先端モデル動物支援プラットフォーム

2020 Fiscal Year Annual Research Report

• Project/Area Number: 16H06276
• Research Institution: The University of Tokyo
• Principal Investigator: 井上 純一郎 東京大学, 医科学研究所, 特任研究員
• Project Period (FY): 2016 – 2021
• Keywords: モデル動物作製 / ゲノム編集 / 病理形態解析 / 生理機能解析 / 分子探索・プロファイリング

Outline of Annual Research Achievements

①総括支援活動 : 若手技術講習会を9月11日にオンラインにて開催した。108名の参加者があり、活発な討論が行われた。成果発表会は2月2日にハイブリッド形式で開催し、被支援者による研究成果の紹介を中心に行われ252名の参加者があった。支援拠点の研究者と被支援者が分担で執筆した本支援活動を紹介する「マウス・ラットモデル作製・解析プロフェッショナル」を出版した。
②モデル動物作製支援活動 : 前・後期2回の公募で申請のあった計116件について一次・二次審査を行い、学術的に優れた83件の申請を採択した。それぞれの採択者と個別に協議し、最適な遺伝子改変技術を用いて、遺伝子改変マウスおよびラットを迅速に作製し、研究リソースとして提供した。
③病理形態解析支援活動 : 55件の申請を受け、3回の審査の結果、35件に関して病理形態解析を実施した。研究の方向性を裏付ける多くの成果が得られた。論文の図の作成など、論文が受理されるまで支援を実施した。
④生理機能解析支援活動 : 行動学的解析では26件、薬理学的解析では16件、光技術による操作解析では9件、多機能電極・計測データ解析では13件の申請について支援し、コロナ禍にもかかわらず、4つの支援の全てで、昨年度よりも支援数を増やした。支援は、動物モデルにおける病態・生理学的基盤の解明推進などに寄与し、Nat Commun誌、iScience誌などに成果が発表された。
⑤分子プロファイリング支援活動 : 化合物の分子プロファイリング48件、阻害剤キット配付18件、RNA干渉キット配付・siRNAデザイン合成5件、shRNAライブラリー探索2件、分子間相互作用解析1件(計74件、支援提供回数として505回)に加え、高次情報解析、動物実験に向けた技術相談を行った。被支援者と全班員の意見交換を目的としたユーザー会議を開催した。

Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

①総括支援活動 : 今年度はコロナ禍にもかかわらず、若手技術講習会をオンライン開催で、成果発表会をハイブリッド開催で実施することができ、反響も大きかった。また、広報活動の一層の充実を目的として、支援拠点のメンバーによる出版企画を実施することができた。
②モデル動物作製支援活動 : 研究実施計画に沿った支援を行うことができている。コロナ禍にあっても、リモート会議を活用した綿密な打ち合わせを実施した。また、最新技術を導入するとともに、支援拠点で開発されたリソースおよび技術を活用し、効率的な遺伝子改変を行った。さらに、動物受け入れが困難な施設については、支援拠点で凍結胚を作製し、一時保管を行った。
③病理形態解析支援活動 : 申請数は増加しており、事前相談や再審査によりできるだけ多く若手研究者の支援を行うよう努力している。現在の予算ならびに班員のエフォートにおいてできる最大限の支援活動を実施しており、成果は確実に上がっている。今年度は、支援結果の議論にウェブ会議も使用した。
④生理機能解析支援活動 : 支援対象者のモデルマウスを対象にした「網羅的行動テストバッテリー」を用いた行動解析支援を26件、依存性薬物等の感受性に関連する行動解析および規制薬物作用ゲノム関連解析支援を16件、進展著しい光遺伝学に関する最新技術を活用した研究支援を9件、多機能集積化電極による最先端の技術提供を行う多元的生理機能計測操作支援を13件で実施した。
⑤分子プロファイリング支援活動 : コロナ禍の影響が危ぶまれたが、被支援者との事前打ち合わせや日程の弾力的調整により、円滑な支援体制を維持することができた。本年度は被支援者の研究室の若手も含めた技術指導、動物実験・論文構想・特許出願などに関する助言を強化し、多くの案件が共同研究に進展した。寄託化合物ライブラリー支援により、被支援者間の異分野共同研究斡旋にも成果があった。

Strategy for Future Research Activity

①総括支援活動 : WEBを利用した講習会や発表会の内容の向上を図る。特にディスカッションが一層推進されることを目指す。広報活動として、「マウス・ラットモデル作製・解析プロフェッショナル」の紹介に力をいれ、若手研究者に本支援活動をより理解してもらうよう努める。
②モデル動物作製支援活動 : 先端的な遺伝子改変技術の導入および開発とともに、支援拠点が持つ独自のリソース活用することにより、科研費により進められる学術研究を支援する。学術的な価値や成功時の波及効果の高い支援課題については、より高度なリソースの開発・提供を行う。作製された遺伝子改変動物は、公共リソースバンクに供出し、学術基盤としての研究リソースの整備を推進する。
③病理形態解析支援活動 : 現在、予算ならびに班員のエフォートに関して限界に近い状態となっている。今後は審査をより厳格に行うが、少額研究費の若手の申請に特に対応したいと考えている。基本姿勢が、一旦開始した病理形態支援は論文が受理されるまでサポートするという方針に変化はない。
④生理機能解析支援活動 : 5つの拠点への支援申請が何れも安定して多数であるとともに増加していることから、引き続きニーズに応えられるように拠点における技術力を維持・向上させ、公正に支援課題を選考し、支援実施体制をハイレベルに保つ。また、技術支援にとどまらず、支援該当部の論文分担執筆を積極的に進め、成果の公表にも貢献する。
⑤分子プロファイリング支援活動 : 前年度に引き続き、被支援者の要望に応じた解析条件のカスタマイズ対応・支援実施後のフォロー(科学的助言・技術指導、高次支援の勧奨)に努めるとともに、定例班会議とユーザーミーティングで課題を共有し、効果的な共同研究の提案・斡旋を行う。モデル動物研究の起点的役割を担う当班の6年間の実績を俯瞰し、次代の生命科学を牽引する新しい支援の枠組みを提案する。

Research Products

• [Int'l Joint Research] Johns Hopkins University/Medical University of South Crolina/Van Andel Resarch Institute(米国)
  • Country Name: U.S.A.
  • Counterpart Institution: Johns Hopkins University/Medical University of South Crolina/Van Andel Resarch Institute
  • # of Other Institutions: 2
• [Int'l Joint Research] University of Western Ontario(カナダ)
  • Country Name: CANADA
  • Counterpart Institution: University of Western Ontario
• [Int'l Joint Research] Université Claude Bernard Lyonl(フランス)
  • Country Name: FRANCE
  • Counterpart Institution: Université Claude Bernard Lyonl
• [Int'l Joint Research] Beijing University of Technology(シンガポール)
  • Country Name: SINGAPORE
  • Counterpart Institution: Beijing University of Technology
• [Int'l Joint Research] Beijing University of Technology/南通大学(中国)
  • Country Name: CHINA
  • Counterpart Institution: Beijing University of Technology/南通大学
• [Int'l Joint Research]
  • # of Other Countries: 4
• [Journal Article] Application of Optogenetics for Muscle Cells and Stem Cells. (2021)
  • Author(s): Asano T, Teh DBL, Yawo H.
  • Journal Title: Adv Exp Med Biol. Volume: 1293 Pages: 359-375
  • DOI: 10.1007/978-981-15-8763-4_23
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Arf1 and Arf6 Synergistically Maintain Survival of T Cells during Activation (2021)
  • Author(s): M. Sumiyoshi, Y. Kotani, Y. Ikuta, K. Suzue, M. Ozawa, T. Katakai, T. Yamada, T. Abe, K. Bando, S. Koyasu, Y. Kanaho, T. Watanabe and S. Matsuda
  • Journal Title: The Journal of Immunology Volume: 206 Pages: 366-375
  • DOI: 10.4049/jimmunol.2000971
  • Peer Reviewed
• [Journal Article] Association of urinary free cortisol with bone formation in patients with mild autonomous cortisol secretion. (2021)
  • Author(s): Ishida A, Igarashi K, Ruike Y, Ishiwata K, Naito K, Kono S, Deguchi H, Fujimoto M, Shiga A, Suzuki S, Yoshida T, Tanaka T, Tatsuno I, Yokote K, Koide H.
  • Journal Title: Cl in Endocrinol (Oxf). Volume: 94 Pages: 544-550
  • DOI: 10.1111/cen.14385.Epub 2020 Dec 17
  • Peer Reviewed / Open Access
• [Journal Article] Behavioral consequences of a combination of Gadl Haplodeficiency and adolescent exposure to NMDA receptor antagonist in Long-Evans rat. (2021)
  • Author(s): Fujihara K, Sato T, Higeta K, Miyasaka Y, Mashimo T, Yanagawa Y.
  • Journal Title: Front Pharmacol. Volume: 12 Pages: 646088
  • DOI: 10.3389/fphar.2021.646088
  • Peer Reviewed / Open Access
• [Journal Article] Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice (2021)
  • Author(s): Yoshida T, Yamagata A, Imai A, Kim J, Izumi H, Maenaka K, Shimada T, Fukata M, Nishijo H, Takao K, Okabe S, Tabuchi K, Mishina M, Mori H, Fukai S.
  • Journal Title: Nature Communications Volume: 12 Issue: 1 Pages: 1848
  • DOI: 10.1038/s41467-021-22059-6
  • Peer Reviewed / Open Access
• [Journal Article] Chondroitin Sulfate N-acetylgalactosaminyltransferase-2 Impacts Foam Cell Formation and Atherosclerosis by Altering Macrophage Glycosaminoglycan Chain (2021)
  • Author(s): Adhikara IM, Yagi K, Mayasari DS, Suzuki Y, Ikeda K, Ryanto GRT, Sasaki N, Rikitake Y, Nadanaka S, Kitagawa H, Miyata O, Igarashi M, Hirata K, Emoto N
  • Journal Title: Arterioscler Thromb Vasc Biol Volume: 41 Issue: 3 Pages: 1076-1091
  • DOI: 10.1161/ATVBAHA.120.315789
  • Peer Reviewed
• [Journal Article] Concise synthesis and in vitro anticancer activity of benzo[g][1]benzopyrano[4, 3-b]indol-6(13H)-ones (BBPIs), topoisomerase I inhibitors based on the marine alkaloid lamellarin (2021)
  • Author(s): Fumito Ishibashi, Tsutomu Fukuda, Shijiao Zha, Aya Hashirano, Shotaro Hirao, Masatomo Iwao
  • Journal Title: Bioscience, Biotechnology, and Biochemistry Volume: 85 Pages: 181-191
  • DOI: 10.1093/bbb/zbaa028
  • Peer Reviewed
• [Journal Article] Constitutive increase of IL-17A in serum affects microglial activity in the hippocampal dentate gyrus. (2021)
  • Author(s): Sasaki T, Takei Y.
  • Journal Title: Jap J Biol Psych. Volume: 32 Issue: 2
  • Peer Reviewed / Open Access
• [Journal Article] Design and synthesis of 14 and 15-membered macrocyclic scaffolds exhibiting inhibitory activities of hypoxia-inducible factor 1α. (2021)
  • Author(s): Shimizu T, Takahashi N, Huber VJ, Asawa Y, Ueda H, Yoshimori A, Muramatsu Y, Seimiya H, Kouji H, Nakamura H, Oguri H.
  • Journal Title: Bioorg Med Chem. Volume: 30 Pages: 115949
  • DOI: 10.1016/j.bmc.2020.115949
  • Peer Reviewed
• [Journal Article] Development of a label-free ATP image sensor for analyzing spatiotemporal patterns of ATP release from biological tissues (2021)
  • Author(s): Doi H, Parajuli B, Horio T, Shigetomi E, Shinozaki Y, Noda T, Takahashi K, Hattori T, Koizumi S, Sawada K
  • Journal Title: Sensors and Actuators B : Chemical Volume: 335 Pages: 129686
  • DOI: 10.1016/j.snb.2021.129686
  • Peer Reviewed
• [Journal Article] Differences between a therosclerotic and non-atherosclerotic patients in expression levels of inflammatory mediators in the adipose tissue around the coronary artery. (2021)
  • Author(s): Suzuki T, Ogita H, Sato A, Minamidate N, Hachiro K.
  • Journal Title: Int Heart J
  • DOI: 10.1536/ihj.20-585
  • Peer Reviewed
• [Journal Article] Distinct effects of chondroitin sulfate on hematopoietic cells and the stromal microenvironment in bone marrow hematopoiesis. (2021)
  • Author(s): Katagiri T, Ushiki T, Nakajima-Takagi Y, Oshima M, Mikami T, Kawasaki A, Ishiguro H, Tanaka T, Sone H, Kitagawa H, Igarashi M, Iwama A, Masuko M
  • Journal Title: Exp Hematol Volume: 96 Pages: 52-62
  • DOI: 10.1016/j.exphem.2021.02.003
  • Peer Reviewed
• [Journal Article] Divergent Total Synthesis of Azalamellarins D and N (2021)
  • Author(s): Tsutomu Fukuda, Seiya Okutani, Mayu Sumi, Kazuhito Miyagi, Gen Onodera, Masanari Kimura
  • Journal Title: Heterocycles Volume: 103
  • DOI: 10.3987/COM-20-S(K)53
  • Peer Reviewed
• [Journal Article] Dopamine D2 Long Receptors Are Critical for Caveolae-Mediated α-Synuclein Uptake in Cultured Dopaminergic Neurons. (2021)
  • Author(s): Kawahata I, Sekimori T, Wang H, Wang Y, Sasaoka T, Bousset L, Melki R, Mizobata T, Kawata Y, Fukunaga K.
  • Journal Title: Biomedicines Volume: 9 Issue: 1 Pages: E49
  • DOI: 10.3390/biomedicines9010049
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Dysfunction of the proteoglycan Tsukushi causes hydrocephalus through altered neurogenesis in the subventricular zone in mice. (2021)
  • Author(s): Ito, N., Riyadh, M., Ahmad, S., Hattori, S., Miyakawa, T. and Ohta, K., et al.
  • Journal Title: Science Translational Medicine Volume: 13 Issue: 587 Pages: eaay7896
  • DOI: 10.1126/scitranslmed.aay7896
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Effects of RORγt overexpression on the murine central nervous system. (2021)
  • Author(s): Sasaki T, Nagata R, Takahashi S, Takei Y
  • Journal Title: Neuropsychopharmacology Reports Pages: 1-9
  • DOI: 10.1111/NPR2.12162
  • Peer Reviewed / Open Access
• [Journal Article] Fhod3 Controls the Dendritic Spine Morphology of Specific Subpopulations of Pyramidal Neurons in the Mouse Cerebral Cortex (2021)
  • Author(s): Hikmawan Wahyu Sulistomo, Takayuki Nemoto, Yohko Kage, Hajime Fujii, Taku Uchida, Kogo Takamiya, Hideki Sumimoto, Hiroaki Kataoka, Haruhiko Bito, Ryu Takeya
  • Journal Title: Cerebral Cortex
  • DOI: 10.1093/cercor/bhaa355
  • Peer Reviewed
• [Journal Article] Genetic deletion of the 67-kDa isoform of glutamate decarboxylase alters conditioned fear behavior in rats. (2021)
  • Author(s): Fujihara K, Sato T, Miyasaka Y, Mashimo T, Yanagawa Y.
  • Journal Title: FEBS Open Bio.
  • DOI: 10.1002/2211-5463.13065
  • Peer Reviewed / Open Access
• [Journal Article] Genetic implications in quality palliative care and preventing opioid crisis in cancer-related pain management. (2021)
  • Author(s): Sumitani M, Nishizawa D, Hozumi J, Ikeda K.
