先端モデル動物支援プラットフォーム

2021 Fiscal Year Annual Research Report

• Project/Area Number: 16H06276
• Principal Investigator: 井上 純一郎 東京大学, 医科学研究所, 特任研究員
• Project Period (FY): 2016 – 2021
• Keywords: モデル動物作製 / ゲノム編集 / 病理形態解析 / 生理機能解析 / 分子探索・プロファイリング

Outline of Annual Research Achievements

①総括支援活動 : 若手技術講習会を9月6日にオンライン開催した。93名の参加があり、若手研究者がグループセッションをリードする企画が好評を博した。成果発表会は2月2～3日に滋賀県琵琶湖の会場とウェブによるハイブリッド形式で開催し201名の参加があった。被支援者による研究成果の紹介を中心に、充実した質疑応答が行われた。
②モデル動物作製支援活動 : 前・後期2回の公募では、118件の応募があり、うち70件についてプレコンサルテーションを行った。審査の結果83件が採択された。それぞれの採択者と個別に協議し、最適な遺伝子改変技術を用いて、遺伝子改変マウスおよびラットを迅速に作製し、研究リソースとして提供した。
③病理形態解析支援活動 : マウスやラットなど実験動物個体に認める病的所見やその治療効果を、H&E染色や免疫染色など主に光学顕微鏡を使用する解析技術を駆使して表現系を解釈する支援活動を実施した。46件の申請を受け、36件を採択した。解剖、標本作製、レーザーマイクロダイセクションなど多彩な解析を行い、論文の投稿・改訂も支援した。
④生理機能解析支援活動 : 全体で57件の申請があり、行動学的解析27件、薬理学的解析13件、光技術による操作解析2件、多機能電極・計測データ解析14件、計56件を採択した。支援は、動物モデルにおける病態・生理学的基盤の解明推進などに寄与し、Nat Commun誌などに成果が発表された。
⑤分子プロファイリング支援活動 : 全体で130件(のべ656回)の申請に対し、化合物の分子プロファイリング67件、阻害剤キット配付25件、RNA干渉キット配付・siRNAデザイン合成8件、shRNAライブラリー探索3件、計103件(のべ530回)を採択。加えて、高次情報解析等の技術相談を行い、動物モデル研究の起点となる生理機能制御分子の発見・創出などに繋がった。

Research Progress Status

令和3年度が最終年度のため記入しない

Strategy for Future Research Activity

令和3年度が最終年度のため記入しない

Research Products

• [Int'l Joint Research] Howard University/National Institutes of Health/Fred Hutchison Cancer Center(米国)
  • Country Name: U.S.A.
  • Counterpart Institution: Howard University/National Institutes of Health/Fred Hutchison Cancer Center
  • # of Other Institutions: 2
• [Int'l Joint Research] University of British Columbia/Dalhousie University/York University(カナダ)
  • Country Name: CANADA
  • Counterpart Institution: University of British Columbia/Dalhousie University/York University
• [Int'l Joint Research] Sorbonne University(フランス)
  • Country Name: FRANCE
  • Counterpart Institution: Sorbonne University
• [Journal Article] Chemical components from Hedera rhombea leaves and their cytotoxicity (2022)
  • Author(s): Akihito Yokosuka, Tatsuya Shimomura, Shohei Yokogawa, Airi Oguro, Katsunori Miyake, Yoshihiro Mimaki
  • Journal Title: Chemical and Pharmaceutical Bulletin Volume: 70 Pages: 175-181
  • DOI: 10.1248/cpb.c21-00907
  • Peer Reviewed / Open Access
• [Journal Article] D1 Receptor Mediated Dopaminergic Neurotransmission Facilitates Remote Memory of Contextual Fear Conditioning (2022)
  • Author(s): Nae Saito, Makoto Itakura, Toshikuni Sasaoka
  • Journal Title: Frontiers in Behavioral Neuroscience Volume: 16 Pages: 751053
  • DOI: 10.3389/fnbeh.2022.751053
  • Peer Reviewed / Open Access
• [Journal Article] D1およびD2ドーパミン受容体を介する神経伝達による運動制御と学習記憶の仕組みの理解 (2022)
  • Author(s): 齊藤奈英、板倉誠、田井中一貴, Tom Macpherson, 疋田貴俊、山口瞬、佐藤朝子、大久保直、知見聡美、南部篤、笹岡俊邦
  • Journal Title: 日本生物学的精神医学会誌 Volume: 33
• [Journal Article] Elucidation of structure-activity relationship of humulanolides and identification of humulanolide analog as a novel HSP90 inhibitor. (2022)
  • Author(s): Saegusa J, Osada Y, Miura K, Sasazawa Y, Ogura A, Takao KI, Simizu S.
  • Journal Title: Bioorg Med Chem Lett Volume: 60 Pages: 128589
  • DOI: 10.1016/j.bmcl.2022.128589
  • Peer Reviewed
• [Journal Article] Establishment of a long-term survival swine model for observation of transplanted islets : A preliminary step in an allogeneic transplant experiment. (2022)
  • Author(s): Miura K, Kobayashi T, Zhang Z, Prasoon P, Hirose Y, Ishikawa H, Takizawa K, Sakata J, Miura S, Sasaoka T, Wakai T
  • Journal Title: Transplantation Proceedings Volume: 54 Pages: 507-512
  • DOI: 10.1016/j.transproceed.2021.10.029
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Facial temperature and pupil size as indicators of internal state in primates. (2022)
  • Author(s): Koji Kuraoka, Kae Nakamura
  • Journal Title: Neuroscience research Volume: 175 Pages: 25-37
  • DOI: 10.1016/j.neures.2022.01.002
  • Peer Reviewed
• [Journal Article] FBX047 is essential for preventing the synaptonemal complex from premature disassembly in mouse malemeiosis (2022)
  • Author(s): Tanno N, Takemoto K, Takada-Horisawa Y, Shimada R., Fujimura S, Tani N., Takeda N., Araki K, Ishiguro K
  • Journal Title: iScience
  • DOI: 10.1016/j.isci.2022.104008
  • Peer Reviewed / Open Access
• [Journal Article] Functional polymorphism in Pak1-3'UTR alters skin tumor susceptibility by alternative polyadenylation (2022)
  • Author(s): Kazuhiro Okumura, Megumi Saito, Eriko Isogai, Yurika Tokunaga, Yoshinori Hasegawa, Kimi Araki, Yuichi Wakabayashi
  • Journal Title: Journal of Investigative Dermatology
  • DOI: 10.1016/j.jid.2022.02.009
  • Peer Reviewed
• [Journal Article] Identification of a diarylpentanoid-producing polyketide synthase revealing an unusual biosynthetic pathway of 2-(2-phenylethy1)chromones in agarwood. (2022)
  • Author(s): Wang, X. -H., Abe, I., Morita, H., Tu, P. -F., Shi, S. -P., et al.
  • Journal Title: Nature Commun. Volume: 13 Pages: 348
  • DOI: 10.1038/s41467-022-27971-z
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Identification of a small molecule that enhances ferroptosis via inhibition of ferroptosis suppressor protein 1 (FSP1). (2022)
  • Author(s): Yoshioka H, Kawamura T, Muroi M, Kondoh Y, Honda K, Kawatani M, Aono H, Waldmann H, Watanabe N, Osada H.
  • Journal Title: ACS Chem Biol Volume: 17 Pages: 483-491
  • DOI: 10.1021/acschembio.2c00028
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Impact of GAD65 and/or GAD67 deficiency on perinatal development in rats (2022)
  • Author(s): Jiang W, Kakizaki T, Fujihara K, Miyata S, Zhang Y, Suto T, Saito S, Shibasaki K, Ishizaki Y, Yokoo H, Obinata H, Miyasaka Y, Mashimo T, Yanagawa Y., et al.
  • Journal Title: FASEB J Volume: 36 Pages: e22123
  • DOI: 10.1096/fj.202101389R
  • Peer Reviewed
• [Journal Article] Into the matrix : current methods for mitochondrial translation studies. (2022)
  • Author(s): Apostolopoulos A and Iwasaki S
  • Journal Title: J Biochem. Volume: 171 Pages: 379-387
  • DOI: 10.1093/jb/mvac005
  • Peer Reviewed / Open Access
• [Journal Article] Intracrine activity involving NAD-dependent circadian steroidogenic activity governs age-associated meibomian gland dysfunction (2022)
  • Author(s): Sasaki L*, Hamada Y*, Yarimizu D*, (20 people), Miyake T, Doi M# * : co-first, # : corresponding
  • Journal Title: Nature Aging Volume: 2 Pages: 105-114
  • DOI: 10.1038/s43587-021-00167-8
  • Peer Reviewed / Open Access
• [Journal Article] Isolation of new derivatives of the 20-membered macrodiolide bispolide from Kitasatospora sp. MG372-hF19 (2022)
  • Author(s): Kohda Y, Sakamoto S, Umekita M, Kimura T, Kubota Y, Arisaka R, Shibuya Y, Muramatsu H, Sawa R, Dan S, Kawada M, Igarashi M.
  • Journal Title: The Journal of Antibiotics Volume: 75 Pages: 77-85
  • DOI: 10.1038/s41429-021-00492-5
  • Peer Reviewed
• [Journal Article] JAM-A interacts with α3β1 integrin and tetraspanins CD151 and CD9 to regulate collective cell migration of polarized epithelial cells (2022)
  • Author(s): Sonja Thölmann, Jochen Seebach, Tetsuhisa Otani, Luise Florin, Hans Schnittler, Volker Gerke, Mikio Furuse, Klaus Ebnet
  • Journal Title: Cellular and Molecular Life Sciences Volume: 79 Pages: 1-19
  • DOI: 10.1007/s00018-022-04140-5
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] JNK1-dependent phosphorylation of GAP-43 Serine 142 is a novel molecular marker for axonal growth. (2022)
  • Author(s): Okada M, Kawagoe Y, Takasugi T, Nozumi M, Ito Y, Fukusumi H, Kanemura Y, Fujii Y, Igarashi M
  • Journal Title: Neurochem Res
  • DOI: 10.1007/s11064-022-03580-6
  • Peer Reviewed / Open Access
• [Journal Article] Mental construction of object symbols from meaningless elements by Japanese macaques (Macaca fuscata) (2022)
  • Author(s): Liu N, Iijima A, Iwata Y, Ohashi K, Fujisawa N, Sasaoka T, Hasegawa I.
  • Journal Title: Scientific Reports Volume: 12
  • DOI: 10.1038/s41598-022-07563-z
  • Peer Reviewed / Open Access
• [Journal Article] Molecular insights into the unusually promiscuous and catalytically versatile Fe(II)/α-ketoglutarate-dependent oxygenase SptF. (2022)
  • Author(s): Tao, H., # Mori, T., # Chen, H., Lyu, S., Nonoyama, A., Lee, S., Abe, I. (#equall contribution)
  • Journal Title: Nature Commun Volume: 13 Pages: 95
  • DOI: 10.1038/s41467-021-27636-3
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Nardilysin in adipocytes regulates UCP1 expression and body temperature homeostasis (2022)
  • Author(s): Sayaka Saijo, Mikiko Ohno, Hirotaka Iwasaki, Shintaro Matsuda, Kiyoto Nishi, Yoshinori Hiraoka, Natsuki Ide, Takeshi Kimura, Eiichiro Nishi
  • Journal Title: Scientific Reports Volume: 12 Pages: 3449
  • DOI: 10.1038/s41598-022-07379-x
  • Peer Reviewed / Open Access
• [Journal Article] Perturbation of monoamine metabolism and enhanced fear responses in mice defective in the regeneration of tetrahydrobiopterin. (2022)
  • Author(s): Miyajima K, Sudo Y, Sanechika S, Hara S, Inoue K, Takada M, Yoshioka N, Takebayashi H, Sugimoto M, Sumi-Ichinose C, Takao K, Miyakawa T, Ichinose H, et al.
  • Journal Title: Journal of Neurochemistry
  • DOI: 10.1111/jnc.15600
  • Peer Reviewed
• [Journal Article] Ribosome slowdown triggers codon-mediated mRNA decay independently of ribosome quality control. (2022)
  • Author(s): Mishima Y, Han P, Ishibashi K, Kimura S, and Iwasaki S
  • Journal Title: EMBO J. Volume: 41 Issue: 5 Pages: e109256
  • DOI: 10.15252/embj.2021109256
  • Peer Reviewed
• [Journal Article] Roles of the Circadian Clock Mechanism in the Regulation of Daily Rhythms of Body Temperature (2022)
  • Author(s): Miyake T, Doi M
  • Journal Title: Brain and nerve Volume: 74 Pages: 159-166
  • DOI: 10.11477/mf.1416202001
• [Journal Article] Selective translation of epigenetic modifiers affects the temporal pattern and differentiation of neural stem cells. (2022)
  • Author(s): Wu Q, Shichino Y, Abe T, Suetsugu T, Omori A, Kiyonari H, Iwasaki S, and Matsuzaki F
  • Journal Title: Nat Commun. Volume: 13 Issue: 1 Pages: 470
  • DOI: 10.1038/s41467-022-28097-y
  • Peer Reviewed / Open Access
• [Journal Article] Sexually dimorphic properties in meiotic chromosome (2022)
  • Author(s): Ishiguro K
  • Journal Title: Sexual Development
  • DOI: 10.1159/000520682
  • Peer Reviewed / Open Access
• [Journal Article] Splicing modulators elicit global translational repression by condensate-prone proteins translated from introns. (2022)
  • Author(s): Chhipi Shrestha JK, Schneider-Poetsch T, Suzuki T, Mito M, Khan K, Dohmae N, Iwasaki S, and Yoshida M
  • Journal Title: Cell Chem Biol. Volume: 29 Pages: 259-275
  • DOI: 10.1016/j.chembiol.2021.07.015
  • Peer Reviewed
• [Journal Article] The dual role of dopamine in the modulation of information processing in the prefrontal cortex underlying social behavior (2022)
  • Author(s): Hidekazu Sotoyama, Hiroyoshi Inaba, Yuriko Iwakura, Hisaaki Namba, Nobuyuki Takei, Toshikuni Sasaoka, Hiroyuki Nawa
  • Journal Title: The FASEB Journal Volume: 36 Pages: e22160
  • DOI: 10.1096/fj.202101637R
  • Peer Reviewed
• [Journal Article] The landscape of translational stall sites in bacteria revealed by monosome and disome profiling. (2022)
  • Author(s): Fujita T, Yokoyama T, Shirouzu M, Taguchi H, Ito T, and Iwasaki S
  • Journal Title: RNA Volume: 28 Issue: 3 Pages: 290-302
  • DOI: 10.1261/rna.078188.120
  • Peer Reviewed
• [Journal Article] The Mlc1 promotor directs Muller cell-specific gene expression in the retina. (2022)
  • Author(s): Danjo Y, Shinozaki Y, Natsubori A, Kubota Y, Kashiwagi K, Tanaka KF, Koizumi S.
