997
  • Peer Reviewed
• [Journal Article] Cataloguing and selection of mRNAs localized to dendrites in neurons and regulated by RNA-binding proteins in RNA granules (2020)
  • Author(s): R Ohashi and N Shiina
  • Journal Title: Biomolecules Volume: 10 Pages: 167
  • DOI: 10.3390/biom10020167
  • Peer Reviewed / Open Access
• [Journal Article] Clinical features of early myoclonic encephalopathy caused by a CDKL5 mutation. (2020)
  • Author(s): Takeda K, Miyamoto Y, Yamamoto H, Ishii A, Hirose S, Yamamoto H.
  • Journal Title: Brain Dev. Volume: 42 Issue: 1 Pages: 73-76
  • DOI: 10.1016/j.braindev.2019.08.003
  • Peer Reviewed
• [Journal Article] Clinical significance of soluble CADM1 as a novel marker for adult T-cell leukemia/lymphoma. (2020)
  • Author(s): Nakahata S, et al, Saito M, Morishita K.
  • Journal Title: Haematologica
  • DOI: 10.3324/haematol.2019.234096
  • Peer Reviewed / Open Access
• [Journal Article] Coordinated Changes in Cell Membrane and Cytoplasm During Maturation of Apoptotic Bleb (2020)
  • Author(s): Kana Aoki, Shinsuke Satoi, Shota Harada, Seiichi Uchida, Yoh Iwasa, Junichi Ikenouchi
  • Journal Title: Mol Biol Cell
  • DOI: 10.1091/mbc.E19-12-0691
  • Peer Reviewed
• [Journal Article] Crystal structure of Drosophila Piwi (2020)
  • Author(s): Yamaguchi S. Oe A, Nishida KM, Yamashita K, Kajiya A, Hirano S, Matsumoto N, Dohmae N, Ishitani R, Saito K, Siomi H, Nishimasu H, Siomi MC. Nureki O.
  • Journal Title: Nature Communications Volume: 11 Issue: 1 Pages: 858
  • DOI: 10.1038/s41467-020-14687-1
  • Peer Reviewed / Open Access
• [Journal Article] Deficiency of ascorbic acid decreases the contents of tetrahydrobiopterin in the liver and the brain of ODS rats. (2020)
  • Author(s): Takeshita N, Kawade N, Suzuki W, Hara S, Horio F, Ichinose H
  • Journal Title: Neurosci Lett Volume: 715 Pages: 134656
  • DOI: 10.1016/j.neulet.2019.134656
  • Peer Reviewed
• [Journal Article] Differential cortical and subcortical projection targets of subfields in the core region of mouse auditory cortex. (2020)
  • Author(s): Nakata S. Takemoto M, Song W-J.
  • Journal Title: Hearing Research Volume: 386 Pages: 107876
  • DOI: 10.1016/j.heares.2019.107876
  • Peer Reviewed
• [Journal Article] Establishment and characterization of highly osteolytic luminal breast cancer cell lines by intra-caudal arterial injection (2020)
  • Author(s): Han Y, Nakayama J, Hayashi Y, Jeong S, Futakuchi M, Ito E, Watanabe S and Semba K
  • Journal Title: Genes to Cells Volume: 25 Pages: 111-123
  • DOI: 10.1111/gtc.12743
  • Peer Reviewed
• [Journal Article] FARP1 boosts CDC42 activity from integrin αvβ5 signaling and correlates with poor prognosis of advanced gastric cancer. (2020)
  • Author(s): Hirano T, Shinsato Y, Tanabe K, Higa N, Kamil M, Kawahara K, Furukawa T & Shoji Natsugoe, et al.
  • Journal Title: Oncogenesis Volume: 9 Pages: 13
  • DOI: 10.1038/s41389-020-0190-7
  • Peer Reviewed / Open Access
• [Journal Article] FKBP8 LIRL-dependent mitochondrial fragmentation facilitates mitophagy under stress conditions. (2020)
  • Author(s): Yoo SM, Yamashita SI, Kim H, Na D, Lee H, Kim SJ, Cho DH, Kanki T, Jung YK.
  • Journal Title: FASEB J. Volume: 34 Issue: 2 Pages: 2944-2957
  • DOI: 10.1096/fj.201901735R
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Formin-like 1 (FMNL1) Is Associated with Glioblastoma Multiforme Mesenchymal Subtype and Independently Predicts Poor Prognosis. (2020)
  • Author(s): Higa N, Shinsato Y, Kamil M, Hirano T, Takajo T, Shimokawa M, Minami K, Yamamoto M, Kawahara K, Yonezawa H, Hirano H, Furukawa T, Yoshimoto K and Arita K
  • Journal Title: Int J Mol Sci Volume: 20 Pages: 6355
  • DOI: 10.3390/ijms20246355
  • Peer Reviewed / Open Access
• [Journal Article] Gemcitabine induces Parkin-independent mitophagy through mitochondrial-resident E3 ligase MUL1-mediated stabilization of PINK1. (2020)
  • Author(s): Igarashi R, Yamashita SI, Yamashita T, Inoue K, Fukuda T, Fukuchi T, Kanki T.
  • Journal Title: Sci Rep. Volume: 10 Issue: 1 Pages: 1465
  • DOI: 10.1038/s41598-020-58315-w
  • Peer Reviewed / Open Access
• [Journal Article] Identification and characterization of the binding sequences and target genes of p53 lacking the lst transactivation domain. (2020)
  • Author(s): Shiori Suzuki#, Shuichi Tsutsumi#, Yu Chen#, Chikako Ozeki, Atsushi Okabe, Tatsuya Kawase, Hiroyuki Aburatani and Rieko Ohki*.
  • Journal Title: Cancer Science Volume: 111 Pages: 451-466
  • DOI: 10.1111/cas.14279
  • Peer Reviewed / Open Access
• [Journal Article] Identification and functional characterisation of N-linked glycosylation of the orphan G protein-coupled receptor Gpr176. (2020)
  • Author(s): Wang T, Nakagawa S, Miyake T, Setsu G, Kunisue S, Goto K, Hirasawa A, Okamura H, Yamaguchi Y, and Doi M
  • Journal Title: Sci. Rep. Volume: 10 Pages: 4429
  • DOI: 10.1038/s41598-020-61370-y
  • Peer Reviewed / Open Access
• [Journal Article] Identification of a small compound targeting PKM2-regulated signaling using 2D gel electrophoresis-based proteome-wide CETSA. (2020)
  • Author(s): Nagasawa I, Muroi M, Kawatani M, Ohishi T, Ohba SI, Kawada M, Osada H.
  • Journal Title: Cell Chemical Biology Volume: 27 Pages: 186-196.e4
  • DOI: 10.1016/j.chembiol.2019.11.010
  • Peer Reviewed
• [Journal Article] Identification of Transmembrane Protein 168 Mutation in Familial Brugada Syndrome. (2020)
  • Author(s): Shimizu A, Zankov DP, Sato A, Komeno M, Toyoda F, ..., Ogita H.
  • Journal Title: FASEB J Volume: 34 Issue: 5 Pages: 6399-6417
  • DOI: 10.1096/fj.201902991R
  • Peer Reviewed
• [Journal Article] In vivo delivery of an exogenous molecule into murine T lymphocytes using a lymphatic drug delivery system combined with sonoporation. (2020)
  • Author(s): Kato S., Shirai Y., Motozono, C., Kanzaki, H., Mori, S., Kodama, T.
  • Journal Title: Biochem Biophys Res Commun. Volume: 525 Issue: 4 Pages: 1025-1031
  • DOI: 10.1016/j.bbrc.2020.02.174
  • Peer Reviewed
• [Journal Article] Involvement of ribosomal protein L11 expression in sensitivity of gastric cancer against 5-FU (2020)
  • Author(s): Kawahata T, Kawahara K, Shimokawa M, Sakiyama A, Shiraishi T, Minami K, Yamamoto M, Shinsato Y, Arima K, Hamada T, Furukawa T
  • Journal Title: ONCOLOGY LETTERS Volume: 19 Pages: 2258-2264
  • DOI: 10.3892/ol.2020.11352
  • Peer Reviewed / Open Access
• [Journal Article] Isoform-dependent subcellular localization of LMTK1A and LMTK1B, and their roles in axon outgrowth and spine formation. (2020)
  • Author(s): Wei R, Sugiyama A, Sato Y, Nozumi M, Nishino H, Takahashi M, Saito T, Ando K, Fukuda M, Tomomura M, Igarashi M, *Hisanaga S-i
  • Journal Title: J Biochem
  • DOI: 10.1093/jb/mvaa019
  • Peer Reviewed
• [Journal Article] Lamellarin alkaloids : Isolation, synthesis, and biological activity (2020)
  • Author(s): Tsutomu Fukuda, Fumito Ishibashi, Masatomo Iwao
  • Journal Title: The Alkaloids : Chemistry and Biology Volume: 83 Pages: 1-112
  • DOI: 10.1016/bs.alkal.2019.10.001
  • Peer Reviewed
• [Journal Article] Localization Mechanism of Myosin Id, an ASD Risk Gene Product in Dendritic Spines (2020)
  • Author(s): Tetsuya Sasaki, Yosuke Takei
  • Journal Title: Jap J Biological Psych. Volume: 31 Issue: 2
  • Peer Reviewed
• [Journal Article] MDGA1-deficiency attenuates prepulse inhibition with alterations of dopamine and serotonin metabolism : An ex vivo HPLC-ECD analysis. (2020)
  • Author(s): Hossain MR, Jamal M, Tanoue Y, Ojima D, Takahashi H, Kubota T, Ansary TM, Ito A, Tanaka N, Kinoshita H, Kishimoto Y, Yamamoto T
  • Journal Title: Neurosci, Lett. Volume: 716 Pages: 134677
  • DOI: 10.1016/j.neulet.2019.134677
  • Peer Reviewed
• [Journal Article] MEIOSIN directs the switch from mitosis to meiosis in mammalian germ cells (2020)
  • Author(s): Ishiguro K (Corresponding), Matsuura K, Tani N, Takeda N, Usuki S, Yamane M, Sugimoto M, Fujimura S, Hosokawa M, Chuma S, Ko S. H. M. Araki K, Niwa H
  • Journal Title: Developmental Cell Volume: 52 Issue: 4 Pages: 429-445
  • DOI: 10.1016/j.devcel.2020.01.010
  • Peer Reviewed
• [Journal Article] Microinjection support system for small biological subject (2020)
  • Author(s): Sugimoto Y., Naniwa K., Aonuma H. and Osuka K.
  • Journal Title: HardwareX Pages: e00103
  • DOI: 10.1016/j.ohx.2020.e00103
  • Peer Reviewed
• [Journal Article] More dynamic, more quantitative, unexpectedly intricate : Advanced understanding on synaptic RNA localization in learning and memory (2020)
  • Author(s): R Roy, N Shiina, and D O Wang
  • Journal Title: Neurobiology of Learning and Memory Volume: 168 Pages: 107149-107149
  • DOI: 10.1016/j.nlm.2019.107149
  • Peer Reviewed
• [Journal Article] Myeloid-derived suppressor cells are essential partners for immune checkpoint inhibitors in the treatment of cisplatin-resistant bladder cancer (2020)
  • Author(s): 武山祐士、加藤実、清水保臣、東由香里、玉田聡、井口太郎、山崎健史、魏民、鰐渕英機、仲谷達也
  • Journal Title: Cancer Letters
  • DOI: 10.1016/j.canlet.2020.03.013
  • Peer Reviewed
• [Journal Article] NBR1-mediated p62-liquid droplets enhance the Keap1-Nrf2 system. (2020)
  • Author(s): Sanchez-Martin P, Sou YS, Kageyama S, Koike M, Waguri S, *Komatsu M.
  • Journal Title: EMBO Rep. Volume: 21 Pages: e48902
  • DOI: 10.15252/embr.201948902
  • Peer Reviewed / Open Access
• [Journal Article] Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes. (2020)
  • Author(s): Matsumura K, Nakazawa T, et al.
  • Journal Title: Nat Commun Volume: 11 Pages: 859
  • DOI: 10.1038/s41467-020-14697-z
  • Peer Reviewed / Open Access
• [Journal Article] PD-L1/L2 protein levels rapidly increase on monocytes via trogocytosis from tumor cells in classical Hodgkin lymphoma. (2020)
  • Author(s): Kawashima M, Carreras J, Higuchi H, et al
  • Journal Title: Leukemia.
  • DOI: 10.1038/s41375-020-0737-9
  • Peer Reviewed
• [Journal Article] Retinal ganglion cell loss in 1 kinesin-1 cargo Alcadein α deficient mice. (2020)
  • Author(s): Nakano Y, Hirooka K, Chiba Y, Ueno M, Ojima D, Hossain MR, Takahashi H, Yamamoto T, Kiuchi Y
  • Journal Title: Cell Death Dis. Volume: 11 Issue: 3 Pages: 166
  • DOI: 10.1038/s41419-020-2363-x
  • Peer Reviewed / Open Access
• [Journal Article] Role of metastasis-related genes in cisplatin chemoresistance in gastric cancer (2020)
  • Author(s): Nishiguchi Y, Oue N, Fujiwara-Tani R, Sasaki T, Ohmori H, Kishi S, Shiori Mori S, Mori T, Ideda N, Matsumoto S, Wakatsuki K, Luo Y, Yasui W, Sho M, Kuniyasu H
  • Journal Title: Int J Mol Sci Volume: 21 Pages: 254
  • DOI: 10.3390/ijms21010254
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Role of plasminogen activator inhibitor-1 in methotrexate-induced epithelial-mesenchymal transition in alveolar epithelial A549 cells (2020)
  • Author(s): Yohei Yamagami, Masashi Kawami, Takamichi Ojima, Sora Futatsugi, Ryoko Yumoto, Mikihisa Takano
  • Journal Title: Biochem Biophys Res Commun Volume: 525 Issue: 3 Pages: 543-548
  • DOI: 10.1016/j.bbrc.2020.02.131
  • Peer Reviewed
• [Journal Article] Structural insights into selective interaction between type IIa receptor protein tyrosine phosphatases and Liprin-α. (2020)
  • Author(s): Wakita M, Yamagata A, Shiroshima T, Izumi H, Maeda A, Sendo M, Imai A, Kubota K, Goto-Ito S, Sato Y, Mori H, Yoshida T, Fukai S.
  • Journal Title: Nature Communications Volume: 11 Pages: 649
  • DOI: 10.1038/s41467-020-14516-5
  • Peer Reviewed / Open Access
• [Journal Article] Subquinocin. a small molecule inhibitor of CYLD and USP-family deubiquitinating enzymes, promotes NF-κB signaling. (2020)
  • Author(s): Yamanaka S, Sato Y, Oikawa D, Goto E, Fukai S, Tokunag F, Sawasaki T.
  • Journal Title: Biochem Biophys Res Commun. Volume: 524 Issue: 1 Pages: 1-7
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• [Journal Article] (S)-norketamine and (2S, 6S)-hydroxynorketamine Exert Potent Antidepressant-Like Effects in a Chronic Corticosterone-Induced Mouse Model of Depression (2020)
  • Author(s): 横山 玲、樋口 桃子、田邊 航、塚田 信司、内藤 恵、Lu Chen、笠井 淳司、勢力 薫、中澤 敬信、中川 晋作、橋本 謙二、橋本 均、吾郷 由希夫
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  • DOI: 10.1158/1535-7163.MCT-19-0668
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• [Journal Article] Tankyrase promotes primary precursor miRNA processing to precursor miRNA (2020)
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• [Journal Article] Targeting claudin-4 enhances chemosensitivity in breast cancer. (2020)
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• [Journal Article] 直鎖状ユビキチン鎖の神経変性疾患への関与とLUBAC阻害剤の開発 (2020)
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  • Journal Title: 生化学 Volume: 91 Pages: 28-34
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• [Journal Article] (R)-Ketamine Induces a Greater Increase in Prefrontal 5-HT Release Than (S)-Ketamine and Ketamine Metabolites via an AMPA Receptor-Independent Mechanism (2019)
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• [Journal Article] Abnormal axon guidance signals and reduced interhemispheric connection via anterior commissure in neonates of marmoset ASD model. (2019)
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  • Journal Title: Neuroimage Volume: 0.26041666667 Pages: 243-251
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• [Journal Article] AMPA受容体の分子修飾変化とてんかん (2019)
  • Author(s): 林 崇
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• [Journal Article] Autism-associated protein kinase D2 regulates embryonic cortical neuron development. (2019)
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• [Journal Article] Cue-dependent safety and fear learning in a discriminative auditory fear conditioning paradigm in the mouse. (2019)
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• [Journal Article] Decentralized control mechanism for determination of moving direction in brittle stars with penta-radially symmetric body (2019)
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• [Journal Article] Enhanced emotional memory retrieval by chemogenetic activation of locus coeruleus norepinephrine neurons. (2019)
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• [Journal Article] Fatty acid desaturase 2 is up-regulated by the treatment with statin through geranylgeranyl pyrophosphate-dependent Rho kinase pathway in HepG2 cells. (2019)
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  • Author(s): Keisuke Otake, Kana Yamada, Kazuki Miura, Yukiko Sasazawa, So Miyazaki, Yuki Niwa, Akihiro Ogura, Ken-ichi Takao, Siro Simizu
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• [Journal Article] IER5 Is a p53-Regulated Activator of HSF1 That Contributes to Promotion of Cancer. (2019)
  • Author(s): Tatsuya Kawase, Yu Chen, Ricko Ohki*.
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• [Journal Article] Locomotor kinematics and EMG activity during quadrupedal versus bipedal gait in the Japanese macaque (2019)
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• [Journal Article] Multiple neuronal circuits for variable objcct-action choices based on short-and long-term memories. (2019)
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• [Journal Article] Newborn screening for Pompe disease in Japan : report and literature review of mutations in the GAA gene in Japanese and Asian patients. (2019)
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  • Author(s): Shotaro Yamano, Makoto Kimura, Yu Chen, Naoko Imamoto* and Rieko Ohki*.
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• [Journal Article] Nuclear RNA cxport factor variant initiates piRNA-guided co-transcriptional silencing (2019)
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• [Journal Article] PRRT2 mutations in Japanese patients with benign infantile epilepsy and paroxysmal kinesigenic dyskinesia. (2019)
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• [Journal Article] Psychiatric-disorder-related behavioral phenotypes and cortical hyperactivity in a mouse model of 3q29 deletion syndrome. (2019)
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• [Journal Article] Reduced chain length in myelin sphingolipids and poorer motor coordination in mice deficient in the fatty acid elongase Elovll. (2019)
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• [Journal Article] SIRT7 regulates the nuclear export of NF-kB p65 by deacetylating Ran. (2019)
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• [Journal Article] Social defeat stress-specific increase in c-Fos expression in the extended amygdala in mice : Involvement of dopamine D1 receptor in the medial prefrontal cortex. (2019)
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  • Author(s): Shinohara, F., Asaoka, Y., Kamii, H., Minami, M., Kaneda, K.