  • Journal Title: Journal of Neuroscience Research
  • DOI: 10.1002/jnr.24756
  • Peer Reviewed
• [Journal Article] GLI3 is associated with neuronal differentiation in SHH-activated and WNT-activated medulloblastoma (2021)
  • Author(s): Natsumeda M, Miyahara H, Yoshimura J, Okada M, Hirato J, Wataya T, Tateishi K, Rodriguez FJ, Suva ML, Taylor MD, Eberhart CG, Fujii Y, Kakita A
  • Journal Title: Journal of Neuropathology and Experimental Neurology Volume: 80 Issue: 2 Pages: 129-136
  • DOI: 10.1093/jnen/nlaa141
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Global knockdown of glutamate decarboxylase 67 elicits emotional abnormality in mice. (2021)
  • Author(s): Miyata S, Kakizaki T, Fujihara K, Obinata H, Hirano T, Nakai J, Tanaka M, Itohara S, Watanabe M, Tanaka KF, Abe M, Sakimura K, Yanagawa Y.
  • Journal Title: Mol Brain. Volume: 14 Pages: 5
  • DOI: 10.1186/s13041-020-00713-2
  • Peer Reviewed / Open Access
• [Journal Article] G-quadruplex-forming nucleic acids interact with SF3B2 and suppress innate immune gene expression. (2021)
  • Author(s): Matsumoto K, Okamoto K, Okabe S, Fujii R, Ueda K, Ohashi K, Seimiya H.
  • Journal Title: Genes Cells Volume: 26 Pages: 65-82
  • DOI: 10.1111/gtc.12824
  • Peer Reviewed / Open Access
• [Journal Article] His-Cytoglobin Deactivates Hepatic Stellate Cells and Inhibits Liver Fibrosis by Scavenging Reactive Oxygen Species. (2021)
  • Author(s): Dat NQ, Oikawa D, Yoishizato K, Tokunaga F, Pinzani M, Kawada M, et al.
  • Journal Title: Hepatology.
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] ICAM1-Negative Intravascular Large B-Cell Lymphoma of the Pituitary Gland : A Case Report and Literature Review. (2021)
  • Author(s): Kumiko Naito, Sawako Suzuki, Chikako Ohwada, Jun-ichiro Ikeda, Tomoaki Tanaka, Koutaro Yokote.
  • Journal Title: AACE Clinical Case Reports
  • DOI: 10.1016/j.aace.2021.01.011
  • Peer Reviewed / Open Access
• [Journal Article] Induced genetic ablation of Rest leads to the alteration of stimulus-induced response of the vagal nerve. (2021)
  • Author(s): Aoki H, Abe C, Hara A, Miyazaki T, Morita H, Kunisada T.
  • Journal Title: Genes Cells. Volume: 26 Issue: 2 Pages: 45-55.
  • DOI: 10.1111/gtc.12819
  • Peer Reviewed
• [Journal Article] Kvll (ether-â-go-go-related gene) voltage-dependent K+ channels promote resonance and oscillation of subthreshold membrane potentials (2021)
  • Author(s): Toshinori Matsuoka, Miwako Yamasaki, Manabu Abe, Yukiko Matsuda, Hiroyuki Morino, Hideshi Kawakami, Kenji Sakimura, Masahiko Watanabe, Kouichi Hashimoto
  • Journal Title: Journal of Physiology (London) Volume: 599 Pages: 547-569
  • DOI: 10.1113/JP280342
  • Peer Reviewed / Open Access
• [Journal Article] Lamellarin 14, a derivative of marine alkaloids, inhibits the T790M/C797S mutant epidermal growth factor receptor (2021)
  • Author(s): Nishiya N, Oku Y, Ishikawa C, Fukuda T, Dan S, Mashima T, Ushijima M, Matsuura M, Tomida A, Seimiya H, Yamori T, Iwao M, Uehara Y, et al.
  • Journal Title: Cancer Sci.
  • DOI: 10.1111/cas.14839
  • Peer Reviewed / Open Access
• [Journal Article] MEK inhibition preferentially suppresses anchorage-independent growth in osteosarcoma cells and decreases tumors in vivo (2021)
  • Author(s): T Shimizu, K Kimura, E Sugihara, S Yamaguchi - Iwai, H Nobusue, O Sampetrean, Y Otsuki, Y Fukuchi, K Saitoh, K Kato, T Soga, A Muto, H Saya
  • Journal Title: Journal of Orthopaedic Research
  • DOI: 10.1002/jor.25023
  • Peer Reviewed
• [Journal Article] Mice with a cleavage-resistant N-cadherin exhibit synapse anomaly in the hippocampus and outperformance in spatial memory tasks (2021)
  • Author(s): Asada-Utsugi M, Uemura K, Noda Y, 他8名, Takahashi R, Hattori S, Miyakawa T, Ageta-Ishihara N, Kobayashi K, Kinoshita M, Kinoshita A.
  • Journal Title: Molecular Brain Volume: 14 Issue: 1 Pages: 23
  • DOI: 10.1186/s13041-021-00738-1
  • Peer Reviewed / Open Access
• [Journal Article] Mice with mutations in Trpml, a gene within the locus of 15q13.3 microdeletion syndrome, display pronounced hyperactivity and decreased anxiety-like behavior. (2021)
  • Author(s): Tesshu Hori, Shohei Ikuta, Satoko Hattori, Keizo Takao, Tsuyoshi Miyakawa, Chieko Koike
  • Journal Title: Molecular Brain Volume: 14 Issue: 1 Pages: 61
  • DOI: 10.1186/s13041-021-00749-y
  • Peer Reviewed / Open Access
• [Journal Article] Multimodal Functional Analysis Platform : 4. Optogenetics-Induced Oscillatory Activation to Explore Neural Circuits (2021)
  • Author(s): Mushiake H, Ohshiro T, Osawa SI, Hosaka R, Katayama N, Tanaka T, Yawo H, Osanai M.
  • Journal Title: Adv Exp Med Biol. Volume: 1293 Pages: 501-509
  • DOI: 10.1007/978-981-15-8763-4_34
  • Peer Reviewed
• [Journal Article] Murine neonatal ketogenesis preserves mitochondrial energetics by preventing protein hyperacetylation (2021)
  • Author(s): Arima Y, Nakagawa Y, Takeo T, Ishida T, Yamada T, Hino S, Yamagata K, Nakamura T, Nakagata N, Tsujita K
  • Journal Title: Nature Metabolism Volume: 3 Pages: 196-210
  • DOI: 10.1038/s42255-021-00342-6
  • Peer Reviewed
• [Journal Article] Neuromodulatory effect of interleukin 1 in the dorsal raphe nucleus on individual differences in aggression (2021)
  • Author(s): Aki Takahashi, Hossein Aleyasin, Tetsuya Sasaki, Sonoko Ogawa, Bruce S. McEwen and Scott J. Russo, et al
  • Journal Title: Molecular Psychiatry
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Neuronal degeneration and cognitive impairment can be prevented via the normalization of mitochondrial dynamics (2021)
  • Author(s): Ishikawa K, Yamamoto S, Hattori S, Nishimura N, Matsumoto H, Miyakawa T, Nakada K.
  • Journal Title: Pharmacol Res. Volume: 163 Pages: 105246
  • DOI: 10.1016/j.phrs.2020.105246
  • Peer Reviewed
• [Journal Article] Ni-catalyzed direct carboxylation of propargylic alcohols with carbon dioxide (2021)
  • Author(s): Tatsuya Yamahira, Gen Onodera, Tsutomu Fukuda, Masanari Kimura
  • Journal Title: Chemistry Letters
  • DOI: 10.1246/cl.210008
  • Peer Reviewed
• [Journal Article] Nickel-Catalyzed Carboxylation of Conjugated Dienes with Carbon Dioxide and DIBAL-H for the Synthesis of β, γ-Unsaturated Carboxylic Acids (2021)
  • Author(s): Ying Luo, Bun Chan, Tsutomu Fukuda, Gen Onodera, Masanari Kimura
  • Journal Title: Synlett
  • DOI: 10.1055/a-1336-8034
  • Peer Reviewed
• [Journal Article] Nutritional intervention for cancer sarcopenia. (2021)
  • Author(s): Mori T, Kido A, Kawahara I, Nukaga S, Miyagawa Y, Goto K, Mori S, Kishi S, Fujii K, Fujiwara-Tani R, Kuniyasu H
  • Journal Title: Ann Muscloskeletal Med Volume: 5 Issue: 1 Pages: 001-004
  • DOI: 10.17352/amm.000024
  • Peer Reviewed / Open Access
• [Journal Article] Occludin and tricellulin facilitate formation of anastomosing tight-junction strand network to improve barrier function (2021)
  • Author(s): Akira C Saito, Tomohito Higashi, Yugo Fukazawa, Tetsuhisa Otani, Masashi Tauchi, Atsuko Y Higashi, Mikio Furuse, Hideki Chiba
  • Journal Title: Molecular biology of the cell
  • DOI: 10.1091/mbc.E20-07-0464
  • Peer Reviewed
• [Journal Article] Palmitoyl piperidinopiperidine, a novel derivative of 10-hydroxy-2-decenoic acid, as a potent and selective anticancer agent against human colon carcinoma cell lines (2021)
  • Author(s): Ando S, Fukamachi K, Yoshimoto E, Matsumoto H, Iinuma M and Suzui M.
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• [Journal Article] Phosphorylation of GAP-43 T172 is a molecular marker of growing axons in a wide range of mammals including primates. (2021)
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• [Journal Article] Post-translational palmitoylation of ionotropic glutamate receptors in excitatory synaptic functions. (2021)
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• [Journal Article] Potential role of astrocytes and Muller cells in the pathogenesis of glaucoma (2021)
  • Author(s): Shinozaki Y, Koizumi S
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• [Journal Article] Prioritized experience replays on a hippocampal predictive map for learning (2021)
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• [Journal Article] Rats deficient in the GAD65 isoform exhibit epilepsy and premature lethality. (2021)
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• [Journal Article] Reactive astrocyte-driven epileptogenesis is induced by microglia initially activated following status epilepticus (2021)
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• [Journal Article] (S)-erypoegin K, an isoflavone isolated from Erythrina poeppigiana, is a novel inhibitor of topoisomerase Ⅱα : Induction of G2 phase arrest in human gastric cancer cells (2021)
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  • Journal Title: Bioorg. Med. Chem. Volume: 30 Pages: 115904
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• [Journal Article] Stomatin-mediated inhibition of the Akt signaling axis suppresses tumor growth. (2021)
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  • Journal Title: Cancer Res
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• [Journal Article] Synthesis and evaluation of azalamellarin N and its A-ring-modified analogues as non-covalent inhibitors of the EGFR T790M/L858R mutant (2021)
  • Author(s): Tsutomu Fukuda, Fumito Ishibashi, Yusuke Oku, Naoyuki Nishiya, Yoshimasa Uehara, Masatomo Iwao
  • Journal Title: Bioorganic & Medicinal Chemistry Volume: 34 Pages: 116039
  • DOI: 10.1016/j.bmc.2021.116039
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• [Journal Article] The KEAP1-NRF2 system as a molecular target of cancer treatment (2021)
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• [Journal Article] Tiny Drosophila makes giant strides in cancer research (2021)
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• [Journal Article] Total Synthesis and Biological Evaluation of Oscillatoxin D, E, and F (2021)
  • Author(s): Yusuke Araki, Yusuke Hanaki, Masaki Kita, Koutaro Hayakawa, Kazuhiro Irie, Yoshihiko Nokura, Atsuo Nakazaki, and Toshio Nishikawa
  • Journal Title: Bioscience, Biotechnology, and Biochemistry
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• [Journal Article] Transnasal transplantation of human induced pluripotent stem cell-derived microglia to the brain of immunocompetent mice. (2021)
  • Author(s): Parajuli B, Saito H, Shinozaki Y, Shigetomi E, Miwa H, Yoneda S, Tanimura M, Omachi S, Asaki T, Takahashi K, Fujita M, Nakashima K, Koizumi S
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• [Journal Article] TRIM28 Expression on Dendritic Cells Prevents Excessive T Cell Priming by Silencing Endogenous Retrovirus (2021)
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• [Journal Article] Tyrosine hydroxylase conditional knockout mice reveal peripheral tissue-dependent differences in dopamine biosynthetic pathways (2021)
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  • Journal Title: Journal of Nuclear Medicine
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• [Journal Article] 環境応答・適応の分子機構 (2021)
  • Author(s): 田口恵子、山本雅之
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  • Author(s): Shutoh F, Masuda T, Sasaki T, Takei Y.
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• [Journal Article] Neural stem cell-specific ITPA deficiency causes neural depolarization and epilepsy (2020)
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• [Journal Article] A chemical genomics-aggrephagy integrated method studying functional analysis of autophagy inducers. (2020)
  • Author(s): Kataura T, Tashiro E, Nishikawa S, Onodera M, Shin-ya K, et al, Sasazawa Y, Hattori N, Saiki S, and Imoto M
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• [Journal Article] A high-throughput detection method for the clonality of Human T-cell leukemia virus type-1-infected cells in vivo (2020)
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  • Journal Title: International Journal of Hematology Volume: 112 Issue: 3 Pages: 300-306
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• [Journal Article] A Human DUB Protein Array for Clarification of Linkage Specificity of Polyubiquitin Chain and Application to Evaluation of Its Inhibitors (2020)
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• [Journal Article] A widespread family of heat-resistant obscure (Hero) proteins protect against protein instability and aggregation (2020)
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• [Journal Article] ALDH1A3-mTOR axis as a therapeutic target for anticancer drug-tolerant persister cells in gastric cancer. (2020)
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• [Journal Article] Anti-stem cell property of pterostilbene in gastrointestinal cancer cells. (2020)
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• [Journal Article] Behavioral and electrophysiological evidence for a neuroprotective role of aquaporin-4 in the 5xFAD transgenic mice model (2020)
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• [Journal Article] Cardiomyocyte Sirt (Sirt7)7 ameliorates stress-induced cardiac hypertrophy by interacting with and deacetylating GATA4 (2020)
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• [Journal Article] Complete chemical structures of human mitochondrial tRNAs (2020)
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• [Journal Article] Defective biosynthesis of ascorbic acid in Sodl-deficient mice results in lethal damage to lung tissue (2020)
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• [Journal Article] Detection of cellular G-quadruplex by using a loop structure as a structural determinant. (2020)
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• [Journal Article] Differential sensitivity to detect prosocial effects of 3,4-methylenedioxymethamphetamine (MDMA) in different social approach paradigms in mice (2020)
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• [Journal Article] Disruption of dystonin in Schwann cells results in late-onset neuropathy and sensory ataxia. (2020)
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• [Journal Article] Dynamic Axis-Tuned Cells in the Monkey Lateral Prefrontal Cortex during a Path-Planning Task (2020)
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• [Journal Article] Earwig fan designing : biomimetic and evolutionary biology applications (2020)
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• [Journal Article] Editorial : The Earliest-Born Cortical Neurons as Multi-Tasking Pioneers : Expanding Roles for Subplate Neurons in Cerebral Cortex Organization and Function (2020)
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  • Author(s): Atsuko Gonda, Koji Takada, Ryo C. Yanagita, Shingo Dan, and Kazuhiro Irie*
  • Journal Title: Bioscience, Biotechnology and Biochemistry Volume: 85 Issue: 1 Pages: 168-180
  • DOI: 10.1093/bbb/zbaa024
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• [Journal Article] Efficient engraftment of genetically modified cells is necessary to ameliorate 1 central nervous system involvement of murine model of mucopolysaccharidosis type II by hematopoietic stem cell targeted gene therapy. (2020)
  • Author(s): Saori Miwa, Ayako M. Watabe, Yohta Shimada, Takashi Higuchi, Hiroshi Kobayashi, Takahiro Fukuda, Fusao Kato, Hiroyuki Ida, Toya Ohashi
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• [Journal Article] FLCN alteration drives metabolic reprogramming towards nucleotide synthesis and cyst formation in salivary gland (2020)
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• [Journal Article] Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer. (2020)
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  • Journal Title: Cell Rep. Volume: 31 Issue: 5 Pages: 107610
  • DOI: 10.1016/j.celrep.2020.107610
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  • Author(s): Hata, M., Kinoshita, H., Hayakawa, Y., (他12名), Kon, S., Tomita, H., Wang, T. C., Koike, K.