  • Journal Title: translational vision science & technology Volume: 11 Pages: 25
  • DOI: 10.1167/tvst.11.1.25
  • Peer Reviewed / Open Access
• [Journal Article] Transcription factor MafB-mediated inhibition of type I interferons in plasmacytoid dendritic cells (2022)
  • Author(s): Hiroyuki Saiga, Masaki Ueno, Takashi Tanaka, Tsuneyasu Kaisho, Katsuaki Hoshino
  • Journal Title: International Immunology Volume: 34 Pages: 159-172
  • DOI: 10.1093/intimm/dxab103
  • Peer Reviewed
• [Journal Article] TT-pocket/HIRAN : binding to 3' -terminus of DNA for recognition and processing of stalled replication forks. (2022)
  • Author(s): Masai, H.
  • Journal Title: J. Biochem.
  • Peer Reviewed
• [Journal Article] Vestigial-like family member 3 (VGLL3) stimulates cell motility by inducing High mobility group AT-hook 2 (HMGA2) expression in cancer cells (2022)
  • Author(s): Naoto Hori, Yuki Takakura, Ayumi Sugino, Shuto Iwasawa, Kota Nomizo, Naoto Yamaguchi, Hiroyuki Takano, Noritaka Yamaguchi
  • Journal Title: Journal of Cellular and Molecular Medicine
  • DOI: 10.1111/jcmm.17279
  • Peer Reviewed / Open Access
• [Journal Article] D1 receptor mediated dopaminergic neurotransmission facilitates remote memory of contextual fear conditioning. (2022)
  • Author(s): Nae Saito, Makoto Itakura, Toshikuni Sasaoka*
  • Journal Title: Frontiers in Behavioral Neuroscience Volume: 16 Pages: 751053
  • DOI: 10.3389/fnbeh.2022.751053
  • Peer Reviewed / Open Access
• [Journal Article] A Flp-dependent G-CaMP9a transgenic mouse for neuronal imaging in vivo. (2022)
  • Author(s): Sakamoto M, Inoue M, Takeuchi A, Kobari S, Yokoyama T, Horigane S, Takemoto-Kimura S, Abe M, Sakimura K, Kano M, Kitamura K, Fujii H, Bito H.
  • Journal Title: Cell Reports Methods Volume: 2 Pages: 100168
  • DOI: 10.1016/j.crmeth.2022.100168
  • Peer Reviewed / Open Access
• [Journal Article] Immunomodulation by Inflammation during Liver and Gastrointestinal Tumorigenesis and Aging. (2021)
  • Author(s): Nagai N, Kudo Y, Aki D, Nakagawa H, Taniguchi K.
  • Journal Title: Int J Mol Sci. Volume: 22 Pages: 2238
  • DOI: 10.3390/ijms22052238
  • Peer Reviewed / Open Access
• [Journal Article] Nascent polypeptide within the exit tunnel stabilizes the ribosome to counteract risky translation. (2021)
  • Author(s): Chadani Y, Sugata N, Niwa T, Ito Y, Iwasaki S, and Taguchi H
  • Journal Title: EMBO J. Volume: 40 Issue: 23 Pages: e108299
  • DOI: 10.15252/embj.2021108299
  • Peer Reviewed
• [Journal Article] Vasopressin escape and memory impairment in a model of chronic syndrome of inappropriate secretion of antidiuretic hormone in mice. (2021)
  • Author(s): Kawakami T, Fujisawa H, Nakayama S, Yoshino Y, Hattori S, Seino Y, Takayanagi T, Miyakawa T, Suzuki A, Sugimura Y.
  • Journal Title: Endocrine Journal Volume: 68 Pages: 31-43
  • DOI: 10.1507/endocrj.EJ20-0289
  • Peer Reviewed / Open Access
• [Journal Article] 上皮管腔形態形成の分子機構とその異常による腫瘍形成 (2021)
  • Author(s): 松本真司
  • Journal Title: Journal of Japanese Biochemical Society Volume: 93 Pages: 733-748
  • DOI: 10.14952/SEIKAGAKU.2021.930733
  • Peer Reviewed
• [Journal Article] 【意思決定と行動選択の神経科学】セロトニンと意思決定 (2021)
  • Author(s): 中村 加枝, 石井 宏憲, 安田 正治
  • Journal Title: Clinical Neuroscience Volume: 39 Issue: 8 Pages: 979-983
• [Journal Article] A description of novel variants and review of phenotypic spectrum in UBA5-related early epileptic encephalopathy (2021)
  • Author(s): Lauren C Briere, Melissa A Walker, Frances A High, Cynthia Cooper, ......, Masaaki Komatsu (19人中18番目), David A Sweetser
  • Journal Title: Cold Spring Harb Mol Case Stud Volume: 7 Pages: a005827
  • DOI: 10.1101/mcs.a005827
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A novel oral inhibitor for one-carbon metabolism and checkpoint kinase 1 inhibitor as a rational combination treatment for breast cancer (2021)
  • Author(s): Jin Lee, Xiaoxi Chen, Yuming Wang, Tatsunori Nishimura, Mengjiao Li, Satoko Ishikawa, Takiko Daikoku, Junya Kawai, Arinobu Tojo, Noriko Gotoh
  • Journal Title: Biochem Biophys Res Commun Volume: 584 Pages: 7-14
  • DOI: 10.1016/j.bbrc.2021.11.001
  • Peer Reviewed / Open Access
• [Journal Article] A role of BDNF in the depression pathogenesis and a potential target as antidepressant : the modulator of stress sensitivity "Shati/Nat81-BDNF system" in the dorsal striatum (2021)
  • Author(s): Miyanishi H, Nitta A
  • Journal Title: Pharmaceuticals Volume: 14 Pages: 889
  • DOI: 10.3390/ph14090889
  • Peer Reviewed / Open Access
• [Journal Article] A subset of cone bipolar cells expresses the Na(+) channel SCN2A in the human retina. (2021)
  • Author(s): Kawai, F., Ohkuma, M., Horiguchi, M., Ichinose, H., and Miyachi, E. I.
  • Journal Title: Exp. Eye Res. Volume: 202 Pages: 108299
  • DOI: 10.1016/j.exer.2020.108299
  • Peer Reviewed
• [Journal Article] A wild-derived inbred mouse strain, MSM/Ms, provides insights into novel skin tumor susceptibility genes (2021)
  • Author(s): Kazuhiro Okumura(責任著者), Megumi Saito, Yuichi Wakabayashi
  • Journal Title: Experimental Animals Volume: 70 Issue: 3 Pages: 272-283
  • DOI: 10.1538/expanim.21-0017
  • Peer Reviewed / Open Access
• [Journal Article] Active transition of fear memory phase from reconsolidation to extinction through ERK-mediated prevention of reconsolidation. (2021)
  • Author(s): Fukushima, H., Zhang, Y., Kida, S.*
  • Journal Title: J. Neurosci. Volume: 41 Pages: 1288-1300
  • DOI: 10.1523/JNEUROSCI.1854-20.2020
  • Peer Reviewed
• [Journal Article] Adenosine A2B receptor down-regulates metabotropic glutamate receptor 5 in astrocytes during postnatal development (2021)
  • Author(s): Tanaka, M., Shigetomi, E., Parajuli, B., Nagatomo, H., Lee, JH., Kim, SK., Nabekura, J., Koizumi, S., et al.
  • Journal Title: GLIA Volume: 69 Pages: 2546-2558
  • DOI: 10.1002/glia.24006
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Adipsin-Dependent Secretion of Hepatocyte Growth Factor Regulates the Adipocyte-Cancer Stem Cell Interaction. (2021)
  • Author(s): Mizuno M, Khaledian B, Maeda M, Hayashi T, Mizuno S, Kono S, Okada S, Suzuki M, Takao S, Minami H, Asai N, Sugiyama F, Takahashi S, Shimono Y, et al.
  • Journal Title: Cancers Volume: 13 Pages: e4238
  • DOI: 10.3390/cancers13164238
  • Peer Reviewed / Open Access
• [Journal Article] Adoptive cell therapy using tumor-infiltrating lymphocytes for melanoma refractory to immune-checkpoint inhibitors (2021)
  • Author(s): Hirai I, Funakoshi T, Kami juku H., Ohta S, Fujita T, Tanosaki R, Handa M, Okamoto S, Amagai M, Kawakami Y.
  • Journal Title: Cancer Sci Volume: 112 Pages: 3163-3172
  • DOI: 10.1111/cas.15009
  • Peer Reviewed
• [Journal Article] ALKBH4 promotes tumourigenesis with a poor prognosis in non-small-cell lung cancer. (2021)
  • Author(s): Jingushi K, Aoki M, Kawahara K, Furukawa T, Tsujikawa K, et al.
  • Journal Title: Sci Rep Volume: 11 Pages: 8677-8677
  • DOI: 10.1038/s41598-021-87763-1
  • Peer Reviewed / Open Access
• [Journal Article] An engineered channelrhodopsin optimized for axon terminal activation and circuit mapping. (2021)
  • Author(s): Shun Hamada, Masashi Nagase, Tomohiko Yoshizawa, Akari Hagiwara, Yoshikazu Isomura, Ayako M Watabe, Toshihisa Ohtsuka.
  • Journal Title: Communications Biology Volume: 4 Pages: 461
  • DOI: 10.1038/s42003-021-01977-7
  • Peer Reviewed / Open Access
• [Journal Article] Angulin-1 seals tricellular contacts independently of tricellulin and claudins (2021)
  • Author(s): Taichi Sugawara, Kyoko Furuse, Tetsuhisa Otani, Tomohiko Wakayama, Mikio Furuse
  • Journal Title: Journal of Cell Biology Volume: 220 Pages: e202005062
  • DOI: 10.1083/jcb.202005062
  • Peer Reviewed
• [Journal Article] Anti-TLR7 Antibody Protects Against Lupus Nephritis in NZBWF1 Mice by Targeting B Cells and Patrolling Monocytes (2021)
  • Author(s): Yusuke Murakami, Ryutaro Fukui, Reika Tanaka, Yuji Motoi, Atsuo Kanno, Ryota Sato, Kiyoshi Yamaguchi, Yoichi Furukawa, Naomi Yamashita, Kensuke Miyake
  • Journal Title: Frontiers in Immunology Volume: 12 Pages: 777197
  • DOI: 10.3389/fimmu.2021.777197.eCollection2021
  • Peer Reviewed / Open Access
• [Journal Article] ArcRNAs and the formation of nuclear bodies (2021)
  • Author(s): Shinichi Nakagawa, Tomohiro Yamazaki, Taro Mannen, Tetsuro Hirose
  • Journal Title: Mammalian Genomes
  • DOI: 10.1007/s00335-021-09881-5
  • Peer Reviewed
• [Journal Article] Aziridine formation by a Fe(II)/α-ketoglutarate dependent oxygenase and 2-aminoisobutyrate biosynthesis in fungi (2021)
  • Author(s): Bunno, T., Awakawa, T., Mori, T., Abe, I.
  • Journal Title: Angew. Chem. Int. Ed. Volume: 60 Pages: 15827-15831
  • DOI: 10.1002/anie.202104644
  • Peer Reviewed
• [Journal Article] BHLHE41/DEC2 Expression Induces Autophagic Cell Death in Lung Cancer Cells and Is Associated with Favorable Prognosis for Patients with Lung Adenocarcinoma (2021)
  • Author(s): Toshiyuki Nagata, Kentaro Minami, Masatatsu Yamamoto, Tsubasa Hiraki, ...... Masaaki Komatsu (16人中13番目), Akihide Tanimoto, Tatsuhiko Furukawa and Masami Sato
  • Journal Title: Int. J. Mol. Sci. Volume: 22 Pages: 11509
  • DOI: 10.3390/ijms222111509
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Brain-specific heterozygous loss-of-function of ATP2A2, endoplasmic reticulum Ca2+ pump responsible for Darier's disease, causes behavioral abnormalities and a hyper-dopaminergic state (2021)
  • Author(s): Nakajima K, Ishiwata M, Weitemier AZ, Shoji H, Monai H, Miyamoto H, Yamakawa K, Miyakawa T, McHugh TJ, Kato T
  • Journal Title: Human Molecular Genetics Volume: 30 Pages: 1762-1772
  • DOI: 10.1093/hmg/ddab137
  • Peer Reviewed / Open Access
• [Journal Article] Cardio- and reno-protective effects of dipeptidyl peptidase III in diabetic mice. (2021)
  • Author(s): Komeno M, Pang X, Shimizu A, ..., Ogita H.
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• [Journal Article] Cell-to-cell contact-mediated regulation of tumor behavior in the tumor microenvironment. (2021)
  • Author(s): Sato A, Rahman NIA, Shimizu A, Ogita H.
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  • Peer Reviewed / Open Access
• [Journal Article] C-Glycoside metabolism in the gut and in nature : Identification, characterization, structural analyses and distribution of C-C bond-cleaving enzymes (2021)
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  • Journal Title: Biomolecules Volume: 11 Pages: 1853
  • DOI: 10.3390/biom11121853
  • Peer Reviewed / Open Access
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• [Journal Article] Chemical Genetics Reveals a Role of Squalene Synthase in TGFβ Signaling and Cardiomyogenesis (2021)
  • Author(s): Yasushi Takemoto, Shin Kadota, Itsunari Minami, Shinya Otsuka, Satoshi Okuda, Masahiro Abo, Louvy Lynn Punzalan, Yan Shen, Yuji Shiba, Motonari Uesugi
  • Journal Title: Angewandte Chemie International Edition Volume: 60 Pages: 21824-21831
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  • Peer Reviewed
• [Journal Article] Chemical targeting of G-quadruplexes in telomeres and beyond for molecular cancer therapeutics (2021)
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  • Peer Reviewed
• [Journal Article] Chondroitin sulfate N-acetylgalactosaminyltransferase-2 plays a cardioprotective role in heart failure caused by acute pressure overload. (2021)
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  • Peer Reviewed
• [Journal Article] Congenital Hypothyroidism and Brain Development : Association with Other Psychiatric Disorders (2021)
  • Author(s): Katsuya Uchida and Mao Suzuki
  • Journal Title: Frontiers in Neuroscience Volume: 15 Pages: 772382
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  • Peer Reviewed / Open Access
• [Journal Article] Coordination of retrotransposons and type I interferon with distinct interferon pathways in dermatomyositis, systemic lupus erythematosus and autoimmune blistering disease (2021)
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• [Journal Article] Crosstalk Between NDP52 and LUBAC in Innate Immune Responses, Cell Death, and Xenophagy (2021)
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• [Journal Article] Ddx20, DEAD box helicase 20, is essential for the differentiation of oligodendrocyte and maintenance of myelin gene expression. (2021)
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  • Journal Title: Glia Volume: 69 Pages: 2559-2574
  • DOI: 10.1002/glia.24058
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• [Journal Article] DEAD-box polypeptide 43 facilitates piRNA amplification by actively liberating RNA from Ago3-piRISC (2021)
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• [Journal Article] Descending and ascending signals that maintain rhythmic walking pattern in the cricket (2021)
  • Author(s): Naniwa, K. and Aonuma H.