  • Journal Title: Addiction Biology Volume: 24 Pages: 509-521
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• [Journal Article] Suzuki-Miyaura Cross-Coupling of 1.8-Diaminonaphthalene (dan)-Protected Arylboronic Acids (2019)
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• [Journal Article] Synthesis and properties of anionic ruthenium thionitrosyl and selenonitrosyl complexes that contain tetraanionic 2-hydroxybenzamidobenzene ligands (2019)
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• [Journal Article] Synthesis of Helical 3,3' -Bridged-2,2' -bibenzo[g]quinolines (2019)
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• [Journal Article] Synthesis of lactone-fused pyrroles by ruthenium-catalyzed 1,2-carbon migration-cycloisomerization (2019)
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• [Journal Article] Targeting claudin-4 enhances CDDP-chemosensitivity of gastric cancer (2019)
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• [Journal Article] Transgenic Archaerhodopsin-3 Expression in Hypocretin/Orexin Neurons Engenders Cellular Dysfunction and Features of Type 2 Narcolepsy. (2019)
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  • Peer Reviewed / Open Access
• [Journal Article] Whole-brain Block-Face Serial Microscopy Tomography at Subcellular Resolution Using FAST (2019)
  • Author(s): 勢力 薫、笠井 淳司、中澤 敬信、丹生 光咲、中 雄一郎、田沼 将人、五十嵐 久人、山浦 港生、早田 敦子、吾郷 由希夫、橋本均
  • Journal Title: Nat Protoc Volume: 14 Issue: 5 Pages: 1509-1529
  • DOI: 10.1038/s41596-019-0148-4
  • Peer Reviewed
• [Journal Article] Zn (OTf)2-mediated annulations of N-propargylated tetrahydrocarbolines : divergent synthesis of four distinct alkaloidal scaffolds (2019)
  • Author(s): Sadaiwa Yorimoto, Akira Tsubouchi, Haruki Mizoguchi, Hideaki Oikawa, Yoshiaki Tsunekawa, Tomoya Ichino, Satoshi Maeda and Hiroki Oguri
  • Journal Title: Chemical Science Volume: 10 Pages: 5686-5698
  • DOI: 10.1039/C9SC01507H
  • Peer Reviewed / Open Access
• [Journal Article] 骨転移とマイクロRNA (2019)
  • Author(s): 佐藤信吾
  • Journal Title: BIO Clinica Volume: 34 Issue: 9 Pages: 794-798
• [Journal Article] 定量的マンガン造影MRIを用いた疾患モデル動物の神経活動計測 (2019)
  • Author(s): 菊田 里美, 笠原 二郎, 小山内 実
  • Journal Title: 日本放射線技術学会雑誌 Volume: 75 Issue: 8 Pages: 799-804
• [Presentation] 2DE-CETSAを用いたPKM2制御シグナルに作用する化合物NPD10084の同定 (2020)
  • Author(s): 室井 誠、永澤 生久子、小川 直子、川谷 誠、大石 智一、大庭 俊一、川田 学、長田 裕之
  • Organizer: 日本農芸化学会2020年度大会
• [Presentation] Activity of low contrast-preferring neurons in rat primary visual cortex during an orientation discrimination task. (2020)
  • Author(s): Kimura R, Yoshimura Y
  • Organizer: UK-Japan Neuroscience Symposium 2020
  • Int'l Joint Research / Invited
• [Presentation] Analysis of the effect of IL17A increase on neurodevelopment in RORgt-overexpression transgenic mice. (2020)
  • Author(s): Saki Tome, Tetsuya Sasaki, Yosuke Takei.
  • Organizer: Inauguration Symposium for the Neuroscience Program
  • Int'l Joint Research
• [Presentation] Area-specific laminar organization is regulated by thalamocortical axons through axon-derived secretory protein VGF in developing neocortex (2020)
  • Author(s): Haruka Sato
  • Organizer: 日本発生生物学会第53回年会
• [Presentation] CH/π相互作用に着目したaplysiatoxin単純化アナログの合成と生物活性 (2020)
  • Author(s): 小林巧実、入江一浩
  • Organizer: 2020年度日本農芸化学会大会
• [Presentation] Compartmentalized input-output organization of cerebellar Lugaro cells, as revealed using knockin-mediated yellow cameleon reporter mice (2020)
  • Author(s): Taisuke Miyazaki, Miwako Yamasaki, Kenji F. Tanaka, Masahiko Watanabe
  • Organizer: 第125回日本解剖学会・全国学術集会
• [Presentation] Debromoaplysiatoxin単純化アナログ・10-Me-Aplog-1の側鎖長の最適化 (2020)
  • Author(s): 権田敦子、高田晃児、入江一浩
  • Organizer: 2020年度日本農芸化学会大会(九州大学、福岡市)
• [Presentation] Design of male infertility in mice (2020)
  • Author(s): Seiji Takashima, Kaito Masaki, Shunta Sakanishi, Shigeru Kyuwa, and Shigeru Kakuta
  • Organizer: The 5th Annual Meeting of Living Systems Design Research
  • Int'l Joint Research
• [Presentation] Development of novel drugs based on the pathomechanisms of developmental epileptic encephalopathy with disease specific induced pluripotent cells. (2020)
  • Author(s): Hirose S
  • Organizer: 2020 Educational Seminar of Genetic & Metabolic Diseases for Young Pediatricians
  • Invited
• [Presentation] DYRK2欠損マウスは先天性奇形症候群の疾患モデルとなる (2020)
  • Author(s): 與五沢里美、吉田清嗣
  • Organizer: 2019年度【先端モデル動物支援プラットフォーム】成果発表会
• [Presentation] Experimental targeted alpha-particle therapy against liver metastasis of HER2-positive gastric cancer in mice (2020)
  • Author(s): Sumitaka Hasegawa, Huizi Keiko Li
  • Organizer: American Association for Cancer Research (AACR) Annual Meeting 2020
  • Int'l Joint Research
• [Presentation] Low-contrast preference of activity in rat primary visual cortex during an orientation discrimination task. (2020)
  • Author(s): Kimura R, Yoshimura Y
  • Organizer: The Eighth International Neural Microcircuit Conference -Synaptic Specificity to Circuit Dynamics-
  • Int'l Joint Research
• [Presentation] Physiological roles of Prrt3, an orphan metabotropic receptor : Comprehensive behavioral test battery analysis using homozygous full gene knock-out mice derived from flox mice (2020)
  • Author(s): Yamamoto Tomomi, Hattori Satoko, Zhou Li, Natsume Rie, Konno Kohtarou, Chen I-Shan, Watanabe Masahiko, Sakimura Kenji, Miyakawa Tsuyoshi, Kubo Yoshihiro
  • Organizer: 第97回日本生理学会大会
• [Presentation] Protocadherin 10 delays developmental climbing fiber synapse elimination in a subset of aldolase C-positive Purkinje cells in the cerebellum (2020)
  • Author(s): Takaki Watanabe, Honoka Suzuki, Tsubasa Akamatsu, Kazuto Sakoori, Shutaro Inoue, Manabu Abe, Kenji Sakimura, Naofumi Uesaka, Masanobu Kano
  • Organizer: 第97回日本生理学会大会
• [Presentation] Regulation of neuronal heterochromatin structure by MeCP2 (2020)
  • Author(s): Aya Ito-Ishida
  • Organizer: UK-Japan Neuroscience Symposium
  • Int'l Joint Research / Invited
• [Presentation] Role of ferroptosis in carcinogenesis and tumor biology. (2020)
  • Author(s): Toyokuni S
  • Organizer: 17th Annual Meeting of the Society for Free Radical Research India (SFRR India) and the International Conference on Role and management of Oxidative Stress in Human Disease
  • Int'l Joint Research / Invited
• [Presentation] Selective turnover of p62-bodies through autophagy (2020)
  • Author(s): Masaaki Komatsu
  • Organizer: Autophagy and Lysosomes : function, signaling and diseases
  • Int'l Joint Research / Invited
• [Presentation] Telomere as the starting point of anticancer drug discovery (2020)
  • Author(s): Seimiya H
  • Organizer: LyonSE&N ? ELyT Workshop 2020
  • Int'l Joint Research / Invited
• [Presentation] The Developmental Defect of Serotonin Neuron Induced by Maternal immune activation. (2020)
  • Author(s): Jinmin Li, Fumihiro Shutoh, Tetsuya Sasaki, Yosuke Takei.
  • Organizer: 5th Anatomy Group Meeting
  • Invited
• [Presentation] The Endoplasmic reticulum protein Derlin-1 maintains neural stem cell populations in the adult hippocampus (2020)
  • Author(s): Naoya Murao, Hideki Nishitoh
  • Organizer: 第16回成体脳のニューロン新生懇談会
• [Presentation] TRPS1遺伝子の発現制御機構の解析 (2020)
  • Author(s): 阿部真土、佐伯直哉、波多賢二、宮崎紗理奈、立田小百合
  • Organizer: 2019年度先端モデル動物支援プラットフォーム成果発表会
• [Presentation] グアニン四重鎖特異的に蛍光を発するライトアップ型リガンドの創製 (2020)
  • Author(s): 綿谷成恭, 若林勇樹, 馬悦, 長澤和夫
  • Organizer: 日本化学会 第100回春季年会
• [Presentation] ストレス負荷で顕在化するホルモン輸送不全の謎 : 生活習慣病の危険因子としてのグラニンタンパク質欠損 (2020)
  • Author(s): 発表・研究代表者 : 穂坂正博 研究協力者 : 五味浩司、渡部剛
  • Organizer: 2019年度 【先端モデル動物支援プラットフォーム】成果発表会
• [Presentation] テトラヒドロビオプテリン生合成律速酵素GTPシクロヒドロラーゼⅠの転写調節機構 (2020)
  • Author(s): 宮木詩織, 原怜, 一瀬宏
  • Organizer: 日本ビタミン学会第72回大会
• [Presentation] ドーパミン代謝とジストニア・パーキンソニズムの発症機構 (2020)
  • Author(s): 一瀬宏
  • Organizer: 第18回ジストニア研究会
  • Invited
• [Presentation] フェルスター共鳴エネルギー移動の原理に基づく二光子励起用光遺伝学ツールの開発 (2020)
  • Author(s): 金城 智章、寺井 健太、堀田 彰一朗、野村 紀通、隅山 健太、岩田 想、富樫かおり、松田 道行
  • Organizer: 先端モデル動物支援プラットフォーム成果発表会
• [Presentation] ブルガダ症候群発症家系で見出された新たなTMEM168遺伝子変異の作用機序 (2020)
  • Author(s): 扇田久和
  • Organizer: 先端モデル動物支援プラットフォーム成果発表会
  • Invited
• [Presentation] ラットモデルを用いたNrf2活性化が引き起こす病態の解明 (2020)
  • Author(s): 田口恵子、山本雅之
  • Organizer: 第19回分子予防環境医学研究会
  • Invited
• [Presentation] リゾホスファチジン酸受容体1遺伝子多型は化学療法誘発性ニューロパチーの発症に関与する (2020)
  • Author(s): 住谷昌彦, 土田陸平, 西澤大輔, 池田和隆
  • Organizer: 2019年度先端モデル動物支援プラットフォーム成果発表会
• [Presentation] 化合物スクリーニングを用いた同所性乳がん肺高転移株の増殖機構解明 (2020)
  • Author(s): 中山淳, 林祐介, 仙波憲太郎
  • Organizer: 「先端モデル動物支援プラットフォーム」2019年度成果発表会
• [Presentation] 癌内線維芽細胞によるヒト乳癌細胞の浸潤・転移促進機構 (2020)
  • Author(s): 折茂 彰
  • Organizer: 2019年度先端モデルプラットホーム成果発表会
• [Presentation] 極長鎖スフィンゴ脂質の短鎖化によるミエリン厚低下と協調運動障害 (2020)
  • Author(s): 佐々貴之, 磯川昌志, 服部聡子, 宮川剛, 木原章雄
  • Organizer: 2019年度 先端モデル動物支援プラットフォーム 成果発表会
• [Presentation] 甲状腺未分化癌細胞におけるlenvatinibとIRAK1/4 inhibitor Ⅰの併用効果の検討 (2020)
  • Author(s): 川村佳史, 西條憲, 今井源, 石岡千加史
  • Organizer: 第24回日本がん分子標的治療学会 (予定)
• [Presentation] 鎖状型ポリオキサゾールリガンドの合成とテロメアグアニン四重鎖との相互作用解析 (2020)
  • Author(s): 佐々木捷悟, 鮑宏亮, 石塚匠, 徐岩, 寺正行, 馬悦, 長澤和夫
  • Organizer: 日本化学会 第100回春季年会
• [Presentation] 時間知覚・生成課題におけるサル前頭前野の神経細胞活動 (2020)
  • Author(s): 千葉惇、守田和紀、生塩研一、稲瀬正彦
  • Organizer: 第97回日本生理学会
• [Presentation] 自発行動がサルの時間知覚に与える影響 (2020)
  • Author(s): 望月圭、村田哲、稲瀬正彦
  • Organizer: 第97回日本生理学会
• [Presentation] 総腓骨神経を欠損する突然変異マウスの原因遺伝子の同定 (2020)
  • Author(s): 桝和子、加藤千賀、三谷優太、石井万由子、林康紀、村谷匡史、水野聖哉、杉山文博、高橋智、加藤秀樹、桝正幸
  • Organizer: 2019年度 先端モテ? ル動物支援フ? ラットフォーム 成果発表会
• [Presentation] 多色細胞系譜追跡法とsingle cell RNAseq を基点とした成体幹細胞の同定 (2020)
  • Author(s): 上野博夫
  • Organizer: 第5回細胞ダイバース公開シンポジウム
  • Invited
• [Presentation] 大環状へキサオキサゾール化合物の側鎖構造展開によるグアニン四重鎖に及ぼす蛍光特性の解析 (2020)
  • Author(s): 若林勇樹, 綿谷成恭, 齋藤良太, 寺正行, 馬悦, 長澤和夫
  • Organizer: 日本化学会 第100回春季年会
• [Presentation] 大脳皮質高次連合野を特徴づける遺伝子の解析 (2020)
  • Author(s): 佐々木哲也、小松勇介、武井陽介、山森哲雄
  • Organizer: 第125回 日本解剖学会総会・全国学術集会
• [Presentation] 中枢神経回路形成における染色体接着因子コヒーシンの機能 (2020)
  • Author(s): 藤田幸、山下俊英
  • Organizer: 第125回 日本解剖学会総会・全国学術集会
• [Presentation] 中枢神経系におけるⅠ1-17の役割の分子遺伝学的解析 (2020)
  • Author(s): 武井陽介、當銘幸貴、鮑培毅、高田拓弥、佐々木哲也
  • Organizer: 第125回 日本解剖学会総会・全国学術集会
• [Presentation] 天然物合成化学と生合成工学・超分子化学との融合を目指して (2020)
  • Author(s): 大栗博毅
  • Organizer: 産総研 第82回触媒化学融合研究センター講演会
  • Invited
• [Presentation] 分泌型プロテオグリカンTsukushiの欠損は神経幹細胞の制御不全を介して神経発達障害および水頭症を発症する (2020)
  • Author(s): 伊藤尚文, Shah Adii Ishtiyaq Ahmad, Mohammad Badrul Anam, 太田訓正
  • Organizer: 第42回日本分子生物学会
• [Presentation] Association of Rifl with nuclear membrane is essential for genome-wide replication timing regulation. (2019)
  • Author(s): H. Masai, Y. Kanoh, R. Fukatsu, S. Matsumoto, S. Kobayashi, H. Kato, A. Oji, S. Ito, N. Kakusho, K. Moriyama, I. Hiratani, N. Yoshizawa.
  • Organizer: Cold Spring Harbor Laboratory Meeting EUKARYOTIC DNA REPLICATION& GENOME MAINTENANCE
  • Int'l Joint Research / Invited
• [Presentation] まっすぐなユビキチン鎖を狙った創薬アプローチ (2019)
  • Author(s): 及川大輔
  • Organizer: 第9回CSJ化学フェスタ2019
  • Invited
• [Presentation] 20位を改変したアザラメラリンN誘導体の合成 (2019)
  • Author(s): 宮城一仁, 中野悠香, 福田勉, 小野寺玄, 木村正成
  • Organizer: 第56回化学関連支部合同九州大会
• [Presentation] 2次元電気泳動を用いた化合物に相互作用するたんぱく質の解析法(2DE-CETSA)の開発 (2019)
  • Author(s): 室井 誠、永澤 生久子、池野 あゆみ、小川 直子、川谷 誠、長田 裕之
  • Organizer: 日本農芸化学会2019年度大会
• [Presentation] 5-Aminolevulinic acid はミトコンドリア関連活性酸素種およびアポトーシスを介してヒト前立腺癌に放射線増感効果をもたらす (2019)
  • Author(s): 尾張拓也、三宅牧人、田中宣道、中井 靖、穴井 智、仲川嘉紀、國安弘基、藤本清秀
  • Organizer: 第35回前立腺シンポジウム
• [Presentation] A case of early myoclonic encephaloparthy with an SLC27A3 gene mutation (2019)
  • Author(s): Motonaga Y, Ishii A, Kawano H, Onda Y, Niimi T, Miyamoto T, Setoue T, nakamura M, Ohta E, Hirose S.
  • Organizer: 15th Asian Oceanian Congress of Child Neurology
  • Int'l Joint Research
• [Presentation] A novel model rat of chronic kidney disease (2019)
  • Author(s): Ohmori Iori, Mashimo Tomoji, Ouchida Mamoru, Toyokuni Shinya
  • Organizer: The 9th Federation of the Asian and Oceanian Physiological Societies Congress
  • Int'l Joint Research
• [Presentation] A novel UBL3 modification influences protein sorting to small extracellular vesicles (2019)
  • Author(s): Ageta H, Ageta-Ishihara N, Hitachi K, Onouchi T, Yamaguchi H, Yoshioka Y, Kosaka N, Ide T, Kinoshita M, Ochiya T, Setou M, Tsuchida K.