  • Journal Title: Gastroenterology Volume: 158 Pages: 1650-1666
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  • Author(s): Masai H, Tanaka T.
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• [Journal Article] Hereditary pancreatitis model by blastocyst complementation in mouse. (2020)
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• [Journal Article] High Sensitivity In Vivo Imaging of Cancer Metastasis Using a Near-Infrared Luciferin Analogue seMpai (2020)
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  • Author(s): Kanako Maehata, Kimiko Shimizu*, Tomoko Ikeno, Qiuyi Wang, Ayaka Sakurai, Zefeng Wei, Yue Pan, Toshifumi Takao and Yoshitaka Fukada
  • Journal Title: iScience Volume: 23 Issue: 10 Pages: 101559
  • DOI: 10.1016/j.isci.2020.101559
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  • Author(s): Htun, Y. Nakamura, S. Kusaka, T
  • Journal Title: Pediatric Research
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• [Journal Article] Imaging of activity-dependent local translation in dendrite using photoconvertible protein. (2020)
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• [Journal Article] Impact of tissue macrophage proliferation on peripheral and systemic insul in resistance in obese mice with diabetes (2020)
  • Author(s): Morita Y, Senokuchi T, Yamada S, Wada T, Furusho T, Matsumura T, Ishii N, Murakami-Nishida S, Nisida S, Motoshima H, Komohara Y, Yamagata K, Araki E
  • Journal Title: BMJ Open Diabetes Research & Care Volume: 8 Pages: e001578
  • DOI: 10.1136/bmjdrc-2020-001578
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• [Journal Article] Impairment of spatial memory accuracy improved by Cbr1 copy number resumption and GABA B receptor-dependent enhancement of synaptic inhibition in Down syndrome model mice (2020)
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• [Journal Article] Implications of RNG140 (caprin2)-mediated translational regulation in eye lens differentiation (2020)
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• [Journal Article] Intravenous Edaravone plus Therapeutic Hypothermia Offers Limited Neuroprotection in the Hypoxic- Ischaemic Newborn Piglet (2020)
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  • Journal Title: Neonatology Pages: 1-8
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• [Journal Article] Intraventricular IL-17A administration activates microglia and alters their localization in the mouse embryo cerebral cortex. (2020)
  • Author(s): Tetsuya Sasaki, Saki Tome, Yosuke Takei
  • Journal Title: Molecular Brain Volume: 13 Issue: 1 Pages: 93
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• [Journal Article] Kruppel-Like Factor 4 upregulates Matrix Metalloproteinase 13 expression in chondrocytes via mRNA stabilization. (2020)
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• [Journal Article] LDL-mimetic lipid nanoparticles prepared by surface KAT ligation for in vivo MRI of atherosclerosis (2020)
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  • Journal Title: Chem Sci Volume: 44 Pages: 11998-12008
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  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Linear Consecutive Hexaoxazoles as G4 Ligands Inducing Chair-type Anti-parallel Topology of Telomeric G-Quadruplex (2020)
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• [Journal Article] Linear ubiquitin code : Its writer, erasers, decoders, inhibitors, and implications in disorders. (2020)
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• [Journal Article] Localization Mechanism of Myosin Id, an ASD Risk Gene Product in Dendritic Spines (2020)
  • Author(s): Sasaki T, Takei Y.
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• [Journal Article] Lung fibroblasts produce IL-33 in response to stimulation with retinoblastoma-binding protein 9 via production of prostaglandin E2 (2020)
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  • Journal Title: International Immunology Volume: 32 Issue: 10 Pages: 637-652
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• [Journal Article] Maternal dietary imbalance between omega-6 and omega-3 fatty acids triggers the offspring's overeating in mice (2020)
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• [Journal Article] Meiosis-specific C19orf57/4930432K21Rik/BRME1 modulates localization of RAD51 and DMC1 to DSBs in mouse meiotic recombination (2020)
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  • DOI: 10.1016/j.celrep.2020.107686
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• [Journal Article] Meiotic cohesins mediate initial loading of HORMAD1 to the chromosomes and coordinate SC formation during meiotic prophase (2020)
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  • DOI: 10.1371/journal.pgen.1009048
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• [Journal Article] Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses (2020)
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• [Journal Article] Multiple Roles of Vestigial-Like Family Members in Tumor Development. (2020)
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• [Journal Article] Noradrenaline enhances the excitatory effects of dopamine on medial prefrontal cortex pyramidal neurons in rats. (2020)
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• [Journal Article] Palmitoylated CKAP4 regulates mitochondrial functions through an interaction with VDAC2 at ER&[minus]mitochondria contact sites. (2020)
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• [Journal Article] Pathogenic roles of retinal glia in glaucoma (2020)
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• [Journal Article] Peripheral tetrahydrobiopterin is involved in the pathogenesis of mechanical hypersensitivity in a rodent postsurgical pain model. (2020)
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• [Journal Article] Pharmacologically targetable vulnerability in prostate cancer carrying RB1-SUCLA2 deletion. (2020)
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• [Journal Article] Phosphorylation of the Anaphase Promoting Complex activator FZR1/CDH1 is required for Meiosis II entry in mouse male germ cell. (2020)
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• [Journal Article] Piwi suppresses transcription of Brahma-dependent transposons via Maelstrom in ovarian somatic cells (2020)
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• [Journal Article] Polygenic Risk Scores for Late Smoking Initiation Associated with the Risk of Schizophrenia (2020)
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• [Journal Article] Protocol for disome profiling to survey ribosome collision in humans and zebrafish. (2020)
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  • Journal Title: Genes Volume: 11 Pages: 734
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• [Journal Article] Ribosomal protein S7 ubiquitination during ER stress in yeast is associated with selective mRNA translation and stress outcome (2020)
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• [Journal Article] Ring box protein-1 is associated with a poor prognosis and tumor progression in esophageal cancer. (2020)
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  • DOI: 10.3892/ol.2020.11840
  • Peer Reviewed / Open Access
• [Journal Article] Role of 5-HT1A receptor-mediated serotonergic transmission in the medial prefrontal cortex in acute restraint stress-induced augmentation of rewarding memory of cocaine in mice (2020)
  • Author(s): Chu J, Deyama S, Li X, Motono M, Otoda A, Saito A, Esaki H, Nishitani N, Kaneda K
  • Journal Title: Neuroscience Letters Volume: 743 Pages: 135555
  • DOI: 10.1016/j.neulet.2020.135555
  • Peer Reviewed
• [Journal Article] Role of Clostridium perfringens enterotoxin on YAP activation in colonic sessile serrated adenoma/polyp with dysplasia (2020)
  • Author(s): Fujiwara-Tani R, Fujii K, Mori S, Kishi S, Sasaki T, Ohmori H, Nakashima C, Kawahara I, NishiguchiY, Mori T, Sho M, Kondoh M, Luo Y, Kuniyasu H
  • Journal Title: Int J Mol Sci Volume: 21 Issue: 11 Pages: E3840
  • DOI: 10.3390/ijms21113840
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Role of nuclear claudin-4 in renal cell carcinoma. (2020)
  • Author(s): Owari T, Takamitsu Sasaki T, Fujii K, Fujiwara-Tani R, Kishi S, Mori S, Mori T, Goto K, Kawahara I, .....Luo Y, Tanaka N, Kondoh M, Fujimoto K, Kuniyasu H
  • Journal Title: Int J Mol Sci Volume: 21 Pages: 8340
  • DOI: 10.3390/ijms21218340
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Roles of type-IIa receptor protein tyrosine phosphatases as synaptic organizers (2020)
  • Author(s): Fukai S, Yoshida T.
  • Journal Title: FEBS Journal
  • DOI: 10.1111/febs.15666
  • Peer Reviewed / Open Access
• [Journal Article] Seasonal changes in NRF2 antioxidant pathway regulates winter depression-like behavior (2020)
  • Author(s): T Nakayama, K Okimura, J Shen, YJ Guh, 中略, K Nakayama, N Shiina, N Yamamoto, AS Loudon, T Nishiwaki-Ohkawa, A Shinomiya, T Nabeshima, Y Nakane and T Yoshimura
  • Journal Title: Proc. Natl. Acad. Sci. U.S.A. Volume: 117 Pages: 9594-9603
  • DOI: 10.1073/pnas.2000278117
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Serotonergic control in initiating defensive responses to unexpected tactile stimuli in the trap-jaw ant Odontomachus kuroiwae (2020)
  • Author(s): Aonuma H.
  • Journal Title: Journal of Experimental Biology Volume: 223 Issue: 19 Pages: jeb228874
  • DOI: 10.1242/jeb.228874
  • Peer Reviewed
• [Journal Article] Sexually dimorphic role of oxytocin in medaka mate choice (2020)
  • Author(s): Yokoi S, Naruse K, Kamei Y, Ansai S, Kinoshita M, Mito M, Iwasaki S., Inoue S, Okuyama T, Nakagawa S, Young LJ, and Takeuchi H.
  • Journal Title: Proc Natl Acad Sci USA. Volume: 117 Issue: 9 Pages: 4802-4808
  • DOI: 10.1073/pnas.1921446117
  • Peer Reviewed
• [Journal Article] SGLT2 inhibition mediates protection from diabetic kidney disease by promoting ketone body-induced mTORC1 inhibition. (2020)
  • Author(s): Tomita I, Kume S, Sugahara S, ..., Ogita H, Araki SI, Maegawa H.
  • Journal Title: Cell Metab. Volume: 32 Pages: 404-419
  • DOI: 10.1016/j.cmet.2020.06.020
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Siwi levels reversibly regulate secondary piRISC biogenesis by affecting Ago3 body morphology in Bombyxmori (2020)
  • Author(s): Nishida KM, Sakakibara K, Sumiyoshi T, Yamazaki H, Mannen T, Kawamura T, Kodama T, Siomi MC.
  • Journal Title: EMBO J. Volume: 39 Pages: e105130
  • DOI: 10.15252/embj.2020105130
  • Peer Reviewed / Open Access
• [Journal Article] Specific Neuroligin3-αNeurexinl signaling regulates GABAergic synaptic function in mouse hippocampus. (2020)
  • Author(s): Uchigashima M, Konno K, Demchak E, Cheung A, Watanabe T, Keener D G, Abe M, Sakimura K, Sasaoka T, Uemura T, Imamura Karasawa Y, Watanabe M, Futai K.
  • Journal Title: Elife Volume: 9 Pages: e59545
  • DOI: 10.7554/eLife.59545
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Staurosporine and venetoclax induce the caspase-dependent proteolysis of MEF2D-fusion proteins and apoptosis in MEF2D-fusion (+) ALL cells. (2020)
  • Author(s): Tange N, Hayakawa F, Yasuda T, Odaira K, Yamamoto H, Hirano D, Sakai T, Terakura S, Tsuzuki S, Kiyoi H.
  • Journal Title: Biomed Pharmacother. Volume: 128 Pages: 110330-110340
  • DOI: 10.1016/j.biopha.2020.110330
  • Peer Reviewed / Open Access
• [Journal Article] Steroid metabolites for diagnosing and predicting clinicopathological features in cortisol-producing adrenocortical carcinoma. (2020)
  • Author(s): Suzuki S, Minamidate T, Shiga A, Ruike Y, Ishiwata K, Naito K, Ishida A, Deguchi H, Fujimoto M, Koide H, Tatsuno I, Ikeda JI, Yamazaki Y, Sasano H, Yokote K.
  • Journal Title: BMC Endocr Disord. Volume: 20
  • DOI: 10.1186/s12902-020-00652-y
  • Peer Reviewed / Open Access
• [Journal Article] Stress-responsive MTK1 SAPKKK serves as a redox sensor that mediates delayed and sustained activation of SAPKs by oxidative stress (2020)
  • Author(s): Moe Matsushita, Takanori Nakamura, Hisashi Moriizumi, Hiroaki Miki, Mutsuhiro Takekawa
  • Journal Title: Science Advances Volume: 6 Issue: 26 Pages: eaay9778
  • DOI: 10.1126/sciadv.aay9778
  • Peer Reviewed / Open Access
• [Journal Article] Suppression of DNA Double-Strand Break Formation by DNA Polymerase β in Active DNA Demethylation Is Required for Development of Hippocampal Pyramidal Neurons (2020)
  • Author(s): Akiko Uyeda, Kohei Onishi, Teruyoshi Hirayama, Satoko Hattori, Tsuyoshi Miyakawa, Takeshi Yagi, Nobuhiko Yamamoto, and Noriyuki Sugo
  • Journal Title: The Journal of Neuroscience Volume: 40 Issue: 47 Pages: 9012-9027
  • DOI: 10.1523/JNEUROSCI.0319-20.2020
  • Peer Reviewed
• [Journal Article] Sustaining temporal attention prevents habit expression during operant learning in rats (2020)
  • Author(s): Lin, Z, Nishikawa, H, Iguchi, Y, Iwanami, A, Kikuchi, M, Toda, S
  • Journal Title: Scientific Reports Volume: 10 Issue: 1 Pages: 10303
  • DOI: 10.1038/s41598-020-67304-y
  • Peer Reviewed / Open Access
• [Journal Article] Synthesis and biological activities of simplified aplysiatoxin analogs focused on the CH/pi interaction. (2020)
  • Author(s): Takumi Kobayashi, Ryo, C. Yanagita, Kazuhiro Irie
  • Journal Title: Bioorganic & Medicinal Chemistry Letters Volume: 30 Pages: 127657
  • DOI: 10.1016/j.bmcl.2020.127657
  • Peer Reviewed
• [Journal Article] Target identification of a macrocyclic hexaoxazole G-quadruplex ligand using post-target-binding visualization. (2020)
  • Author(s): Yasuda M, Ma Y, Okabe S, Wakabayashi Y, Su D, Chang YT, Seimiya H, Tera M, Nagasawa K.
  • Journal Title: Chem Commun Volume: 56 Pages: 12905-12908
  • DOI: 10.1039/d0cc04957c
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] The antimalarial compound atovaquone inhibits Zika and dengue virus infection by blocking E protein-mediated membrane fusion. (2020)
  • Author(s): Yamamoto, M., Ichinohe, T., Watanabe, A., Kobayashi, A., Zhang, R., Song, J., Kawaguchi, Y., Matsuda, Z. and Inoue, J.
  • Journal Title: Viruses Volume: 12 Pages: 1475
  • DOI: 10.3390/v1212475
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The Autism-Related Protein SETD5 Controls Neural Cell Proliferation through Epigenetic Regulation of rDNA Expression (2020)
  • Author(s): Tadashi Nakagawa, Satoko Hattori, Tsuyoshi Miyakawa, Keiko Nakayama
  • Journal Title: iScience Volume: 23 Issue: 4 Pages: 101030
  • DOI: 10.1016/j.isci.2020.101030
  • Peer Reviewed / Open Access
• [Journal Article] The Mi-2 nucleosome remodeler and the Rpd3 histone deacetylase are involved in piRNA-guided heterochromatin formation (2020)
  • Author(s): Mugat B, Nicot S, Chavez CV, Jourdan C, Sato K, Basyuk E, Juge F, Siomi MC, Pelisson A, Chambeyron S.
  • Journal Title: Nature Com. Volume: 11 Pages: 2828
  • DOI: 10.1038/s41467-020-16635-5
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The novel ciliogenesis regulator DYRK2 governs Hedgehog signaling during mouse embryogenesis (2020)
  • Author(s): Yoshida S, Aoki K, Fujiwara K, Nakakura T, Kawamura A, Yamada K, Ono M, Yogosawa S, Yoshida K.
  • Journal Title: eLife Volume: 9 Pages: e57381
  • DOI: 10.7554/eLife.57381
  • Peer Reviewed / Open Access
• [Journal Article] The pentatricopeptide repeat protein PGR3 is required for the translation of petL and ndhG by binding their 5'UTRs. (2020)
  • Author(s): Higashi H, Kato Y, Fujita T, Iwasaki S, Nakamura M, Nishimura Y, Takenaka M, and Shikanai T.
  • Journal Title: Plant Cell Physiol.