  • Journal Title: Frontiers in Robotics and AI Volume: 8 Pages: 625094
  • DOI: 10.3389/frobt.2021.625094
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• [Journal Article] Development of a DELFIA method to detect oncofetal antigen ROR1-positive exosomes. (2021)
  • Author(s): Daikuzono H, Yamazaki M, Sato Y, Takahashi T, Yamagata K
  • Journal Title: Biochem Biophys Res Commun. Volume: 578 Pages: 170-176
  • DOI: 10.1016/j.bbrc.2021.08.054
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• [Journal Article] Development of a highly sensitive method for the quantitative analysis of modified nucleosides using UHPLC-UniSpray-MS/MS. (2021)
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• [Journal Article] Development of an optogenetic gene sensitive to daylight and its implications in vision restoration (2021)
  • Author(s): Watanabe Y, Sugano E, Tabata K, Hatakeyama A, Sakajiri T, Fukuda T, Ozaki T, Suzuki T, Sayama T, Tomita H
  • Journal Title: npj Regenerative Medicine Volume: 6 Issue: 1 Pages: 64
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  • Peer Reviewed
• [Journal Article] Dietary magnesium deficiency induces the expression of neuroinflammation-related genes in mouse brain. (2021)
  • Author(s): Tsuji, R., Inoue, H., Uehara, M., Kida, S.*
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• [Journal Article] Discovery of AS-0141, a Potent and Selective Inhibitor of CDC7 Kinase for the Treatment of Solid Cancers. (2021)
  • Author(s): Irie, T., Asami, T., Sawa, A., Uno, Y., Taniyama, C., Funakoshi, Y., Masai, H., Sawa, M.
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• [Journal Article] Divergent synthesis of functionalized dihydropyridines and pyrroles via metal-free one-pot domino reactions of a gem-disubstituted propargyl amine and an alkynyl sulfone (2021)
  • Author(s): Yuta Arai, Hiroki Oguri*
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• [Journal Article] Double-edged Sword Role of Iron-loaded Ferritin in Extracellular Vesicles. (2021)
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  • Journal Title: J Cancer Prev 26 : 244-249, 2021 Volume: 26 Pages: 244-249
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• [Journal Article] Early postnatal inhibition of GLAST causes abnormalities of psychobehaviors and neuronal morphology in adult mice. (2021)
  • Author(s): Uchida M, Noda Y, Hasegawa S, Hida H, Taniguchi M, Mouri A, Yoshimi A, Nabeshima T, Yamada K, Aida T, Tanaka K, Ozaki N.
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  • DOI: 10.1016/j.neuint.2021.105177
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• [Journal Article] eIF2B-capturing viral protein NSs suppresses the integrated stress response. (2021)
  • Author(s): Kashiwagi K, Shichino Y, Osaki T, Sakamoto A, Nishimoto M, Takahashi M, Mito M, Weber F, Ikeuchi Y, Iwasaki S, and Ito T
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• [Journal Article] Epinephrine Production in Th17 Cells and Experimental Autoimmune Encephalitis. (2021)
  • Author(s): Yang, P., Tian, H., Zou, Y. R., Chambon, P., Ichinose, H., Honig, G., Diamond, B., and Kim, S. J.
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• [Journal Article] Epithelial cell transformation and senescence as indicators of genome aging : current advances and unanswered questions. (2021)
  • Author(s): Kitakaze, M., Chijimatsu, R., Vecchione, A., Kitagawa, T., Doki, Y., Eguchi, H., Ishii, H.
  • Journal Title: Int. J. Mol. Sci. Volume: 22 Pages: 7544
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  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Essential role of autophagy in protecting neonatal haematopoietic stem cells from oxidative stress in a p62-independent manner (2021)
  • Author(s): Naho Nomura, Chiaki Ito, Takako Ooshiol, ..., Masaaki Komatsu (15人中13番目), Toruyanagawa, Atsushi Hirao
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  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Evaluation of the in vitro cytotoxicity of oscillatoxins E and F under nutrient-starvation culture conditions (2021)
  • Author(s): Yusuke Hanaki, Yusuke Araki, Toshio Nishikawa, Ryo C. Yanagita
  • Journal Title: Fundamental Toxicological Sciences Volume: 8 Issue: 3 Pages: 69-73
  • DOI: 10.2131/fts.8.69
  • Peer Reviewed
• [Journal Article] Extremely low-frequency electromagnetic fields entrain locust wingbeats (2021)
  • Author(s): Shepherd S., Jackson C.W., Sharkh S.M., Aonuma H., Oliveira E.E. and Newland P.L.
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• [Journal Article] Eye gaze differences in school scenes between preschool children and adolescents with high-functioning autism spectrum disorder and those with typical development. (2021)
  • Author(s): Ishizaki Y., Higuchi T., Yanagimoto Y., Kobayashi H., Noritake A., Nakamura K., Kaneko K.
  • Journal Title: BioPsychoSocial medicine Volume: 15 Issue: 1 Pages: 2-2
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  • Peer Reviewed / Open Access
• [Journal Article] Fisl ablation in the male germline disrupts mitochondrial morphology and mitophagy, and arrests spermatid maturation (2021)
  • Author(s): Grigor Varuzhanyan, Mark S Ladinsky, Shun-Ichi Yamashita, Manabu Abe, Kenji Sakimura, Tomotake Kanki, David C Chan
  • Journal Title: Development Volume: 148 Pages: dev199686
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  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] GABAergic neuron-specific whole-brain transduction by AAV-PHP.B incorporated with a new GAD65 promoter (2021)
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• [Journal Article] Gata3 is essential for separating patterning domains during facial morphogenesis. (2021)
  • Author(s): Abe M., Cox T. C., Firulli A. B., Kanai S. M., Dalhka J., Lim K-C., Engel D. J., Clouthier D. E.
  • Journal Title: Development
  • DOI: 10.1242/dev.199534
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Gene trapping reveals a new transcriptionally active genome element : The chromosome - specific clustered trap region. (2021)
  • Author(s): Takeda, I., Araki, M., Ishiguro, K., Ohga, T., Takada, K., Yamaguchi, Y., Hashimoto, K., Kai, T., Nakagata, N., Imasaka, M., Yoshinobu, K. and Araki, K.
  • Journal Title: Genes to Cells Volume: 26 Pages: 874-890
  • DOI: 10.1111/gtc.12890
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• [Journal Article] Genetic polymorphisms of lysophosphatidic acid receptor 1 are associated with the onset of taxane-induced peripheral neuropathy (2021)
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  • Journal Title: British Journal of Anaesthesia Volume: 127 Pages: 43-46
  • DOI: 10.1016/j.bja.2021.04.014
  • Peer Reviewed
• [Journal Article] Gpr19 is a circadian clock-controlled orphan GPCR with a role in modulating free-running period and light resetting capacity of the circadian clock (2021)
  • Author(s): Yoshiaki Yamaguchi, Iori Murai, Kaoru Goto, Shotaro Doi, Huihua Zhou, Genzui Setsu, Hiroyuki Shimatani, Hitoshi Okamura, Takahito Miyake, Masao Doi
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  • Peer Reviewed / Open Access
• [Journal Article] Hamster PIWI proteins bind to piRNAs with stage-specific size variations during oocyte maturation (2021)
  • Author(s): Ishino K(第一著者), Hasuwa H, Yoshimura J, Iwasaki YW, Nishihara H, Seki NM, Hirano T, Tsuchiya M, Ishizaki H, Siomi MC(研究代表者), Morishita S, Siomi H(責任著者)
  • Journal Title: Nucl. Acid. Res. Volume: 49 Pages: 2700-2720
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• [Journal Article] Heat-sterilized Bifidobacterium breve prevents depression-like behavior and interleukin-1β expression in mice exposed to chronic social defeat stress. (2021)
  • Author(s): Kosuge A, Kunisawa K, Arai S, Sugawara Y, Shinohara K, Iida T, Wulaer B, Kawai T, Fujigaki H, Yamamoto Y, Saito K, Nabeshima T, Mouri A.
  • Journal Title: Brain Behav Immun. Volume: 96 Pages: 200-211
  • DOI: 10.1016/j.bbi.2021.05.028
  • Peer Reviewed
• [Journal Article] Heterodimeric Non-heme Iron Enzymes in Fungal Meroterpenoid Biosynthesis. (2021)
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  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Hexa Histidine-Tagged Recombinant Human Cytoglobin Deactivates Hepatic Stellate Cells and Inhibits Liver Fibrosis by Scavenging Reactive Oxygen Species (2021)
  • Author(s): Dat NQ, 略15名, Tokunaga F, Pinzani M, Kawada N.
  • Journal Title: Hepatology Volume: 73 Pages: 2527-2545
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  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Hypothermia cannot ameliorate renal fibrosis after asphyxia in the newborn piglet (2021)
  • Author(s): Wakabayashi, T., Nakamura, S., Nakao, Y., Yamato, S., Htun, Y., Mitsuie, T., Morimoto, A., Arioka, M., Koyano, K., Konishi, Y., Miki, T., Ueno, M., Kusaka, T.
  • Journal Title: Pediatric International
  • DOI: 10.1111/ped.14961
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• [Journal Article] Identification of a small-molecule glucose transporter inhibitor, glutipyran, that inhibits cancer cell growth. (2021)
  • Author(s): Kawatani M, Aono H, Hiranuma S, Shimizu T, Muroi M, Ogawa N, Ohishi T, Ohba SI, Kawada M, Nogawa T, Okano A, Hashizume D, Osada H.
  • Journal Title: ACS Chem Biol Volume: 16 Pages: 1576-1586
  • DOI: 10.1021/acschembio.1c00480
  • Peer Reviewed
• [Journal Article] Identification of dihydroorotate dehydrogenase inhibitors-indoluidins-that inhibit cancer cell growth. (2021)
  • Author(s): Kawatani M., Aono H., Shimizu T., Ohkura S., Hiranuma S., Muroi M., Ogawa N., Ohishi T., Ohba S., Kawada M., Yamazaki K., Dan S., Osada H.
  • Journal Title: ACS Chem. Biol. Volume: 16 Pages: 2570-2580
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  • Peer Reviewed
• [Journal Article] Imaging Voltage with Microbial Rhodopsins (2021)
  • Author(s): Xiao Min Zhang, Tatsushi Yokoyama, Masayuki Sakamoto
  • Journal Title: Frontiers in Molecular Biosciences Volume: 8
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  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Immortalization of cells derived from domestic dogs through expressing mutant cyclin-dependent kinase 4, cyclin D1, and telomerase reverse transcriptase (2021)
  • Author(s): Munirah I, Ozaki T, Sekine A, Morimoto M, Sugawara M, Takada H, Sugano E, Tomita H, Kiyono T, Fukuda T
  • Journal Title: Cytotechnology
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• [Journal Article] Impact of one-carbon metabolism-driving epitranscriptome as a therapeutic target for gastrointestinal cancer. (2021)
  • Author(s): Takeda, Y., Chijimatsu, R., Vecchione, A., Arai, T., Kitagawa, T., Ofusa, K., Yabumoto, M., Hirotsu, T., Eguchi, H., Doki, Y., Ishii, H.
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• [Journal Article] Impaired wakefulness and rapid eye movement sleep in dopamine-deficient mice (2021)
  • Author(s): Mitsuaki Kashiwagi, Mika Kanuka, Kaeko Tanaka, Masayo Fujita, Ayaka Nakai, Chika Tatsuzawa, Kazuto Kobayashi, Kazutaka Ikeda & Yu Hayashi
  • Journal Title: Molecular Brain Volume: 14 Pages: 170
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• [Journal Article] Importance of the Q/N-rich segment for protein stability and activity of endogenous mouse TDP-43. (2021)
  • Author(s): Sato T*, Oda K, Sakai S, Kato R, Yamamori S, Itakura M, Kodera Y, Nishizawa M, Sasaoka T, Onodera O, Yokoyama M
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• [Journal Article] Improvement of short straws for sperm cryopreservation : installing an air-permeable filter facilitates handling (2021)
  • Author(s): Kaneko R, Kakinuma T, Sato S, Jinno-Oue A.
  • Journal Title: J Reprod Dev. Volume: 67 Pages: 235-239
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• [Journal Article] Inflammation-Induced Tumorigenesis and Metastasis. (2021)
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• [Journal Article] Inhibition of vascular adhesion protein-1 enhances the anti-tumor effects of immune checkpoint inhibitors (2021)
  • Author(s): Kinoshita T, Sayem MA, Yaguchi T, Kharma B, Morii K, Kato D, Ohta S, Mashima Y, Asamura H, Kawakami Y.
  • Journal Title: Cancer sci Volume: 112 Pages: 1390-1401
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• [Journal Article] Interactions between the amygdala and medial prefrontal cortex as upstream regulators of the hippocampus to reconsolidate and enhance retrieved inhibitory avoidance memory. (2021)
  • Author(s): Fukushima, H., Zhang, Y., Kida, S.*
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• [Journal Article] Interplay between protein acetylation and ubiquitination controls MCL1 protein stability (2021)
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  • Journal Title: Cell Rep. Volume: 37 Pages: 109988
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  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Interstitial axon collaterals of callosal neurons form association projections from the primary somatosensory to motor cortex in mice. (2021)
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  • Journal Title: Cereb. Cortex
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• [Journal Article] Intracellular density is a novel indicator of different stages of murine osteoblast lineage cells. (2021)
  • Author(s): Itoh Y., Itoh S., Naruse H., Kagioka T., Abe M., Hayashi M.