  • Organizer: ISEV2019
  • Int'l Joint Research / Invited
• [Presentation] A structural analysis based on kinetic model of trap-jaw in Odontomachus (2019)
  • Author(s): A. Matsuda, H. Aonuma and S. Kaneko
  • Organizer: AISM2019 (The 7th Asia International Symposium on Mechatronics)
  • Int'l Joint Research
• [Presentation] Activity- and septin-dependent extension of smooth ER into dendritic spines as a synaptic basis of memory consolidation (2019)
  • Author(s): 小坂優介、上田(石原)奈津実、深澤有吾、見学美根子、高雄敬三、宮川剛、尾藤晴彦、木下専
  • Organizer: 先端モデル動物支援プラットフォーム成果発表会
• [Presentation] Acute restraint stress augments the rewarding effect of cocaine through the activation of α1 adrenoceptors in the medial prefrontal cortex of mice (2019)
  • Author(s): Wada S, Yanagida J, Sasase H, Zhang T, Kamii H, Domoto M, Li X, Deyama S, Hinoi E, Yamanaka A, Nishitani N, Nagayasu K, Kaneko S, Minami M, Kaneda K
  • Organizer: Neuroscience 2019-Society for neuroscience
  • Int'l Joint Research
• [Presentation] Alcadeinα欠損マウスにおけるAPPのアミロイド生成的代謝の促進機構 (2019)
  • Author(s): 鈴木利治、後藤直也、林理沙、羽田沙緒里、山本融
  • Organizer: 第38回日本認知症学会学術集会
• [Presentation] An exception to contralateral dominance of cerebral cortex - from abstract to concrete - (2019)
  • Author(s): Yoshikazu Isomura
  • Organizer: Dynamic Brain Forum (DBF) 1, in The 7th International Congress on Cognitive Neurodynamics (ICCN2019) (Universita di Sassari, Alghero, Italy)
  • Int'l Joint Research / Invited
• [Presentation] Analysis of the effect of IL17A increase on neurodevelopment in RORgt-overexpression transgenic mice. (2019)
  • Author(s): Saki Tome, Rei Nagata, Tetsuya Sasaki, Yosuke Takei.
  • Organizer: 第42回日本神経科学大会・第62回日本神経化学会大会 合同大会
• [Presentation] Analysis of the molecular mechanism of metabolism and tumorigenesis through the loss of tumor suppressor gene NDRG2 (2019)
  • Author(s): Tomonaga Ichikawa, Shingo Nakahata, Mitsuru Futakuchi, Kazuhiro Morishita
  • Organizer: 第78回日本癌学会
• [Presentation] Analysis of the regulatory mechanism underlying brain tumor-initiating cell proliferation by MIF (2019)
  • Author(s): Ohta S, Morimoto Y, Tokumitsu A, Sone T, Sakamoto A, Toda M, Kawakami Y, Okano H
  • Organizer: Neuro2019
• [Presentation] Aplysiatoxin/oscillatoxin類の網羅的合成研究 (2019)
  • Author(s): 西川俊夫
  • Organizer: 新学術領域研究「反応集積化が導く中分子戦略高次生物機能分子の創製」第8回公開成果報告会
• [Presentation] Arc deficiency causes impairment in memory precision and cognitive switching (2019)
  • Author(s): 奥野 浩行
  • Organizer: 第42回日本神経科学学会大会
  • Invited
• [Presentation] Arc/Arg3. 1-driven regulation of activity-dependent AMPA receptor dynamics at active and inactive synapses (2019)
  • Author(s): Haruhiko Bito, Yuichiro Ishii, Hajime Fujii, Takashi Hayashi, Michiko Okamura, Yayoi Kondo, Manabu Abe, Kenji Sakimura, Hiroyuki Okuno
  • Organizer: Neuro2019(第42回日本神経科学大会・第62回日本神経化学会大会)
  • Invited
• [Presentation] Artificial assembly lines for divergent synthesis of natural products and their variants (2019)
  • Author(s): Hiroki Oguri
  • Organizer: The 27th French-Japanese Symposium on Medicinal and Fine Chemistry
  • Int'l Joint Research / Invited
• [Presentation] Astrocytes-mediated synapse remodeling and neuropathic pain. (2019)
  • Author(s): Koizumi, S
  • Organizer: 8th Asian Pain Symposium
  • Int'l Joint Research / Invited
• [Presentation] Astrocytic GPCR Activation in Behaving and Stroke Mice (2019)
  • Author(s): Hajime Hirase
  • Organizer: Gordon conference : Glial Biology
  • Int'l Joint Research / Invited
• [Presentation] Attempt to identify body structure generating a balloon-like rhythmic movement in the green brittle star (2019)
  • Author(s): D. Wakita and H. Aonuma
  • Organizer: 1st Symposium on Invertebrate Neuroscience
  • Int'l Joint Research
• [Presentation] Attempts to visualize neuronal activity by striatal cell type during various learning phases of stimulus discrimination. (2019)
  • Author(s): Iguchi, Y., & Kobayashi, K.
  • Organizer: 新学術領域研究「人工知能と脳科学」第7回領域会議
• [Presentation] Bi-direcional network remodeling by reactive astrocytes (2019)
  • Author(s): Koizumi, S.
  • Organizer: The 10th IBRO World Congress of Neuroscience
  • Int'l Joint Research / Invited
• [Presentation] Brain Magnetic Resonance Imaging Abnormalities Associated with Vigabatrin : Two Cases of infantile Spasm. (2019)
  • Author(s): Fujita T, Ihara Y, Yamaguchi H, Hayashi H, Ishii A, Ideguchi H, Inoue T, Yasumoto S, Hirose S.
  • Organizer: The 20th annual meeting of infantile seizure society
  • Int'l Joint Research
• [Presentation] Ca2+ イメージングによる記憶情報の脳内表現様式の観察. (2019)
  • Author(s): 大川 宜昭, 小山内 実, 井ノ口 馨
  • Organizer: 2019年度先端モデル動物支援プラットフォーム 成果発表会
• [Presentation] Cancer drug screening based on refractoriness of cancer cell reprogramming (2019)
  • Author(s): 伊藤謙治、山田泰広
  • Organizer: 第92回日本生化学会
• [Presentation] Cancer treatments targeting mitochondrial enzymes of one-carbon metabolism (2019)
  • Author(s): 西村建徳、Chen Xiaoxi、Lee Jin、曽我朋義、東條有伸、後藤典子
  • Organizer: 第78回日本癌学会学術総会
• [Presentation] Capturing and identification of MR1-binding molecules using unfolded MR1 protein. (2019)
  • Author(s): C. Motozono, HS. Ismanto, K. Shibata, and S. Yamasaki.
  • Organizer: The 48th Annual Meeting of the Japanese Society for Immunology
• [Presentation] CDX1 regulates stemness and proliferation of neuroblastoma by MYC pathway modulation (2019)
  • Author(s): Hisanori Takenobu, Miki Ohira, Ryuichi Sugino, Koji Chikaraishi, Ryu Okada, Kyosuke Mukae, Masayuki Haruta, Takehiko Kamijo, 他
  • Organizer: The 61st Annual Meeting of the Japanese Society of Pediatric Hematology/Oncology
• [Presentation] Cdy12 is a chromodomain protein involved in pluripotency of stem cells (2019)
  • Author(s): 服部奈緒子、木村佳那、飯田直子、今井俊夫、小泉美帆、本田浩章、牛島俊和
  • Organizer: Post-A3 Meeting
  • Int'l Joint Research
• [Presentation] Central neural mechanisms to defend life from environmental stressors (2019)
  • Author(s): Nakamura, K.
  • Organizer: Visitng Fellows Lecture of the Institute of Advanced Studies at University of Bologna
  • Int'l Joint Research / Invited
• [Presentation] Changes of stem cell related phenotypes under inhibition of enzymes of One-carbon metabolism (2019)
  • Author(s): 西村建徳、曽我朋義、東條有伸、後藤典子
  • Organizer: 第7回がんと代謝研究会
• [Presentation] Characteristics of subjective visual vertical in patients with unilateral spatial neglect (2019)
  • Author(s): Kimihiko Mori, Kae Nakamura, Shingo Hashimoto, Masanori Wakida, Kimitaka Hase
  • Organizer: The 42nd annual meeting of the Japan Neuroscience Society
• [Presentation] Characterization of Luminal High-Osteolytic Breast Cancer Cell Lines (2019)
  • Author(s): Yuxuan Han, Jun Nakayama, Yusuke Hayashi, Seongmoon Jeong, Mitsuru Futakuchi, Emi Ito, Shinya Watanabe, Kentaro Semba
  • Organizer: 2019年度「先端モデル動物支援」成果発表会
• [Presentation] Chemo-enzymatic total synthesis of tetrahydroisoquinoline alkaloids exhibiting potent DNA alkylating ability (2019)
  • Author(s): Ryo Tanifuji
  • Organizer: The 27th French-Japanese Symposium on Medicinal and Fine Chemistry
  • Int'l Joint Research
• [Presentation] Chemo-enzymatic total synthesis of tetrahydroisoquinoline alkaloids exhibiting potent DNA alkylating ability (2019)
  • Author(s): Ryo Tanifuji
  • Organizer: The 27th International Society of Heterocyclic Chemistry Congress
  • Int'l Joint Research
• [Presentation] Chemogenetic inhibition of ventral tegmental area dopamine neurons reveals multidimensional roles in motivated behavior reinforced by natural reward. (2019)
  • Author(s): Iguchi, Y., Kato, S., Nishizawa, K., & Kobayashi, K.
  • Organizer: The 42th Annual Meeting of the Japan Neuroscience Society (Neuro2019)
• [Presentation] Clarification of connectivity between cerebellum and prefrontal cortex (2019)
  • Author(s): 石田綾
  • Organizer: 新学術領域「脳情報動態」領域会議
• [Presentation] Climbing fiber synapse elimination in aldolase C-positive Purkinje cells is delayed compared to aldolase C-positive Purkinje cells and requires phospholipase C beta3 in the developmental cerebellum (2019)
  • Author(s): Takaki Watanabe, Yurie Rai, Honoka Suzuki, Tsubasa Akamatsu, Naofumi Uesaka, Masanobu Kano
  • Organizer: NEURO2019
  • Int'l Joint Research
• [Presentation] CNV in silver nanoparticle-primed hyperactive rats (2019)
  • Author(s): Masami Ishido
  • Organizer: Eurotox 2019
• [Presentation] CNV in silver nanoparticle-primed hyperactive rats (2019)
  • Author(s): Masami Ishido
  • Organizer: 第42回日本神経科学会
• [Presentation] CNV in silver nanoparticlc-primed hyperactive rats (2019)
  • Author(s): Masami Ishido
  • Organizer: 第92回日本生化学会
• [Presentation] Combined representation of emotional arousal and decision signals in primate dorsal raphe nuclcus. (2019)
  • Author(s): Masaharu Yasuda, Yasumasa Ueda, Kae Nakamura
  • Organizer: The 42nd annual meeting of the Japan Neuroscience Society
• [Presentation] Combined representation of emotional salience and decision signals in primate dorsal raphe nucleus. (2019)
  • Author(s): M. Yasuda., Y. Ueda., K. Nakamura.
  • Organizer: Society for Neuroscience
  • Int'l Joint Research
• [Presentation] Compartmentalized input-output organization of cerebellar Lugaro cells. as revealed using knockin-mediated yellow cameleon reporter mice (2019)
  • Author(s): Taisuke Miyazaki, Miwako Yamasaki, Kenji F. Tanaka, Masahiko Watanabe
  • Organizer: 第42回日本神経科学学会
• [Presentation] Comprehensive analysis of secondary mutation as resistance mechanism to seven MET-TKIs for MET exon 14 skipping in vitro (2019)
  • Author(s): 藤野智大
  • Organizer: 第20回世界肺癌学会
  • Int'l Joint Research
• [Presentation] Concise and divergent access to alkaloidal scaffolds by integrating organic and biogenetic synthesis (2019)
  • Author(s): Hiroki Oguri
  • Organizer: The Fourth A3 Roundtable Meeting on Chemical Probe Research Hub
  • Int'l Joint Research / Invited
• [Presentation] Concise Synthesis of Natural Products and their Variants : a Chemoenzymatic and an Element Implantation Approach (2019)
  • Author(s): Hiroki Oguri
  • Organizer: The14th International Conference on Cutting-Edge Organic Chemistry in Asia
  • Int'l Joint Research / Invited
• [Presentation] Constructive understanding of abnormality of primate-specific synaptic reorganization in psychiatric disorders. (2019)
  • Author(s): Tetsuya Sasaki
  • Organizer: The 2nd Meeting of Scientific Research on Innovative Areas “Multiscale Brain”
  • Invited
• [Presentation] Critical regulation of metabolites for hematopoietic homeostasis and leukemogenesis (2019)
  • Author(s): 平尾 敦
  • Organizer: 第42回日本分子生物学会年会
  • Invited
• [Presentation] Critical role of nutrient signals in hematopoietic stemness and malignancy (2019)
  • Author(s): 平尾 敦
  • Organizer: 第92回日本生化学会大会
  • Int'l Joint Research / Invited
• [Presentation] Critical roles of gut microbiota in self-renewal of hematopoietic stem cells and leukemogenesis (2019)
  • Author(s): 平尾 敦
  • Organizer: 2nd Japan-German symposium
  • Int'l Joint Research / Invited
• [Presentation] Crossroads of telomere biology and cancer drug discovery (2019)
  • Author(s): Seimiya H
  • Organizer: 第78回日本癌学会学術総会
  • Invited
• [Presentation] Decreases in chain lengths and level of myelin sphingolipids are associated with hypomyelination and deficient motor coordination in mice lacking fatty acid elongase ELOVL1 (2019)
  • Author(s): Sassa T, Isokawa M, Kihara A
  • Organizer: 第42回日本神経科学大会/第62回日本神経化学会大会(NEURO2019)
  • Int'l Joint Research
• [Presentation] Design and Modular De Novo Synthesis of 6-Aza-artemisinins (2019)
  • Author(s): Norihito Takahashi
  • Organizer: The 27th French-Japanese Symposium on Medicinal and Fine Chemistry
  • Int'l Joint Research
• [Presentation] Development and application of the multimodal ultra-thin endoscope for analyzing neuronal circuits in the deep brain region. (2019)
  • Author(s): Osanai, M., Ohkawa, N., Iguchi, Y., Yokose, J., Nakayama, S., Inokuchi, K., Kobayashi, K., Haga, Y., & Mushiake, H.
  • Organizer: Neural Oscillation Conference 2019
  • Int'l Joint Research / Invited
• [Presentation] Development and application of the multimodal ultra-thin endoscope for analyzing neuronal circuits in the deep brain region. (2019)
  • Author(s): Osanai M, Ohkawa N, Iguchi Y, Yokose J, Nakayama S, Inokuchi K, Kobayashi K, Haga Y, Mushiake H.
  • Organizer: 次世代脳プロジェクト冬のシンポジウム
• [Presentation] Development of 2DE-CETSA as a novel platform by 2- dimensional electrophoresis based-proteomic analysis for target identification of small molecules (2019)
  • Author(s): Ikuko Nagasawa, Makoto Muroi, Ayumi Ikeno, Naoko Ogawa, Makoto Kawatani, Hiroyuki Osada
  • Organizer: The lst International Symposium on Chemical Communication (ISCC2019)
  • Int'l Joint Research
• [Presentation] Development of divergent synthetic processes to explore frontiers in natural product chemistry (2019)
  • Author(s): Hiroki Oguri
  • Organizer: Let's Leap! Challenges in Organic Chemistry
  • Invited
• [Presentation] Development of light-up-type probes for detection of G-quadruplex (2019)
  • Author(s): Yue Ma, Yuki Wakabayashi, Ryota Saito, Kazuo Nagasawa
  • Organizer: The 46th International Symposium on Nucleic Acids Chemistry
  • Int'l Joint Research
• [Presentation] Development of neuroblastoma model from iPSC-based neural crest cells (2019)
  • Author(s): Kyosuke Mukae, Hisanori Takenobu, Junya Toguchida, Kenji Osafune, Tatsutoshi Nakahata, Takehiko Kamijo
  • Organizer: 第78回日本癌学会学術総会
• [Presentation] Development of neuroblastoma model from iPSC-based neural crest cells (2019)
  • Author(s): Kyosuke Mukae, Ryuichi Suginol, Miki Ohira, Masayuki Haruta, Junya Toguchida, Kenji Osafune, Tatsutoshi Nakahata, Takehiko Kamijo, 他
  • Organizer: The 78th Annual Meetings of the Japanese Cancer Association
• [Presentation] Developmental defects of serotonergic neurons induced by maternal immune activation. (2019)
  • Author(s): Jinmin Li, Fumihiro Shutoh, Tetsuya Sasaki, Yosuke Takei.
  • Organizer: Tsukuba Conference
  • Int'l Joint Research
• [Presentation] Differential modulation of striatal medium spiny neuron via the cortico-striatal stimulation. (2019)
  • Author(s): Inagaki R, Sasagawa M, Osanai M
  • Organizer: 第42回日本神経科学大会
• [Presentation] Dipeptidyl peptidase ⅢによるⅡ型糖尿病モデルマウスの心・腎臓機能低下抑制効果 (2019)
  • Author(s): 米野雅大、清水昭男、Xiaoling Pang、扇田久和
  • Organizer: 先端モデル動物支援プラットフォーム若手支援技術講習会
• [Presentation] Distinct roles of canonical and non-canonical synaptogenic signaling of neuroligin 3 (2019)
  • Author(s): Yoshida T, Imai-Tabata A, Yamagata A, Izumi H, Shiroshima T, Kim J, Fukata M, Takao K, Mori H, S. Fukai
  • Organizer: NEURO2019
  • Int'l Joint Research
• [Presentation] DNAアルキル化能を有するテトラヒドロイソキノリンアルカロイド群の化学-酵素ハイブリッド合成 (2019)
  • Author(s): 谷藤 涼
  • Organizer: 核酸化学若手フォーラム2019
  • Invited
• [Presentation] DNA複製の正と負の制御に関わるグアニン4重鎖構造(In search of a universal mode of DNA replication) (2019)
  • Author(s): 正井 久雄、加納 豊、田中 卓、吉沢 直子、伊藤 さゆり、森山 賢治、加藤 宏幸、井口 智弘、松本 清治、Zhiying You、深津 理乃、覺正 直子、鷺 朋子、小林 駿介、楊 基駿、堀 かりん、髙沢 佳芳、富樫 育子、上野 勝、長澤 和夫、Yue Ma
  • Organizer: 第42回 日本分子生物学会年会 ワークショップ『染色体DNA複製研究のニューフロンティア』
  • Invited
• [Presentation] Dual inhibition of distinct metabolic features targets osteosarcoma stem cells (2019)
  • Author(s): Kishi S, Honoki K, Tsukamoto S, Fujii H, Kondo Y, Tanaka Y, Kuniyasu H
  • Organizer: American Association for Cancer Research Annual Meeting 2019
  • Int'l Joint Research
• [Presentation] Dysfunction of Tsukushi leads to hydrocephalus by altering neurogenesis in the subventricular zone. (2019)
  • Author(s): 伊藤尚文, Shah Adil Ishtiyaq Ahmad, Mohammad Badrul Anam, 太田訓正
  • Organizer: Joint Symposium with Molecular Neurodegeneration
• [Presentation] Enhanced retrieval of learned emotional memory by chemogenetic activation of locus coeruleus noradrenergic neurons. (2019)
  • Author(s): Iguchi, Y.