  • DOI: 10.1093/pcp/pcaa180
  • Peer Reviewed
• [Journal Article] The role of calcium metabolism in keratinocyte differentiation (2020)
  • Author(s): Okumura K, Wakabayashi Y
  • Journal Title: Trends in Cancer Research Volume: 14 Pages: 45-47
  • Peer Reviewed / Open Access
• [Journal Article] The synchronized gene expression of retrotransposons and type I interferon in dermatomyositis (2020)
  • Author(s): Kuriyama Y, Shimizu A, Kanai S, Oikawa D, Tokunaga F, Tsukagoshi H, Ishikawa O.
  • Journal Title: J Am Acad Dermatol.
  • DOI: 10.1016/j.jaad.2020.05.051
  • Peer Reviewed
• [Journal Article] Tight Junction Structure and Function Revisited (2020)
  • Author(s): Tetsuhisa Otani, Mikio Furuse
  • Journal Title: Trends in Cell Biology Volume: 30 Issue: 10 Pages: 805-817
  • DOI: 10.1016/j.tcb.2020.08.004
  • Peer Reviewed
• [Journal Article] Time-restricted G-protein signaling pathways via GPR176. Gz, and RGS16 set the pace of the master circadian clock in the suprachiasmatic nucleus. (2020)
  • Author(s): Nakagawa S, Nguyen Pham KT, Shao X, and Doi M
  • Journal Title: Int J Mol Sci Volume: 21 Pages: 5055
  • DOI: 10.3390/ijms21145055
  • Peer Reviewed / Open Access
• [Journal Article] Translational landscape of protein-coding and non-protein-coding RNAs upon light exposure in Arabidopsis (2020)
  • Author(s): Kurihara Y., Makita Y., Shimohira H., Fujita T., Iwasaki S., and Matsui M.
  • Journal Title: Plant Cell Physiol. Volume: 61 Issue: 3 Pages: 536-545
  • DOI: 10.1093/pcp/pcz219
  • Peer Reviewed
• [Journal Article] Vestigial-like family member 3 (VGLL3), a cofactor for TEAD transcription factors, promotes cancer cell proliferation by activating the Hippo pathway (2020)
  • Author(s): Naoto Hori, Kazuyuki Okada, Yuki Takakura, Hiroyuki Takano, Naoto Yamaguchi, Noritaka Yamaguchi
  • Journal Title: Journal of Biological Chemistry Volume: 295 Pages: 8798-8807
  • DOI: 10.1074/jbc.RA120.012781
  • Peer Reviewed
• [Journal Article] Visually cued fear conditioning test for memory impairment related to cortical function (2020)
  • Author(s): Kuboyama K, Shirakawa Y, Kawada K, Fujii N, Ojima D, Kishimoto Y, Yamamoto T, Yamada MK
  • Journal Title: Neuropsychopharmacol. Rep. Volume: 40 Pages: 371-375
  • DOI: 10.1002/npr2.12146
  • Peer Reviewed
• [Journal Article] がん性サルコペニアに対する栄養介入 (2020)
  • Author(s): 森 拓也, 川原 勲, 額賀翔太, 宮川良博, 後藤 桂, 大森 斉, 國安弘基
  • Journal Title: 奈良医学雑誌 Volume: 71 Issue: 1-3 Pages: 1-5
  • Peer Reviewed
• [Journal Article] ラットを用いたオプトジェネティクス(光遺伝学) (2020)
  • Author(s): 八尾寛, 深沢有吾, 冨田浩史, 五十嵐敬幸
  • Journal Title: LABI021 Volume: 80 Pages: 5-8
  • Int'l Joint Research
• [Journal Article] 時計遺伝子の転写のシス制御エレメントに点変異を入れると体内時計はどうなるのか (2020)
  • Author(s): Nguyen Pham Khanh Tien、土居雅夫
  • Journal Title: Journal of Japanese Biochemical Society Volume: 92 Issue: 5 Pages: 735-739
  • DOI: 10.14952/SEIKAGAKU.2020.920735
  • Peer Reviewed / Open Access
• [Presentation] 生殖細胞における体細胞分裂から減数分裂への切り替え機構と性差 (2021)
  • Author(s): 石黒啓一郎
  • Organizer: 第126回日本解剖学会総会
  • Invited
• [Presentation] AMPA受容体のパルミトイル化修飾異常に伴うてんかん発作 (2021)
  • Author(s): 林 崇
  • Organizer: 2020年度生理学研究所研究会
  • Invited
• [Presentation] Aplysiatoxin/oscillatoxin類の網羅的合成研究 (2021)
  • Author(s): 西川俊夫
  • Organizer: 反応集積化が導く中分子戦略 : 高次生物機能分子の創製 令和2年度取りまとめシンポジウム
• [Presentation] Association of a neutral contextual memory with a fearful experience induces synapse formation selectively in Arc-expressing neurons of the mouse retrosplenial cortex (2021)
  • Author(s): Minatohara K, Ohnami S, Okabe S, Bito H, Okuno H.
  • Organizer: SfN Global Connectome (北米神経科学学会オンライン研究発表)
  • Int'l Joint Research
• [Presentation] Carbonic anhydrase related protein Car8 is essential for the establishment of cerebellar neuronal circuit, regulating precise matching of pre and postsynapse in Purkinje cell (2021)
  • Author(s): Taisuke Miyazaki, Miwako Yamasaki, Kenji Sakimura, Masahiko Watanabe
  • Organizer: 第126回日本解剖学会総会・全国学術集会
• [Presentation] Crosstalk of tumor cells and tumor endothelial cells by forming cell clusters promotes tumor metastasis (2021)
  • Author(s): 間石 奈湖, 梅山 悠伊, 菊地 央, 古御堂 純, 佐藤 峰嘉, 武田 遼, Dorcas A. Annan, 篠原 信雄, 樋田 泰浩, 樋田 京子
  • Organizer: CVMW2020/第28回日本血管生物医学会学術集会
• [Presentation] Glutaminolysisの糖尿病および癌における役割解明 (2021)
  • Author(s): 鈴木佐和子、田中知明、横手幸太郎
  • Organizer: 第58回糖尿病関東甲信越地方会 若手研究者シンポジウム
  • Invited
• [Presentation] IL-17a affects activity and localization of microglia in the embryo cerebral cortex. (2021)
  • Author(s): Tetsuya Sasaki, Yosuke Takei.
  • Organizer: SfN Global Connectome
  • Int'l Joint Research
• [Presentation] Intraventricular Interleukin-17A administration activates microglia and altered their localization in the cerebral cortex of fetal brain. (2021)
  • Author(s): Tetsuya Sasaki, Yosuke Takei.
  • Organizer: International College of Neuropsychopharmacology 2021 Virtual World Congress.
  • Int'l Joint Research
• [Presentation] MEIOSIN directs the switch from mitosis to meiosis (2021)
  • Author(s): Kei-ichiro ISHIGURO
  • Organizer: The 4th KAIST-KU Workshop and Joint Symposium "Facilitating Collaboration in Biomedical Engineering Research"
  • Int'l Joint Research / Invited
• [Presentation] MSM由来ES細胞を用いた発がん抵抗性遺伝子座の解析 (2021)
  • Author(s): 若林雄一
  • Organizer: 2020年度先端モデル動物支援プラットフォーム成果発表会
  • Invited
• [Presentation] Phosphorylation of GAP-43 T172 is a molecular marker of growing axons in a wide range of mammals including primates (2021)
  • Author(s): Masayasu Okada
  • Organizer: 第9回生理研-霊長研-新潟脳研合同シンポジウム
• [Presentation] Rho A rescues senescence heart by maintaining mitochondrial function via Parkin. (2021)
  • Author(s): Joanne Ern Chi Soh、清水昭男、Md Rasel Molla、米野雅大、扇田久和
  • Organizer: 日本循環器学会
• [Presentation] UFMylation経路異常による薬剤感受性の変化に関する検討 (2021)
  • Author(s): 齋藤彩夏、寺井秀樹、浜本純子、岡田正彦、福島貴大、篠崎太郎、堀内康平、杉原快、光石彬史、胡谷俊樹、竹原朋宏、池村辰之介、安田浩之、川田一郎、副島研造、福永興壱
  • Organizer: 第61回日本呼吸器学会学術講演会
• [Presentation] オキサゾール骨格を有するグアニン四重鎖特異的turn-on型リガンドの開発 (2021)
  • Author(s): 綿谷 成恭、若林 勇樹、寺 正行、馬 悦、長澤 和夫
  • Organizer: 日本化学会 第101回春季年会
• [Presentation] プロテインデグロンシステムによるがん免疫療法を用いたがん細胞増殖の抑制 (2021)
  • Author(s): 成瀬智恵、杉原一司、杉山文博、浅野雅秀
  • Organizer: 第68回日本実験動物学会
• [Presentation] ミトコンドリアオートファジーの誘導機構 (2021)
  • Author(s): 神吉智丈
  • Organizer: J-mit 特別 オンラインシンポジウム
  • Invited
• [Presentation] ヨウ化アリールとアルキニルホウ素化合物のカップリング反応を利用した[2]ロタキサンの合成とその動的挙動 (2021)
  • Author(s): 永山 晶、海老沢 優弥、武藤 雄一郎、吉越 裕介、斎藤 慎一
  • Organizer: 日本化学会第101春季年会
• [Presentation] ラットモデルから紐解くKeap1-Nrf2システムの新たな役割 (2021)
  • Author(s): 田口恵子
  • Organizer: 先端モデル動物支援プラットフォーム成果発表会
  • Invited
• [Presentation] リガンド相互作用が及ぼすグアニン四重鎖のS1ヌクレアーゼ活性への影響 (2021)
  • Author(s): 石川 遼、安田 瑞穂、馬 悦、長澤 和夫、寺 正行
  • Organizer: 日本化学会 第101回春季年会
• [Presentation] ルテニウム触媒による2-アルキニルフェニルボロン酸の1,2-炭素転位を伴う環化異性化反応 (2021)
  • Author(s): 近田 史仁、渡辺 拓真、武藤 雄一郎、吉越 裕介、斎藤 慎一
  • Organizer: 日本化学会第101春季年会
• [Presentation] 神経幹細胞特異的イノシン三リン酸分解酵素ノックアウトマウスは脳神経細胞脱分極とてんかん発作を示す (2021)
  • Author(s): 土本大介
  • Organizer: 2020年度先端モデル動物支援プラットフォーム成果発表会
  • Invited
• [Presentation] 生殖細胞特異的ZFP541複合体は減数分裂前期脱出の転写制御に働く (2021)
  • Author(s): 高田幸, 小寺千聡, 竹本一政, 坂下陽彦, 前田亮, 島田龍輝, 立花 誠, 行川 賢, 荒木喜美, 石黒啓一郎
  • Organizer: 14回 日本エピジェネティクス研究会年会
• [Presentation] 線虫RIG-IホモログDRH-1の調製と核酸依存性ATPase活性評価 (2021)
  • Author(s): 浴 俊彦、小林大士、村上匠蔵、広瀬 侑
  • Organizer: 日本薬学会第141年会
• [Presentation] 胎児期メス生殖細胞における減数分裂開始と細胞周期G1/S期の同調のメカニズム (2021)
  • Author(s): 石黒 啓一郎
  • Organizer: 第38回染色体ワークショップ第19回核ダイナミクス研究会
• [Presentation] 胎児期低栄養で発現が増加するSLC22a23輸送体の機能解析 (2021)
  • Author(s): 内村康寛、日野広大、木村智子、篠原正和、醍醐弥太郎、宇田川潤
  • Organizer: 第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会 合同大会
• [Presentation] 方位弁別学習後のラット一次視覚野に見られる低コントラスト優位な神経活動 (2021)
  • Author(s): 木村梨絵
  • Organizer: 第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会 合同大会
  • Invited
• [Presentation] Vmat1ヒト型改変マウスを用いた網羅的行動解析 (2020)
  • Author(s): *佐藤大気・井上-上野由紀子・森本由起・井上高良・服部聡子・Giovanni Sala・宮川剛・河田雅圭
  • Organizer: 日本進化学会第22回オンライン大会
• [Presentation] 腫瘍優先的にP53応答を引き出す小児白血病の新たな分子標的治療戦略 (2020)
  • Author(s): 河原 康一、古川 龍彦
  • Organizer: 第58回日本癌治療学会学術集会
• [Presentation] [2]ロタキサンにおける回転運動の制御 (2020)
  • Author(s): 川嵜 祐介、小金澤 寛、武藤 雄一郎、吉越 裕介、斎藤 慎一
  • Organizer: 日本化学会第101春季年会
• [Presentation] 5-Aminolevulinic acid overcomes hypoxia-induced resistance to radiation therapy thorough increase of mitochondrial reactive oxygen species in prostate cancer (2020)
  • Author(s): Owari T, Kishi S, Mori S, Miyake M, Nakai Y, Tanaka N, Fujimoto K, Kuniyasu H
  • Organizer: 79th Annual Meeting of Japanese Association for Cancer, Hiroshima, 2020.10.1-3
• [Presentation] A central psychosomatic neural pathway that drives sympathetic and behavioral stress responses (2020)
  • Author(s): Nakamura, K.
  • Organizer: virtual 8th International Conference on the Physiology and Pharmacology of Temperature Regulation (vPPTR) 2020
  • Int'l Joint Research / Invited
• [Presentation] A novel mutation in transmembrane protein 168 causes fatal ventricular arrhythmogenesis in Brugada syndrome. (2020)
  • Author(s): Md Rasel Molla、清水昭男、扇田久和
  • Organizer: European Society of Cardiology
  • Int'l Joint Research
• [Presentation] A novel p53 downstream tumor promotion pathway, p53-IER5- HSF1 pathway, that contributes to stress resistance and tumor progression. (2020)
  • Author(s): Rieko Ohki
  • Organizer: 第43回日本分子生物学会年会
  • Invited
• [Presentation] ABCA1欠損は緑内障発症過程早期でのグリオーシスを誘導する (2020)
  • Author(s): 篠崎陽一、行方和彦、柏木賢治、大野伸彦、繁冨英治、原田高幸、小泉修一
  • Organizer: 第63回日本神経化学会大会
• [Presentation] Activity- and septin-dependent extension of smooth ER into dendritic spines as a synaptic basis of memory consolidation (2020)
  • Author(s): Kinoshita M, Ageta-Ishihara N, Fukazawa Y, Kengaku M, Takao K, Inokuchi K, Miyakawa T, Bito H.
  • Organizer: 第43回日本神経科学大会
• [Presentation] Akt dysregulation by loss of PHLDA3 is an important determinant of pancreatic neuroendocrine tumor progression. (2020)
  • Author(s): Yu Chen, Sadahiro Iwabuchi, Tohru Kiyono, Shigeyuki Magi, Yasuhito Arai, Akihiko Yokoyama, Mariko Okada, Shinichi Hashimoto, Kentaro Semba, Rieko Ohki.