  • Journal Title: Journal of Cellular Biochemistry
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• [Journal Article] Involvement of PKCβI-SERT activity in stress vulnerability of mice exposed to twice-swim stress. (2021)
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• [Journal Article] Kynurenine 3-monooxygenase deficiency induces depression-like behavior via enhanced antagonism of α7 nicotinic acetylcholine receptors by kynurenic acid. (2021)
  • Author(s): Mori Y, Mouri A, Kunisawa K, Hirakawa M, Kubota H, Kosuge A, Niijima M, Hasegawa M, Kurahashi H, Murakami R, Hoshi M, Nakano T, Nabeshima T, Saito K.
  • Journal Title: Behav Brain Res Volume: 405 Pages: 113191
  • DOI: 10.1016/j.bbr.2021.113191
  • Peer Reviewed
• [Journal Article] Leg amputation modifies coordinated activation ofthe middle leg muscles in the cricket Gryllus bimaculatus (2021)
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• [Journal Article] LincRNA-p21 exon 1 expression correlates with Cdknla expression in vivo. (2021)
  • Author(s): Riki Furuhata, R., Imasaka, M., Sugimoto, M., Yoshinobu, K., Araki, M. and Araki, K.
  • Journal Title: Genes to Cells Volume: 27 Pages: 14-24
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• [Journal Article] Lisl mutation prevents basal radial glia-like cell production in the mouse. (2021)
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• [Journal Article] Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion (2021)
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• [Journal Article] Loss of full-length Rifl protein in 2-cell embryos is associated with zygotic transcriptional activation. (2021)
  • Author(s): Yoshizawa-Sugata, Y., Yamazaki, S., Mita-Yoshida, K., Ono, T., Nishito, Y., and *Masai, H.
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• [Journal Article] Loss of P2Y1 receptor triggers glaucoma-like pathology in mice. (2021)
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• [Journal Article] LOTUS, an endogenous Nogo receptor antagonist, is involved in synapse and memory formation. (2021)
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  • Peer Reviewed / Open Access
• [Journal Article] Manganese Dynamics in Mouse Brain After Systemic MnC12 Administration for Activation-Induced Manganese-Enhanced MRI (2021)
  • Author(s): Tanihira H, Fujiwara T, Kikuta S, Homma N and Osanai M
  • Journal Title: Frontiers in Neural Circuits Volume: 15 Pages: 787692
  • DOI: 10.3389/fncir.2021.787692
  • Peer Reviewed / Open Access
• [Journal Article] MEIOSIN directs initiation of meiosis and subsequent meiotic prophase programs during spermatogenesis (2021)
  • Author(s): Ishiguro K, Shimada R.
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  • Peer Reviewed / Open Access
• [Journal Article] Meiosis-specific ZFP541 repressor complex promotes developmental progression of meiotic prophase towards completion during mouse spermatogenesis (2021)
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  • Peer Reviewed / Open Access / Int'l Joint Research
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• [Journal Article] MicroRNA-142 Critically Regulates Group 2 Innate Lymphoid Cell Homeostasis and Function. (2021)
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  • Journal Title: Commun. Biol. Volume: 19 Pages: 80
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• [Journal Article] Mitochondrial complex I inhibitors suppress tumor growth through concomitant acidification of the intra-and extracellular environment. (2021)
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  • Journal Title: iScience Volume: 24 Pages: 103497
  • DOI: 10.1016/j.isci.2021.103497
  • Peer Reviewed / Open Access
• [Journal Article] Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes. (2021)
  • Author(s): Nishida M, Yamashita N, Ogawa T, Koseki K, Warabi E, Ohue T, Komatsu M, Matsushita H, Kakimi K, Kawakami E, Shiroguchi K, Udono H
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• [Journal Article] Molecular insights into the endoperoxide formation by Fe(II)/α-KG-dependent oxygenase NvfI (2021)
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  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Multiple nicotinic acetylcholine receptor subtypes regulate social or cognitive behaviors in mice repeatedly administered phencyclidine. (2021)
  • Author(s): Noda Y, Soeda K, Uchida M, Goto S, Ito T, Kitagaki S, Mamiya T, Yoshimi A, Ozaki N, Mouri A.
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  • DOI: 10.1016/j.bbr.2021.113284
  • Peer Reviewed
• [Journal Article] Mutual selfish manipulation enhances mutualism in an aphid-ant symbiosis (2021)
  • Author(s): Kudo T., Aonuma H. and Hasegawa E.
  • Journal Title: Scientific Reports Volume: 11 Pages: 18569
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• [Journal Article] Mutually repulsive EphA7-EfnA5 organize region-to-region corticopontine projection by inhibiting collateral extension. (2021)
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  • Journal Title: J. Neurosci Volume: 41 Issue: 22 Pages: 4795-4808
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  • Peer Reviewed
• [Journal Article] Neurexins in serotonergic neurons regulate serotonin release and complex mouse behaviors (2021)
  • Author(s): Amy Cheung. Aya Matsui, Manabu Abe, Kenji Sakimura, Toshikuni Sasaoka, Takeshi Uemura, Yuka Imamura Kawasawa and Kensuke Futai
  • Journal Title: bioRxiv
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  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Neuronal activity in the monkey prefrontal cortex during a duration discrimination task with visual and auditory cues (2021)
  • Author(s): Atsushi Chiba, Kazunori Morita, Ken-ichi Oshio, Masahiko Inase
  • Journal Title: Scientific Reports Volume: 11 Pages: 17520
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  • Peer Reviewed / Open Access
• [Journal Article] Neutralization of the induced VEGF-A potentiates the therapeutic effect of an anti-VEGFR2 antibody on gastric cancer in vivo (2021)
  • Author(s): Mashima T, Wakatsuki T, Kawata N, Jang MK, Nagamori A, Yoshida H, Nakamura K, Migita T, Seimiya H, Yamaguchi K
  • Journal Title: Sci Rep Volume: 11 Pages: 15125
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• [Journal Article] New Insights regarding diagnosis and medication for schizophrenia based on neuronal synapse-microglia interaction (2021)
  • Author(s): Izuo N, Nitta A
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  • Peer Reviewed / Open Access
• [Journal Article] Nicotine enhances firing activity of layer 5 pyramidal neurons in the medial prefrontal cortex through inhibition of Kv7 channels. (2021)
  • Author(s): Izumi S, Domoto M, Esaki H, Sasase H, Nishitani N, Deyama S, Kaneda K
  • Journal Title: Biological and Pharmaceutical Bulletin Volume: 44 Pages: 724-731
  • DOI: 10.1248/bpb.b21-00137
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• [Journal Article] Nicotine enhances object recognition memory through inhibition of voltage-dependent potassium 7 channels in the medial prefrontal cortex of mice. (2021)
  • Author(s): Esaki H, Izumi S, Fukao A, Nishitani N, Deyama S, Kaneda K
  • Journal Title: Journal of Pharmacological Sciences Volume: 147 Pages: 58-61
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• [Journal Article] Nicotine enhances object recognition memory via stimulating α4β2 and α7 nicotinic acetylcholine receptors in the medial prefrontal cortex of mice. (2021)
  • Author(s): Esaki H, Izumi S, Fukao A, Ito S, Nishitani N, Deyama S, Kaneda K
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• [Journal Article] One polyketide synthase, two distinct products : trans-acting enzyme-controlled product divergence in calbistrin biosynthesis (2021)
  • Author(s): Tao, H., Mori, T., Wei, X., Matsuda, Y., Abe, I.
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  • Author(s): Yusuke Hanaki, Yusuke Araki, Toshio Nishikawa, Ryo C. Yanagita
  • Journal Title: Heterocycles Volume: 102 Pages: 2353-2362
  • DOI: 10.3987/COM-21-14538
  • Peer Reviewed
• [Journal Article] p62/SQSTM1 droplets initiate autophagosome biogenesis and oxidative stress control (2021)
  • Author(s): Eskelinen EL, Kageyama S, Komatsu M
  • Journal Title: Mol Cell Oncol Volume: 8 Pages: 1890990
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  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response (2021)
  • Author(s): Shun Kageyama, Sigurdur Runar Gudmundsson, ... Satoshi Waguri, Eeva-Liisa Eskelinen, Masaaki Komatsu
  • Journal Title: Nature Communications Volume: 12 Pages: 1-16
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  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Pericentromeric noncoding RNA changes DNA binding of CTCF and inflammatory gene expression in senescence and cancer (2021)
  • Author(s): Miyata K, Imai Y, Hori S, Toyokuni S, Sakata T, Shirahige K, Kojima R, Nakayama M, Oshima M, Nagayama S, Seimiya H, Hirota T, Saya H, Hara E, Takahashi A, et al.
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• [Journal Article] Pharmacological blockade of dopamine D1- or D2-receptor in the prefrontal cortex induces attentional impairment in the object-based attention test through different neuronal circuits in mice. (2021)
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  • Journal Title: Mol Brain. Volume: 14 Pages: 43
  • DOI: 10.1186/s13041-021-00760-3
  • Peer Reviewed
• [Journal Article] PHLDA3 Is an Important Downstream Mediator of p53 in Squamous Cell Carcinogenesis (2021)
  • Author(s): Megumi Saito, Akane Sada, Masaki Fukuyo, Kiyono Aoki, Kazuhiro Okumura, Yuko Tabata, Yu Chen, Atsushi Kaneda, Yuichi Wakabayashi, Rieko Ohki
  • Journal Title: Journal of Investigative Dermatology Volume: S0022-202X Issue: 21 Pages: 02271-5
  • DOI: 10.1016/j.jid.2021.09.007
  • Peer Reviewed
• [Journal Article] Phototoxicities Caused by Continuous Light Exposure Were Not Induced in Retinal Ganglion Cells Transduced by an Optogenetic Gene (2021)
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• [Journal Article] PI4P/PS countertransport by ORP10 at ER-endosome membrane contact sites regulates endosome fission. (2021)
  • Author(s): Kawasaki A, Sakai A, Nakanishi H, Hasegawa J, Taguchi T, Sasaki J, Arai H, Sasaki T, Igarashi M, *Nakatsu F
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  • DOI: 10.1083/jcb.202103141
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• [Journal Article] PKCδ deficiency inhibits fetal development and is associated with heart elastic fiber hyperplasia and lung inflammation in adult PKCδ knockout mice (2021)
  • Author(s): 新野由子、川島育夫、井口義信、神田浩明、小倉潔、吉田薫、小野富男、山崎真弥、崎村建司、與五沢里美、吉田清嗣、塩田清二、後藤孝也
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  • Peer Reviewed / Open Access
• [Journal Article] PLEKHA5 regulates the survival and peritoneal dissemination of diffuse-type gastric carcinoma cells with Met gene amplification (2021)
  • Author(s): Yuko Nagamura, Makoto Miyazaki, Yoshiko Nagano, Masako Yuki, Kiyoko Fukami, Kazuyoshi Yanagihara, Kazuki Sasaki, Ryuichi Sakai, and Hideki Yamaguchi
  • Journal Title: Oncogenesis Volume: 10 Pages: 25
  • DOI: 10.1038/s41389-021-00314-1
  • Peer Reviewed / Open Access
• [Journal Article] Polygenic Risk Scores Differentiating Schizophrenia From Bipolar Disorder Are Associated With Premorbid Intelligence in Schizophrenia Patients and Healthy Subjects (2021)
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• [Journal Article] Proleg retractor muscles in Manduca sexta larvae are segmentally different suggesting anteroposterior specialization (2021)
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  • DOI: 10.1242/jeb.242508
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• [Journal Article] Proteomics-based target identification of natural products affecting cancer metabolism. (2021)
  • Author(s): Muroi M, Osada H.
  • Journal Title: J Antibiot Volume: 74 Pages: 639-650
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• [Journal Article] Quantitative morphometric analysis of molar teeth and alveolar bone in aged mice using micro-computed tomography. (2021)
  • Author(s): Ono R.*, Abe M.*, Koike N., Inokawa H., Tuchiya Y., Umemura Y., Sasawaki Y., Yamamoto T., Wakisaka S., Kanamura N., Yagita K.
  • Journal Title: Journal of Oral Bioscience
  • DOI: 10.1016/j.job.2021.07.006
  • Peer Reviewed
• [Journal Article] RAF1-MEK/ERK pathway-dependent ARL4C expression promotes ameloblastoma cell proliferation and osteoclast formation. (2021)
  • Author(s): Shinsuke Fujii, Takuma Ishibashi, Megumi Kokura, Tatsufumi Fujimoto, Shinji Matsumoto, ... Tamotsu Kiyoshima
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• [Journal Article] Ras-like Gem GTPase induced by Npas4 promotes activity-dependent neuronal tolerance for ischemic stroke. (2021)
  • Author(s): Takahashi H, Asahina R, Fujioka M, Matsui TK, Kato S, Mori E, Hioki H, Yamamoto T, Kobayashi K, Tsuboi A
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  • DOI: 10.1073/pnas.2018850118
  • Peer Reviewed
• [Journal Article] Reconstruction of Carbon Bond Frameworks via Oxapalladacycle Promoted by Synergistic Effect of Palladium Catalyst and Triethylborane (2021)
  • Author(s): Ryo Ninokata, Riho Korogi, Junya Nakao, Tsutomu Fukuda, Gen Onodera, Masanari Kimura
  • Journal Title: Synthesis Volume: 53 Pages: 3110-3120
  • DOI: 10.1055/a-1485-5781
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• [Journal Article] Regulation of HP1 protein by phosphorylation during transcriptional repression and cell cycle. (2021)
  • Author(s): Oki M, Masai H.
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• [Journal Article] Regulation of neutrophil functions by Hv1/VSOP voltage-gated proton channels. (2021)
  • Author(s): Yoshifumi Okochi, Yasushi Okamura.
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  • Peer Reviewed / Open Access
• [Journal Article] Resistance to chemical carcinogenesis induction via a dampened inflammatory response in naked mole-rats (2021)
  • Author(s): Kaori Oka(研究代表者、共第一著者), Shusuke Fujioka(共第一著者), Yoshimi Kawamura(共第一著者), Kimi Araki(研究協力者) Kyoko Miura(責任著者), et al.