  • Organizer: The 19th Annual Meeting of JSNP
  • Invited
• [Presentation] Enhanced β- and β' -cleavages of APP in Alcadein α knockout mouse brain. (2019)
  • Author(s): Toshiharu Suzuki, Naoya Goto, Haruka Saito, Saori Hata, Tohru Yamamoto
  • Organizer: Alzheimer's Association International Conference 2019
  • Int'l Joint Research
• [Presentation] Epigenetic modifier regulates accurate transcription on the bivalent histone marked angiogenic genes in endothelium (2019)
  • Author(s): 南 敬
  • Organizer: Cell Symposia
  • Int'l Joint Research
• [Presentation] Epithelial barrier homeostasis by cell competition. (2019)
  • Author(s): Tetsuhisa Otani and Mikio Furuse
  • Organizer: 52nd Annual meeting of the Japanese Society of Developmental Biologists
• [Presentation] Epithelial membrane protein 1はRaclを活性化してがん細胞の遊走を促進させがんの浸潤・転移を促進する (2019)
  • Author(s): 清水昭男、Mohammad Khusni Bin Ahmat Amin、佐藤朗、扇田久和
  • Organizer: 日本生化学会
• [Presentation] Establishment and Characterization of Luminal High-Osteolytic Breast Cancer Cell Lines Using Intra-Caudal Arterial Injection (2019)
  • Author(s): Yuxuan Han, Jun Nakayama, Mitsuru Futakuchi, Emi Ito, Shinya Watanabe, Kentaro Semba
  • Organizer: 第78回日本癌学会学術総会
• [Presentation] Establishment of a mouse model for mutant CALR myeloproliferative neoplasms (2019)
  • Author(s): Misa Imai, Yasutaka Fukuda, Teppei Taguchi, Kyohei Misawa
  • Organizer: 第81回日本血液学会学術集会
• [Presentation] Expression mapping, quantification, and complex formation of GluD1 and GluD2 glutamate receptors in adult mouse brain. (2019)
  • Author(s): Kohtarou Konno, Chihiro Nakamoto, Kenji Sakimura, Masanobu Kano, Masahiko Watanabe.
  • Organizer: IBRO2019
  • Int'l Joint Research
• [Presentation] Ferroptosis in cancer research : biological significance of ferroptosis in health and disease. (2019)
  • Author(s): Toyokuni S
  • Organizer: 10th International Conference on Nutrition and Physical Activity in Aging, Obesity and Cancer (NAPA2019)
  • Int'l Joint Research / Invited
• [Presentation] Forster resonance energy transfer-assisted photoactivation of CRY2 for the optical control of protein interactions by two-photon excitation microscopy (2019)
  • Author(s): Tomoaki Kinjo, Kenta Terai, Shoichiro Horita, Norimichi Nomura, Kenta Sumiyama, Kaori Togashi, So Iwata, Michiyuki Matsuda
  • Organizer: Next Generation Protein Therapeutics & Bioconjugates Summit
  • Int'l Joint Research
• [Presentation] Functional assay using microelectrode array system (MEA) for neurons derived from iPSCs from a patient with Dravet syndrome. (2019)
  • Author(s): 田中泰圭、石川充、日暮憲道、岡野栄之、廣瀬伸一
  • Organizer: 第53回日本てんかん学会学術集会
• [Presentation] Functional defect of polycomb repressive complex 2 in hematopoietic stem cells with aging (2019)
  • Author(s): Naoya Itokawa, Motohiko Oshima, Yaeko Nakajima, Satoshi Yamazaki, and Atsushi Iwama
  • Organizer: 48th Annual Scientific Meeting of International Society for Experimental Hematology
  • Int'l Joint Research
• [Presentation] F環部改変ラメラリンN誘導体合成法の開発 (2019)
  • Author(s): 小田亮平, 辻圭弥, 福田勉, 小野寺玄, 木村正成
  • Organizer: 第56回化学関連支部合同九州大会
• [Presentation] GAD67ノックアウトラットの認知機能障害 (2019)
  • Author(s): 藤原和之、柿崎利和、Jiang Weiru、宮田茂雄、須藤貴史、齋藤繁、山田一夫、一谷幸男、梶田裕貴、大城朝一、虫明元、渡邊雅彦、宮坂佳樹、真下知士、安田浩樹、柳川右千夫
  • Organizer: 第41回日本生物学的精神医学会
• [Presentation] Generation of the conditional-rescue transgenic mice that can regulate rescue-gene expression in the null mutant mice background. (2019)
  • Author(s): 櫻井 瑛輝, 伏見 尚晃, 花岡 和則, 渡辺 大介
  • Organizer: 日本分子生物学会
• [Presentation] Genetic dissection of the structural and functional organization of tight junctions. (2019)
  • Author(s): Tetsuhisa Otani, Thanh Phuong Nguyen, and Mikio Furuse
  • Organizer: Gordon Research Conference on Cell Contact and Adhesion
  • Int'l Joint Research
• [Presentation] Glial cells as a therapeutic target for anti-depressants. (2019)
  • Author(s): Koizumi, S.
  • Organizer: 第6回アジア神経精神薬理学会
  • Int'l Joint Research
• [Presentation] Glial phagocytic clearance in health and disease. (2019)
  • Author(s): Koizumi, S
  • Organizer: ISN-ASNMeeting
  • Int'l Joint Research / Invited
• [Presentation] Heterogeneity of astrocytes in synapse remodeling (2019)
  • Author(s): Koizmi, S.
  • Organizer: NEURO2019
• [Presentation] Homeostasis in NFAT-DSCR-1 signaling is critical for initial epigenetic conversion and the following proper vessel formation (2019)
  • Author(s): 南 敬
  • Organizer: Joint Angiogenesis Meeting
  • Int'l Joint Research / Invited
• [Presentation] HTLV-1感染におけるモノクロナリティと挿入部位を同定する新しい検査法 (2019)
  • Author(s): 長谷川寛雄(発表代表者・責任発表者)、斎藤益満(研究分担者)
  • Organizer: 第78回日本癌学会学術総会
• [Presentation] Human neurodegenerative disease-like phenotypes induced by acquired expression of mutant MFN2 in mice. (2019)
  • Author(s): Kaori Ishikawa, Satoshi Yamamoto, Satoko Hattori, Naoya Nishimura, Haruna Tani, Hirokazu Matsumoto, Tsuyoshi Miyakawa, and Kazuto Nakada
  • Organizer: The 16th Conference of Asian Society for Mitochondrial Research and Medicine [ASMRM] and The 19th Conference of Japan Society for Mitochondrial Research and Medicine [J-mit]
  • Int'l Joint Research
• [Presentation] Hypoxia induced factor 1α regulates Schwann cell differentiation in peripheral nerves. (2019)
  • Author(s): Shuji Wakatsuki, Yuka Ujiie, Toshiyuki Araki
  • Organizer: 24th Annual Meeting of Japan Glia
• [Presentation] Identification of adult stem cells by the multicolor lineage tracing and the sc RNAseq methods (2019)
  • Author(s): 上野博夫
  • Organizer: 第78回日本癌学会学術総会
  • Invited
• [Presentation] Identification of responsible genes for Stmm loci conferring resistance to chemically induced skin tumors (2019)
  • Author(s): Kazuhiro Okumura, Megumi Saito, Eriko Isogai, Yuichi Wakabayashi
  • Organizer: 第78回日本癌学会学術総会
  • Invited
• [Presentation] IGF-IRシグナル阻害を介したAhR活性化の抑制 (2019)
  • Author(s): 冨田俊維、遠藤治、稲葉一穂、関本征史
  • Organizer: 第46回日本毒性学会学術年会
• [Presentation] Imaging voltage in dendritic spines with genetically encoded indicators. (2019)
  • Author(s): Masayuki Sakamoto
  • Organizer: IBRO 2019
  • Int'l Joint Research
• [Presentation] Immunological profiles of Dravet syndrome. (2019)
  • Author(s): 倉橋宏和、沼本真吾、奥村彰久、石井敦士、廣瀬伸一
  • Organizer: 第53回日本てんかん学会学術集会
• [Presentation] Innately induced palatable feeding by dietary imbalance of essential fatty acids. (2019)
  • Author(s): Sakayori, N., Higuchi, O., Fukabori, R., Iguchi, Y., Setogawa, S., Eitsuka, T., Miyazawa, T., & Kobayashi, K.
  • Organizer: The 42th Annual Meeting of the Japan Neuroscience Society (Neuro2019)
• [Presentation] Innately induced palatable feeding by dietary imbalance of essential fatty acids. (2019)
  • Author(s): Nobuyuki Sakayori, Oki Higuchi, Ryoji Fukabori, Yoshio Iguchi, Susumu Setogawa, Takahiro Eitsuka, Teruo Miyazawa, Kazuto Kobayashi
  • Organizer: NEURO2019
• [Presentation] Inverse synaptic tagging of Arc and cognitive refinement processes (2019)
  • Author(s): Hiroyuki Okuno
  • Organizer: 14th International Congress of the Polish Neuroscience Society
  • Int'l Joint Research / Invited
• [Presentation] Involvement of low contrast-preferring neurons in an orientation discrimination task in rat primary visual cortex. (2019)
  • Author(s): Kimura R, Yoshimura Y
  • Organizer: The 9th Okazaki-Tuebingen-Beijing Joint Symposium
  • Int'l Joint Research / Invited
• [Presentation] Involvement of the ventral tegmental area-nucleus accumbens dopaminergic systems in antidepressant-like action of omega-3 polyunsaturated fatty acid-rich diets (2019)
  • Author(s): Eri Takeuchi, Daisuke Yamada, Akiyoshi Saitoh, Masayuki Itoh, Takashi Hayashi, Mitsuhiko Yamada, Keiji Wada, Masayuki Sekiguchi
  • Organizer: Neuro2019 (第42回日本神経科学大会・第62回日本神経化学会大会)
• [Presentation] Kazuto Kobayashi, Different function of striatal sub-regions during acquisition of the auditory discrimination task (2019)
  • Author(s): 瀬戸川将, 岡内隆, 胡迪, 酒寄信幸, 重田美香, 疋島啓吾, 尾上浩隆, 崔翼龍, 小林和人
  • Organizer: 第42回日本神経科学大会
• [Presentation] KLF4によるプロテアーゼ発現制御機構の解析 (2019)
  • Author(s): 立田咲百合、金井凛、鬼頭昭吉、竹内優斗、阿部真土
  • Organizer: 第12回大阪大学医学系若手フォーラム
• [Presentation] Linear type hexaoxazole as a G-quadruplex ligand for selective anti-parallel topology (2019)
  • Author(s): Shogo Sasaki、Yue Ma, Kazuo Nagasawa
  • Organizer: CISNAC2019 (Commemorative International Symposium of the Japan Society of Nucleic Acids Chemistry)
  • Int'l Joint Research
• [Presentation] Liquid- and solid-like RNA granule formation and its implications for neuronal functions (2019)
  • Author(s): N Shiina
  • Organizer: Frontier Bioorganization Forum 2019
  • Int'l Joint Research / Invited
• [Presentation] Localization of phosphorylated protein GAP-43 (2019)
  • Author(s): Masayasu Okada, Asami Kawasaki, Atsushi Tamada, Kitaura, Makoto Oishi, Kazunobu Sawamoto, Kosei Takeuchi, Fujii Yukihiko, Michihiro Igarashi
  • Organizer: 第42回日本神経科学大会(Neuro2019)
• [Presentation] Long non-coding RNAの解析から明らかとなった新規ポリペプチドワールド (2019)
  • Author(s): 松本 有樹修
  • Organizer: 第37回日本骨代謝学会
  • Invited
• [Presentation] LRBA DUF1088ドメインの自然免疫制御における重要性 (2019)
  • Author(s): 及川大輔、駒倉啓大、福士雅也、入江崇、堀居拓郎、畑田出穂、坂口剛正、徳永文稔
  • Organizer: 第42回日本分子生物学会
• [Presentation] LUBACシグナルソームによる自然免疫応答の選択的制御 (2019)
  • Author(s): 及川大輔、駒倉啓大、阿部貴則、飯尾清誠、小比賀真吾、勝矢健、花田和希、坂本信二、徳永文稔
  • Organizer: 第91回日本生化学会大会
  • Invited
• [Presentation] LUBACによるT細胞受容体シグナル制御に関する細胞・生化学及び数理モデル解析 (2019)
  • Author(s): 及川大輔、畑中尚也、鈴木貴、徳永文稔
  • Organizer: 第14日本臨床ストレス応答学会大会
• [Presentation] LUBACによるT細胞受容体シグナル制御に関する数理モデル解析 (2019)
  • Author(s): 及川大輔、畑中尚也、鈴木貴、徳永文稔
  • Organizer: 数理腫瘍学研究会
  • Invited
• [Presentation] Mathematical modeling of the recruitment of centriole biogenesis regulators to mother centrioles in centriole duplication phase (2019)
  • Author(s): Takanori Nakamura, Noriko Nishizumi-Tokai, Takashi Nakazawa, Tatsuki Mori, Takashi Suzuki, Mutsuhiro Takekawa
  • Organizer: JSPS Core-to-Core Program "Establishing International Research Network of Mathematical Oncology" in Bordeaux
  • Int'l Joint Research / Invited
• [Presentation] MCH neurons impaired memories during REM slecp (2019)
  • Author(s): 山中章弘
  • Organizer: 第11回光操作研究会
  • Invited
• [Presentation] MCH neurons impaired memories during REM sleep. (2019)
  • Author(s): Yamanaka A
  • Organizer: 2019 Chinese Sleep Research Society (CSRS) Annual Academic Conference
  • Int'l Joint Research / Invited
• [Presentation] Measuring Voltage in Dendritic Spines with Genetically Encoded Voltage Indicators. (2019)
  • Author(s): Masayuki Sakamoto, Taekung Kwon, Darcy S. Peterka, Rafael Yuste
  • Organizer: 第42回分子生物学学会年会
  • Int'l Joint Research
• [Presentation] Mechanism underlying generating ultra fast movement in insect (2019)
  • Author(s): 青沼仁志
  • Organizer: 9th International Congress on Industrial and Applied Mathematics (ICIAM 2019)
  • Int'l Joint Research
• [Presentation] Metabolic vulnerability in senescent cells (2019)
  • Author(s): 中西 真、城村 由和
  • Organizer: 第42回日本分子生物学会年会
  • Invited
• [Presentation] Mixed representation of sensory and motor signals in primate primary somatosensory cortex. (2019)
  • Author(s): 望月圭、中陦克己、稲瀬正彦、村田哲
  • Organizer: Neuro2019
  • Int'l Joint Research
• [Presentation] Molecular genetic analysis of the role of interleukin 17A in CNS. (2019)
  • Author(s): Saki Tome, Tetsuya Sasaki, Yosuke Takei.
  • Organizer: Tsukuba Conference.
  • Int'l Joint Research
• [Presentation] MSMマウスにおける腫瘍低抗性遺伝子の探索 (2019)
  • Author(s): 奥村和弘
  • Organizer: 第32回モロシヌス研究会
• [Presentation] Multi-organ metastasis誘導遺伝子HNF1Bの同定と機能解析 (2019)
  • Author(s): 中山淳, 二口充, 仙波憲太郎
  • Organizer: 第28回日本がん転移学会学術集会・総会
• [Presentation] Network remodeling by astrocytic synaptogenesis and phagocytosis. (2019)
  • Author(s): Koizumi, S
  • Organizer: ?? European Meeting on Glial Cells in Health and Disease
  • Int'l Joint Research
• [Presentation] Neural mechanisms of acute stress-induced enhancement of cocaine craving (2019)
  • Author(s): Kaneda K
  • Organizer: AsCNP2019 (6th Congress of Asian College of Neuropsychopharmacology)
  • Int'l Joint Research / Invited
• [Presentation] Neural mechanisms underlying stress-induced enhancement of cocaine craving (2019)
  • Author(s): 金田 勝幸
  • Organizer: NEURO2019(第42回日本神経科学大会・第62回日本神経化学会大会)
• [Presentation] Neurobiology and biomechanics of ultra fast movement in the trap-jaw ant (2019)
  • Author(s): 青沼仁志
  • Organizer: The 3rd International Symposium on Swarm Behavior and Bio-Inspired Robotics (SWARM 2019)
  • Int'l Joint Research / Invited
• [Presentation] Neuropathy Target Esteraseと神経機能-遺伝子操作マウスを用いた解析 (2019)
  • Author(s): 木村穰、阿部如子、本杉奈美、坂部貢、加藤明
  • Organizer: 第28回日本臨床環境医学会学術集会
• [Presentation] Neuropathy Target Esterase遺伝子操作マウスの機能解析-神経機能解析を中心に (2019)
  • Author(s): 木村穰、阿部如子、本杉奈美、坂部貢、加藤明
  • Organizer: 第42回日本分子生物学会年会
• [Presentation] NFYA regulates the acquisition of drug resistance in breast cancer (2019)
  • Author(s): Nobuhiro Okada, Hayato Muranaka, Chiaki Takahashi
  • Organizer: 第78回日本癌学会学術総会
• [Presentation] NFYAによる糖新生促進が引き起こす腫瘍抑制効果の検討 (2019)
  • Author(s): 辻本剛己、高橋智聡、岡田宣宏
  • Organizer: 2019年度文部科学省新学術領域研究学術研究支援基盤形成【先端モデル動物支援プラットフォーム】若手支援技術講習会
• [Presentation] Novel TMEM168 gene mutation in Brugada syndrome impairs sodium channel function via the Nav1.5 degradation. (2019)
  • Author(s): Hisakazu Ogita、Dimitar P. Zankov、Akio Shimizu
  • Organizer: American Heart Association
  • Int'l Joint Research
• [Presentation] NOX-dependent ZNRF1 activation controls neuronal polarity and axon specification. (2019)
  • Author(s): Shuji Wakatsuki
  • Organizer: Keystone Symposia on Molecular and Cellular Biology.
  • Int'l Joint Research
• [Presentation] One carbon metabolism関連遺伝子変異体を用いたDOHaDモデルの開発 (2019)
  • Author(s): 古瀬民生、山田郁子、串田知子、三浦郁生、尾崎藍、永瀬茜、若菜茂晴、田村勝
  • Organizer: NEURO2019
• [Presentation] Optogenetics as a tool to understand regulatory mechanism of sleep and memory by the hypothalamic neurons. (2019)
  • Author(s): Yamanaka A
  • Organizer: IBRO APRC School 2019
  • Int'l Joint Research / Invited
• [Presentation] Orexin and MCH neurons double ablated mice showed severe sleep attack and cataplexy (2019)
  • Author(s): 洪 啓栄
  • Organizer: 先端モデル動物支援プラットフォーム 2019年度若手支援技術講習会
• [Presentation] p53が制御する新規の神経内分泌腫瘍抑制経路の解明 (2019)
  • Author(s): 大木 理恵子
  • Organizer: 第42回日本分子生物学会年会
  • Invited
• [Presentation] p53が制御する新規の神経内分泌腫瘍抑制経路の解明 (2019)
  • Author(s): 大木 理恵子
  • Organizer: 第78回日本癌学会学術総会
  • Invited
• [Presentation] Pathological roles of senometabolites in cardiovascular-metabolic disorders (2019)
  • Author(s): 清水逸平
  • Organizer: ISHR2019
  • Invited
• [Presentation] Peripheral blood CD8+T cell subsets correlated with PD-1 Ab response in melanoma patients by scRNA-seq analysis (2019)
  • Author(s): Ohta S, Matsumoto D, Nagumo H, Fujita T, Takahashi A, Namikawa K, Kitano A, Yamazaki N, Kawakami Y.