  • Organizer: 第79回日本癌学会学術総会
• [Presentation] Alteration of ρ0 cells in in vivo environment (2020)
  • Author(s): Mori S, Fujiwara-Tani R, Kishi S, Kuniyasu H
  • Organizer: 79th Annual Meeting of Japanese Association for Cancer
• [Presentation] Anti-proliferative effect of lenvatinib in combination with IRAK1/4 inhibitor I in anaplastic thyroid carcinoma cells (2020)
  • Author(s): 川村佳史、西條憲、今井源、石岡千加史
  • Organizer: 日本癌学会
  • Int'l Joint Research
• [Presentation] Antitumor effect of gluconeogenesis induced by NFYA (2020)
  • Author(s): Goki Tsujimoto, Chiaki Takahashi, Nobuhiro Okada
  • Organizer: 第79回日本癌学会学術総会
• [Presentation] Area-specific laminar organization is regulated by thalamocortical axons through axon-derived secretory protein VGF in developing neocortex (2020)
  • Author(s): Haruka Sato, Jun Hatakeyama, Takuji Iwasato, Nobuhiko Yamamoto, Kenji Shimamura
  • Organizer: 第53回日本発生生物学会
• [Presentation] Atypical linear ubiquitination-mediated regulation of inflammatory responses and proteinopathies (2020)
  • Author(s): 徳永文稔、伊東秀文、及川大輔
  • Organizer: 第43回日本分子生物学会年会
  • Invited
• [Presentation] A環およびF環を改変したラメラリンN誘導体の合成研究 (2020)
  • Author(s): 大田原有香, 小田亮平, 福田勉, 小野寺玄, 木村正成
  • Organizer: 2020年日本化学会九州支部秋期研究発表会
• [Presentation] Characterizing and engineering microbial rhodopsins for genetically encoded voltage indicator (2020)
  • Author(s): Masayuki Sakamoto, Xiao Min Zhang, Rika Kurihara, Keiichi Kojima, Yuki Sudo, Haruhiko Bito
  • Organizer: 第43回日本神経科学大会
  • Int'l Joint Research
• [Presentation] Circadian PER2 protein oscillations do not persist when de novo translation is inhibited in cultured mouse embryonic fibroblasts (2020)
  • Author(s): Xinyan Shao, Takahito Miyake, and Masao Doi
  • Organizer: 第43回日本分子生物学会年会
• [Presentation] Claspin, a key regulator of replication checkpoint, is differentially regulated in cancer and non-cancer cells. (2020)
  • Author(s): Chi-Chun Yang and Hisao Masai
  • Organizer: 11th international symposium on DNA Damage Response & Human Disease (isDDRHD-2020)
  • Int'l Joint Research / Invited
• [Presentation] Clostridium perfringens enterotoxin activates YAP in oral squamous cell carcinomas (2020)
  • Author(s): Nakashima C, Yamamoto K, Kishi S, Sasaki T, Ohmori H, Fujiwara-Tani R, Mori S, Fujii K, Nishiguchi Y, Kondoh M, Tadaaki K, Kuniyasu H
  • Organizer: 79th Annual Meeting of Japanese Association for Cancer, Hiroshima, 2020.10.1-3
• [Presentation] Cortical abnormality due to interleukin 17A and its involvement in pathophysiology of ASD (2020)
  • Author(s): Tetsuya Sasaki, Peiyi Bao, Yosuke Takei.
  • Organizer: NPBPPP2020.
• [Presentation] Cortical dysplasia caused by interleukin 17A and its involvement in pathophysiology of ASD. (2020)
  • Author(s): Tetsuya Sasaki, Saki Tome, Yosuke Takei.
  • Organizer: The 43rd Annual Meeting of the Japan Neuroscience Society.
• [Presentation] CRH/GRH/TRH/LHRH四者負荷試験の代替としてのGHRP2/TRH/LHRH三者負荷試験の有用性 (2020)
  • Author(s): 鈴木佐和子、類家裕太郎、石渡一樹、内藤久美子、出口ハンナ、石田晶子、志賀明菜、田村愛、藤本真徳、小出尚史、横手幸太郎.
  • Organizer: 第93回日本内分泌学会学術総会
• [Presentation] D2受容体欠損マウスの3レバーオペラント課題の順序学習の障害 (2020)
  • Author(s): 米田 貢, 谷上 颯, 中川 雅嵩, 越後 亮介, 西川 杏子, 笹岡 俊邦, 少作 隆子
  • Organizer: 第43回日本神経科学大会
• [Presentation] D2受容体発現細胞における NMDA受容体のマグネシウムブロックの減少により引き起こされる運動制御と学習および記憶の変化の分析 (2020)
  • Author(s): 笹岡 俊邦、齊藤 奈英、知見 聡美、阿部 学、川村 名子、鍋島 曜子、鍋島 陽一、田井中 一貴、崎村 建司、南部 篤
  • Organizer: 第63回日本神経化学会大会
• [Presentation] Development of artificial tumorigenesis model from iPSC-based neural crest cells (2020)
  • Author(s): Kyosuke Mukae, Hisanori Takenobu, Hiroaki Kanda, Miki Ohira, Yuki Endo, Masayuki Haruta, Junya Toguchida, Kenji Osafune, Tatsutoshi Nakahata, Takehiko Kamijo
  • Organizer: 第62回日本小児血液・がん学会学術集会
• [Presentation] Dipeptidyl Peptidase III Prevents Cardiac Dysfunction and Nephropathy in Type II Diabetes. (2020)
  • Author(s): 米野雅大、清水昭男、扇田久和
  • Organizer: 日本循環器学会
• [Presentation] Dual targeting of DDX3 and eIF4A by the translation inhibitor Rocaglamide A (2020)
  • Author(s): Iwasaki S
  • Organizer: The 93rd Annual Meeting of The Japan Biochemical Society
  • Invited
• [Presentation] Effects of interleukin 17A on cortical architecture and the involvement in ASD pathology. (2020)
  • Author(s): Peiyi Bao, Tetsuya Sasaki, Takuya Takada, Yosuke Takei.
  • Organizer: The 63rd Annual Meeting of the Japanese Society for Neurochemistry.
• [Presentation] Effects of medium-chain fatty acids on cancer-derived myocardial atrophy (2020)
  • Author(s): Nukaga S, Mori T, Luo Y, Kawahara I, Miyagawa Y, Goto K, Fujiwara-Tani R, Kishi S, Mori S, Ohmori H, Kuniyasu H
  • Organizer: 79th Annual Meeting of Japanese Association for Cancer, Hiroshima, 2020.10.1-3
• [Presentation] Establishment and demonstration of a novel spike analysis for neuronal activity during sensorimotor transformation. (2020)
  • Author(s): Kawabata M., Nonomura S, Yoshizawa T, Rios A, Sakairi T, Sakai Y, Isomura Y
  • Organizer: FENS Forum 2020 (Virtual : SEC Centre, Glasgow, UK)
  • Int'l Joint Research
• [Presentation] Expression mapping of GluD1 and GluD2 glutamate receptors in adult mouse brain (2020)
  • Author(s): Kohtarou Konno, Taisuke Miyazaki, Miwako Yamasaki, Kenji Sakimura, and Masahiko Watanabe
  • Organizer: 第43回神経科学学会
• [Presentation] G4/RNA-DNAハイブリッドに依存する環状染色体DNAの複製機構 (2020)
  • Author(s): 正井 久雄、田中 卓、鷺 朋子、深津 理乃、関 由美香
  • Organizer: 第43回日本分子生物学会年会
• [Presentation] GABA合成酵素GAD67ハプロ不全と新生仔期NMDA型グルタミン酸受容体遮断の組み合わせにより生じる行動学的表現型 (2020)
  • Author(s): 藤原和之、佐藤匠、宮坂佳樹、真下知士、柳川右千夫
  • Organizer: NPBPPP2020合同年会
• [Presentation] Genetically encoded voltage indicators and their application. (2020)
  • Author(s): Masayuki Sakamoto
  • Organizer: 遺伝研研究会「哺乳類脳の機能的神経回路の構築メカニズム」
  • Int'l Joint Research / Invited
• [Presentation] HMGB1 regulates mitochondrial transfer from mesenchymal stem cells to cancer cells damaged by 5-fluorouracil (2020)
  • Author(s): Sasaki R, Kishi S, Mori S, Fijiwara-Tani R, Sasaki T, Luo Y, Kuniyasu H
  • Organizer: 79th Annual Meeting of Japanese Association for Cancer
• [Presentation] HNF-1αによる膵α細胞機能制御メカニズムの解明 (2020)
  • Author(s): 佐藤叔史、Md Mostafizur Rahman、羽根田昌樹、水本智也、津山友徳、吉澤達也、北村忠弘、Frank J Gonzalez、山村研一、山縣和也
  • Organizer: 第63回日本糖尿病学会年次学術集会
• [Presentation] Identification of lonidamine-binding proteins and its functions (2020)
  • Author(s): 青山愛、藤元次郎、仙波憲太郎
  • Organizer: 第79回日本癌学会学術総会
• [Presentation] Imaging voltage in neurons with genetically encoded indicators. (2020)
  • Author(s): Masayuki Sakamoto
  • Organizer: 生理研 記憶研究会
  • Int'l Joint Research / Invited
• [Presentation] Impact of fatty acid synthesis regulated by NFYA on malignant progression of breast cancer (2020)
  • Author(s): Chihiro Ueki, Goki Tsujimoto, Susumu Kohno, Chiaki Takahashi, Nobuhiro Okada
  • Organizer: 第43回日本分子生物学会年会
• [Presentation] Interleukin-17A affects the activation status of microglia in the cerebral cortex. (2020)
  • Author(s): Tetsuya Sasaki, Takuya Takada, Yosuke Takei.
  • Organizer: TGSW2020
  • Int'l Joint Research
• [Presentation] Intracerebral expression pattern of ASD risk gene MyosinId mRNA and localization of the translation products to dendrite spines (2020)
  • Author(s): Tetsuya Sasaki, Yosuke Takei.
  • Organizer: The 63rd Annual Meeting of the Japanese Society for Neurochemistry.
• [Presentation] Isoflavone (S)-erypoegin K as a novel topoisomerase II inhibitor (2020)
  • Author(s): N. Kaneda
  • Organizer: 第79回日本癌学会学術総会
• [Presentation] Linoleic acid-related signal pathway associated with dormant stemness (2020)
  • Author(s): Ogata R, Mori S, Fujiwara-Tani R, Kishi S, Kuniyasu H
  • Organizer: 79th Annual Meeting of Japanese Association for Cancer
• [Presentation] IncRNAの翻訳と精神疾患 (2020)
  • Author(s): 松本 有樹修
  • Organizer: NPBPPP2020合同年会(第50回日本神経精神薬理学会年会、第42回日本生物学的精神医学会年会、第4回日本精神薬学会総会・学術集会)
  • Invited
• [Presentation] Localization of Myosin Id, an ASD Risk Gene Product in Dendritic Spines. (2020)
  • Author(s): Peiyi Bao, Tetsuya Sasaki, Yosuke Takei.
  • Organizer: The 43rd Annual Meeting of the Japan Neuroscience Society.
• [Presentation] Long non-coding RNAの翻訳 (2020)
  • Author(s): 松本 有樹修
  • Organizer: 第93回日本生化学会
  • Invited
• [Presentation] Loss of astrocytic ABCA1 induces normal tension glaucoma (2020)
  • Author(s): Shinozaki, Y., Namekata, K., Segawa, T., Ohno, N., Harada, T., Kashiwagi, K., Koizumi, S
  • Organizer: FENS2020
  • Int'l Joint Research
• [Presentation] Lysophosphatidyl acid is involved in radiation brain necrosis through chronic microglial activation (2020)
  • Author(s): Natsuko Kondo, Yoshinori Sakurai, Kuniyuki Kano, Takushi Takata, Kyo Kume, Munetoshi Maeda, Mitsutoshi Setou, Junken Aoki, and Minoru Suzuki
  • Organizer: The 33rd Annual Meeting of the Japanese Society for Radiation Oncology
• [Presentation] Maintenance of Time-dependent Spatial Memory by Neurosteroids in Mice (2020)
  • Author(s): 清水貴美子
  • Organizer: National Institute for Physiological Sciences Conferences Learning & Memory Research Meeting 2020
• [Presentation] Maternal Overnutrition Causes DNA Alkylation in Fetal Liver, Suppresses FasL and Upregulates HIF-1 Signaling Pathway in Neonatal Liver in Non-Alcoholic Steatohepatitis (NASH)/Hepatocellular Carcinoma in Offspring. (2020)
  • Author(s): Takao Takiyama, Ryoichi Besshol, Kazuki Sawamoto, Yumi Takiyama.
  • Organizer: American Diabetes Association 80th Scientific Sessions.
  • Int'l Joint Research
• [Presentation] Mathematical Model of Linear Ubiquitination-mediated NF-κB Activation Pathway (2020)
  • Author(s): Tokunaga F, Oikawa D, Hatanaka N, Suzuki T
  • Organizer: JSPS Core-to-Core Program “Establishing International Research Network of Mathematical Oncology”
  • Int'l Joint Research / Invited
• [Presentation] Mathematical modeling of the recruitment of centriole biogenesis regulators to mother centrioles in the S-phase (2020)
  • Author(s): Takanori Nakamura, Noriko Nishizumi-Tokai, Takashi Nakazawa, Tatsuki Mori, Takashi Suzuki, Mutsuhiro Takekawa
  • Organizer: JSPS Core-to-Core Program "Establishing International Research Network of Mathematical Oncology"
  • Int'l Joint Research / Invited
• [Presentation] MDGA1の欠失による抑制性シナプスの過剰形成は統合失調症様の認知・行動異常をもたらす (2020)
  • Author(s): 山本 融, 尾嶋 大喜, 多田 篤史, 田之上 優, 黒川 直弘, 津島 希海, Md. Razib Hossain, 窪田 剛志, 高橋 弘雄, 岸本 泰司
  • Organizer: 第43回日本神経科学大会
• [Presentation] MEIOSIN directs the switch from mitosis to meiosis in mammalian germ cells (2020)
  • Author(s): Kei-ichiro Ishiguro
  • Organizer: 53rd Annual Meeting of JSDB
  • Int'l Joint Research / Invited
• [Presentation] MEIOSINによる減数分裂のコントロール (2020)
  • Author(s): 石黒啓一郎
  • Organizer: 第65回日本生殖医学会学術講演会・総会 教育講演
  • Invited
• [Presentation] MEIOTIC COHESINS MEDIATE INITIAL CHROMATIN LOADING OF HORMADI AND COORDINATE SC FORMATION DURING MEIOTIC PROPHASE IN MOUSE (2020)
  • Author(s): Yasuhiro Fujiwara, Yuki Horisawa-Takada, Naoki Tani, Hiroki Shibuya, Erina Inoue, Kimi Araki, Yuki Okada, Kei-ichiro Ishiguro
  • Organizer: Cold Spring Harbor Laboratory Meeting 2020 GERM CELLS
  • Int'l Joint Research
• [Presentation] Microexon splicing of Ptprd gene controls locomotor activity and social behavior (2020)
  • Author(s): Ayako Imai, Mizuki Sendo, Hironori Izumi, Keizo Takao, Hisashi Mori, Tomoyuki Yoshida
  • Organizer: 第43回 日本神経科学大会
  • Int'l Joint Research
• [Presentation] miR-142欠損マウスの肝臓における代謝及びミトコンドリア形態変化の機能解析 (2020)
  • Author(s): 森亮一、林洋子、下川功
  • Organizer: 第109回日本病理学会総会
• [Presentation] Mitochondria metabolism is correlated with gemcitabine resistance in MIA-PaCa-2. (2020)
  • Author(s): Fujiwara-Tani R, Sasaki T, Mori S, Kishi S, Kuniyasu H
  • Organizer: 79th Annual Meeting of Japanese Association for Cancer, Hiroshima, 2020.10.1-3
• [Presentation] Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses. (2020)
  • Author(s): Oikawa D, Tokunaga F.