  • Journal Title: bioRxiv
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• [Journal Article] Ribosome stalling caused by the Argonaute-miRNA-SGS3 complex regulates production of secondary siRNA biogenesis in plants. (2021)
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  • Journal Title: Cell Rep Volume: 35 Pages: 109300
  • DOI: 10.1016/j.celrep.2021.109300
  • Peer Reviewed / Open Access
• [Journal Article] Role of ferroptosis in nanofiber-induced carcinogenesis (2021)
  • Author(s): Toyokuni S, Ito F, Motooka Y
  • Journal Title: Metallomics Res Volume: 1 Pages: #MR202102
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• [Journal Article] Roles of Claspin in regulation of DNA replication, replication stress responses and oncogenesis in human cells. (2021)
  • Author(s): Hsiao H-W, Yang C-C, Masai H
  • Journal Title: Genome Instability & Disease Volume: 2 Pages: 263-280
  • DOI: 10.1007/s42764-021-00049-8
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• [Journal Article] Scent test using caenorhabditis elegans to screen for earlystage pancreatic cancer. (2021)
  • Author(s): 2) Asai, A., Konno, M., Ozaki, M., Kawamoto, K., Chijimatsu, R., Kondo, N., Hirotsu, T., Ishii, H.
  • Journal Title: Oncotarget Volume: 12 Pages: 1687-1696
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• [Journal Article] Schizophrenia-like behavioraliImpairments in mice with suppressed expression of Piccolo in the medial prefrontal cortex (2021)
  • Author(s): Nitta A, Izuo N, Hamatani K, Inagaki R, Kusui Y, Fu K, Asano T, Torii Y, Habuchi C, Sekiguchi H, Iritani S, Muramatsu SI, Ozaki N, Miyamoto Y.
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  • Peer Reviewed / Open Access
• [Journal Article] Selective autophagy (2021)
  • Author(s): Mohammad Omar Faruk, Yoshinobu Ichimura, Masaaki Komatsu
  • Journal Title: Cancer Science Volume: 00 Pages: 1-7
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• [Journal Article] Selectivity of mRNA degradation by autophagy. (2021)
  • Author(s): Makino S, Kawamata T, Iwasaki S, and Ohsumi Y
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  • Peer Reviewed / Open Access
• [Journal Article] Senescence-accelerated mouse prone 8 (SAMP8) mice exhibit reduced entoconid in the lower second molar. (2021)
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  • Peer Reviewed
• [Journal Article] Sirt7 deficiency attenuates neointimal formation following vascular injury by modulating vascular smooth muscle cells proliferation. (2021)
  • Author(s): Kimura Y, Izumiya Y, Araki S, Yamamura S, Hanatani S, Onoue Y, Ishida T, Arima Y, Nakamura T, Bober E, Braun T, Kaikita K, Yamagata K, Tsujita K
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• [Journal Article] SIRT7 regulates lipogenesis in adipocytes through deacetylation of PPARg2. (2021)
  • Author(s): Akter F, Tsuyama T, Yoshizawa T, Sobuz SU, Yamagata K
  • Journal Title: J Diabetes Investig
  • DOI: 10.1111/jdi.13567
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• [Journal Article] Skewed endosomal RNA responses from TLR7 to TLR3 in RNase T2-deficient macrophages (2021)
  • Author(s): Kaiwen Liu, Ryota Sato, Takuma Shibata, Ryosuke Hiranuma, Tatjana Reuter, Takeshi Ichinohe, Manabu Ozawa, Nobuaki Yoshida, Eicke Latz, Kensuke Miyake
  • Journal Title: International Immunology Volume: 33 Issue: 9 Pages: 479-490
  • DOI: 10.1093/intimm/dxab033
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Spliceostatin A interaction with SF3B1 limits U1 snRNP availability and causes premature cleavage and polyadenylation. (2021)
  • Author(s): Yoshimoto R, Chhipi Shrestha JK, ... Iwasaki S, and Yoshida M
  • Journal Title: Cell Chem Biol Volume: 28 Pages: 1356-1365
  • DOI: 10.1016/j.chembiol.2021.03.002
  • Peer Reviewed
• [Journal Article] Stabilization of telomeric G-quadruplex by ligand binding increases susceptibility to S1 nuclease (2021)
  • Author(s): Ryo Ishikawa, Mizuho Yasuda, Shogo Sasaki, Yue Ma, Kazuo Nagasawa, Masayuki Tera
  • Journal Title: Chem. Commun., Volume: 57 Pages: 7236-7239
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  • Peer Reviewed
• [Journal Article] Stereodivergent nitrocyclopropane formation during biosynthesis of belactosins and hormaomycins (2021)
  • Author(s): Shimo, S., Ushimaru, R., Engelbrecht, A., Harada, M., Miyamoto, K., Andreas, K., Uchiyama, M., Kaysser, L., Abe, I.
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  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Striatal Shati/Nat81-BDNF pathways determine the sensitivity to social defeat stress in mice through epigenetic regulation (2021)
  • Author(s): Miyanishi H, Muramatsu SI, Nitta A
  • Journal Title: Neuropsychopharmacology Volume: 14 Pages: 1594-1605
  • DOI: 10.1038/s41386-021-01033-2
  • Peer Reviewed
• [Journal Article] Structural basis for isomerization reactions in fungal tetrahydroxanthone biosynthesis and diversification (2021)
  • Author(s): Yang, J., Mori, T., Wei, X., Matsuda, Y., Abe, I.
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• [Journal Article] Sublethal neonicotinoid exposure attenuates the effects of electromagnetic fields on honey bee flight and learning (2021)
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  • Journal Title: Environmental Advances Volume: 4 Pages: 100051
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  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Synthesis and Structural Diversification of Artemisinins Towards the Generation of Potent Anti-malarial Agents (2021)
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• [Journal Article] Tamoxifen feeding method is suitable for efficient conditional knockout. (2021)
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• [Journal Article] Th2 cell-derived histamine is involved in nasal Th2 infiltration in mice. (2021)
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  • Journal Title: Inflamm Res. Volume: 70 Pages: 539-541
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• [Journal Article] Th2 cells and macrophages cooperatively induce allergic inflammation through histamine signaling. (2021)
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• [Journal Article] The contribution of low contrast-preferring neurons to information representation in the primary visual cortex after learning. (2021)
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• [Journal Article] The Dickkopfl and FOXM1 positive feedback loop promotes tumor growth in pancreatic and esophageal cancer (2021)
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  • Journal Title: Oncogene Volume: 40 Pages: 4486-4502
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• [Journal Article] The efficacy of memantine in the treatment of civilian posttraumatic stress disorder : an open label trial. (2021)
  • Author(s): Hori, H., Itoh, M., Matsui, M., Kamo, T., Saito, T., Nishimatsu, Y, Kito, S., Kida, S., Kim, Y.
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  • Peer Reviewed / Open Access
• [Journal Article] The In Vivo Selection Method in Breast Cancer Metastasis (2021)
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  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The Japanese Wild-Derived Inbred Mouse Strain, MSM/Ms in Cancer Research (2021)
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  • Journal Title: Cancers (Basel). Volume: 13 Issue: 5 Pages: 1026
  • DOI: 10.3390/cancers13051026
  • Peer Reviewed / Open Access
• [Journal Article] The IncRNA Caren antagonizes heart failure by inactivating DNA damage response and activating mitochondrial biogenesis. (2021)
  • Author(s): Michio Sato, ... Kumiko Yoshinobu, Mai Imasaka, Masatake Araki, ... Kimi Araki, Yuichi Oike
  • Journal Title: Nat Commun Volume: 12 Pages: 2529
  • DOI: 10.1038/s41467-021-22735-7
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] The membrane-linked adaptor FRS2beta fashions a cytokine-rich inflammatory microenvironment that promotes breast cancer carcinogenesis. (2021)
  • Author(s): Takeuchi Y, Kimura N, Murayama T, et al, Gotoh N
  • Journal Title: Proc. Natl, Acad, Sci, USA Volume: 118 Pages: e2103658118
  • DOI: 10.1073/pnas.2103658118
  • Peer Reviewed / Open Access
• [Journal Article] The multi-kinase inhibitor dasatinib suppresses autoinflammation and increases bone density in a mouse model for chronic recurrent multifocal osteomyelitis (2021)
  • Author(s): Ryo Yoshikawa, Koichiro Abe
  • Journal Title: Cell Biochem Funct. Volume: 39 Pages: 521-527
  • DOI: 10.1002/cbf.3617
  • Peer Reviewed
• [Journal Article] The parabrachial-to-amygdala pathway provides aversive information to induce avoidance behavior in mice. (2021)
  • Author(s): Mariko Ito, Masashi Nagase, Suguru Tohyama, Kaori Mikami, Fusao Kato, Ayako M Watabe.
  • Journal Title: Molecular Brain Volume: 14 Pages: 94
  • DOI: 10.1186/s13041-021-00807-5
  • Peer Reviewed / Open Access
• [Journal Article] The role of early visual experience in the development of spatial-frequency preference in the primary visual cortex (2021)
  • Author(s): Nishio N, Hayashi K, Ishikawa AW, Yoshimura Y
  • Journal Title: The Journal of Physiology Volume: 599 Issue: 17 Pages: 4131-4152
  • DOI: 10.1113/JP281463
  • Peer Reviewed
• [Journal Article] The transcriptome of wild-type and immortalized corneal epithelial cells (2021)
  • Author(s): Furuya K, Wu T, Orimoto A, Sugano E, Tomita H, Kiyono T, Kurose T, Takai Y, Fukuda T
  • Journal Title: Sci Data Volume: 8 Issue: 1 Pages: 126
  • DOI: 10.1038/s41597-021-00908-9
  • Peer Reviewed / Open Access
• [Journal Article] Thermographic imaging of mouse across circadian time reveals body surface temperature elevation associated with non-locomotor body movements. (2021)
  • Author(s): Shimatani H, Inoue Y, Maekawa Y, Miyake T, Yamaguchi Y, and Doi M
  • Journal Title: PLoS One Volume: 16 Pages: e0252447
  • DOI: 10.1371/journal.pone.0252447
  • Peer Reviewed / Open Access
• [Journal Article] Topoisomerase IIβ immunoreactivity (IR) co-localizes with neuronal marker-IR but not glial fibrillary acidic protein-IR in GLI3-positive medulloblastomas : an immunohistochemical analysis of 124 medulloblastomas from the Japan Children's Cancer Group (2021)
  • Author(s): Miyahara H, Natsumeda M, Kanemura Y, Yamasaki K, Yoshimura J, Fujii Y, Suenobu S, Ihara K, Hara J, Kakita A, Yoshida M, Iwasaki Y
  • Journal Title: Brain Tumor Pathol Volume: 49 Issue: 3 Pages: 527-534
  • DOI: 10.1007/s10014-021-00396-0
  • Peer Reviewed
• [Journal Article] Transient expansion of the expression region of Hsdllbl, encoding 11β-hydroxysteroid dehydrogenase type 1, in the developing mouse neocortex. (2021)
  • Author(s): Doi M, Oka Y, Taniguchi M, Sato M.
  • Journal Title: J. Neurochem Volume: 00 Pages: 1-11
  • DOI: 10.1111/jnc.15505
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Transmembrane protein 168 mutation reduces cardiomyocyte cell surface expression of Nav1.5 through αB-crystallin intracellular dynamics. (2021)
  • Author(s): Nguyen LKC, Shimizu A, Soh JEC, Komeno M, Sato A, Ogita H.
  • Journal Title: J Biochem
  • DOI: 10.1093/jb/mvab066
  • Peer Reviewed
• [Journal Article] Tumor necrosis factor α negatively regulates the retrieval and reconsolidation of hippocampus-dependent memory. (2021)
  • Author(s): Takahashi, S., Fukushima, H., Yu, Z., Tomita, H., Kida, S.*
  • Journal Title: Brain, Behavior, and Immunity Volume: 94 Pages: 79-88
  • DOI: 10.1016/j.bbi.2021.02.033
  • Peer Reviewed
• [Journal Article] Txnl mutation causes epilepsy associated with vacuolar degeneration in the midbrain (2021)
  • Author(s): Iori Ohmori, Mamoru Ouchida, Hirohiko Imai, Saeko Ishida, Shinya Toyokuni, Tomoji Mashimo
  • Journal Title: bioRxiv
  • DOI: 10.1101/2021.10.07.463470
  • Open Access
• [Journal Article] Tyrosine hydroxylase activity is regulated through the modification of the 176th cysteine residue. (2021)
  • Author(s): Inukai, S., Hara, S., and Ichinose, H.
  • Journal Title: Biochem. Biophys. Res. Commun. Volume: 589 Pages: 209-214
  • DOI: 10.1016/j.bbrc.2021.12.024
  • Peer Reviewed
• [Journal Article] VGLL3 activates inflammatory responses by inducing interleukin-1α secretion (2021)
  • Author(s): Yuki Takakura, Naoto Hori, Natsumi Terada, Moeka Machida, Naoto Yamaguchi, Hiroyuki Takano, Noritaka Yamaguchi
  • Journal Title: FASEB Journal Volume: 11 Pages: e21996
  • DOI: 10.1096/fj.202100679RR
  • Peer Reviewed
• [Journal Article] Vinylnaphthalene-bearing hexaoxazole as a fluorescence turn-on type G-quadruplex ligand (2021)
  • Author(s): Yue Ma, Yuki Wakabayashi, Naruyuki Watatani, Ryota Saito, Takatsugu Hirokawa, Masayuki Tera, Kazuo Nagasawa
  • Journal Title: Org. Biomol. Chem
  • DOI: 10.1039/D10B01500A
  • Peer Reviewed
• [Journal Article] Zfhx4 regulates endochondral ossification as the transcriptional platform of Osterix. (2021)
  • Author(s): Nakamura E., Hata K., Takahata Y., Kurosaka H., Abe M., et al
  • Journal Title: Commun. Biol. Pages: 1258
  • DOI: 10.1038/s42003-021-02793-9
  • Peer Reviewed / Open Access
• [Journal Article] β-NAD as a building block in natural product biosynthesis. (2021)
  • Author(s): Barra, L., # Awakawa, T., # Shirai, K., Hu, Z., Bashiri, G., Abe, I. (#equall contribution)
  • Journal Title: Nature Volume: 600 Pages: 754-758
  • DOI: 10.1038/s41586-021-04214-7
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] オレキシンと情動 (2021)
  • Author(s): 山中章弘
  • Journal Title: 生体の科学 Volume: 72 Issue: 5 Pages: 475-477
• [Journal Article] ノックアウトラットによる2種類のGABA合成酵素アイソフォームの機能的役割の解明 (2021)
  • Author(s): 藤原和之、柿崎利和、姜玮茹、宮田茂雄、柳川右千夫
  • Journal Title: 細胞 Volume: 53 Pages: 443-447
• [Journal Article] 高脂肪食摂取加齢マウスにおける亜鉛の長期間過剰投与が学習・記憶能に及ぼす影響 (2021)
  • Author(s): 吉田 香, 魏 民, 藤岡正喜, 寺本 勲
  • Journal Title: Trace Nutrients Research Volume: 38 Pages: 7-13
  • Peer Reviewed / Open Access
• [Journal Article] 統合失調症の認知機能障害を改善するエピゲノム治療薬の開発 (2021)
  • Author(s): 福田茉由, 向井淳
  • Journal Title: 精神科 Volume: 38 Issue: 2 Pages: 220-228
• [Journal Article] 疼痛医学におけるPrecision Medicine(精密医療) -P2Y12受容体と痛み (2021)
  • Author(s): 土田陸平, 住谷昌彦, 阿部博昭, 内田寛治
  • Journal Title: 臨床麻酔 Volume: 45 Pages: 137-145
• [Journal Article] 胚盤胞補完法とES細胞を用いた甲状腺再生 (2021)
  • Author(s): 冉慶松、周啓亮、小田佳奈子、泰江章博、阿部学、笹岡俊邦、崎村建司、味岡洋一、西條康夫
  • Journal Title: 日本再生医療学会総会(Web) Volume: 20 Pages: ROMBUNNO. P-01-03
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] 胚盤胞補完法を用いた多能性幹細胞由来肺の作出 (2021)
  • Author(s): 西條康夫、周啓亮、冉慶松、北原哲彦、小田佳奈子、泰江章博、笹岡俊邦、叶許緑、阿部学、崎村建司、土田正則、味岡洋一
  • Journal Title: 日本呼吸器学会誌(Web) (Annals of the Japanese Respiratory Society (Web)) 増刊号 Volume: 10
  • Peer Reviewed
• [Journal Article] 疼痛のバイオマーカー探索 (2020)
  • Author(s): 土田陸平, 阿部博昭, 井上玲央, 水枝谷和仁, 東賢志, 住谷昌彦.