  • Organizer: 5th CRI-CIMT-EATI-AACR International cancer immunotherapy conference
  • Int'l Joint Research
• [Presentation] Phenotype characterization of GAD65/GAD67 double mutant rats (2019)
  • Author(s): 姜玮茹、柿崎利和、藤原和之、宮田茂雄、張月、須藤貴史、加藤大樹、齋藤繁、柴崎貢志、石崎泰樹、宮坂佳樹、真下知士、柳川右千夫
  • Organizer: 日本ゲノム編集学会第4回大会
• [Presentation] PHLDA3遺伝子とMEN1遺伝子による膵臓神経内分泌腫瘍抑制機構の解明 (2019)
  • Author(s): 陳 ヨ、大木理恵子
  • Organizer: 第78回日本癌学会学術総会
• [Presentation] piRNA biogenesis and function (2019)
  • Author(s): 塩見美喜子
  • Organizer: EMBO Member's Meeting2019
  • Int'l Joint Research
• [Presentation] piRNA biogenesis and function in Drosophila (2019)
  • Author(s): 塩見美喜子
  • Organizer: The RNA Localization and Local Translation Conferrence
  • Int'l Joint Research / Invited
• [Presentation] piRNA Biogenesis and functions in Drosophila (2019)
  • Author(s): 塩見美喜子
  • Organizer: Cell Symposia Regulatory RNAs
  • Int'l Joint Research / Invited
• [Presentation] piRNA Biogenesis and functions in Drosophila (2019)
  • Author(s): 塩見美喜子
  • Organizer: Keystone Symposia/Small Regulatory RMAs
  • Int'l Joint Research / Invited
• [Presentation] Poly(I : C)による妊娠中母体免疫の活性化方法の差による仔の行動異常の相違 (2019)
  • Author(s): 矢口 立真, 石林 朋子, 二井谷 和平, 向井 沙和子, 江崎 博仁, 出山 諭司, 金田 勝幸
  • Organizer: 日本薬学会北陸支部 第131回例会
• [Presentation] Potent inhibitory effect of vandetanib on methotrexate-induced epithelial-mesenchymal transition (EMT) in alveolar epithelial A549 cells (2019)
  • Author(s): Masashi Kawami, Ryoko Yumoto, Mikihisa Takano
  • Organizer: 2019AAPS PharmSci360
  • Int'l Joint Research
• [Presentation] Programmable Divergent Synthesis of Skeletally Diverse Alkaloidal Scaffolds (2019)
  • Author(s): Hiroki Oguri
  • Organizer: The 19th Tateshina Conference on Prganic Chemistry
  • Int'l Joint Research
• [Presentation] Progressive neurodegeneration and abnormal behavior were caused by acquired expression of mutant Mitofusin 2 in neurons. (2019)
  • Author(s): Kaori Ishikawa, Satoshi Yamamoto, Satoko Hattori, Naoya Nishimura, Takayuki Mito, Hirokazu Matsumoto, Tsuyoshi Miyakawa, Kazuto Nakada
  • Organizer: The Cold Spring Harbor Asia conference on Mitochondria and Metabolism in Health and Disease
  • Int'l Joint Research / Invited
• [Presentation] Proof of concept for claudin-2-directed cancer therapy by using a monoclonal antibody that recognizes the extracellular loop domain of claudin-2 (2019)
  • Author(s): Hashimoto Y, Hata T, Tada M, Iida M, Watari A, Okada Y, Doi T, Kuniyasu H, Yagi K, Tachibana K, Kondoh M
  • Organizer: 2019 Controlled Release Society Annual Meeting & Exposition
  • Int'l Joint Research
• [Presentation] Protocadherin 10 delays developmental climbing fiber synapse elimination in a subset of aldolase C-positive Purkinje cells in the cerebellum (2019)
  • Author(s): Takaki Watanabe, Honoka Suzuki, Tsubasa Akamatsu, Kazuto Sakoori, Shutaro Inoue, Manabu Abe, Kenji Sakimura, Naofumi Uesaka, Masanobu Kano
  • Organizer: 次世代脳プロジェクト冬のシンポジウム2019
• [Presentation] Regional specificity of KCNQ2 missense variants causing benign or epileptic encephalopathy phenotype. (2019)
  • Author(s): Ishii A, Goto A, Ihara Y, Hirose S, Ihara Y, Hirose S.
  • Organizer: International Epilepsy Congress
  • Int'l Joint Research
• [Presentation] Regulation of the dynamics of RNA granule condensates and its implications for long-term memory (2019)
  • Author(s): N Shiina
  • Organizer: NIBB-Princeton Joint Symposium
  • Int'l Joint Research / Invited
• [Presentation] REM sleep active MCH neurons are involved in forgetting hippocampus-dependent memories (2019)
  • Author(s): Yamanaka A
  • Organizer: 6th Congress of Asian College of Neuropsychopharmacology
• [Presentation] REM sleep active MCH neurons are involved in forgetting hippocampus-dependent memories. (2019)
  • Author(s): Yamanaka A, Izawa S
  • Organizer: IBRO 2019
  • Int'l Joint Research / Invited
• [Presentation] Representation of social and emotional information in primate amygdala (2019)
  • Author(s): Koji Kuraoka, Kae Nakamura
  • Organizer: The 42nd annual meeting of the Japan Neuroscience Society
• [Presentation] RNA顆粒足場タンパク質による液相・固相RNA顆粒の形成及びその長期記憶との関連 (2019)
  • Author(s): 椎名伸之
  • Organizer: 第42回日本分子生物学会年会
  • Invited
• [Presentation] Robol confers laminar-specific apical dendritiogenesis and connectivity in the neocortex. (2019)
  • Author(s): Yuko Gonda, Tetsuya Sasaki, William Andrews, John Parnavelas, Alain Chedotal, Tatsunori Seki, Carina Hanashima.
  • Organizer: 20th TMIMS International Symposium 「Principles of Neocortical Development and Evolution」
  • Int'l Joint Research
• [Presentation] ROCK阻害剤は化学療法低抗性の骨肉腫細胞において脂肪細胞への終末分化を阻害し腫瘍形成性を抑制する (2019)
  • Author(s): 信末博行
  • Organizer: 第78回日本癌学会学術総会
  • Int'l Joint Research / Invited
• [Presentation] Role of cellular senescence in aging and age-related disorders (2019)
  • Author(s): Yoshikazu Johmura
  • Organizer: 1st International Symposium on Inflammation Cellular Sociology
  • Int'l Joint Research / Invited
• [Presentation] Role of Derlin-1 in the adult hippocampal neurogenesis (2019)
  • Author(s): Naoya Murao, Hideki Nishitoh
  • Organizer: NEURO2019
• [Presentation] Role of ferroptosis in carcinogenesis and tumor biology. (2019)
  • Author(s): Toyokuni S, Jiang L. Li Z, Ito F and Akatsuka S.
  • Organizer: The 9th Biennial joing meeting of the Society for Free Radical Research Autralasia and Japan
  • Int'l Joint Research
• [Presentation] Role of ferroptosis in carcinogenesis and tumor biology. SY29 : Antioxidants and redox regulation. (2019)
  • Author(s): Toyokuni S
  • Organizer: The 7th Interenational Conference on Food Factors
  • Int'l Joint Research / Invited
• [Presentation] Role of MCH neurons in the regulation of metabolism, sleep/wakefulness and memory. (2019)
  • Author(s): Yamanaka A
  • Organizer: 国際シンポジウム「Sensing food/nutrient/environment toward integrative metabolic regulation」
  • Int'l Joint Research / Invited
• [Presentation] Role of REM sleep on memory. (2019)
  • Author(s): Yamanaka A
  • Organizer: Cold Spring Harbor Asia Neurobiology of Behavior & Neuropsychiatric Disorders
  • Int'l Joint Research / Invited
• [Presentation] Roles of rat glutamate decarboxylase isoforms in the perinatal period (2019)
  • Author(s): 姜玮茹、柿崎利和、藤原和之、宮田茂雄、張月、須藤貴史、加藤大樹、齋藤繁、柴崎貢志、石崎泰樹、宮坂佳樹、真下知士、柳川右千夫
  • Organizer: 第42回日本神経科学大会 第62回日本神経化学会大会
• [Presentation] Roles of rat glutamate decarboxylase isoforms in the perinatal period -GABA and developing brain, implications for anesthesia (2019)
  • Author(s): 姜玮茹
  • Organizer: 日本臨床麻酔学会 第39回大会
  • Invited
• [Presentation] Screening and characterization of novel LUBAC inhibitors, HOIPINs. (2019)
  • Author(s): Oikawa D, Katsuya K, Hanada K, Sugawara K, Tsuruta D, Sakamoto S, Tokuanga F.
  • Organizer: Cold Spring Harbor meeting : Ubiquitins, Autophagy & Disease.
  • Int'l Joint Research
• [Presentation] Segregated and overlapped processing of social and reward information in primate amygdala. (2019)
  • Author(s): K. Kuraoka. K. Nakamura.
  • Organizer: Society for Neuroscience
  • Int'l Joint Research
• [Presentation] Selective turnover of p62-bodies through autophagy (2019)
  • Author(s): Masaaki Komatsu
  • Organizer: 9th International Symposium on Autophagy
  • Int'l Joint Research / Invited
• [Presentation] Selective turnover of p62-bodies through autophagy (2019)
  • Author(s): Masaaki Komatsu
  • Organizer: Seoul National University Bioscience Symposium
  • Int'l Joint Research / Invited
• [Presentation] Selective turnover of p62-liquid droplets through autophagy : The molecular mechanism and physiological significance (2019)
  • Author(s): Masaaki Komatsu
  • Organizer: Asian Pacific Prion Symposium 2019
  • Int'l Joint Research / Invited
• [Presentation] Significance of ferroptosis in cancer research. Symposium 4 : Cancer and redox biology. (2019)
  • Author(s): Toyokuni S
  • Organizer: The 9th Biennial Meeting of Society for Free Radical Research -Asia (SFRR-Asia)? The Era for Redox Research
  • Int'l Joint Research / Invited
• [Presentation] Slit2 is preferentially expressed in the higher-order association area of primate cortex. (2019)
  • Author(s): Tetsuya Sasaki, Yusuke Komatsu, Tetsuo Yamamori.
  • Organizer: Neuroscience 2019
  • Int'l Joint Research
• [Presentation] SLIT2 is preferentially expressed in the the higher-order association areas in primates. (2019)
  • Author(s): Tetsuya Sasaki, Yusuke Komatsu, Yosuke Takei, Tetsuo Yamaori.
  • Organizer: 第42回日本神経科学大会・第62回日本神経化学会大会 合同大会
• [Presentation] Suppressive effect of vandetanib on drug-induced epithelial-mesenchymal transition via inhibition of p53 pathway (2019)
  • Author(s): Masashi Kawami, Ryoko Yumoto, Mikihisa Takano
  • Organizer: 日本薬物動態学会第34回年会
• [Presentation] Synthesis and Biological activities of Aplysiatoxin/Oscillatoxin Marine Natural Products. (2019)
  • Author(s): Toshio Nishikawa
  • Organizer: Marine Biotechnology Conference 2019
  • Int'l Joint Research / Invited
• [Presentation] Synthesis and biological evaluation of oscillatosins marine derived natural products. (2019)
  • Author(s): Toshio Nishikawa
  • Organizer: The Fourth A3 Roundtable Meeting on Chemical Probe Research Hub
  • Int'l Joint Research
• [Presentation] Synthesis and evaluation of a linear type of polyoxazole compounds for inducing anti-parallel topology aganst telomeric DNA (2019)
  • Author(s): Shogo Sasaki, Yue Ma, Hong-Liang Bao, Takumi Ishizuka, Yan Xu, Takatsugu Hirokawa, Kazuo Nagasawa
  • Organizer: The 46th International Symposium on Nucleic Acids Chemistry
  • Int'l Joint Research
• [Presentation] Synthesis of Aplysiatoxin/Oscillatoxin Family of Marine Natural Products. (2019)
  • Author(s): Toshio Nishikawa
  • Organizer: 27th International Society of Heterocyclic Chemistry (ISHC) Congress
  • Int'l Joint Research
• [Presentation] Synthesis of light-up type G4 ligands (2019)
  • Author(s): Yue Ma, Yuki Wakabayashi, Iida Keisuke, Ryota Saito, Kazuo Nagasawa
  • Organizer: The 7th International Meeting on Quadruplex Nucleic Acids
  • Int'l Joint Research
• [Presentation] Tankyrase and G-quadruplex as molecular targets for cancer therapy (2019)
  • Author(s): Seimiya H
  • Organizer: 第25回日本遺伝子細胞治療学会
  • Invited
• [Presentation] Target identification of bioactive small molecules based on proteomic analyses using 2-D DIGE (2019)
  • Author(s): Makoto Muroi, Ikuko Nagasawa, Naoko Ogawa, Harumi Aono, Yushi Futamura, Makoto Kawatani, Hiroyuki Osada
  • Organizer: RIKEN ? Max Planck Joint Research Center for System Chemical Biology 7th Symposium
  • Int'l Joint Research
• [Presentation] Telomere as the starting point of anticancer drug discovery (2019)
  • Author(s): Seimiya H
  • Organizer: The 7th Symposium, RIKEN-Max Planck Joint Research Center
  • Int'l Joint Research / Invited
• [Presentation] Temporal information representation of different modes of sensory stimuli for duration discrimination in monkey medial premotor areas. (2019)
  • Author(s): 千葉惇、守田和紀、生塩研一、稲瀬正彦
  • Organizer: Neuro2019
  • Int'l Joint Research
• [Presentation] The age-specific induction of MLL-AF9 regulates the leukemic transformation (2019)
  • Author(s): Ayaka Maeda, Sho Kubota, Yuqi Sun, Kimi Araki, Motomi Osato, Goro Sashida
  • Organizer: 第81回日本血液学会学術集会
• [Presentation] The development defect of serotonergic neuron induced by maternal immune activation. (2019)
  • Author(s): Jinmin Li, Fumihiro Shutoh, Tetsuya Sasaki, Yosuke Takei.
  • Organizer: Inauguration Symposium for the Neuroscience Program
  • Int'l Joint Research
• [Presentation] The developmental defect of Serotonergic neuron induced by maternal immune activation. (2019)
  • Author(s): Li jinmin, Tetsuya Sasaki, Fumihiro Shutoh, Yosuke Takei.
  • Organizer: 第42回日本神経科学大会・第62回日本神経化学会大会 合同大会
• [Presentation] The first report on newborn screening for MPS Ⅰ and Ⅱ in Fukuoka, Japan. (2019)
  • Author(s): Inoue T, Okuyama T, Endo F, Nakamura K, Hirose S.
  • Organizer: The 7th Asian Congress for Lysosomal Storage Disease Screening.
  • Int'l Joint Research
• [Presentation] The mechanism for generating low contrast-preferring neurons during orientation discrimination in rat primary visual cortex. (2019)
  • Author(s): Kimura R, Yoshimura Y
  • Organizer: NEURO2019 (The 42nd Annual Meeting of the Japan Neuroscience Society)
• [Presentation] The MEIOSIN-STRA8 complex directs cell cycle switching from mitosis to meiosis (2019)
  • Author(s): 石黒 啓一郎
  • Organizer: Gordon Research Conferences Germinal Stem Cell Biology
  • Int'l Joint Research
• [Presentation] The MEIOSIN-STRA8 complex directs cell cycle switching from mitosis to meiosis to establish the meiotic chromatin (2019)
  • Author(s): 石黒 啓一郎
  • Organizer: エピジェネティクス研究会
  • Invited
• [Presentation] The novel factor that process meiotic recombination intermediates (2019)
  • Author(s): 竹本 一政、高田 幸、杉本 道彦、荒木 喜美、石黒 啓一郎
  • Organizer: 第42回日本分子生物学会
• [Presentation] The role of primate striatum for decision making under different emotional context (2019)
  • Author(s): Kae Nakamura, Yasumasa Ueda, Masaharu Yasuda
  • Organizer: The 42nd Annual Meeting of the Japan Neuroscience Society
• [Presentation] The role of tryptophan metabolism in major depressive disorder (2019)
  • Author(s): Akihiro Mouri, Yuko Mori, Kazuo Kunisawa, Mami Hirakawa, Hisayoshi Kubota, Moe Niijima, Yasuko Yamamoto, Toshitaka Nabeshima, Kuniaki Saito
  • Organizer: AsCNP
  • Int'l Joint Research / Invited
• [Presentation] Time-restricted G-protein signaling through Gpr176/Gz/Rgs16 sets the pace of the central clock (2019)
  • Author(s): Masao Doi
  • Organizer: V World Congress for Chronobiology
  • Int'l Joint Research / Invited
• [Presentation] Txnl遺伝子ミスセンス変異ラットにおける脳-腎-心連関解析 (2019)
  • Author(s): 大守伊織
  • Organizer: 第12回ラットリソースリサーチ研究会
  • Invited
• [Presentation] Txnl遺伝子ミスセンス変異をもつ新規CKDモデルラット (2019)
  • Author(s): 大守伊織, 真下知士, 大内田守, 豊國伸哉
  • Organizer: 第62回日本腎臓病学会学術総会
• [Presentation] Txn1遺伝子変異ラットのてんかんの表現型 (2019)
  • Author(s): 大守伊織, 真下知土, 大内田守, 内藤有香, 今井宏彦, 豊國伸哉
  • Organizer: 第53回 日本てんかん学会
• [Presentation] T細胞におけるLUBACを介したNF-кB活性化機構の数理的解析 (2019)
  • Author(s): 畑中尚也、及川大輔、徳永文稔、鈴木貴
  • Organizer: 新学術領域研究「数理シク? ナル」第3回若手ワークショッフ?
• [Presentation] Understanding Postnatal Neurodevelopmental Disorders from Multiple Perspectives (2019)
  • Author(s): Aya Ito-Ishida
  • Organizer: RIKEN CBS Summer Program 2019
  • Int'l Joint Research / Invited
• [Presentation] Very long-chain lipids produced by the fatty acid clongase ELOVL1 are important for myelin formation and motor coordination. (2019)
  • Author(s): Sassa T, Isokawa M, Kihara A
  • Organizer: 60th International Conference on the Bioscience of Lipids
  • Int'l Joint Research
• [Presentation] Visualization of G-quadruplex in Living based on in situ Click reaction (2019)
  • Author(s): Mizuho Yasuda, Yue Ma, Sachiko Okabe, Young-Tae Chang, Hiroyuki Seimiya, Kazuo Nagasawa
  • Organizer: The 46th International Symposium on Nucleic Acids Chemistry
  • Int'l Joint Research
• [Presentation] Widefield sensory-evoked calcium imaging in excitatory and inhibitory neurons using a G-CaMP9a transgenic mouse. (2019)
  • Author(s): Masayuki Saskamoto, Masatoshi Inoue, Kazuki Sakai, Shigetaka Kobari, SayakaTakemoto-Kimura, Manabu Abe, Kenji Sakimura, Haruhiko Bito.