  • Organizer: 第93回日本生化学会大会
  • Invited
• [Presentation] Molecular organization of the macromolecule permeability barrier (2020)
  • Author(s): Tetsuhisa Otani, Thanh Phuong Nguyen, Taichi Sugawara, and Mikio Furuse
  • Organizer: 第72回日本細胞生物学会大会
• [Presentation] NDP52のユビキチン結合性を介した炎症応答・細胞死制御とLUBAC阻害剤の影響 (2020)
  • Author(s): 宮下裕久、及川大輔、寺脇正剛、徳永文稔
  • Organizer: 第93回日本生化学会大会
• [Presentation] Neuronal circuit development of subplate neurons (2020)
  • Author(s): 岡 雄一郎、Murtala Hamza Yahaya、張 永欣 Sheena、佐々木 達也、土井 美幸、谷口 学、猪口 徳一、佐藤 真
  • Organizer: 日本神経科学大会
  • Invited
• [Presentation] Neuronal differentiation is induced by Gli3 in WNT- and SHH- activated medulloblastoma (2020)
  • Author(s): Natsumeda M, Miyahara H, Yoshimura J, Tsukamoto Y, Oishi M, Wataya T, Eberhart CG, Kakita A, Fujii Y
  • Organizer: The 19th International Symposium on Pediatric Neuro-Oncology
  • Int'l Joint Research
• [Presentation] NFYA splicing variant regulates the malignant progression of breast cancer (2020)
  • Author(s): Nobuhiro Okada, Goki Tsujimoto, Kiyotsugu Yoshikawa, Chiaki Takahashi
  • Organizer: 第79回日本癌学会学術総会
  • Int'l Joint Research
• [Presentation] Novel molecular markers for axon growth and regeneration discovered from the growth cone-phosphoproteomes (2020)
  • Author(s): Masayasu Okada, A. Kawasaki, A. Tamada, H. Kitaura, Y. Sato, M. Natsumeda, N. Kimura, N. Kaneko, K. Takeuchi, A. Kakita, Y. Fuji, M. Igarashi
  • Organizer: 第43回日本神経科学学会
  • Int'l Joint Research
• [Presentation] Novel protective effect of vascular smooth muscle RhoA on aortic aneurysm. (2020)
  • Author(s): Md Rasel Molla、清水昭男、佐藤朗、扇田久和
  • Organizer: 日本血管生物医学会若手研究会
• [Presentation] Novel tumor suppressor gene NDRG2 deficiency promotes metabolic disorders and liver cancer development. (2020)
  • Author(s): Tomonaga Ichikawa, Shingo Nakahata, Mitsuru Futakuchi, Ryoji Yamaguchi, Kazuhiro Morishita.
  • Organizer: 第79回日本癌学会
• [Presentation] P2Y1受容体を介したニューロン-アストロサイト-ミクログリア間情報処理機構 (2020)
  • Author(s): 鈴木秀明、繁冨英治、平山幸歩、佐野史和、田中謙二、尾藤晴彦、小泉修一
  • Organizer: 第63回日本神経化学会大会
• [Presentation] Pak1 maintains epidermal stem cells by regulating Langerhans cells and is required for skin carcinogenesis (2020)
  • Author(s): Kazuhiro Okumura, Megumi Saito, Yasuhiro Yoshizawa, Eriko Isogai, Yuichi Wakabayashi
  • Organizer: 第79回日本癌学会総会
• [Presentation] Parameters for cancer-induced sarcopenia in patients autopsied after death from colorectal cancer (2020)
  • Author(s): Mori T, Ohmori H, Luo Y, Kawahara I, Nukaga S, Miyagawa Y, Goto K, Kuniyasu H
  • Organizer: 79th Annual Meeting of Japanese Association for Cancer, Hiroshima, 2020.10.1-3
• [Presentation] PDZD8による小胞体-ミトコンドリアの繋留は骨肉腫細胞においてミトコンドリアの活性を制御する (2020)
  • Author(s): 岸真吾、森汐莉, 谷里奈, 森拓也, 宮川良博, 額賀翔太, 川原勲, 羅奕, 朴木寛容, 國安弘基
  • Organizer: 第109回日本病理学会総会
• [Presentation] Phosphorylation of the Anaphase Promoting Complex activator Cdh1 regulates transition from Meiosis I to Meiosis II in mouse male germ cell (2020)
  • Author(s): Nobuhiro Tanno, Shinji Kuninaka, Sayoko Fujimura, Kaho Okamura, Kimi Araki, Masatake Araki, Hideyuki Saya, Kei-ichiro Ishiguro
  • Organizer: 53rd Annual Meeting of JSDB (Online meeting)
• [Presentation] piRNA biogenesis and function in Drosophila (2020)
  • Author(s): 塩見美喜子
  • Organizer: The Virtual ASBMB Annual Meeting
  • Int'l Joint Research / Invited
• [Presentation] PITX1 is a novel suppressor of SOX10 and inhibit melanoma growth (2020)
  • Author(s): 大平崇人、久郷裕之
  • Organizer: 第79回日本癌学会総会
• [Presentation] Preferential processing of social and reward information by positively-, rather than negatively- responsive neurons in primate amygdala. (2020)
  • Author(s): 倉岡康治, 中村加枝
  • Organizer: 第43回日本神経科学大会
• [Presentation] Preparation and characterization of double-stranded nucleic acid-dependent ATPase activities of tagged Dicer-related helicase 1 in C. elegans (2020)
  • Author(s): 浴 俊彦、小林大士、村上匠蔵、広瀬 侑
  • Organizer: 第43回日本分子生物学会年会
• [Presentation] Quest for claudin-independent occluding junctions in vivo (2020)
  • Author(s): Tetsuhisa Otani, and Mikio Furuse
  • Organizer: 第53回日本発生生物学会年会
• [Presentation] RB1-SUCLA2欠損による代謝脆弱性を標的とした前立腺がん治療法の探索. (2020)
  • Author(s): 河野晋, Paing Linn, 曽我朋義, 高橋智聡.
  • Organizer: 第79回日本癌学会学術総会 2020年10月3日 (広島市/リーガロイヤルホテル広島10/1-3 口頭)
  • Int'l Joint Research
• [Presentation] RhoA confers protection Against Aortic Aneurysm by Preserving Aortic Smooth Muscle Contractility and Preventing Inflammation. (2020)
  • Author(s): Md Rasel Molla、清水昭男、扇田久和
  • Organizer: 日本循環器学会基礎研究フォーラム
• [Presentation] RNA-DNAハイブリッド/G4構造に依存する大腸菌plasmidの複製開始メカニズムの解析 (2020)
  • Author(s): 深津 理乃、田中 卓、正井 久雄
  • Organizer: 第43回日本分子生物学会年会
• [Presentation] Rodent specific 4.5SH RNA is essential for the early development in mouse (2020)
  • Author(s): Ikuko Yamamoto, Michiko Sugimoto, Kimi Araki, Yu Suzuki, Takehiko Kobayashi, Shinichi Nakagawa
  • Organizer: 25th Annual Meeting of the RNA Society
  • Int'l Joint Research
• [Presentation] Role of Intrinsically Disordered Region (IDR) in higher-order brain functions (2020)
  • Author(s): 椎名伸之
  • Organizer: 第43回日本分子生物学会年会
  • Invited
• [Presentation] shRNAスクリーニングによる大腸がん幹細胞の新規治療標的分子経路の探索 (2020)
  • Author(s): 森野峻、馬島哲夫、吉田稔、清宮啓之
  • Organizer: 日本がん分子標的治療学会
• [Presentation] Structural basis of selective interaction between IIa RPTP and Liprin (2020)
  • Author(s): Atsushi Yamagata, Tomoyuki Yoshida, Shuya Fukai
  • Organizer: 第43回 日本神経科学大会
  • Int'l Joint Research
• [Presentation] Suppression of cancer cell growth in mice with a degron system. (2020)
  • Author(s): Chie Naruse, Kazushi Sugihara, Fumihiro Sugiyama, Masahide Asano
  • Organizer: 第43回日本分子生物学会年会
• [Presentation] SWITCHING FROM MITOSIS TO MEIOSIS IS REGULATED BY SEXUALLY DIFFERENT MECHANISM IN MAMMALIAN GERM CELLS (2020)
  • Author(s): Kei-ichiro Ishiguro
  • Organizer: Cold Spring Harbor Laboratory Meeting 2020 GERM CELLS
  • Int'l Joint Research
• [Presentation] The creatine kinase is a metabolic vulnerability in Osteosarcoma. (2020)
  • Author(s): Kishi S, Mori S, Fujiwara-Tani R, Hojo Y, Owar T, Mori T, Nukaga S, Kita M, Sasaki R, Honoki K, Kuniyasu H
  • Organizer: 79th Annual Meeting of Japanese Association for Cancer
• [Presentation] The dual role of PME-1 : PP2A inhibitory protein and methyl-esterase (2020)
  • Author(s): 大浜剛
  • Organizer: The 14th International Conference on Protein Phosphatases
  • Int'l Joint Research / Invited
• [Presentation] The role of GABA in embryonic cortical development (2020)
  • Author(s): Weiru Jiang, Toshikazu Kakizaki, Goichi Miyoshi, Yuchio Yanagawa
  • Organizer: 第67回北関東医学会総会
• [Presentation] The role of PP2A inhibitory protein SET in cancer and its possibility as a drug target. (2020)
  • Author(s): 大浜剛
  • Organizer: 第43回日本分子生物学会年会
• [Presentation] The roles of brain essential fatty acids in dopamine-dependent ingestive behaviors (2020)
  • Author(s): Nobuyuki Sakayori, Kazuto Kobayashi
  • Organizer: 第43回日本神経科学大会
• [Presentation] TMEM180 is involved in proliferation of colorectal cancer cell line SW480 through metabolic pathways (2020)
  • Author(s): Takahiro Anzai, Masahiro Yasunaga, Yasuhiro Matsumura
  • Organizer: 第79回日本癌学会学術総会
• [Presentation] Training-induced Neurosteroids Reinforce Remote Spatial Memory in Mice (2020)
  • Author(s): Kimiko Shimizu, Kanako Maehata, Tomoko Ikeno, Qiuyi WANG, Toshifumi TAKAO and Yoshitaka Fukada
  • Organizer: 第43回日本神経科学大会
• [Presentation] Trametinib preferentially suppresses anchorage-independent growth in osteosarcoma cells and exerts anti-tumor activity (2020)
  • Author(s): 清水孝恒、木村聖美、杉原英志、山口さやか、信末博行、武藤章弘、佐谷秀行
  • Organizer: 第79回日本癌学会学術総会
• [Presentation] trametinibは骨肉腫細胞にapoptosisを誘導し in vivoで抗腫瘍効果を示す (2020)
  • Author(s): 清水孝恒、木村聖美、武藤章弘、佐谷秀行
  • Organizer: 第52回日本臨床分子形態学会総会・学術集会
• [Presentation] Wnt signaling and molecular target therapy (2020)
  • Author(s): Akira Kikuchi
  • Organizer: 第79回日本癌学会学術総会
  • Int'l Joint Research / Invited
• [Presentation] Wnt5a signaling and Colitis-associated tumor formation (2020)
  • Author(s): Akira Kikuchi
  • Organizer: 第79回日本癌学会学術総会
  • Int'l Joint Research / Invited
• [Presentation] アザラメラリンNの合成法の開発 (2020)
  • Author(s): 角真由, 奥谷浄也, 福田勉, 小野寺玄, 木村正成
  • Organizer: 2020年日本化学会九州支部秋期研究発表会
• [Presentation] アストロサイトによる疼痛回路のスクラップ&ビルド (2020)
  • Author(s): 小泉修一
  • Organizer: 新学術領域研究スクラップ&ビルドによる脳機能の動的制御第5回領域会議
• [Presentation] アストロサイト性虚血耐性の分子メカニズム解析 (2020)
  • Author(s): 平山友里、小泉修一、安西尚彦
  • Organizer: 第63回日本神経化学会大会
• [Presentation] アルツハイマー病とアクアポリン4 (2020)
  • Author(s): 阿部陽一郎
  • Organizer: 第20回 日本抗加齢医学会総会
  • Invited
• [Presentation] インダゾール誘導体Lonidamine結合タンパク質の同定と作用機序の解析 (2020)
  • Author(s): 青山愛、藤元次郎、仙波憲太郎
  • Organizer: 第24回日本がん分子標的治療学会学術集会
• [Presentation] うつ病分子病態におけるグリア細胞の異常 (2020)
  • Author(s): 小泉修一
  • Organizer: NPBPPP2020合同年会
• [Presentation] オプトジェネティクスを用いた末梢神経疼痛モデル動物の開発 : NaV1.7を標的とした疼痛モデルマウスの紹介 (2020)
  • Author(s): 丸田豊明, 越田智広, 日髙康太郎, 黒木未央, 白阪哲朗, 恒吉勇男
  • Organizer: 第42回日本疼痛学会
• [Presentation] がん細胞の酸性環境への新規適応機構「acid addiction」の発見 (2020)
  • Author(s): 船戸洋佑、橋爪脩、吉田篤、本田茉子、山崎大輔、三木裕明
  • Organizer: 第93回日本生化学会大会
• [Presentation] グアニン4重鎖/RNA-DNAハイブリッド構造によるDNA複製の制御機構 (2020)
  • Author(s): 正井久雄
  • Organizer: 第93回日本生化学会大会
  • Invited
• [Presentation] グリア研究による脳疾患の解明と創薬を目指して～アストロサイトに魅せられて～ (2020)
  • Author(s): 繁冨英治、小泉修一
  • Organizer: 第13回日本薬学会関東支部若手シンポジウム
• [Presentation] グリア細胞による脳機能の制御 (2020)
  • Author(s): 小泉修一
  • Organizer: 第43回日本神経科学大会
  • Invited
• [Presentation] グルタミン代謝のフェロトーシスを介した虚血腎障害時の役割 (2020)
  • Author(s): 石渡一樹, 鈴木佐和子, 内藤久美子, 出口ハンナ, 類家裕太郎, 石田晶子, 藤本真徳, 田村愛, 志賀明菜, 小出尚史, 石川崇広, 前澤善朗, 田中知明, 横手幸太郎.
  • Organizer: 第93回日本内分泌学会学術総会
• [Presentation] グルタミン代謝の破綻はフェロトーシス依存的に肝癌を増悪させる (2020)
  • Author(s): 鈴木佐和子, 石渡一樹, 内藤久美子, 出口ハンナ, 類家裕太郎, 石田晶子, 藤本真徳, 田村愛, 志賀明菜, 小出尚史, 田中知明, 横手幸太郎.