  • Journal Title: 実験医学 Volume: 38 Pages: 425-430
• [Presentation] GABAニューロン研究のための遺伝子改変ラット (2022)
  • Author(s): 柳川右千夫
  • Organizer: 第15回ラットリソース・リサーチ研究会
• [Presentation] GABA合成酵素の遺伝子機能探索 : マウスとラットのノックアウト動物を利用した比較研究 (2022)
  • Author(s): 柳川右千夫
  • Organizer: 先端モデル動物支援プラットフォーム2021年度成果発表会
  • Invited
• [Presentation] Novel protective role of RhoA in vascular smooth muscle cells against aortic aneurysm formation (2022)
  • Author(s): Md Rasel Molla、清水昭男、Nor Idayu A. Rahman、Joanne Ern Chi Soh、Le Kim Chi Nguyen、Mahbubur Rahman Khan、岡本(田中)三紀、高島範之、佐藤朗、鈴木友彰、扇田久和
  • Organizer: 日本循環器学会
  • Invited
• [Presentation] Palmitoyl piperidinopiperidine induces selective anticancer activity against human colon carcinoma cell lines (2022)
  • Author(s): Sultana Nahida、深町勝巳、松本晴年、酒々井眞澄
  • Organizer: 第38回 日本毒性病理学会
  • Int'l Joint Research
• [Presentation] エピゲノム異常疾患の病態解明と病因再定義 (2022)
  • Author(s): 副島英伸
  • Organizer: AMED難治性疾患実用化研究事業 G-2 「精緻エピゲノム解析技術開発とIRUD未解明症例への応用」 R3年度班会議
• [Presentation] オプトジェネティクスを用いた光による痛み制御 : ナトリウムチャネルNaV1.7・NaV1.8・NaV1.9を標的とした遺伝子改変マウスの開発と疼痛行動の比較 (2022)
  • Author(s): 丸田豊明、興梠聡志、日髙康太郎、越田智広、白阪哲朗、恒吉勇男
  • Organizer: 第69回日本麻酔科学会
• [Presentation] マルチスケールイメージングによる脳機能発現メカニズムの探求 (2022)
  • Author(s): 小山内 実
  • Organizer: 令和3年度 京都大学 霊長類研究所 共同利用研究会 「霊長類の先進的遺伝子改変モデルを用いた神経ネットワークの構造と機能の解明」
  • Invited
• [Presentation] ミクログリアによるニューロンーアストロサイト間情報伝達の制御機構 (2022)
  • Author(s): 鈴木秀明、繁冨英治、平山幸歩、高橋由香里、池中一裕、田中謙二、加藤総夫、尾藤晴彦、小泉修一
  • Organizer: 第95回日本薬理学会年会
• [Presentation] 癌抑制因子P53を制御する核小体ストレス応答を利用した新たな抗がん剤治療戦略 (2022)
  • Author(s): 石原由香, 川畑拓斗、古川龍彦、河原康一
  • Organizer: 日本薬学会第142年会
• [Presentation] 極微細蛍光内視鏡システムによるマウス両側海馬CA1の感覚情報入力に対する応答の計測 (2022)
  • Author(s): 川淵 公美子, 大川 宜昭, 瀬戸川 将, 増﨑 紘平, 田村 篤史, 小山内 実
  • Organizer: 2021年度先端モデル動物支援プラットフォーム成果発表会
• [Presentation] 黒ショウガ(Kaempferia parviflora)による脳認知機能改善効果の検証 (2022)
  • Author(s): 吉田 泉, 吉田 香, 高橋 有志, 藤田 和弘
  • Organizer: 日本農芸化学会2022年度京都大会
• [Presentation] 細胞外ATPを介したグリアーニューロン情報伝達の時空間ダイナミクス (2022)
  • Author(s): 繁冨英治、小泉修一
  • Organizer: 第99回日本生理学会大会
• [Presentation] 社会的敗北観察ストレスによるコカイン欲求増大の脳内メカニズム (2022)
  • Author(s): 齋藤惇、本野芽衣、乙田篤輝、張たん、江崎博仁、村田陽香、西谷直也、出山諭司、金田勝幸
  • Organizer: 日本薬学会第142年会
• [Presentation] 神経生理学におけるメレオロジカルな誤謬を避けるためのマルチスケールイメージング (2022)
  • Author(s): 小山内 実
  • Organizer: 第99回 日本生理学会大会 公募シンポジウム「部分と全体学による脳の理解」
  • Invited
• [Presentation] 体細胞分裂型から減数分裂型の細胞周期への切り替え機構 (2022)
  • Author(s): 石黒啓一郎
  • Organizer: 先端モデル動物支援プラットフォーム令和3年度成果発表会(大津)
  • Invited
• [Presentation] A functional polymorphism in the 3'UTR of Pakl regulates alternative polyadenylation and affects skin cancer susceptibility in mice (2021)
  • Author(s): Kazuhiro Okumura, Megumi Saito, Eriko Isogai, Yuichi Wakabayashi
  • Organizer: 第80回日本癌学会学術総会
• [Presentation] A myosin/septin-dependent postsynaptic regulation required for memory consolidation (2021)
  • Author(s): Ageta-Ishihara N, Fukazawa Y, Takao K, Kengaku M, Miyakawa T, Inokuchi K, Bito H, Kinoshita M.
  • Organizer: 第44回 日本神経科学大会、第1回CJK国際会議
  • Int'l Joint Research
• [Presentation] A new kind of positive feed-back regulation via the organelle extension (2021)
  • Author(s): Ageta-Ishihara N
  • Organizer: RIKEN BDR ‘Women and Future in Science’ Seminar
  • Invited
• [Presentation] A novel bipolar mice model by Teneurin-4 reduction in the prefrontal cortex (2021)
  • Author(s): T Asano, K Tokoro, T Horita, N Izuo, S Muramatsu, A Nitta
  • Organizer: A novel bipolar mice model by Teneurin-4 reduction in the prefrontal cortex
  • Int'l Joint Research
• [Presentation] A novel inhibitor of one carbon metabolism with Chkl inhibitor is a rational combination strategy to treat breast cancer (2021)
  • Author(s): 西村建徳, Jin Lee, Chen Xiaoxi, 石川聡子, Li Mengjiao, Yuming Wang, 大黒多希子, 東條有伸、後藤典子
  • Organizer: 第80回日本癌学会学術総会
• [Presentation] A novel LUBAC-associated protein plays important roles in inflammatory response through regulation of programmed cell death. (2021)
  • Author(s): Tran Thi Thuy Linh、清水 康平、及川 大輔、高橋 宏隆、澤崎 達也、徳永 文稔
  • Organizer: 第94回日本生化学会大会
• [Presentation] A novel LUBAC-associated protein regulates NF-kB activation, apoptosis and necroptosis pathway. (2021)
  • Author(s): 清水 康平, Tran Thi Thuy Linh, 及川 大輔, 高橋 宏隆、澤崎 達也、徳永 文稔
  • Organizer: 第44回日本分子生物学会年会
• [Presentation] A novel molecular mechanism regulating chondrocyte cell polarity that is essential for endochondral ossification. (2021)
  • Author(s): Koji Kikuchi, Mami Nakagawa, Toshihiko Fujimori, Kei-ichiro Ishiguro, Kimi Araki, Akira Nakamura, Makoto Suzuki, and Hiroyuki Nakanishi
  • Organizer: 第54回日本発生生物学会年会
• [Presentation] A novel molecular mechanism regulating chondrocyte cell polarity that is essential for endochondral ossification. (2021)
  • Author(s): 菊池 浩二、中川 真美, 藤森 俊彦、石黒 啓一郎、荒木 喜美、中村 輝、鈴木 誠、中西 宏之
  • Organizer: 第73回日本細胞生物学会大会
• [Presentation] A robust and sustained circadian rhythm of Per2 : : Luc expression in the mouse meibomian gland acinar cells (2021)
  • Author(s): グエン ファム カン ティエン、三宅崇仁、土居雅夫
  • Organizer: 第28回日本時間生物学会年会
• [Presentation] A specific eIF4A paralog facilitates LARP1-mediated translation repression during mTORC1 inhibition (2021)
  • Author(s): 岩崎信太郎
  • Organizer: 第59回日本生物物理学学会年会
  • Invited
• [Presentation] A specific eIF4A paralog facilitates LARP1-mediated translation repression during mTORC1 inhibition. (2021)
  • Author(s): 岩崎信太郎
  • Organizer: Mini-symposium on RNA Biology and Therapeutics [Basic Science (IBS) and Seoul National University (SNU), Korea]
  • Int'l Joint Research / Invited
• [Presentation] Abnormalities in cortical architecture caused by modulation of cytokine balance. (2021)
  • Author(s): Tetsuya Sasaki, Masae Ohtsuka, Hiroko Suzaki, Yosuke Takei.
  • Organizer: The 44th Annual Meeting of the Japan Neuroscience Society
• [Presentation] Activity recording of orexin neurons during sleep and cataplexy. (2021)
  • Author(s): 伊藤洋人、深津紀暁、山中章弘.
  • Organizer: 日本睡眠学会第46回定期学術集会
• [Presentation] ADHD関連化学物質の生化学的基盤 (2021)
  • Author(s): 石堂正美
  • Organizer: 第94回日本生化学会
• [Presentation] Adipsin-dependent HGF secretion from adipocytes promotes cancer stem cell properties inof breast cancer cells. (2021)
  • Author(s): Masahiro Mizuno, Behnoush Khaledian, Masao Maeda, Shiori Takusagawa, Manaka Yano, Naoya Asai, Yohei Shimono
  • Organizer: 第80回日本癌学会学術総会
• [Presentation] Analysis of DNA damage-induced activation of the SAPK signaling pathways (2021)
  • Author(s): 塩崎ゆかり
  • Organizer: 第80回日本癌学会学術総会
• [Presentation] Analysis of the subcellular localization of TMEM180, which is highly expressed in colorectal cancer cells (2021)
  • Author(s): Takahiro Anzai, Masahiro Yasunaga, Yasuhiro Matsumura
  • Organizer: 第80回日本癌学会学術総会
• [Presentation] APEX2を用いた近位ビオチン標識法と質量分析を活用した熱刺激誘導性液-液相分離顆粒コアタンパク質の探索 (2021)
  • Author(s): 松田碧、中村貴紀、小迫英尊、武川睦寛
  • Organizer: 第72回日本電気泳動学会総会
• [Presentation] Application of organoids to breast cancer research. (2021)
  • Author(s): Shimono Y, Nishimura T, Kono S, Hayashi T, Watanabe T, Maeda M, Kakeji Y, Kawada K, Asai N, Takao S, Minami H, Kijima Y, Suzuki M, Gotoh N, et al.
  • Organizer: 第80回日本癌学会学術総会
  • Invited
• [Presentation] Aspergillus lentulusの生産する新規天然物lentopeptin A, Bの構造決定と生合成解析 (2021)
  • Author(s): 松原有也、岸本真治、渡辺賢二
  • Organizer: 日本生薬学会第67回年会
• [Presentation] Aspergillus属糸状菌が産生する免疫抑制化合物sphingofungin類の生合成機構の解明 (2021)
  • Author(s): 永井拓実、岸本真治、渡辺賢二
  • Organizer: 日本生薬学会第67回年会
• [Presentation] Association of Rifl with nuclear membrane is essential for genome-wide replication timing regulation (2021)
  • Author(s): Tomohiro Iguchi, Sayuri Ito, Naoko Kakusho, Satoshi Yamazaki, Asami Oji, Rino Fukatsu, Ichiro Hiratani, Hiroyuki Sasanuma, Hisao Masai
  • Organizer: 第44回日本分子生物学会年会
  • Invited
• [Presentation] Autocrine regulation of adipocytes promotes cancer stem cell properties in breast cancers (2021)
  • Author(s): Behnoush Khaledian, Masahiro Mizuno, Masao Maeda, Shiori Takusagawa, Manaka Yano, Naoya Asai, Yohei Shimono
  • Organizer: 第80回日本癌学会学術総会
• [Presentation] Cellular functions regulated by complex-type ubiquitination including linear polyubiquitin chain (2021)
  • Author(s): Tokunaga F, Terawaki S, Oikawa D, Shimizu K.