  • Organizer: Sculpted Light in the Brain
  • Int'l Joint Research
• [Presentation] X線マイクロイメージングから切り拓く昆虫の運動制御メカニズム (2019)
  • Author(s): 青沼 仁志
  • Organizer: 第89回日本動物学会シンポジウム「シンクロトロン放射光X線は動物学どう役立つか?-SPring-8 先端利用技術ワークショップ-」
  • Invited
• [Presentation] イオン恒常性の破綻による精神疾患発症機構の解明 (2019)
  • Author(s): 若月修二、荒木敏之
  • Organizer: 第42回日本分子生物学会年会ワークショップ「精神疾患の神経生物学」
• [Presentation] インターロイキン 17A による大脳皮質異常形成メカニズムの解明 (2019)
  • Author(s): 當銘幸貴、佐々木哲也、武井陽介
  • Organizer: 第107回日本解剖学会関東支部学術集会
• [Presentation] キネシン-1によるFrizzledの軸索輸送が神経終末のWntシグナルを制御する (2019)
  • Author(s): 満間百音、白木柚葉、齊藤遥、高田律子、山本融、高田慎治、羽田沙緒里、鈴木利治
  • Organizer: 第92回日本生化学会大会
• [Presentation] グアニン四重鎖を選択的に認識する大環状ヘキサオキサゾール化合物の創製 (2019)
  • Author(s): 馬悦
  • Organizer: 第13回バイオ関連化学シンポジウム2019
  • Invited
• [Presentation] グルタミン代謝の破綻による糖尿病発症とその分子メカニズム解明 (2019)
  • Author(s): 出口ハンナ、鈴木佐和子、石渡一樹、内藤久美子、山中典子、真鍋一郎、李恩瑛、三木隆司、龍野一郎、田中知明、小出尚史、横手幸太郎
  • Organizer: 第40回日本肥満学会総会
• [Presentation] グルタミン代謝遺伝子Glutaminase2が癌と生活習慣病に及ぼす影響 (2019)
  • Author(s): 鈴木佐和子、出口ハンナ、石渡一樹、内藤久美子、藤本真徳、李恩瑛、三木隆司、神田浩明、龍野一郎、小出尚史、田中知明、横手幸太郎
  • Organizer: 第40回日本肥満学会総会
• [Presentation] クロモドメインタンパクCdy12は幹細胞の多能性維持に重要である (2019)
  • Author(s): 服部奈緒子、木村佳那、飯田直子、今井俊夫、小泉美帆、本田浩章、牛島俊和
  • Organizer: 第13回日本エビジェネティクス研究会年会
• [Presentation] ケミカルツールを利用した四重鎖核酸の統合機能解析とその応用 (2019)
  • Author(s): 清宮啓之
  • Organizer: 化学コミュニケーションのフロンティア第6回公開シンポジウム
  • Invited
• [Presentation] シナプス形成抑制因子MDGA1の欠失による精神神経疾患様行動異常と、これを抑止する薬剤の探索 (2019)
  • Author(s): 多田 篤史, 田之上 優, 黒川 直弘, 窪田 剛志, 津島 希海, 尾嶋 大喜, Razib Hossain, 高橋 弘雄, 岸本泰司, 山本 融
  • Organizer: 日本薬学会第140年会
• [Presentation] シナプス形成抑制因子MDGAファミリー分子群の欠失が引き起こすE/Iバランス偏移がもたらす認知・行動異常 (2019)
  • Author(s): 山本 融, 尾嶋 大喜, Razib Hossain, 多田 篤史, 黒川 直弘, 長澤 研, 琢磨 和晃, 中井 雄規, 高橋 弘雄, 冨永 貴志, 岸本 泰司
  • Organizer: 第42回日本神経科学大会
• [Presentation] ジペプチジルペプチダーゼ-3が糖尿病での心腎機能悪化を抑制 (2019)
  • Author(s): 清水昭男、Xiaoling Pang、扇田久和
  • Organizer: 日本血管生物医学会学術集会(CVMW2019)
• [Presentation] ジペプチジルペプチダーゼ-3が糖尿病での腎機能悪化を抑制 (2019)
  • Author(s): 大東親生、清水昭男、Xiaoling Pang、扇田久和
  • Organizer: 日本生化学会近畿支部例会
• [Presentation] ショウジョウバエ生殖質形成を促進する新規小タンパク質 (2019)
  • Author(s): 中村輝
  • Organizer: 2019遺伝研研究会 有性生殖における染色体・クロマチン・核動態に関する研究会
  • Invited
• [Presentation] シングルセルRNAseqを基点とした傍口腔上皮幹細胞の同定 (2019)
  • Author(s): 上野博夫
  • Organizer: 第71回日本細胞生物学会大会(第19回日本蛋白質科学会年会合同年次大会)
  • Invited
• [Presentation] シングルセルRNAシークエンス解析によるメラノーマ患者におけるPD-1抗体治療反応性と相関する末梢血CD8+T細胞サブセット (2019)
  • Author(s): 松本 大地, 大多 茂樹, 南雲 春菜, 藤田 知信, 高橋 聡, 並川 健二郎, 北野 滋久, 山崎 直也, 河上 裕
  • Organizer: 第78回日本癌学会学術総会
• [Presentation] シンポジウム7 : マウスモデルを用いた発がん研究を再考する 発がん実験から確立されたフェロトーシスのコンセプト (2019)
  • Author(s): 豊國伸哉
  • Organizer: 第78回日本癌学会学術総会
• [Presentation] ストレス応答 MAP キナーゼによるmiRNAの発現調節とアポトーシス誘導機構の解明 (2019)
  • Author(s): 渡海 紀子, 中村 貴紀, 武川 睦寛
  • Organizer: 第78回 日本癌学会学術総会
• [Presentation] ストレス顆粒形成を制御する分子機構の解析 (2019)
  • Author(s): 橋本 夏葉, 中村 貴紀, 武川 睦寛
  • Organizer: 第42回日本分子生物学会
• [Presentation] ストレス顆粒形成促進因子NFAR2の天然変性領域が担う液-液相分離の生理的意義の解析 (2019)
  • Author(s): 山下映, 藤井一希, 腰高由美恵, 安達真由美, 笹川恵理, 中川真一, 高雄啓三, 椎名伸之
  • Organizer: 第42回日本分子生物学会年会
• [Presentation] ダウン症モデルマウスからがんや血管病の治療・予防法を探る (2019)
  • Author(s): 南 敬
  • Organizer: 第2回日本ダウン症会議
• [Presentation] テトラヒドロイソキノリンアルカロイド群の化学-酵素ハイブリッド全合成 (2019)
  • Author(s): 谷藤 涼
  • Organizer: 若手研究者のための有機化学札幌セミナー
  • Invited
• [Presentation] てんかんと遺伝子 (2019)
  • Author(s): 廣瀬伸一
  • Organizer: 第14回日本てんかん学会九州地方会 in OKINAWA
  • Invited
• [Presentation] トポイソメラーゼ阻害薬ラメラリンの標的指向性変換による薬剤耐性EGFR阻害剤の創出 (2019)
  • Author(s): 西谷直之, 福田勉
  • Organizer: 第14回日本がん分子標的治療学会TRワークショップ
  • Invited
• [Presentation] トリプトファン代謝経路が抑うつに与える影響-基礎研究と臨床研究のクロストークー (2019)
  • Author(s): 毛利彰宏、國澤和生、窪田悠力、新島萌、森優子、勅使河原知明、藤垣英嗣、山本康子、尾崎紀夫、齋藤邦明、鍋島俊隆
  • Organizer: 次世代を担う創薬・医療薬理シンポジウム2019
• [Presentation] ノビレチン類似体の簡便な合成と腫瘍細胞増殖阻害活性 (2019)
  • Author(s): 速水 勇貴、橋本 博、石川 吉伸
  • Organizer: 第8回食品薬学シンホ?シ?ウム
• [Presentation] パラジウム触媒とトリエチルホウ素を用いた3-ヒドロキシー4-ペンテン酸とアルデヒドとのカップリング反応 (2019)
  • Author(s): 仲尾純弥, 神路祗里歩, 福田勉, 小野寺玄, 木村正成
  • Organizer: 第66回有機金属化学討論会
• [Presentation] パラジウム触媒とホスフィンーポラン配位子を用いたアルデヒドのα位アリル化反応 (2019)
  • Author(s): 早崎匠杜, 小野寺玄, 福田勉, 木村正成
  • Organizer: 第56回化学関連支部合同九州大会
• [Presentation] ファイバーレス光遺伝学の開発とその応用による神経回路機能の同定 (2019)
  • Author(s): 山中章弘
  • Organizer: 異分野融合による次世代光生物学? 研究会
  • Invited
• [Presentation] フェルスター共鳴エネルギー移動の原理に基づく二光子励起用光遺伝学ツールの開発 (2019)
  • Author(s): 金城 智章、寺井 健太、堀田 彰一朗、野村 紀通、隅山 健太、岩田 想、富樫かおり、松田 道行
  • Organizer: 第19回日本蛋白質科学会年会/第71回日本細胞生物学会大会 合同年次大会
• [Presentation] フェロトーシスの視点からみる低温プラズマの医療応用 ワークショップ1 大気圧プラズマによる活性酸素種の生成と生物応答 (2019)
  • Author(s): 豊國伸哉、蒋 麗、岡崎泰昌
  • Organizer: 第72回日本酸化ストレス学会学術集会
• [Presentation] ホスフィンーボラン配位子と金触媒を用いたアルキン部位を有するマロン酸エステル誘導体のConia-Ene反応 (2019)
  • Author(s): 桑原麟太郎, 小野寺玄, 福田勉, Krause Norbert, 木村正成
  • Organizer: 第56回化学関連支部合同九州大会
• [Presentation] ホスフィンーボラン配位子を用いたアリルアルコールによるカルボニル化合物のα位アリル化反応 (2019)
  • Author(s): 戸上翔太郎, 早崎匠杜, 清水愛香, 福田勉, 小野寺玄, 木村正成
  • Organizer: 第66回有機金属化学討論会
• [Presentation] マウスにおける神経幹細胞特異的ITPA欠損は神経細胞の脱分極を引き起こし、てんかん性発作と早期死亡の原因となる (2019)
  • Author(s): 土本 大介、古賀 祐一郎、林 良憲、アボルハッサニ ノナ、米嶋 康臣、作見邦彦、中西 博、豊國 伸哉、中別府 雄作
  • Organizer: 第42回日本分子生物学会年会
• [Presentation] マウス系統間のPak1-3' UTRのSNPsはPAK1発現減少と腫瘍抑制に関連する (2019)
  • Author(s): 奥村和弘, 齋藤 慈, 磯貝恵理子, 荒木喜美, 若林雄一
  • Organizer: 第66回実験動物学会総会
• [Presentation] マウス順遺伝学、ゲノム編集、疾患ゲノム解析による慢性再発性多発性骨髄炎の分子機構解明 (2019)
  • Author(s): 阿部幸一郎
  • Organizer: 第91回日本遺伝学会大会
  • Invited
• [Presentation] ミトコンドリア内葉酸代謝経路酵素阻害による抗腫瘍効果の評価ならびにその機序の解明 (2019)
  • Author(s): 西村建徳、中田飛鳥、Chen Xiaoxi、西くるみ、堀家-目黒牧子、佐々木宗一郎、北賢二、堀家慎一、齋藤香織、加藤啓子、五十嵐香織、村山貴彦、河野響、高橋智聡、向田直史、矢野聖二、曽我朋義、東條有伸、後藤典子
  • Organizer: 第29回日本サイトメトリー学会学術集会
• [Presentation] ミトコンドリア内葉酸代謝酵素MTHFD2を分子標的とした際の抗腫瘍効果の評価 (2019)
  • Author(s): 西村建徳、佐々木宗一郎、村山貴彦、向田直史、矢野聖二、曽我朋義、後藤典子
  • Organizer: 第23回日本がん分子標的治療学会学術集会
• [Presentation] メトトレキサート誘発性上皮間葉転換に及ぼすPAI-1の影響解析 (2019)
  • Author(s): 川見昌史、山上洋平、湯元良子、高野幹久
  • Organizer: 第11回日本RNAi研究会
• [Presentation] ランダムインテグレーション評価法(RAIS2)の開発と検査・解析サービスの展開 (2019)
  • Author(s): 斎藤益満(発表代表者・責任発表者)、長谷川寛雄、佐々木大介、山内俊輔、和田 悠作、松平 崇弘
  • Organizer: 第6回日本HTLV-1学会学術集会
• [Presentation] レム睡眠を調節する神経回路の機能と操作 (2019)
  • Author(s): 山中章弘
  • Organizer: 日本睡眠学会第44回定期学術集会 睡眠科学研究講座
  • Invited
• [Presentation] 移植部位が清掃移植の成否に及ぼす影響 (2019)
  • Author(s): 花岡賢人、土本彬広、高島誠司
  • Organizer: 第112回日本繁殖生物学会
• [Presentation] 遺伝子にコードされた膜電位センサーとその応用 (2019)
  • Author(s): 坂本 雅行
  • Organizer: Neuro2019
  • Int'l Joint Research / Invited
• [Presentation] 炎症性サイトカインインターロイキン1の活性異常が引き起こす雌性不妊不妊の病態解明 (2019)
  • Author(s): 武政大地、正木魁人、中野愛里、角田茂、久和茂、高島誠司
  • Organizer: 第112回日本繁殖生物学会
• [Presentation] 化学合成とin vitro酵素変換の融合による多環性アルカロイドの迅速合成 (2019)
  • Author(s): 谷藤 涼
  • Organizer: 酵素研究助成 第45回研究発表会
• [Presentation] 加齢マウスへの亜鉛の長期間過剩投与による学習・記憶障害について (2019)
  • Author(s): 吉田 香, 魏 民, 藤岡 正喜, 寺本 勲
  • Organizer: 第30回 日本微量元素学会
• [Presentation] 褐色脂肪研究を通した肥満関連疾患の新規治療標的分子の探索 (2019)
  • Author(s): 清水逸平
  • Organizer: 心血管内分泌代謝学会2019
  • Invited
• [Presentation] 冠動脈周囲脂肪組織が動脈硬化に及ぼす影響 (2019)
  • Author(s): 鈴木友彰、扇田久和、佐藤朗、木下武、高島範之、近藤康生、宮下史寛、鉢呂康平、脇坂穂高
  • Organizer: 日本冠疾患学会学術集会
• [Presentation] 幹細胞の多能性維持に関与するヒストンリーダーCdy12の同定 (2019)
  • Author(s): 服部奈緒子、木村佳那、飯田直子、今井俊夫、小泉美帆、本田浩章、牛島俊和
  • Organizer: 第42回日本分子生物学会年会
• [Presentation] 環境要因により影響を受ける認知機能に対するアプローチ (2019)
  • Author(s): 上田(石原)奈津実、木下専
  • Organizer: 資生堂女性研究者サイエンスグラント受賞者 特別講演会
  • Invited
• [Presentation] 癌内線維芽細胞による癌細胞の浸潤・転移促進機構 (2019)
  • Author(s): 折茂彰
  • Organizer: 東京歯科大学大学院セミナー
  • Invited
• [Presentation] 癌抑制遺伝子p53を活性化する新たながん分子標的治療薬の創生 (2019)
  • Author(s): 河原康一, 下川倫子, 川畑拓斗, 古川龍彦
  • Organizer: 第92回日本生化学会大会
• [Presentation] 急性ストレス負荷によるコカイン欲求行動増強における内側前頭前野ノルアドレナリン神経伝達の役割 (2019)
  • Author(s): ZhangTong, 和田進太郎, 柳田淳子, 笹瀬人暉, LiXueting, 上居寛典, 堂本将輝, 出山諭司, 檜井栄一, 山中章弘, 西谷直也, 永安一樹, 金子周司, 南雅文, 金田勝幸
  • Organizer: 生体機能と創薬シンポジウム2019
• [Presentation] 強い抗がん選択性を持つCDK4/6を標的とした新規ラメラリン類縁体の同定 (2019)
  • Author(s): 大橋愛美, 福田勉, 岡村睦美, 西谷直之, 宇野佑子, 澤匡明, 岩尾正倫, 旦慎吾
  • Organizer: 第78回日本癌学会学術総会
• [Presentation] 教育講演 : アスベスト曝露による中皮腫発症機構の解明とその予防 (2019)
  • Author(s): 豊國伸哉
  • Organizer: 第1回日本石綿・中皮腫学会学術集会
  • Invited
• [Presentation] 血小板による骨肉腫の転移誘導 (2019)
  • Author(s): 市川 二郎, 安藤 隆, 川崎 朋範, 斎藤 正夫, 井上 克枝, 波呂 浩孝
  • Organizer: 第34回日本整形外科学会基礎学術集会
• [Presentation] 血小板による骨肉腫の転移誘導 (2019)
  • Author(s): 市川 二郎, 安藤 隆, 波呂 浩孝
  • Organizer: 第92回日本整形外科学会学術総会
• [Presentation] 減数分裂型の細胞周期プログラムへの切替え (2019)
  • Author(s): 石黒 啓一郎
  • Organizer: 第37回染色体ワークショップ・第18回核ダイナミクス研究会
• [Presentation] 甲状腺未分化癌における多能性関連遺伝子群の発現 (2019)
  • Author(s): 柴田 博史, 大橋 敏充, 西堀 丈純, 久世 文也, 宮崎 龍彦, 青木 光広
  • Organizer: 第43回 日本頭頸部癌学会
• [Presentation] 骨肉腫のインスリンシグナルによる形態変化と治療低抗性獲得 (2019)
  • Author(s): 清水孝恒、武藤章弘、佐谷秀行
  • Organizer: 第50回日本臨床分子形態学会総会・学術集会
• [Presentation] 骨肉腫難治例の治療低抗性分子機構の解明と新規治療法開発にむけた基礎的検討 (2019)
  • Author(s): 清水孝恒、武藤章弘、佐谷秀行
  • Organizer: 第13回日本緩和医療薬学会年会
  • Invited
• [Presentation] 四重鎖核酸ケモプローブに対する細胞応答の解明とがん創薬への応用 (2019)
  • Author(s): 清宮啓之
  • Organizer: 第92回日本生化学会大会
  • Invited
• [Presentation] 脂肪組織におけるミトコンドリアオートファジーの生理的意義 (2019)
  • Author(s): 神吉智丈
  • Organizer: 第66回日本実験動物学会総会
  • Invited
• [Presentation] 視覚異常マウスにおける精神疾患様行動の発現機構解析 (2019)
  • Author(s): Tesshu Hori, Shohei Ikuta, Tomokazu Yoshida, Kenji Sakimura, Keizo Takao, Satoko Hattori, Tsutomu Miyakawa, Reiko Kobayakawa, Chieko Koike
  • Organizer: 次世代脳プロジェクト2019年度冬のシンポジウム
• [Presentation] 次世代HTLV-1クロナリティ解析法(RAIS1)の開発とその進捗 (2019)
  • Author(s): 山内 俊輔(発表代表者)、長谷川 寛雄(責任発表者)、斎藤 益満(研究分担者)、佐々木 大介、今泉 芳孝、柳原 克紀
  • Organizer: 第6回日本HTLV-1学会学術集会
• [Presentation] 自然免疫制御に関わる新規脱ユビキチン化酵素OTUD1の同定と生理機能解析 (2019)
  • Author(s): 駒倉啓大、及川大輔、徳永文稔
  • Organizer: 第24回日本病態プロテアーゼ学会
• [Presentation] 種々の生体ストレス反応における、Claspinのストレス応答メディエーターとしての役割 (2019)
  • Author(s): Yang, C. -C, Mayumi, Shindo, Hisao Masai
  • Organizer: 第42回 日本分子生物学会年会
• [Presentation] 腫瘍細胞に優先的にp53応答を引き出す新たながん分子標的治療薬の創生 (2019)
  • Author(s): 河原康一、川畑拓斗、山本雅達、新里能成、古川龍彦