  • Organizer: 第93回日本内分泌学会学術総会
• [Presentation] ゲノム高次構造制御の破綻による中枢神経回路形成障害 (2020)
  • Author(s): 藤田幸、山下俊英 先生
  • Organizer: 第43回日本神経科学大会
  • Invited
• [Presentation] サルの時間弁別における弁別基準学習への自発運動の影響 (2020)
  • Author(s): 望月 圭, 稲瀬 正彦, 村田 哲
  • Organizer: 第43回日本神経科学大会
• [Presentation] ジーンターゲッティング法によるGATA4-floxマウスの作製 (2020)
  • Author(s): 岩崎亜美・村田康輔・川村名子・中務 胞・阿部 学・夏目里恵・杉村智史・崎村建司・山城秀昭
  • Organizer: 第113回 日本繁殖生物学会
• [Presentation] ショウジョウバエのテロメア構成レトロトランスポゾンはインシュレーター因子であるMod(mdg4)により制御される (2020)
  • Author(s): 竹内 力、岩崎 由香、塩見 春彦
  • Organizer: 第43回日本分子生物学会年会
• [Presentation] ストレス顆粒の新規構成因子およびその生理機能の解析 (2020)
  • Author(s): 吉岡 大介、中村 貴紀、武川 睦寛
  • Organizer: 第43回日本分子生物学会年会
• [Presentation] テロメアから始まるがん創薬 (2020)
  • Author(s): 清宮啓之
  • Organizer: 第24回日本がん分子標的治療学会学術集会
  • Invited
• [Presentation] てんかん原性型グリア細胞の視点によるてんかん分子病態研究 (2020)
  • Author(s): 小泉修一、佐野史和
  • Organizer: 国立精神・神経医療研究センター「てんかんの病態解明と併存症を含めた先駆的・包括的診断と治療方法の開発」第1回研究班会議
• [Presentation] ドーパミン D1受容体を介した神経伝達は、運動制御、嫌悪記憶形成および大脳皮質の Arc活性化に必要である (2020)
  • Author(s): 齊藤 奈英, 田井中 一貴, 知見 聡美, 原 怜, 山口 瞬, 一瀬 宏, 南部 篤, 笹岡 俊邦
  • Organizer: 第43回日本神経科学大会
• [Presentation] トポイソメラーゼ阻害剤のがん治療感受性機構の検討 (2020)
  • Author(s): 中村 清志朗、河原 康一、古川 龍彦
  • Organizer: 日本薬学会 第141年会
• [Presentation] トリソミー8生体モデルによる+8造血幹細胞機能の解析 (2020)
  • Author(s): 指田吾郎
  • Organizer: 第43回日本分子生物学会
  • Invited
• [Presentation] ニューロンのレゾナンス特性におけるKvll電位依存性 K+チャネルの機能的役割 (2020)
  • Author(s): 松岡 利典, 山﨑 美和子, 阿部 学, 松田 由喜子, 森野 豊之, 川上 秀史, 崎村 健司, 渡辺 雅彦, 橋本 浩一
  • Organizer: 第43回 日本神経科学学会大会
• [Presentation] ヒトRiflC末領域はその核膜局在と複製タイミング制御に必要とされる (2020)
  • Author(s): 伊藤 さゆり、井口 智弘、覺正 直子、大字 亜沙美、平谷 伊智朗、正井 久雄
  • Organizer: 第43回日本分子生物学会年会
• [Presentation] マウスプラセボ鎮痛条件づけを用いたプラセボ応答の分子基盤の探索 (2020)
  • Author(s): 岸本 泰司, 中村 裕子, 新開 崇広, 青野 仁美, 藤原 友佳, 大畑 南美, 松崎 真也, 山本 融
  • Organizer: 第43回日本神経科学大会
• [Presentation] ミクログリアの自己再生によるアレキサンダー病の抑制 (2020)
  • Author(s): 小林憲司、繁冨英治、パラジュリビージェイ、久保田友人、齋藤光象、田中謙二、池中一裕、小泉修一
  • Organizer: 第63回日本神経化学会大会
• [Presentation] ミクログリア制御と脳機能 (2020)
  • Author(s): 小泉修一
  • Organizer: 第63回日本神経化学会大会
• [Presentation] ユニークな三次元構造を持つアルカロイドの全合成と構造活性相関 (2020)
  • Author(s): 塚野千尋
  • Organizer: 京都大学生理化学研究ユニット 第10回シンポジウム
  • Invited
• [Presentation] ラットモデルを用いたNrf2活性化が引き起こす病態の解明 (2020)
  • Author(s): 田口恵子、山本雅之
  • Organizer: 第19回分子予防環境医学研究会大会
  • Invited
• [Presentation] ランゲルハンス細胞のPak1遺伝子 (2020)
  • Author(s): 奥村和弘、斎藤慈、若林雄一
  • Organizer: 第79回日本癌学会学術総会
• [Presentation] リン酸化プロテオーム解析から発見した新規神経成長・再生マーカー (2020)
  • Author(s): 岡田正康, 河嵜麻実, 玉田篤史, 棗田学, 大石誠, 藤井幸彦, 五十嵐道弘
  • Organizer: 第30回日本サイトメトリー学会
• [Presentation] リン脂質フォスファターゼを介した軸索側枝形成の分子機構 (2020)
  • Author(s): 安村美里、猪口徳一、谷口学、Mai Quynh Nguyen、佐藤真
  • Organizer: 日本神経科学大会
• [Presentation] 悪性黒色腫におけるGREB1 isoform 4の発現機構解析とがん治療への応用 (2020)
  • Author(s): 新沢康英, 松本真司、種村篤、藤本学、菊池 章
  • Organizer: 第93回日本生化学会大会
• [Presentation] 加齢ストレスによるMLL-AF9幹細胞の転写機構障害と白血病発症抑制機序 (2020)
  • Author(s): 前田彩華、久保田翔、横溝貴子、飯盛美穂子、荒木喜美、大里元美、指田吾郎
  • Organizer: 第82回日本血液学会
• [Presentation] 快楽的摂食行動に対する脳内必須脂肪酸の役割の解析 (2020)
  • Author(s): 酒寄信幸, 小林和人
  • Organizer: 第5回食欲・食嗜好の分子・神経基盤研究会
• [Presentation] 核小体ストレス応答によりP53経路を活性化する新たながん分子標的治療薬の創生 (2020)
  • Author(s): 河原 康一、古川 龍彦
  • Organizer: 第79回日本癌学会学術総会
• [Presentation] 褐色脂肪によるアンチエージング (2020)
  • Author(s): 清水逸平
  • Organizer: 抗加齢医学会
  • Invited
• [Presentation] 感染記憶による骨髄異形成症候群の発症機序解析 (2020)
  • Author(s): 指田吾郎、横溝貴子、久保田翔、濱嶋愛、金井昭教、岩間厚志、滝澤仁、松井啓隆
  • Organizer: 第82回日本血液学会
• [Presentation] 基礎医学研究の魅力-日本神経化学会理事長から- (2020)
  • Author(s): 小泉修一
  • Organizer: 第61回日本神経学会学術大会
  • Invited
• [Presentation] 機能的なリガンドならびにレセプター遺伝子を標的とした新たなコンデショナルレスキューマウスの作成 (2020)
  • Author(s): 渡邉 大介
  • Organizer: 第43回日本分子生物学会年会
• [Presentation] 強い抗がん選択性を持つ新規合成ラメラリン類縁体 Azalam4の抗がんメカニズム解析 (2020)
  • Author(s): 大橋愛美, 福田勉, 岡村睦美, 西谷直之, 岩尾正倫, 旦慎吾
  • Organizer: 第79回日本癌学会学術総会
• [Presentation] 強い抗がん特異性を示しCDKを阻害する新規ラメラリン類縁体Azalam4の同定 (2020)
  • Author(s): 大橋愛美, 福田勉, 岡村睦美, 西谷直之, 岩尾正倫, 旦慎吾
  • Organizer: 第24回日本がん分子標的治療学会学術集会
• [Presentation] 空間記憶形成の日周リズムとニューロステロイドによる制御 (2020)
  • Author(s): 清水貴美子、前畑佳納子、Qiuyi Wang、池野知子、衛澤峰、櫻井文香、Yue Pan、高尾敏文、深田吉孝
  • Organizer: 第27回日本時間生物学会学術大会
  • Invited
• [Presentation] 減数分裂開始に必須の役割を果たすMEIOSINおよびSTRA8のタンパク質ドメイン (2020)
  • Author(s): 石黒 啓一郎
  • Organizer: 第43回 日本分子生物学会年会(MBSJ2020)online
  • Invited
• [Presentation] 古い記憶想起における海馬歯状回記憶痕跡細胞の関与 (2020)
  • Author(s): 奥野浩行
  • Organizer: 第63回日本神経化学会大会
  • Invited
• [Presentation] 甲状腺未分化癌細胞におけるlenvatinibとIRAK1/4 inhibitor Iの併用効果の検討 (2020)
  • Author(s): 川村佳史、西條憲、今井源、石岡千加史
  • Organizer: 日本がん分子標的治療学会
• [Presentation] 高眼圧性緑内障はP2Y1受容体の機能障害によって誘導される (2020)
  • Author(s): 濱田健太郎、篠崎陽一、行方和彦、大野伸彦、瀬川高弘、原田高幸、柏木賢治、小泉修一
  • Organizer: 第63回日本神経化学会大会
• [Presentation] 細胞系譜追跡による造血幹細胞・前駆細胞の発生様式の解析 (2020)
  • Author(s): 横溝智雅, 井手上社子, 荒木喜美, 黒川峰夫, 小松則夫, 大里元美, 須田年生
  • Organizer: 第82回日本血液学会
• [Presentation] 時間の知覚と生成に関わるサル前頭前野の神経細胞活動 (2020)
  • Author(s): 千葉 惇, 守田 和紀, 高良 沙幸, 生塩 研一, 稲瀬 正彦
  • Organizer: 第43回日本神経科学大会
• [Presentation] 時計遺伝子のシス制御エレメントが個体の活動や生理リズムの維持に与える影響の範囲・限界 (2020)
  • Author(s): 土居雅夫
  • Organizer: 第43回日本分子生物学会年会
• [Presentation] 腫瘍細胞優先的にP53経路を活性する新たな機構の解明とがん分子標的治療薬の開発の試み (2020)
  • Author(s): 河原 康一、古川 龍彦
  • Organizer: 第41回日本臨床薬理学会学術総会
  • Invited
• [Presentation] 小細胞肺がんの悪性化における細胞接着因子CADM1の機能解析 (2020)
  • Author(s): 舩城桐子、村上善則、伊東剛
  • Organizer: 第79回日本癌学会学術総会
• [Presentation] 小脳抑制性介在ニューロンルガロ細胞の帯状構造特異的な入出力様式 (2020)
  • Author(s): 宮﨑 太輔、山崎 美和子、渡辺 雅彦
  • Organizer: 第66回東北・北海道連合支部学術集会
• [Presentation] 小胞体-ミトコンドリア繋留分子PDZD8の抑制は胃癌に細胞死をもたらす (2020)
  • Author(s): 北條雄大、岸 真五、森 汐莉、谷 里奈、篠原 尚、國安弘基
  • Organizer: 第109回日本病理学会総会
• [Presentation] 上皮バリアの構築機構 (2020)
  • Author(s): 大谷哲久、古瀬幹夫
  • Organizer: 第10回名古屋大学大学院医学系研究科-生理学研究所合同シンポジウム
• [Presentation] 心臓、骨格筋における老化促進代謝物質の病的意義の解明 (2020)
  • Author(s): 清水逸平
  • Organizer: 第26回日本心臓リハビリテーション学会学術集会
  • Invited
• [Presentation] 神経幹細胞特異的Itpaノックアウトマウスは神経細胞脱分極とてんかん様けいれん発作を示し、早期に死亡する (2020)
  • Author(s): 土本大介、古賀祐一郎、林良憲、アボルハッサニ ノナ、米嶋康臣、作見邦彦、中西博、豊國伸哉、中別府雄作
  • Organizer: 第43回日本神経科学大会
• [Presentation] 神経障害性疼痛アロディニア誘導のメカニズム (2020)
  • Author(s): 小泉修一
  • Organizer: 第84回日本皮膚科学会東部支部学術大会
  • Invited
• [Presentation] 進行前立腺がんにおけるRB1-SUCLA2遺伝子欠失を標的とする新規治療. (2020)
  • Author(s): 髙橋智聡, Paing Linn, 曽我朋義, 河野晋.
  • Organizer: 第58回日本癌治療学会学術総会 2020年10月23日 (京都市/国立京都国際会館 10/22-24 口頭)
• [Presentation] 正常眼圧緑内障モデルマウス視神経乳頭部における早期グリア活性化 (2020)
  • Author(s): 篠崎陽一、行方和彦、柏木賢治、大野伸彦、原田高幸、小泉修一
  • Organizer: 第143回日本薬理学会関東部会
• [Presentation] 青斑核ノルアドレナリン神経細胞の活動亢進による情動記憶の想起の促進 : 新規神経活動活性化ツールによる検討 (2020)
  • Author(s): 井口善生・深堀良二・...・小林和人
  • Organizer: 第52回東北生理談話会.
• [Presentation] 脊髄におけるBEGAIN陽性介在ニューロンの可視化 (2020)
  • Author(s): 片野泰代(発表代表者、責任発表者), 阿部学, 渡辺雅彦, 崎村建司, 伊藤誠二, 小林拓哉
  • Organizer: 第43回日本神経科学大会
• [Presentation] 染色体工学技術を利用したイノベーション創出-基礎から応用研究を通して- (2020)
  • Author(s): 久郷裕之
  • Organizer: 第20回日本抗加齢医学会総会
  • Invited
• [Presentation] 染色体工学技術を利用した革新的癌研究 -基礎から応用研究への展開 (2020)
  • Author(s): 久郷裕之
  • Organizer: 第27回日本がん予防学会総会
  • Invited
• [Presentation] 多段階皮膚発がんマウスモデルを用いたがん (2020)
  • Author(s): 奥村和弘
  • Organizer: 第67回日本実験動物学会総会
• [Presentation] 体内時計の温度同調機構 : 生理的な範囲の温度変化が培養マウス繊維芽細胞の分子時計に与える影響について (2020)
  • Author(s): 井ノ上 雄一、三宅 崇仁、土居 雅夫
  • Organizer: 第43回日本分子生物学会年会
• [Presentation] 胎生期過栄養誘発脂肪肝炎/肝癌 : HIF-1シグナル系の役割 (2020)
  • Author(s): 滝山貴央、世良俊博、中村匡徳、堀家慎一、西川祐司、滝山由美
  • Organizer: 第35回日本糖尿病合併症会学
• [Presentation] 胎生期高脂肪食誘発-脂肪肝炎-肝癌モデルマウスの確立 (2020)
  • Author(s): 滝山貴央、滝山由美、別所瞭一、橘内博哉、竹田安孝、坂上英充、西川祐司、竹内文也、世良俊博、中村匡徳
  • Organizer: 第63回日本糖尿病学会年次学術総会
• [Presentation] 大腸菌におけるゲノム上のRNA-DNA hybrid・グアニン4重鎖構造のプロファイルと第二の複製系での役割の解明 (2020)
  • Author(s): 鷺 朋子、田中 卓、正井 久雄
  • Organizer: 第43回日本分子生物学会年会
• [Presentation] 大脳基底核間接路のD2受容体発現細胞における NMDA受容体のマグネシウムブロックの減少により誘導される運動制御と学習記憶の変化の解析 (2020)
  • Author(s): 笹岡 俊邦, 齊藤 奈英, 知見 聡美, 阿部 学, 川村 名子, 鍋島 陽一, 田井中 一貴, 﨑村 建司, 南部 篤
  • Organizer: 第43回日本神経科学大会
• [Presentation] 大脳皮質グリア細胞による神経障害性疼痛の誘導 (2020)
  • Author(s): 小泉修一
  • Organizer: 日本ペインクリニック学会学術集会
  • Invited
• [Presentation] 痛みの精密医療への臨床からの挑戦 (2020)
  • Author(s): 住谷昌彦、西澤大輔、池田和隆
  • Organizer: 日本疼痛学会
  • Invited
• [Presentation] 転写因子Trps1の発現制御機構 (2020)
  • Author(s): 佐伯直哉、立田咲百合、波多賢二、阿部真土
  • Organizer: 第38回日本骨代謝学会学術集会
• [Presentation] 頭蓋内移植手法によるHER2陽性乳がんの脳組織中における増殖能の評価 (2020)
  • Author(s): 黒岩由佳, 中山淳, 仙波憲太郎
  • Organizer: 第72回日本細胞生物学会大会
• [Presentation] 頭蓋内移植手法によるHER2陽性乳がん細胞株の増殖分類(Proliferative classification of HER2-positive breast cancer cell lines by intracranial injection.) (2020)
  • Author(s): 黒岩由佳, 中山淳, 山本雄介, 仙波憲太郎
  • Organizer: 2020年度文部科学省新学術領域研究 先端モデル動物支援プラットフォーム 若手支援技術講習会
• [Presentation] 頭蓋内移植手法によるHER2陽性乳がん細胞株の脳転移能の解析 (2020)
  • Author(s): 黒岩由佳, 中山淳, 仙波憲太郎
  • Organizer: 第29回日本がん転移学会学術集会・総会
• [Presentation] 同所性移植手法を用いた乳がん肺転移株のシグナル解析 (2020)
  • Author(s): 林 祐介, 中山 淳, 山本 瑞生, 山本 雄介, 井上 純一郎, 仙波 憲太郎
  • Organizer: 第79回日本癌学会学術総会
• [Presentation] 同所性移植手法を用いた乳がん肺転移株のシグナル解析 (2020)
  • Author(s): 林 祐介, 中山 淳, 仙波 憲太郎
  • Organizer: 第72回日本細胞生物学会大会
• [Presentation] 銅触媒作用による三成分連結反応を介したオキサボロールの合成 (2020)
  • Author(s): 末吉巽, 布田旭, 福田勉, 小野寺玄, 木村正成
  • Organizer: 第49回複素環化学討論会
• [Presentation] 突然変異型MFN2の時期特異的発現調節による神経変性の病態比較 (2020)
  • Author(s): 石川 香、山本 智、服部 聡子、西村 尚也、松本 寛和、宮川 剛、中田 和人
  • Organizer: 第43回日本分子生物学会
• [Presentation] 軟骨細胞分化のエピジェネティクス機構 (2020)
  • Author(s): 波多賢二
  • Organizer: 第33回日本軟骨代謝学会
  • Invited
• [Presentation] 乳がん肺高転移株における殺細胞性抗がん剤耐性機構と細胞増殖機構の解明 (2020)
  • Author(s): 林 祐介, 中山 淳, 仙波 憲太郎
  • Organizer: 第29回日本がん転移学会学術集会・総会
• [Presentation] 乳がん肺高転移株における殺細胞性抗がん剤耐性機構と細胞増殖機構の解明 (2020)
  • Author(s): 林 祐介, 中山 淳, 仙波 憲太郎
  • Organizer: 第24回日本がん分子標的治療学会学術総会
• [Presentation] 妊娠中の偏った必須脂肪酸摂取は子においてドパミン依存的摂食行動を促す (2020)
  • Author(s): 酒寄信幸, 小林和人
  • Organizer: 日本脂質栄養学会第29回大会
• [Presentation] 妊娠中の偏った必須脂肪酸摂取は子において快楽的摂食を促す (2020)
  • Author(s): 酒寄信幸, 小林和人
  • Organizer: 第53回日本栄養・食糧学会中国・四国支部大会
• [Presentation] 脳虚血障害におけるミクログリアVNUTの役割 (2020)
  • Author(s): 平山友里、Le Pham Ngoc Ha、小泉修一、安西尚彦
  • Organizer: 第142回日本薬理学会関東部会
• [Presentation] 脳神経機能における 相分離RNA顆粒の役割 (2020)