  • Organizer: 第44回日本分子生物学会年会
  • Invited
• [Presentation] Characteristics of visuospatial analyses during the measure of subjective visual vertical in acute stroke patients. (2021)
  • Author(s): Yasuaki Arima, Kae Nakamura, Kimihiko Mori, Kimitaka Hase
  • Organizer: 44th Annual Meeting of the Japan Neuroscience Society
• [Presentation] Characterization of Luminal High-Osteolytic Breast Cancer Cell Lines (2021)
  • Author(s): Han Yuxuan, Jun Nakayama, Mitsuru Futakuchi, Shinya Watanabe, Kentaro Semba
  • Organizer: 第44回日本分子生物学会年会
• [Presentation] Characterization of Luminal High-Osteolytic Breast Cancer Cell Lines (2021)
  • Author(s): Han Yuxuan, Jun Nakayama, Mitsuru Futakuchi, Emi Ito5, Shinya Watanabe, Kentaro Semba
  • Organizer: 第80回日本癌学会学術総会
• [Presentation] Chromatin regulation that involves assembly of protein, lipid and DNA with a special higher-order structure (2021)
  • Author(s): 正井久雄
  • Organizer: 第94回日本生化学会大会
  • Invited
• [Presentation] Circadian clock : disease etiology and drug target exploration (2021)
  • Author(s): Masao Doi
  • Organizer: The 5th Asian Forum on Chronobiology
  • Int'l Joint Research / Invited
• [Presentation] Claspin is required for growth recovery from serum starvation through regulating the PI3K-PDK1-mTOR pathway. (2021)
  • Author(s): Chi-Chun Yang, Hisao Masai
  • Organizer: Cold Spring Harbor Asia Conference, DNA METABOLISM, GENOMIC STABILITY & HUMAN DISEASE
  • Int'l Joint Research / Invited
• [Presentation] Comparative analyses of neuronal activation in the spinal dorsal horn for mechanical allodynia after Spared nerve injury between wild-type and BEGAIN-knockout mice (2021)
  • Author(s): Tayo Katano, Manabu Abe, Masahiko Watanabe, Kenji Sakimura and Takuya Kobayashi
  • Organizer: 第44回日本神経科学学会/CJK第1回国際会議
  • Int'l Joint Research
• [Presentation] Competitive elimination of tight junction deficient cells regulate epithelial barrier homeostasis (2021)
  • Author(s): Tetsuhisa Otani, Mikio Furuse
  • Organizer: 4th International Tight Junction Conference
  • Int'l Joint Research
• [Presentation] Competitive elimination of tight junction deficient cells regulate epithelial barrier homeostasis (2021)
  • Author(s): Tetsuhisa Otani, Mikio Furuse
  • Organizer: The 51st NIPS International Symposium
  • Int'l Joint Research
• [Presentation] Cortical layers receive kcnabl-expressing neurons from the subplate (2021)
  • Author(s): Murtala Hamza Yahaya, Yuichiro Oka, Makoto Sato
  • Organizer: 第44回 日本神経科学大会 第1回CJK国際会議
  • Int'l Joint Research
• [Presentation] COVID-19患者におけるネオプテリンおよび炎症マーカーレベルの解析 (2021)
  • Author(s): 原怜、佐南谷瑞、立川夏夫,、吉村幸浩、宮田順之、佐々木裕明、黒田理佐、上國料千夏、江口智洋、新山修平、垣花泰之、一瀬宏
  • Organizer: 第34回日本プテリジン研究会
• [Presentation] CRMP1 modulates motor function of amyotrophic lateral sclerosis by phosphorylation at Ser 522 (2021)
  • Author(s): Tetsuya Asano, Haruko Nakamura, Fumio Nakamura, Yayoi Kimura, Yoshio Goshima, Hiroshi Takano, Ryoji Yao, Hideyuki Takeuchi, Hiroshi Doi, Fumiaki Tanaka, et al.
  • Organizer: Pan-Asia Consortium for Treatment and Research in ALS (PACTALS) 2021 NAGOYA
  • Int'l Joint Research
• [Presentation] D1及びD2ドーパミン受容体を介する神経伝達による運動制御と学習記憶の仕組みの理解 (2021)
  • Author(s): 笹岡 俊邦、齊藤 奈英、田井中 一貴、Macpherson Tom、疋田 貴俊、山口 瞬、板倉 誠、阿部 学、崎村 建司
  • Organizer: 第43回日本生物学的精神医学会
  • Invited
• [Presentation] Development of a chondroblastic osteosarcoma model from iPSC-based neural crest cells (2021)
  • Author(s): 迎恭輔、竹信尚典、神田浩明、大平美紀、遠藤悠紀、春田雅之、杉野 隆一、佐藤俊平、戸口田淳也、長船健二、中畑龍俊、上條岳彦
  • Organizer: 第80回日本癌学会学術総会
• [Presentation] Development of a new chemogenetic neuronal activation system based on insect Ionotropic Receptors. (2021)
  • Author(s): Iguchi, Y., Fukabori, R., Kato, S., Takahashi, K., Eifuku, S., ..., & Kobayashi, K.
  • Organizer: The 44th Annual Meeting of the Japan Neuroscience Society
• [Presentation] Development of epigenome therapeutic agents and treatments to improve cognitive impairments in schizophrenia (2021)
  • Author(s): 福田 茉由、Joseph A. Gogos、向井 淳
  • Organizer: 日本神経科学会
• [Presentation] Dietary magnesium deficiency impairs hippocampus-dependent memories and induces neuroinflammation in mouse. (2021)
  • Author(s): Satoshi Kida
  • Organizer: International Society for the Development of Research on Magnesium (SDRM)
  • Int'l Joint Research / Invited
• [Presentation] Differential reduction of monoamine neurotransmitters and PTSD-like behavior in mice defective in the regeneration of tetrahydrobiopterin. (2021)
  • Author(s): 鈴木実乃里, 宮嶋克也, 須藤雄介, 実近翔, 原慶賢, 堀口美恵子, 原怜, 鷲見-一瀬千穂, 近藤一直, 短田浩一, 高雄啓三, 宮川剛, 一瀬宏
  • Organizer: 第51回日本神経精神薬理学会
• [Presentation] Dipeptidyl peptidase Ⅲの糖尿病性腎臓病抑制機序 (2021)
  • Author(s): 米野雅大、Md Rasel Molla、清水昭男、扇田久和
  • Organizer: 日本生化学会近畿支部例会
  • Int'l Joint Research
• [Presentation] DNA損傷ストレスにより活性化するシグナル伝達経路と細胞運命決定機構の解析 (2021)
  • Author(s): 久保田 裕二、塩崎 ゆかり、武川 睦寛
  • Organizer: 第15回 日本臨床ストレス応答学会大会
• [Presentation] Dominant processing of social, rather than reward information in the lateral nucleus of primate amygdala. (2021)
  • Author(s): Koji Kuraoka, Kae Nakamura
  • Organizer: 44th Annual Meeting of the Japan Neuroscience Society
• [Presentation] Drug screening of anti-tumor effects on canine urothelial carcinoma cell lines 犬尿路上皮癌細胞株における抗腫瘍効果を指標とした薬剤スクリーニング (2021)
  • Author(s): 小寺優佳、曽我恭花、加藤大貴、品田真央、池田凡子、衛藤翔太郎、吉竹涼平、高橋洋介、橋本裕子、西村亮平、中川貴之
  • Organizer: 第80回 日本癌学会学術集会
• [Presentation] Dynamic interaction between emotional and cognitive signal in primate dorsal raphe nucleus. (2021)
  • Author(s): Masaharu Yasuda, Yasumasa Ueda, Kae Nakamura
  • Organizer: 44th Annual Meeting of the Japan Neuroscience Society
• [Presentation] Effects of RORγt overexpression on the central nervous system and behaviors. (2021)
  • Author(s): Tetsuya Sasaki, Aki Takahashi, Satoru Takahashi, Yosuke Takei.
  • Organizer: The 126th Annual Meeting of the Japanese Association of Anatomists. / The 98th Annual Meeting of The Physiological Society of Japan.
• [Presentation] Effects of Shati/Nat81 overexpression on recovery of cognitive dysfunction in a mouse model of Alzheimer's disease. (2021)
  • Author(s): K Chino, N Izuo, T Kuboyama, C Tohda, S Muramatsu.
  • Organizer: AsCNP (Asian College of Neuropsychopharmacology)
  • Int'l Joint Research
• [Presentation] eIF2B結合性ウイルスタンパク質NSsによる統合的ストレス応答抑制 (2021)
  • Author(s): 岩崎信太郎
  • Organizer: 第94回日本生化学大会
  • Invited
• [Presentation] Elevated maternal retinoic acid-related orphan receptor-γt enhances the effect of poly (I : C) in inducing fetal loss. (2021)
  • Author(s): Tetsuya Sasaki, Masae Ohtsuka, Satoru Takahashi, Yosuke Takei.
  • Organizer: The 45th Annual Meeting of the Japanese Society of Women's Nutrition and Metabolism/ The 10th Japan DOHaD Society Academic Meeting
• [Presentation] Elevated maternal RORγt enhances the effect of polyinosinic-polycytidylic acid in inducing fetal loss. (2021)
  • Author(s): Tetsuya Sasaki, Masae Ohtsuka, Satoru Takahashi, Yosuke Takei.
  • Organizer: The 127th Annual Meeting of The Japanese Association of Anatomists.
• [Presentation] Elucidation of the activation and drug-resistance mechanisms of diseases-associated MEK1 mutants 癌・先天性疾患を導くMEK1遺伝子変異体の異常活性化機構と薬剤耐性獲得機序の解明 (2021)
  • Author(s): 久保田 裕二、藤岡 優子、野田 展生、武川 睦寛
  • Organizer: 第80回 日本癌学会学術総会
• [Presentation] Emergence of stress tolerance in fear memory by a spliced prion-like domain of ILF3 (2021)
  • Author(s): 椎名伸之
  • Organizer: 第44回日本神経科学大会・第1回CJK国際会議
  • Int'l Joint Research / Invited
• [Presentation] ERK活性依存的に発現抑制されるミトコンドリア局在タンパク質の解析 (2021)
  • Author(s): 櫻井文香
  • Organizer: 第44回日本分子生物学会
• [Presentation] ERK誘導性の発癌を阻害する新規癌抑制遺伝子の同定 (2021)
  • Author(s): 高木祐輔
  • Organizer: 日本癌学会学術総会
• [Presentation] Expression of IL-17RA in the cerebral cortex of mice during postnatal development and its alteration by maternal immune activation. (2021)
  • Author(s): Yosuke Takei, Peiyi Bao, Masae Ohtsuka, Hiroko Suzaki, Suguru Iwata, Tetsuya Sasaki.
  • Organizer: The 127th Annual Meeting of the Japanese Association of Anatomists.
• [Presentation] Functional mechanism of polarized phosphoinositides distribution generated by voltage-sensing phosphatase in sperm flagellum (2021)
  • Author(s): Kawai T, Okamura Y.
  • Organizer: 第126回日本解剖学会・第98回日本生理学会大会
• [Presentation] Genome-wide survey of ribosome traverse (2021)
  • Author(s): 岩崎信太郎
  • Organizer: R&D戦略委員会第1回企画シンポジウム
  • Invited
• [Presentation] Gravity activates mitochondrial translation through cell adhesion-FAK axis (2021)
  • Author(s): Iwasaki S
  • Organizer: The 44th Annual Meeting of The Molecular Biology Society of Japan (MBSJ 2021)
  • Int'l Joint Research / Invited
• [Presentation] GREB1 isoform 4はピリミジン合成を介して悪性黒色腫細胞の増殖能を促進する (2021)
  • Author(s): 新澤康英, 松本真司、種村篤、横井一範、藤本学、二村圭祐、曽我朋義、菊池 章
  • Organizer: 第44回日本分子生物学会年会
• [Presentation] Hippocampal 7a-hydroxylated neurosteroids upregulated in a training-dependent manner are essential for remote memory formation. (2021)
  • Author(s): 清水貴美子、前畑佳納子、池野 知子、Qiuyi Wang、衛 澤峰、櫻井 文香、Pan Yue、高尾 敏文、深田 吉孝
  • Organizer: 第44回日本神経科学大会/CJK第1回国際会議
  • Int'l Joint Research / Invited
• [Presentation] HNFla controls both insulin and glucagon secretion in pancreatic islets (2021)
  • Author(s): Kazuya Yamagata
  • Organizer: The 64th Annual Meeting of the Japan Diabetes Society
  • Invited
• [Presentation] Identification of Chondrocyte-specific Sox9 Enhancers Important for Skeletal Development (2021)
  • Author(s): S. Kobayashi, K. Hata, Y. Takahata, T. Murakami, N. Uzawa, R. Nishimura
  • Organizer: American Society for Bone and Mineral Research 2021 Annual Meeting
• [Presentation] Identification of neural pathway which converts circadian rhythm to sleep/wakefulness. (2021)
  • Author(s): 山中章弘
  • Organizer: 2020 Oriental International Sleep Medicine Summit Forum
  • Int'l Joint Research / Invited
• [Presentation] Identification of OTUD1 deubiquitinase as a regulator for innate immune responses, cell death, and inflammatory bowel disease (2021)
  • Author(s): Oikawa D, Gi M, Kosako H, Shimizu K, Shiota M, Takahashi H, Sawasaki T, Tokunaga F.
  • Organizer: 第94回日本生化学会大会
  • Invited
• [Presentation] IgA-deficiency breaks immunological and neurological homeostasis (2021)
  • Author(s): 安達貴弘
  • Organizer: 日本免疫学会 第50回学術集会
• [Presentation] Innate drug resistance of ALDH1A3-enriched cancer cell subpopulation and its plasticity in gastric cancer (2021)
  • Author(s): Tetsuo Mashima, Ryuhei Kawakami, Koshi Kumagai, Takeshi Sano, Kensei Yamaguchi, Hiroyuki Seimiya
  • Organizer: 第80回日本癌学会学術総会
• [Presentation] Ionotropic receptor-mediated chemogenetic activation of LC neurons enhances conditioned memory retrieval through adrenergic receptor subtypes in the basolateral amygdala. (2021)
  • Author(s): 3. Fukabori, R., Iguchi, Y., Kato, S., Takahashi, K., Eifuku, S., ..., & Kobayashi, K.
  • Organizer: The 44th Annual Meeting of the Japan Neuroscience Society
• [Presentation] iPS細胞由来神経堤細胞による軟骨芽細胞型骨肉腫モデル開発 (2021)
  • Author(s): 迎恭輔、竹信尚典、神田浩明、大平美紀、遠藤悠紀、春田雅之、杉野隆一、佐藤俊平、戸口田淳也、長船健二、中畑龍俊、上條岳彦
  • Organizer: 第80回日本癌学会学術総会
• [Presentation] Key roles of CB1 receptors in the amygdala : ACPA induced place preference. (2021)
  • Author(s): T Tokutake, T Asano, S Nakaya, N Izuo, A Nitta.