  • Organizer: 第78回日本癌学会学術総会
• [Presentation] 腫瘍細胞へ優先的にp53応答を引き出す新たながん分子標的治療薬の創生 (2019)
  • Author(s): 河原 康一, 下川 倫子, 古川 龍彦
  • Organizer: 第57回日本癌治療学会学術集会
• [Presentation] 腫瘍細胞へ優先的にp53応答を来す新たながん分子標的治療薬 (2019)
  • Author(s): 河原 康一、下川 倫子、古川 龍彦
  • Organizer: 第23回日本がん分子標的治療学会学術集会
• [Presentation] 腫瘍優先的にp53経路の活性化を起こす新たな分子標的治療薬の開発 (2019)
  • Author(s): 河原 康一、古川 龍彦
  • Organizer: 第42回日本分子生物学会年会
• [Presentation] 順遺伝学に基づくMSMマウスの発がん低抗性の解明 (2019)
  • Author(s): 奥村和弘, 齋藤 慈, 磯貝恵理子, 荒木喜美, 若林雄一
  • Organizer: 第34回発癌病理研究会
• [Presentation] 小児てんかん性脳症の革新的創薬を見据えた病態解析 (2019)
  • Author(s): 廣瀬伸一
  • Organizer: 令和元年度AMED再生医療研究交流会
  • Invited
• [Presentation] 小胞体膜分子Derlin-1の成体海馬ニューロン新生における役割 (2019)
  • Author(s): 村尾直哉、西頭英起
  • Organizer: 第42回日本分子生物学会年会
• [Presentation] 食物アレルギー及び自己免疫疾患におけるIgAの影響 (2019)
  • Author(s): 小竹久仁彦、安達貴弘
  • Organizer: 日本食品免疫学会設立15周年記念学術大会
• [Presentation] 新しいゲノムシグナチャーとしてのRNA-DNAハイブリッドとグアニン4重鎖 (2019)
  • Author(s): 正井久雄、加納豊、田中卓、伊藤さゆり、深津理乃、森山賢治、鷺朋子、覺正直子、吉沢直子、井口智成、加藤宏幸
  • Organizer: 第92回日本生化学会大会 シンポジウム『新しいゲノムの姿とその維持機構のフレキシビリティ』
  • Invited
• [Presentation] 新規PKCリガンドの開発とHIVのShock&Kill療法への応用 (2019)
  • Author(s): 入江一浩
  • Organizer: 新学術領域研究(化学コミュニ)第6回公開シンポジウム
  • Invited
• [Presentation] 新規ポリペプチドによる恒常性維持機構 (2019)
  • Author(s): 松本 有樹修
  • Organizer: 第71回日本細胞生物学会大会
• [Presentation] 神経活動操作による睡眠覚醒調節神経の機能的同定 (2019)
  • Author(s): 山中章弘
  • Organizer: 日本睡眠学会第44回定期学術集会 シンポジウム33
  • Invited
• [Presentation] 神経細胞resonance特性におけるKvllチャネルの関与 (2019)
  • Author(s): 松岡利典、山崎美和子、阿部学、松田由喜子, 森野豊之, 川上秀史, 崎村建司、渡辺雅彦、橋本浩一
  • Organizer: 広島神経医科学研究会
• [Presentation] 睡眠覚醒状態変化に関わる神経回路の機能的同定 (2019)
  • Author(s): 山中章弘
  • Organizer: 第42回日本神経科学大会
  • Invited
• [Presentation] 睡眠覚醒調節神経と痛みの制御 (2019)
  • Author(s): 山中章弘
  • Organizer: 第13回日本緩和医療薬学会年会
  • Invited
• [Presentation] 数理解析を活用した中心体複製開始を制御する分子機構の解明 (2019)
  • Author(s): 中村 貴紀, 西住(渡海) 紀子, 中澤 嵩, 森 竜樹, 鈴木 貴, 武川 睦寛
  • Organizer: 第78回 日本癌学会学術総会
  • Invited
• [Presentation] 正常-がん細胞間作用によるフォーカス形成制御機構の化学生物学的解析 (2019)
  • Author(s): 青山 愛, 藤元 次郎, 仙波 憲太郎
  • Organizer: In vivo イメージングフォーラム2019
• [Presentation] 正常-がん細胞間作用によるフォーカス形成制御機構の化学生物学的解析 (2019)
  • Author(s): 青山 愛, 藤元 次郎, 平野 弘之, 渡辺 信元, 長田 裕之, 仙波 憲太郎
  • Organizer: 第42回日本分子生物学会年会
• [Presentation] 生合成拡張型合成の新展開と機能創発への挑戦 (2019)
  • Author(s): 大栗博毅
  • Organizer: 理研シンポジウム : 第14回有機合成化学フロンティア
  • Invited
• [Presentation] 生合成拡張型合成プロセスの開発と機能性中分子群創製 (2019)
  • Author(s): 大栗博毅
  • Organizer: 微生物ウィーク2019コラポシンポジウム : 放線菌が生産する構造多様性に富んだ化合物とその応用への展開
  • Invited
• [Presentation] 生殖細胞における体細胞分裂から減数分裂への切替え機構 (2019)
  • Author(s): 石黒 啓一郎
  • Organizer: 第125回日本解剖学会総会
  • Invited
• [Presentation] 生殖細胞特異的ジンクフィンガータンパク質は減数分裂前期パキテン脱出の転写制御に働く (2019)
  • Author(s): 高田 幸, 小寺 千聡, 竹本 一政, 前田 亮, 坂下 陽彦, 松浦 公美, 丹羽 仁史, 立花 誠, 行川 賢, 荒木 喜美, 石黒 啓一郎
  • Organizer: 第42回日本分子生物学会
• [Presentation] 精上皮周期に伴う精子幹細胞自己複製因子の発言変化と未分化型精原細胞の動態 (2019)
  • Author(s): 中野愛里、高島誠司
  • Organizer: 第112回日本繁殖生物学会
• [Presentation] 染色体整列因子CAMP(CHAMP1)欠損による知的障害発症メカニズムの解明 (2019)
  • Author(s): 永井正義、家村顕自、服部聡子、吉川貴子、萩原英雄、安澤隼人、木下賢吾、大隅典子、宮川剛、田中耕三
  • Organizer: 第42回日本分子生物学会年会
• [Presentation] 線条体直接路ニューロンと間接路ニューロンの周波数応答特性は異なる (2019)
  • Author(s): 稲垣 良, 笹川 正人, 小山内 実
  • Organizer: 第34回日本大脳基底核研究会
• [Presentation] 線条体投射ニューロンの周波数応答特性は直接路と間接路で異なる (2019)
  • Author(s): 稲垣 良, 笹川 正人, 小山内 実
  • Organizer: 2019年電気学会 電子・情報・システム部門大会
• [Presentation] 選択的オートファジーによる転写制御 (2019)
  • Author(s): 小松雅明
  • Organizer: 第66回日本実験動物学会
  • Invited
• [Presentation] 選択的マクロオートファジー、分子から生理機能まで (2019)
  • Author(s): 小松雅明
  • Organizer: 第92回日本生化学会
  • Invited
• [Presentation] 早期ライフステージにおける神経回路成熟機構の解明 (2019)
  • Author(s): 石田綾
  • Organizer: AMED-Prime「早期ライフ」研究開発領域キックオフ会議
• [Presentation] 多色細胞系譜追跡法とsingle cell RNAseq を基点とした成体幹細胞の同定 (2019)
  • Author(s): 上野博夫
  • Organizer: 愛媛大学TRCセミナー
  • Invited
• [Presentation] 多色細胞系譜追跡法とsingle cell RNAseq を基点とした成体幹細胞の同定 (2019)
  • Author(s): 上野博夫
  • Organizer: 慶應義塾大学JKiCセミナー
  • Invited
• [Presentation] 多色細胞系譜追跡法とsingle cell RNAseq を基点とした成体幹細胞の同定 (2019)
  • Author(s): 上野博夫
  • Organizer: 昭和大学学士会後援セミナー
  • Invited
• [Presentation] 多色細胞系譜追跡法とsingle cell RNAseqを基点とした成体幹細胞の同定 (2019)
  • Author(s): 上野博夫
  • Organizer: 鳥取大学染色体工学研究センターセミナー
  • Invited
• [Presentation] 多臓器転移誘導遺伝子HNF1Bの同定と機能解析 (2019)
  • Author(s): 中山淳、二口充、仙波憲太郎
  • Organizer: 第42回日本分子生物学会年会
• [Presentation] 体細胞分裂から減数分裂への細胞周期の切替え機構 (2019)
  • Author(s): 石黒 啓一郎
  • Organizer: 日本遺伝学会 第91回大会
• [Presentation] 体細胞分裂から減数分裂への切替え機構 (2019)
  • Author(s): 石黒 啓一郎
  • Organizer: 第42回日本分子生物学会
• [Presentation] 胎児期に母体のメチル基供与体の減少に暴露されたマウスの神経行動学的表現型解析 (2019)
  • Author(s): 古瀬民生、山田郁子、串田知子、尾崎藍、三浦郁生、上野正樹、田村勝
  • Organizer: 第42回分子生物学会
• [Presentation] 大環状へキサオキサゾール誘導体を用いたグアニン四重鎖を標的とするLight-up型蛍光リガンドの創製 (2019)
  • Author(s): 若林勇樹, 馬悦, 飯田圭介, 齋藤良太, 長澤和夫
  • Organizer: 日本ケミカルバイオロジー学会 第14回年会
• [Presentation] 第3世代EGFRチロシンキナーゼ阻害薬耐性非小細胞肺癌に対するLamellarin14とCetuximab併用効果の検討 (2019)
  • Author(s): 阿部壮矩, 渡辺菜美, 佐京智子, 奥裕介, 福田勉, 旦慎吾, 矢守隆夫, 石橋郁人, 上原至雅, 岩尾正倫, 西谷直之
  • Organizer: 第58回日本薬学会東北支部大会
• [Presentation] 脱アセチル化酵素SIRT7によるNF-kB p65の核外輸送制御メカニズムの解明 (2019)
  • Author(s): 藤叔史、Sobuz Shihab U., 吉澤達也、Fazlul Karim、小野勝彦、澤智裕、宮本洋一、岡正啓、山縣和也
  • Organizer: 第42回日本分子生物学会
• [Presentation] 脱ユビキチン化酵素OTUD1によるNF-кB経路とインターフェロン産生経路の相反的制御 (2019)
  • Author(s): 駒倉啓大、及川大輔、徳永文稔
  • Organizer: 第42回日本分子生物学会
• [Presentation] 中心体複製初期に起こるPLK4の中心体輸送機構 (2019)
  • Author(s): 中村 貴紀, 西住(渡海) 紀子, 中澤 嵩, 森 竜樹, 鈴木 貴, 武川 睦寛
  • Organizer: 第19回日本蛋白質科学年会・第71回日本細胞生物学会 合同年次大会
  • Int'l Joint Research / Invited
• [Presentation] 長期記憶保持に必要な分子・細胞基盤の解明 (2019)
  • Author(s): 上田(石原)奈津実、木下専
  • Organizer: 2019 GTR Seeds Seminar
  • Invited
• [Presentation] 直鎖状ポリユビキチン鎖結合タンパク質ZnUBPファミリーのNF-кB抑制機構の解明 (2019)
  • Author(s): 高橋宏隆、及川大輔、長尾和哉、岩崎誠、今井祐記、徳永文稔、澤崎達也
  • Organizer: 第42回日本分子生物学会年会
• [Presentation] 直鎖状ユビキチン鎖を足場とした免疫シグナル制御に関する数理モデル解析 (2019)
  • Author(s): 及川大輔
  • Organizer: 日本応用数理学会
  • Invited
• [Presentation] 低酸素ストレスはBhlhe40-Mafa経路を介してインスリン分泌不全を誘導する (2019)
  • Author(s): 津山友徳、佐藤叔史、吉澤達也、松岡孝昭、山縣和也
  • Organizer: 第42回日本分子生物学会
• [Presentation] 低酸素応答によるミエリン形成制御 (2019)
  • Author(s): 若月修二、氏家悠佳、荒木敏之
  • Organizer: 第五回日本ミエリン研究会
• [Presentation] 低酸素誘導性BHLHE40によるβ細胞機能低下機序の解明 (2019)
  • Author(s): 佐藤叔史、津山友徳、吉澤達也、松岡孝昭、山縣和也
  • Organizer: 第62回日本糖尿病学会年次学術集会
• [Presentation] 鉄を介した酸化ストレスによる動物発がんモデルとゲノム変化 (2019)
  • Author(s): 赤塚慎也、蒋麗、伊藤文哉、豊國伸哉
  • Organizer: 第78回日本癌学会学術総会
• [Presentation] 銅触媒による末端アルキンと有機ホウ素及びアルデヒドを用いたオキサポロールの新規合成反応の開発 (2019)
  • Author(s): 布田旭, 阿嘉由樹, 福田勉, 小野寺玄, 木村正成
  • Organizer: 第66回有機金属化学討論会
• [Presentation] 軟骨細胞分化のエビジェネティクス機構 (2019)
  • Author(s): 波多賢二
  • Organizer: 第33回日本軟骨代謝学会
  • Invited
• [Presentation] 日本産野生由来近交系マウスMSMを用いた皮膚がん修飾因子の同定 (2019)
  • Author(s): 奥村和弘、斎藤慈、磯貝恵理子、若林雄一
  • Organizer: 第78回日本癌学会学術総会
  • Invited
• [Presentation] 乳がんの治療薬抵抗性獲得機構におけるNFYAの機能解明 (2019)
  • Author(s): 岡田宣宏、辻本剛己、村中勇人、高橋智聡
  • Organizer: 【先端モデル動物支援プラットフォーム】若手支援技術講習会
• [Presentation] 妊娠中の偏った必須脂肪酸摂取は子において快楽的摂食を促す (2019)
  • Author(s): 酒寄信幸、樋口央紀、深堀良二、井口善生、瀬戸川将、宮澤陽夫、小林和人
  • Organizer: 日本食品科学工学会東北支部(令和元年大会)および日本栄養・食糧学会東北支部(第53回大会)合同支部大会
• [Presentation] 妊娠中の偏った必須脂肪酸摂取は子において嗜好食品摂取を促す (2019)
  • Author(s): 酒寄信幸, 樋口央紀, 深堀良二, 井口善生, 瀬戸川将, 永塚貴弘, 宮澤陽夫, 小林和人
  • Organizer: 日本脂質栄養学会第28回大会
• [Presentation] 肺胞上皮細胞におけるメトトレキサート誘発性上皮間葉転換とPAI-1の関連解析 (2019)
  • Author(s): 山上洋平、二木空人、湯元良子、川見昌史、高野幹久
  • Organizer: 第13回次世代を担う若手医療薬科学シンポジウム
• [Presentation] 肺胞上皮細胞における薬物誘発性上皮間葉転換を抑制する化合物の探索とその特性解析 (2019)
  • Author(s): 川見昌史、妹尾俊祐、山上洋平、湯元良子、高野幹久
  • Organizer: 日本薬剤学会第34年会
• [Presentation] 発達期小脳のプルキンエ細胞における登上線維シナプス刈り込みのPcdh10依存的特異性 (2019)
  • Author(s): 渡邉貴樹
  • Organizer: 2019年度若手支援技術講習会
• [Presentation] 発達障害の病態理解に向けた小脳-前頭前野-領野連関の解明 (2019)
  • Author(s): 石田綾
  • Organizer: 新学術領域「脳情報動態」領域会議
• [Presentation] 部位特異的蛍光標識を用いたドーパミンに応答するチロシン水酸化酵素の構造変化の解析 (2019)
  • Author(s): 犬飼駿弥, 原怜, 一瀬宏
  • Organizer: Neuro2019(第42回日本神経科学大会・第62回日本神経化学大会)
• [Presentation] 複製タイミング制御因子Rif1の欠失が誘導する2細胞期胚様細胞のエンハンサー構造 (2019)
  • Author(s): 吉沢直子、正井久雄
  • Organizer: 第42回 日本分子生物学会年会
• [Presentation] 弁別行動の獲得過程における線条体局所領域間の機能シフト (2019)
  • Author(s): 瀬戸川将
  • Organizer: 生理研研究会2019「行動の多様性を支える神経基盤とその動作様式の解明」
  • Invited
• [Presentation] 母親の偏った必須脂肪酸摂取はドパミンニューロンの過剩産生を介して子の快楽的摂食を促す (2019)
  • Author(s): 酒寄信幸
  • Organizer: 第42回日本分子生物学会年会
  • Invited
• [Presentation] 母親の偏った必須脂肪酸摂取は子において嗜好食品の摂取を促す (2019)
  • Author(s): 酒寄信幸, 小林和人
  • Organizer: 第4回食欲・食嗜好の分子・神経基盤研究会
• [Presentation] 母体の遺伝子変異がマウス野生型産仔の表現型解析結果に与える影響 (2019)
  • Author(s): 古瀬民生、山田郁子、串田知子、三浦郁生、尾崎藍、永瀬茜、若菜茂晴、田村勝
  • Organizer: 第66回日本実験動物学会
• [Presentation] 味蕾幹細胞の同定と解析 (2019)
  • Author(s): 上野博夫
  • Organizer: 第53回日本味と匂学会
  • Invited
• [Presentation] 目標指向行動の動機づけにおける腹側被蓋野D2受容体陽性ドーパミンニューロンの役割 (2019)
  • Author(s): 井口善生・中山義貴・加藤成樹・小林和人
  • Organizer: 福島県立医科大学研究連携セミナー2019年度ポスター発表会-学内研究の連携と活性化に向けて-
• [Presentation] 薬剤耐性EGFR T790M/C797Sに対するlamellarinとcetuximabの併用効果 (2019)
  • Author(s): 西谷直之, 佐京智子, 奥裕介, 福田勉, 旦慎吾, 矢守隆夫, 石橋郁人, 上原至雅, 岩尾正倫
  • Organizer: 第23回日本がん分子標的治療学会学術集会
• [Presentation] 両側副腎皮膚大結節性過形成の新たな分子病態の解明 (2019)
  • Author(s): 鈴木佐和子
  • Organizer: 第20回日本内分泌関東甲信越地方会
  • Invited
• [Presentation] 霊長類の大脳皮質領野形成とその破綻による精神疾患発症メカニズム (2019)
  • Author(s): 佐々木哲也
  • Organizer: 第23回予防衛生協会セミナー
  • Invited
• [Presentation] 老化促進代謝物質による加齢同期メカニズムの解明 (2019)
  • Author(s): 清水逸平
  • Organizer: 日本抗加齢協会第四回学術フォーラム
  • Invited
• [Presentation] 老化促進代謝物質を介した加齢同期メカニズムの解明 (2019)
  • Author(s): 清水逸平
  • Organizer: 日本体力医学会大会
  • Invited
• [Presentation] Claspin as a general mediator molecule that responds to various cellular stress
• [Presentation] Role of Derlin-1 in the maintenance of stem cell populations in adult hippocampal neurogenesis
• [Presentation] Unique enhancers structures in 2-cell zygote-like mouse ES cells induced by loss of replication timing regulator Rif1.