  • Author(s): 椎名伸之
  • Organizer: 日本植物学会第84回大会
  • Invited
• [Presentation] 脳組織中での増殖能に基づくHER2陽性乳がん細胞株の分類(Classification of HER2-positive breast cancer cell lines based on the proliferative activity in the brain) (2020)
  • Author(s): 黒岩由佳, 中山淳, 足立ちひろ, 井上貴文, 山本雄介, 渡辺慎哉, 仙波憲太郎
  • Organizer: 第43回日本分子生物学会年会
• [Presentation] 脳組織中における増殖能に基づくHER2陽性乳がん細胞株の分類(Classification of HER2-positive breast cancer cell lines based on proliferative activity in brain tissue) (2020)
  • Author(s): 黒岩由佳, 中山淳, 山本雄介, 渡辺慎哉, 仙波憲太郎
  • Organizer: 第79回日本癌学会学術総会
• [Presentation] 脳内サーカディアンリズム中枢を制御する時間選択的Gタンパク質シグナル伝達経路GPR176-Gz-RGS16の役割 (2020)
  • Author(s): 土居雅夫
  • Organizer: 第93回日本生化学会大会
  • Invited
• [Presentation] 非定型型直鎖状ユビキチン鎖を足場とするNF-кB活性化の細胞機能と数理モデル (2020)
  • Author(s): 徳永文稔、及川大輔、畑中尚也、鈴木貴
  • Organizer: 第93回日本生化学会大会
  • Invited
• [Presentation] 必須脂肪酸は中脳ドパミンニューロン産生を制御し将来の快楽的摂食を調節する (2020)
  • Author(s): 酒寄信幸, 小林和人
  • Organizer: 第93回日本生化学会大会
• [Presentation] 標的既知化合物スクリーニングによる酸性環境適応におけるTGF-β経路の重要性の解明 (2020)
  • Author(s): 本田茉子、船戸洋佑、三木裕明
  • Organizer: 第43回日本分子生物学会年会
• [Presentation] 腹側海馬アストロサイトにおけるGqPCRシグナルがマウス行動に与える影響 (2020)
  • Author(s): 繁冨英治、小泉修一
  • Organizer: 第63回日本神経化学会大会
• [Presentation] 分泌性タンパク質p53PAD7とHippoシグナル経路による増殖抑制機構の解明. (2020)
  • Author(s): 滝川 雅大、渡邉 祐三、岡部 篤史、金田 篤志、石川 冬木、定家 真人、大木 理恵子
  • Organizer: 第79回日本癌学会学術総会
• [Presentation] 膜電位感受性プローブの開発とその応用 (2020)
  • Author(s): 坂本 雅行
  • Organizer: 鹿児島大学セミナー
  • Invited
• [Presentation] 味覚連合記憶の想起における青斑核ノルアドレナリン細胞の役割-ハエ嗅覚器由来のイオンチャネルを利用した新規神経活動活性化ツールによる検討- (2020)
  • Author(s): 井口善生
  • Organizer: 生理研研究会2020・行動の多様性を支える神経基盤とその動作様式の解明
  • Invited
• [Presentation] 密着結合の構造と機能の再考 (2020)
  • Author(s): Tetsuhisa Otani, Thanh Phuong Nguyen, Mikio Furuse
  • Organizer: 第43回日本分子生物学会年会
  • Invited
• [Presentation] 網羅的遺伝子発現解析による胃がんの発生・進展の理解 (2020)
  • Author(s): 大上直秀, 山本悠司, 浅井竜一, 國安弘基, 仙谷和弘, 坂本直也, 大段秀樹, 吉田和弘, 安井弥
  • Organizer: 第109回日本病理学会総会
  • Invited
• [Presentation] 緑内障病態におけるグリア細胞と網膜神経節細胞死 (2020)
  • Author(s): Koizumi S
  • Organizer: 第31回日本緑内障学会
  • Invited
• [Presentation] 老化関連疾患の克服による健康寿命の延伸 (2020)
  • Author(s): 山縣和也
  • Organizer: 第70回日本体質医学会総会
  • Invited
• [Presentation] 老化促進分子による加齢同期メカニズムの解明 (2020)
  • Author(s): 清水逸平
  • Organizer: 第62回日本老年医学会学術集会
  • Invited
• [Presentation] 老化促進分子による加齢同期メカニズムの解明 (2020)
  • Author(s): 清水逸平
  • Organizer: 第41回日本炎症・再生医学会
  • Invited
• [Presentation] 老化促進分子を標的とした次世代の心不全治療法開発に向けた取り組み (2020)
  • Author(s): 清水逸平
  • Organizer: 第257回日本循環器学会関東甲信越地方会
  • Invited
• [Presentation] 膵β細胞と低酸素ストレス (2020)
  • Author(s): 山縣和也
  • Organizer: 第58回日本糖尿病学会九州地方会
  • Invited
• [Presentation] 膵β細胞における代償性インスリン過剰分泌破綻の分子機構の解析 (2020)
  • Author(s): 青柳共太、山下俊一、西脇知世乃、中道洋子、神吉智丈、今泉美佳
  • Organizer: 第63回日本糖尿病学会年次学術集会
• [Presentation] 膵β細胞分化におけるGlutaminase 2の役割解明 (2020)
  • Author(s): 出口ハンナ、鈴木佐和子、田中知明、横手幸太郎
  • Organizer: 第93回日本内分泌学会学術総会
• [Book] Optogenetics - Light-Sensing Proteins and Their Applications in Neuroscience and Beyond (2021)
  • Author(s): Yawo, H., Kandori, H., Koizumi, A., Kageyama, R. (Eds.)
  • Total Pages: 663
  • Publisher: Springer Nature
• [Book] マウス・ラットモデル作成・解析プロフェッショナル (2021)
  • Author(s): 室井誠、馬島哲夫、牛嶋大、松浦正明, ほか
  • Total Pages: 320
  • Publisher: 羊土社
• [Book] がん幹細胞と薬剤耐性「治療標的としてのがん幹細胞」 別冊・医学のあゆみ (2021)
  • Author(s): 馬島哲夫, 清宮啓之
  • Total Pages: 132
  • Publisher: 医歯薬出版株式会社
• [Book] がん診療の副作用マネジメント Management of adverse effects of cancer therapy 研究者の最新動向・重粒子線治療に伴う副作用の予測と軽減技術 (2020)
  • Author(s): 大神 正次・高井 伸彦
  • Total Pages: 100
  • Publisher: 北隆館
• [Book] 体細胞分裂から減数分裂へのスイッチ機構 月刊「細胞」8月号 (2020)
  • Author(s): 石黒啓一郎
  • Total Pages: 62
  • Publisher: ニューサイエンス社
• [Book] 減数分裂開始因子MEIOSINとその標的遺伝子の変異による不妊 BIO Clinica (2020)
  • Author(s): 石黒啓一郎
  • Total Pages: 94
  • Publisher: 北隆館
• [Book] 生殖細胞の運命決定 -体細胞分裂から減数分裂への細胞周期の切替え 実験医学5月号 (2020)
  • Author(s): 石黒啓一郎
  • Total Pages: 139
  • Publisher: 羊土社
• [Book] 相分離生物学の全貌 「RNP顆粒研究を加速するトランスクリプトーム解析技術」 (2020)
  • Author(s): 七野悠一、岩崎信太郎
  • Total Pages: 416
  • Publisher: 東京化学同人
• [Book] 体細胞分裂と減数分裂における染色体・クロマチン構造の違い 月刊「細胞」5月増刊号 (2020)
  • Author(s): 石黒啓一郎
  • Total Pages: 60
  • Publisher: ニューサイエンス社
• [Book] 体内時計の中枢を調節するG蛋白質共役型受容体 膜タンパク質工学ハンドブック (2020)
  • Author(s): 嶋谷 寛之、土居 雅夫
  • Total Pages: 624
  • Publisher: エヌ・ティー・エス出版
• [Book] 不妊の原因に関わる新規遺伝子MEIOSIN 週刊医学のあゆみvol.275 (2020)
  • Author(s): 石黒啓一郎
  • Total Pages: 70
  • Publisher: 医歯薬出版
• [Remarks] 先端モデル動物支援プラットフォーム(AdAMS)ホームページ
  • URL: http://model.umin.jp/
• [Remarks] 北海道大学大学院薬学研究院生化学研究室ホームページ
  • URL: http://www.pharm.hokudai.ac.jp/seika/index.html
• [Remarks] 北海道大学遺伝子病制御研究所分子腫瘍分野ホームページ
  • URL: http://www.igm.hokudai.ac.jp/oncology/
• [Remarks] 東北大学 大学院医学系研究科 医化学分野ホームページ
  • URL: http://www.dmbc.med.tohoku.ac.jp/official/index.html
• [Remarks] 福島県立医科大学研究成果情報ページ
  • URL: https://www.fmu.ac.jp/univ/kenkyuseika/research/1709.html
• [Remarks] 筑波大学 医学医療系 生命医科学域 解剖学・神経科学研究室
  • URL: http://www.kansei.tsukuba.ac.jp/~takeilab/
• [Remarks] 理化学研究所RNAシステム生化学研究室 岩崎研究室ホームページ
  • URL: http://iwasakirna.com/
• [Remarks] 理化学研究所RNAシステム生化学研究室 岩崎研究室ホームページ
  • URL: http://www.riken.jp/research/labs/chief/rna_sys_biochem/
• [Remarks] 千葉大学大学院医学研究院 内分泌代謝・血液・老年内科学ホームページ
  • URL: https://www.m.chiba-u.ac.jp/dept/clin-cellbiol/research/diabetic/study_05/
• [Remarks] 千葉大学大学院医学研究院 内分泌代謝・血液・老年内科学ホームページ
  • URL: https://www.m.chiba-u.ac.jp/dept/clin-cellbiol/research/diabetic/study_04/
• [Remarks] 東京工業大学生命理工学院 一瀬研究室ホームページ
  • URL: http://www.bh4.bio.titech.ac.jp/index.html
• [Remarks] 東京慈恵会医科大学 総合医科学研究センター渡部研究部ホームページ
  • URL: http://watabe-lab.jp/
• [Remarks] 東京農工大学大学院工学研究院応用化学分野 大栗研究室ホームページ
  • URL: http://web.tuat.ac.jp/~h_oguri/index.html
• [Remarks] 公益財団法人微生物化学研究所
  • URL: https://www.bikaken.or.jp
• [Remarks] 慶應義塾大学薬学部生化学講座ホームページ
  • URL: http://square.umin.ac.jp/keio-dbc/research.html
• [Remarks] 順天堂大学 医学部 小松雅明研究室ホームページ
  • URL: https://www.juntendo.ac.jp/graduate/laboratory/labo/kikan_saibou/
• [Remarks] 新学術領域研究マルチモードオートファジーホームページ
  • URL: http://proteolysis.jp/multimode_autophagy/
• [Remarks] 新潟大学脳研究所 動物資源開発研究分野 ホームページ
  • URL: http://www.bri.niigata-u.ac.jp/field/lab_animal/index.html
• [Remarks] 新潟大学脳研究所 脳研コラム ホームページ
  • URL: http://www.bri.niigata-u.ac.jp/result/lab_animal/000126.html
• [Remarks] 新潟大学脳研究所 研究成果・実績 ホームページ
  • URL: http://www.bri.niigata-u.ac.jp/result/lab_animal/000833.html
• [Remarks] 新潟大学大学院医歯学総合研究科機能制御学分野のホームページ
  • URL: https://www.med.niigata-u.ac.jp/mit/
• [Remarks] 新潟大学脳研究所 研究業績ホームページ
  • URL: http://www.bri.niigata-u.ac.jp/result/surgery/001033.html
• [Remarks] 富山大学薬学部分子神経生物学研究室ホームページ
  • URL: http://www.pha.u-toyama.ac.jp/biochel/index-j.html
• [Remarks] 金沢大学広報ホームページ
  • URL: https://www.kanazawa-u.ac.jp/latest-research/64909
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  • URL: https://www.scl.kyoto-u.ac.jp/~uesugi/ja/index.php
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  • URL: https://www2.med.osaka-u.ac.jp/mds/
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  • URL: http://molimm.biken.osaka-u.ac.jp
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  • URL: http://osaka-cu-lseika.umin.jp/
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  • URL: http://www.kmu.ac.jp/faculty/medical/category2/unit4.html
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  • URL: http://www.cyber.biotech.okayama-u.ac.jp/senolab/
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  • URL: https://home.hiroshima-u.ac.jp/physio12/index.html
• [Remarks] 香川大学医学部薬理学研究室ホームページ
  • URL: http://www.kms.ac.jp/~yakuri/
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  • URL: http://www.bioreg.kyushu-u.ac.jp/saibou/index.html
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  • URL: http://shuyo.phar.kyushu-u.ac.jp/
• [Remarks] 福岡大学てんかん分子病態研究所ホームページ
  • URL: http://www.med.fukuoka-u.ac.jp/epilepsy/index.html
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  • URL: http://egtc.jp
• [Remarks] 熊本大学発生医学研究所ホームページ
  • URL: http://www.imeg.kumamoto-u.ac.jp/np104/
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  • URL: http://ncmac2.es.hokudai.ac.jp/index.html
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  • URL: http://www.dmbc.med.tohoku.ac.jp/official/index.html
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  • URL: http://www.biol.tsukuba.ac.jp/nakada_ishikawa/index.html
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  • URL: https://www1.niu.ac.jp/topics/study/2020/3429.html
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• [Remarks]
• [Remarks]
• [Patent(Industrial Property Rights)] がんの治療又は予防剤、及びがんの治療又は予防のためのRF経路阻害剤とMEK阻害剤との組み合わせ (2021)
  • Inventor(s): 大塩貴子、園下将大、市川聡、佐藤悠介、藤井清永
  • Industrial Property Rights Holder: 大塩貴子、園下将大、市川聡、佐藤悠介、藤井清永
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 特願2021-29585
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  • Inventor(s): 園下将大、関谷翔、平野聡
  • Industrial Property Rights Holder: 園下将大、関谷翔、平野聡
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: PCT/JP2021/7651
  • Overseas
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  • Inventor(s): 長澤和夫、松田未沙子、馬悦、清宮啓之
  • Industrial Property Rights Holder: 国立大学法人東京農工大学、公益財団法人がん研究会
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 特願2020-008592
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  • Inventor(s): 長澤和夫、馬悦
  • Industrial Property Rights Holder: 東京農工大学
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 特願2020-021316
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  • Inventor(s): 山村研一、岩脇隆夫、及川大輔、石川智夫
  • Industrial Property Rights Holder: 株式会社トランスジェニック
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: US10765094
  • Overseas
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  • Inventor(s): 河原康一、古川龍彦、下川倫子、川畑拓斗、白石岳大、浜崎研吾
  • Industrial Property Rights Holder: 鹿児島大学
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 第6779517号