• [Presentation] Role of D2 receptor-positive ventral tegmental area dopamine neurons in effort-related motivation for food-seeking
• [Book] 分子呼吸器病Vol.24 No.1、「SASPによる慢性炎症とその制御」 (2020)
  • Author(s): 大森徳貴、城村由和
  • Total Pages: 91
  • Publisher: 先端医学社
• [Book] 医薬品開発におけるオミクス解析技術-ゲノム・トランスクリプトーム・プロテオーム・メタポローム-「薬剤標的分子同定を目的としたプロテオーム解析の手法」 (2020)
  • Author(s): 室井誠、小川直子、長田裕之
  • Total Pages: 181
  • Publisher: 情報機構
• [Book] Ultra-thin fluorescence endoscope imaging system enables flexible functional brain imaging. (2020)
  • Author(s): Osanai M, Miwa H, Tamura A, Kikuta S, Iguchi Y, Yanagawa Y, Kobayashi K, Mushiake H.
  • Publisher: Springer.
• [Book] 生き物と音の事典 (2019)
  • Author(s): 高梨琢磨、松尾行雄、力丸裕、宋文杰, (他5名)編集
  • Total Pages: 464
  • Publisher: 朝倉書店
• [Book] 進化するがん創薬 (2019)
  • Author(s): 清宮啓之(編)
  • Total Pages: 368
  • Publisher: 化学同人
• [Book] 臨床雑誌内科 124巻6号、「神経内分泌腫瘍」 (2019)
  • Author(s): 鈴木佐和子, 横手幸太郎
  • Total Pages: 170
  • Publisher: 南江堂
• [Book] 実験医学 Vol.37 No.11、「細胞老化維持機構と創薬」 (2019)
  • Author(s): 城村由和、大森徳貴、中西真
  • Total Pages: 145
  • Publisher: 羊土社
• [Book] 医学のあゆみ第271巻9号、「異分野先端技術融合による薬剤抵抗性を標的とした革新的複合治療戦略の開発」 (2019)
  • Author(s): 伊藤謙治、山田泰広
  • Total Pages: 272
  • Publisher: 医歯薬出版株式会社
• [Book] 研究年報 第30集 2019 Annual Report of the Japan Epilepsy Research Foundation (2019)
  • Author(s): 大内田守, 真下知士, 豊國伸哉, 大守伊織
  • Total Pages: 149
  • Publisher: 公益財団法人てんかん治療研究振興財団
• [Book] 医学のあゆみ 271巻2号、腫瘍免疫研究の最近の進歩、「シングルセル解析による抗腫瘍免疫応答の解明」 (2019)
  • Author(s): 大多茂樹、河上裕
  • Total Pages: 70
  • Publisher: 医歯薬出版株式会社
• [Remarks] 北海道大学大学院薬学研究院生化学研究室ホームページ
  • URL: http://www.pharm.hokudai.ac.jp/seika/index.html
• [Remarks] 北海道大学遺伝子病制御研究所分子腫瘍分野ホームページ
  • URL: http://www.igm.hokudai.ac.jp/oncology/
• [Remarks] 福島県立医科大学研究成果情報ページ
  • URL: https://www.fmu.ac.jp/univ/kenkyuseika/research/1709.html
• [Remarks] 筑波大学 医学医療系 生命医科学域 解剖学・神経科学研究室
  • URL: http://www.kansei.tsukuba.ac.jp/~takeilab/
• [Remarks] 理化学研究所RNAシステム生化学研究室 岩崎研究室ホームページ
  • URL: http://iwasakirna.com/
• [Remarks] 千葉大学大学院医学研究院 内分泌代謝・血液・老年内科学ホームページ
  • URL: https://www.m.chiba-u.ac.jp/dept/clin-cellbiol/research/diabetic/study_05/
• [Remarks] 千葉大学大学院医学研究院 内分泌代謝・血液・老年内科学ホームページ
  • URL: https://www.m.chiba-u.ac.jp/dept/clin-cellbiol/research/diabetic/study_04/
• [Remarks] 東京工業大学生命理工学院 一瀬研究室ホームページ
  • URL: http://www.bh4.bio.titech.ac.jp/index.html
• [Remarks] 東京慈恵会医科大学 総合医科学研究センター渡部研究部ホームページ
  • URL: http://watabe-lab.jp/
• [Remarks] 東京農工大学大学院工学研究院応用化学分野 大栗研究室ホームページ
  • URL: http://web.tuat.ac.jp/~h_oguri/index.html
• [Remarks] 公益財団法人微生物化学研究所
  • URL: https://www.bikaken.or.jp
• [Remarks] 慶應義塾大学薬学部生化学講座ホームページ
  • URL: http://square.umin.ac.jp/keio-dbc/research.html
• [Remarks] 順天堂大学 医学部 小松雅明研究室ホームページ
  • URL: https://www.juntendo.ac.jp/graduate/laboratory/labo/kikan_saibou/
• [Remarks] 新学術領域研究マルチモードオートファジーホームページ
  • URL: http://proteolysis.jp/multimode_autophagy/
• [Remarks] 新潟大学脳研究所 動物資源開発研究分野 ホームページ
  • URL: http://www.bri.niigata-u.ac.jp/field/lab_animal/index.html
• [Remarks] 新潟大学脳研究所 脳研コラム ホームページ
  • URL: http://www.bri.niigata-u.ac.jp/result/lab_animal/000126.html
• [Remarks] 新潟大学脳研究所 研究成果・実績 ホームページ
  • URL: http://www.bri.niigata-u.ac.jp/result/lab_animal/000833.html
• [Remarks] 新潟大学大学院医歯学総合研究科機能制御学分野のホームページ
  • URL: https://www.med.niigata-u.ac.jp/mit/
• [Remarks] 新潟大学脳研究所 研究業績ホームページ
  • URL: http://www.bri.niigata-u.ac.jp/result/surgery/001033.html
• [Remarks] 富山大学薬学部分子神経生物学研究室ホームページ
  • URL: http://www.pha.u-toyama.ac.jp/biochel/index-j.html
• [Remarks] 金沢大学広報ホームページ
  • URL: https://www.kanazawa-u.ac.jp/latest-research/64909
• [Remarks] 名古屋大学大学院医学系研究科統合生理学ホームページ
  • URL: https://www.med.nagoya-u.ac.jp/physio12/
• [Remarks] 基礎生物学研究所神経細胞生物学研究室ホームページ
  • URL: http://www.nibb.ac.jp/neurocel/index.html
• [Remarks] 自然科学研究機構 生理学研究所 細胞構造研究部門古瀬研究室ホームページ
  • URL: http://www.nips.ac.jp/dcs/
• [Remarks] 愛知県がんセンター研究所腫瘍制御学分野ホームページ
  • URL: http://www.pref.aichi.jp/cancer-center/ri/01bumon/06shuyo_uirusu/
• [Remarks] 名古屋市立大学分子毒性学分野ホームページ
  • URL: http://www.med.nagoya-cu.ac.jp/moltox.dir/
• [Remarks] 滋賀医科大学分子病態生化学ホームページ
  • URL: http://www.shiga-med.ac.jp/~hqbioch2/
• [Remarks] 京都大学上杉志成研究室
  • URL: https://www.scl.kyoto-u.ac.jp/~uesugi/ja/index.php
• [Remarks] 大阪大学大学院医学系研究科疾患データサイエンス学共同研究講座ホームページ
  • URL: https://www2.med.osaka-u.ac.jp/mds/
• [Remarks] 大阪大学微生物病研究所分子免疫制御分野 山崎研究室ホームページ
  • URL: http://molimm.biken.osaka-u.ac.jp
• [Remarks] 大阪市立大学大学院医学研究科分子病態学研究室ホームページ
  • URL: http://osaka-cu-lseika.umin.jp/
• [Remarks] 関西医科大学
  • URL: http://www.kmu.ac.jp/faculty/medical/category2/unit4.html
• [Remarks] 岡山大学大学院ヘルスシステム統合科学研究科ナノバイオシステム分子設計学ホームページ
  • URL: http://www.cyber.biotech.okayama-u.ac.jp/senolab/
• [Remarks] 広島大学 神経生理学ホームページ
  • URL: https://home.hiroshima-u.ac.jp/physio12/index.html
• [Remarks] 香川大学医学部薬理学研究室ホームページ
  • URL: http://www.kms.ac.jp/~yakuri/
• [Remarks] 九州大学生体防御医学研究所 分子医科学分野 ホームページ
  • URL: http://www.bioreg.kyushu-u.ac.jp/saibou/index.html
• [Remarks] 九州大学大学院薬学研究院 創薬腫瘍科学講座ホームページ
  • URL: http://shuyo.phar.kyushu-u.ac.jp/
• [Remarks] 福岡大学てんかん分子病態研究所ホームページ
  • URL: http://www.med.fukuoka-u.ac.jp/epilepsy/index.html
• [Remarks] 熊本大学発生医学研究所脳発生分野ホームページ
  • URL: http://www.imeg.kumamoto-u.ac.jp/bunya_top/brain_morphogenesis/
• [Remarks] 熊本大学国際先端医学研究所ホームページpublication欄
  • URL: http://ircms.kumamoto-u.ac.jp/publications/2017/01/identification-of-stem-cells-in-the-epithelium-of-the-stomach-corpus-and-antrum-of-mice.html
• [Remarks] 可変型遺伝子トラップクローンデータベース(EGTC)
  • URL: http://egtc.jp
• [Remarks] 鹿児島大学大学院医歯学総合研究科分子腫瘍学分野ホームページ
  • URL: http://www.kufm.kagoshima-u.ac.jp/~molonc12/
• [Remarks] 東北大学医化学分野ホームページ
  • URL: http://www.dmbc.med.tohoku.ac.jp/official/index.html
• [Remarks] 筑波大学 生命環境系 中田・石川研 HP
  • URL: http://www.biol.tsukuba.ac.jp/nakada_ishikawa/index.html
• [Remarks] 東京大学大学院薬学系研究科 井上将行研究室ホームページ
  • URL: http://www.f.u-tokyo.ac.jp/~inoue/
• [Remarks] 東京理科大学 生命医科学研究所 昆俊亮研究室ホームページ
  • URL: https://konshunsukelab.wixsite.com/rs-tus
• [Remarks] 新潟大学医歯学系神経生化学(生化学第二)HP
  • URL: https://www.med.niigata-u.ac.jp/bc2/index.html
• [Remarks] 京都大学 農学研究科 生命有機化学研究室ホームページ
  • URL: http://www.orgchem.kais.kyoto-u.ac.jp/
• [Remarks] 文部科学省科学研究費新学術領域研究 先端モデル動物支援プラットフォーム
  • URL: http://model.umin.jp/index.html
• [Remarks] 北海道大学青沼研究室ホームページ
  • URL: http://ncmac2.es.hokudai.ac.jp/index.html
• [Remarks] 東京医学歯科大学ホームページ(プレスリリース)
  • URL: http://www.tmd.ac.jp/press-release/20180213_1/index.html
• [Remarks] 東京医学歯科大学ホームページ(プレスリリース)
  • URL: http://www.tmd.ac.jp/english/press-release/20180319_1/index.html
• [Remarks] 金沢大学 学際科学実験センターニュース 第16号 2019.2 p6 金沢大学がん進展制御研究室腫瘍分子生物学研究分野ホームページ
  • URL: http://omb.w3.kanazawa-u.ac.jp/index.html
• [Remarks] 新潟大学オートファジー、代謝と神経変性疾患ホームページ
  • URL: https://www.med.niigata-u.ac.jp/bcl/A3/index.html
• [Remarks] 名古屋大学 環境医学研究所 神経系分野ホームページ
  • URL: http://www.riem.nagoya-u.ac.jp/4/drofl/nr/
• [Remarks] 大阪大学分子病態生化学研究室ホームページ
  • URL: http://www.med.osaka-u.ac.jp/pub/molbiobc/index.html
• [Remarks] 京都大学小川正晃研究室ホームページ
  • URL: https://sites.google.com/view/ogawagroup/
• [Remarks] 京都大学老化とアンチエイジング研究室ホームページ
  • URL: http://www.anti-aging.jpn.com/
• [Remarks] FNN PRIME 2020/2/7 不妊原因に関わる新しい遺伝子を発見 熊本大学発生医学研究所が世界初の快拳!
  • URL: https://www.fnn.jp/posts/2363TKU/202002071931_TKU_TKU
• [Remarks] 大学ジャーナルオンライン 「卵子・精子を作る減数分裂をコントロールする遺伝子の発見 熊本大学」
  • URL: https://univ-journal.jp/30557/
• [Remarks] テレビ朝日ANN news 2020/2/7
  • URL: https://news.tv-asahi.co.jp/news_society/articles/000175676.html
• [Remarks] 熊本日日新聞 2020/2/7 不妊防ぐ遺伝子特定 治療進展に期待 熊本大・石黒准教授ら
  • URL: https://kumanichi.com/kumacole/interest/1348652/
• [Remarks] 時事通信(JIJI.COM) 2020/2/7 精子、卵子形成に必須遺伝子 減数分裂のスイッチー熊本大など
  • URL: https://www.jiji.com/jc/article?k=2020020700066&g=soc
• [Remarks] 熊本大学HP プレスリリース
  • URL: https://www.kumamoto-u.ac.jp/whatsnew/seimei/20200206
• [Remarks] 熊本大学発生医学研究所HP
  • URL: http://www.imeg.kumamoto-u.ac.jp/en/np91/
• [Remarks] 熊本大学発生医学研究所HP
  • URL: http://www.imeg.kumamoto-u.ac.jp/np104/
• [Remarks] 西日本新聞 2020/2/7 妊娠左右する遺伝子発見 熊本大など、不妊治療への応用期待
  • URL: https://www.nishinippon.co.jp/item/n/582155/
• [Remarks] 朝日新聞2020/2/19 不妊に関わる遺伝子を発見 熊本大など、マウス実験で
  • URL: https://www.asahi.com/articles/DA3S14370621.html
• [Remarks] 日刊工業新聞2020/2/7 熊本大、生殖細胞の形成遺伝子発見 不妊治療など応用期待
  • URL: https://www.nikkan.co.jp/spaces/view/0051656
• [Remarks] テレビ朝日ANN news 2020/2/7 世界初“不妊”の遺伝子特定 治療の発展に期待
  • URL: https://news.tv-asahi.co.jp/news_society/articles/000175676.html
• [Remarks] 日本糖尿病学会ホームページ きらり女性医師
  • URL: http://www.jds.or.jp/modules/education/index.php?content_id=19
• [Remarks]
• [Patent(Industrial Property Rights)] がんを治療するための組み合わせ物及び医薬組成物 (2020)
  • Inventor(s): 長澤和夫、松田未沙子、馬悦、清宮啓之
  • Industrial Property Rights Holder: 国立大学法人東京農工大学、公益財団法人がん研究会
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 特願2020-008592
• [Patent(Industrial Property Rights)] グアニン四重鎖結合性リガンド (2020)
  • Inventor(s): 長澤和夫、馬悦
  • Industrial Property Rights Holder: 東京農工大学
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 特願2020-021316
• [Patent(Industrial Property Rights)] DNA配列の増幅方法及び配列決定方法 (2019)
  • Inventor(s): 斎藤益満、百瀬暖佳、松平崇弘、和田悠作
  • Industrial Property Rights Holder: 日本国、株式会社ファスマック
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 特願2019-150535
• [Patent(Industrial Property Rights)] 抗がん剤 (2019)
  • Inventor(s): 長澤和夫、松田未沙子、馬悦、清宮啓之
  • Industrial Property Rights Holder: 国立大学法人東京農工大学、公益財団法人がん研究会
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: PCT/JP2019/028398
  • Overseas
• [Patent(Industrial Property Rights)] 新規ジヒドロイソキノリノン系化合物又はその薬理学的に許容される塩 (2019)
  • Inventor(s): 吉田稔、八代田陽子、白井文幸、風見純一、清宮啓之
  • Industrial Property Rights Holder: 国立研究開発法人理化学研究所、公益財団法人 がん研
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 特願2019-118938
• [Patent(Industrial Property Rights)] マウスMAIT様細胞及びMAIT細胞豊富なマウス (2019)
  • Inventor(s): 若尾 宏, 杉本 智恵
  • Industrial Property Rights Holder: 獨協医科大学
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 特願2019-196603
• [Patent(Industrial Property Rights)] テトラヒドロイソキノリン環含有化合物の製造方法 (2019)
  • Inventor(s): 大栗博毅(東京農工大)、谷藤涼(東京農工大)、及川英秋(北海道
  • Industrial Property Rights Holder: 大栗博毅(東京農工大)、谷藤涼(東京農工大)、及川英秋(北海道
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: PCT/JP2019/009128
  • Overseas
• [Patent(Industrial Property Rights)] パーキンソン病の診断指標 (2019)
  • Inventor(s): 山本 融、正木 勉、出口一志、鎌田正紀、高田忠幸、國土曜平
  • Industrial Property Rights Holder: 香川大学・北海道大学
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 特願2019-033661
• [Patent(Industrial Property Rights)] 遺伝子改変非ヒトモデル動物 (2019)
  • Inventor(s): 大守伊織, 大内田守, 真下知士
  • Industrial Property Rights Holder: 大守伊織, 大内田守, 真下知士
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 特願2019-514326
• [Patent(Industrial Property Rights)] 炎症レボーターシステム (2019)
  • Inventor(s): 山村研一、岩脇隆夫、及川大輔、石川智夫
  • Industrial Property Rights Holder: 株式会社トランスジェニック
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 6472448