  • Organizer: AsCNP (Asian College of Neuropsychopharmacology)
  • Int'l Joint Research
• [Presentation] LINE-1と精神神経疾患 : 転移の分子機構と新規解析技術の開発 (2021)
  • Author(s): 岩本和也
  • Organizer: 第43回生物学的精神医学会・第51回日本神経精神薬理学会合同年会
  • Invited
• [Presentation] Long non-coding RNAの翻訳と脳の進化 (2021)
  • Author(s): 松本 有樹修
  • Organizer: 第44回日本神経科学大会
  • Int'l Joint Research / Invited
• [Presentation] LUBACユビキチンリガーゼと直鎖状ユビキチン鎖が筋萎縮性側索硬化症関連 タンパク質TDP-43の細胞質内凝集形成を促進する (2021)
  • Author(s): 寺脇 正剛, 張 強, 及川 大輔, 林 邦忠, 布村 一人, 駒川 晋輔, 臼杵 克之助, 徳永 文稔
  • Organizer: 第44回日本分子生物学会年会
• [Presentation] Mathematical modeling of the molecular mechanism underlying the recruitment of centriole biogenesis regulators to mother centrioles (2021)
  • Author(s): 中村 貴紀、西住(渡海) 紀子、中澤 嵩、森 竜樹、鈴木 貴、武川 睦寛
  • Organizer: 第80回日本癌学会学術総会
  • Invited
• [Presentation] MDMAによる向社会効果に対する扁桃体基底外側核5-HT1A受容体の役割 (2021)
  • Author(s): 江崎博仁、佐々木祐輝、大嶋祥高、釜田ひかり、向井沙和子、中田早音、齊藤隆太郎、西谷直也、出山諭司、金田勝幸
  • Organizer: 次世代を担う若手のための創薬・医療薬理シンポジウム2021
• [Presentation] MDMAによる向社会効果誘導における扁桃体基底外側核5-HT1A受容体の関与 (2021)
  • Author(s): 佐々木祐輝、大嶋祥高、江崎博仁、釜田ひかり、向井沙和子、中田早音、齊藤隆太郎、西谷直也、出山諭司、金田勝幸
  • Organizer: 第139回日本薬理学会近畿部会
• [Presentation] MDMAの向社会効果における扁桃体基底外側核5-HT1A受容体の関与 (2021)
  • Author(s): 江崎博仁、佐々木祐輝、大嶋祥高、釜田ひかり、向井沙和子、中田早音、齊藤隆太郎、西谷直也、出山諭司、金田勝幸
  • Organizer: 生体機能と創薬シンポジウム2021
• [Presentation] METTL18-mediated histidine methylation on RPL3 modulates translation elongation for proteostasis maintenance (2021)
  • Author(s): 岩崎信太郎
  • Organizer: 第15回日本臨床ストレス応答学会
  • Invited
• [Presentation] Molecular mechanisms for the initiation of meiosis in mouse germ cells (2021)
  • Author(s): Ayumu Suzuki, Yuka Kitamura, Kousuke Uranishi, Yosuke Mizuno, Masazumi Nishimoto, Akihiko Okuda
  • Organizer: 第44回日本分子生物学会年会
• [Presentation] Molecular motor Myosin Id localize to dendritic spines. (2021)
  • Author(s): Tetsuya Sasaki, Masae Ohtsuka, Suguru Iwata, Yosuke Takei.
  • Organizer: Japanese Association of Anatomists 109th Kanto Branch Academic Meeting.
• [Presentation] Multiscale and multimodal Ca2+ imaging to avoid mereological fallacy in neuroscience. (2021)
  • Author(s): Osanai M
  • Organizer: 第64回日本神経化学会大会
  • Invited
• [Presentation] Mutual regulation between MAPK phosphatases and the ERK pathway (2021)
  • Author(s): Mariko Saitoh, Yuji Kubota, Mutsuhiro Takekawa
  • Organizer: G2 plus Retreat
• [Presentation] Neonatal NMDA receptor blockade and glutamate decarboxylase 67-kDa isoform haplodeficiency synergistically cause behavioral alterations (2021)
  • Author(s): 藤原和之、柿崎利和、柳川右千夫
  • Organizer: 第44回日本神経科学大会
• [Presentation] Novel regulation of RNA granule dynamics by neurodegenerative disease-causing gene products (2021)
  • Author(s): 堀尾朋世, 椎名伸之
  • Organizer: 第44回日本神経科学大会・第1回CJK国際会議 2021年7月
  • Int'l Joint Research
• [Presentation] Novel regulation of RNA granule dynamics by neurodegenerative disease-causing gene products (2021)
  • Author(s): 堀尾朋世, 椎名伸之
  • Organizer: 第44回日本分子生物学会年会
• [Presentation] P2Y1受容体を介したニューロンアストロサイトーミクログリア間情報処理機構 (2021)
  • Author(s): 鈴木秀明、繁冨英治、平山幸歩、高橋由香里、池中一裕、田中謙二、加藤総夫、尾藤晴彦、小泉修一
  • Organizer: 第44回日本神経科学大会・CJK第1回国際会議
  • Int'l Joint Research
• [Presentation] pan-CDK阻害活性を示す新規合成ラメラリン類縁体Azalam 4の細胞特異的なアポトーシス誘導作用 (2021)
  • Author(s): 大橋愛美, 福田勉, 岡村睦美, 西谷直之, 岩尾正倫, 旦慎吾
  • Organizer: 第80回日本癌学会学術総会
• [Presentation] Pathologic findings toward the concept of cancer as ferroptosis-resistance 変革する病理学 : 形態診断から普遍的研究プラットフォームへ (2021)
  • Author(s): 豊國伸哉、Hao Zheng, Yingyi Kong, Yaguang Luo、本岡大社
  • Organizer: 第80回日本癌学会総会(2021年9月30日～10月2日、神奈川県横浜市パシフィコ横浜、ハイブリッド開催)
• [Presentation] Phos-tag電気泳動法を活用したMAPK phosphatase(MKP)とMAPK経路の相互調節機構の解析 (2021)
  • Author(s): 齊藤 まりこ、久保田 裕二、武川 睦寛
  • Organizer: 第72回日本電気泳動学会
• [Presentation] PXR活性化の肝化学発がんへの影響の理解と機序解析 (2021)
  • Author(s): 志津怜太
  • Organizer: 第3回医薬品毒性機序研究会
  • Invited
• [Presentation] RAS下流のエフェクター分子ARL4Cを標的とした膵癌の浸潤転移の制御 (2021)
  • Author(s): 原田昭和, 松本真司, 菊池章
  • Organizer: 第80回日本癌学会学術総会
• [Presentation] Rb1/Trp53遺伝子改変マウスモデルを用いた小細胞肺がんの悪性化における細胞接着分子CADM1の解析 (2021)
  • Author(s): 富永みずき、舩城桐子、坂本毅治、伊東剛、村上善則
  • Organizer: 第80回日本癌学会学術総会
• [Presentation] Regulation of Metabolism by nuclear factors (2021)
  • Author(s): Kazuya Yamagata
  • Organizer: The Quadruple symposium-2021
  • Int'l Joint Research / Invited
• [Presentation] Regulation of thrombin activity by a linear hexaoxazole of G-quadruplex ligand with controlling thrombin-binding aptamer topologies (2021)
  • Author(s): Shogo Sasaki, Yue Ma, Kazunori Ikebukuro, Masayuki Tera, Kazuo Nagasawa
  • Organizer: The 48th International Symposium on Nucleic Acids Chemistry
  • Int'l Joint Research
• [Presentation] Retinoic acid-related orphan receptor-γt overexpression affect the murine central nervous system and behaviors. (2021)
  • Author(s): Tetsuya Sasaki, Aki Takahashi, Hiroko Suzaki, Satoru Takahashi, Yosuke Takei.
  • Organizer: The 64th Annual Meeting of the Japanese Society of Neurochemistry.
• [Presentation] RhoA protects senescence heart by preserving mitochondrial function via Parkin (2021)
  • Author(s): Joanne Ern Chi Soh、清水昭男、Md Rasel Molla、米野雅大、扇田久和
  • Organizer: 日本循環器学会基礎研究フォーラム
• [Presentation] Role of Arc in regulation of surface AMPA receptors and cognition (2021)
  • Author(s): 奥野浩行、石井雄一郎、遠藤俊裕、鈴木祐輔、阿部学、今吉格、掛山正心、崎村建司、尾藤晴彦
  • Organizer: 第44回日本神経科学大会
  • Invited
• [Presentation] Role of ferroptosis in carcinogenesis and tumor biology. AACR-JCA joint symposium on carcinogenesis and DNA damage in memory of Dr. Takashi Sugimura (2021)
  • Author(s): Toyokuni S
  • Organizer: Annual Meeting American Association for Cancer Research (April 10-15 ; May 17-21, 2021 ; virtual ; invited speaker)
  • Int'l Joint Research / Invited
• [Presentation] Role of the locus coeruleus-basolateral amygdalar noradrenergic projection in the retrieval of taste aversion memory in mice : a pharmacological and chemogenetic circuit manipulation study. (2021)
  • Author(s): Iguchi, Y., Fukabori, R., Kato, S., & Kobayashi, K.
  • Organizer: 日本動物心理学会第81回大会
• [Presentation] Roles of G4 binding and multimization of Rifl in S phase regulation in fission yeast cells. (2021)
  • Author(s): Hisao Masai, Yutaka Kanoh, Kaho Takasawa, Daisuke Koida, Seiji Matsumoto
  • Organizer: Cold Spring Harbor Asia Conference YEAST AND LIFE SCIENCES
  • Int'l Joint Research / Invited
• [Presentation] SAPKにより制御されている miRNA-X は大腸癌のアポトーシスを抑制する (2021)
  • Author(s): 渡海 紀子, 中村 貴紀, 武川 睦寛
  • Organizer: 第80回 日本癌学会学術総会
• [Presentation] SAPK-regulated microRNA-X suppresses apoptosis in colorectal cancer (2021)
  • Author(s): 渡海 紀子、中村 貴紀、武川 睦寛
  • Organizer: 第80回日本癌学会学術総会
• [Presentation] Serotonin Brain and beyond. (2021)
  • Author(s): Kae Nakamura
  • Organizer: 筑波大学神経科学先端セミナー
  • Invited
• [Presentation] Sexually different mechanisms of meiotic cell cycle in mammalian germ cells (2021)
  • Author(s): Kei-ichiro Ishiguro
  • Organizer: 44th Annual meeting of Molecular Biology Society of Japan.
  • Invited
• [Presentation] Shati/Nat81 determine the stress sensitivity via regulation of BDNF expression in the striatum. (2021)
  • Author(s): H Miyanishi, S Muramatsu, A Nitta.
  • Organizer: AsCNP (Asian College of Neuropsychopharmacology)
  • Int'l Joint Research
• [Presentation] Shati/Nat81 dettermine the stress sensitivity via regulation of BDNF expression in the striatum (2021)
  • Author(s): Miyanishi H, Muramatsu S, Nitta A.
  • Organizer: Toyama-Basel Meeting
  • Int'l Joint Research / Invited
• [Presentation] Shati/Nat81 dettermine the stress sensitivity via regulation of BDNF expression in the striatum (2021)
  • Author(s): Nitta A, Miyanishi H, Muramatsu S.
  • Organizer: 60th Annual metting of the American College of Neuropsychopharmacology (ACNP)
  • Int'l Joint Research
• [Presentation] Stomatin possesses tumor-suppressive effect via the PDPK1-Akt signaling axis. (2021)
  • Author(s): Nor Idayu A. Rahman、佐藤朗、清水昭男、米野雅大、Md Rasel Molla、Joanne Ern Chi Soh、Le Kim Chi Nguyen、和田晃典、河内明宏、扇田久和
  • Organizer: 日本生化学会近畿支部例会
  • Int'l Joint Research
• [Presentation] STRA8 plays multiple roles in gonadal development and meiotic cell cycle in mouse female germ cells (2021)
  • Author(s): Ryuki Shimada, Kei-ichiro Ishiguro
  • Organizer: International Symposium on the Biology of Vertebrate Sex Determination
  • Int'l Joint Research / Invited
• [Presentation] Targeting G-quadruplex nucleic acids for cancer therapeutics (2021)
  • Author(s): Seimiya H
  • Organizer: 第80回日本癌学会学術総会
  • Invited
• [Presentation] Thalamocortical axons control the cytoarchitecture of neocortical layers by area-specific supply of VGF (2021)
  • Author(s): Haruka Sato
  • Organizer: The International Symposium on Development and PLASTICITY of NEURAL SYSTEMS
  • Int'l Joint Research
• [Presentation] The central circadian clock regulates wakefulness via CRF neurons in the hypothalamus. (2021)
  • Author(s): 小野大輔
  • Organizer: 第44回日本神経科学大会
• [Presentation] The coordination of septin cytoskeleton and actomyosin underlying memory consolidation (2021)
  • Author(s): Ageta-Ishihara N, Kosaka Y, Fujiwara R, Fuse N, Suzuki A, Kinoshita I, Mizukami M, Kinoshita M.
  • Organizer: The 80th Fujihara Seminar “Molecular and cellular mechanisms of brain systems generating individuality”
• [Presentation] The cytoplasmic adaptor FRS2beta fashions a cytokine-rich inflammatory microenvironment that promotes breast cancer carcinogenesis (2021)
  • Author(s): Noriko Gotoh
  • Organizer: American Association for Cancer Research (AACR) Annual Meeting 2021
  • Int'l Joint Research
• [Presentation] The effect of GABA deficiency on embryonic neocortical development (2021)
  • Author(s): Weiru Jiang, Toshikazu Kakizaki, Goichi Miyoshi, Yuchio Yanagawa
  • Organizer: 第44回日本神経科学大会
• [Presentation] The effect of GABA on embryonic neocortical development (2021)
  • Author(s): Weiru Jiang, Toshikazu Kakizaki, Goichi Miyoshi, Masashi Kurachi, Yasuki Ishizaki, Yuchio Yanagawa
  • Organizer: 第68回北関東医学会
• [Presentation] The individual history of reward learning and stress responsibility : resilience induced by contingency learning between action and reward. (2021)
  • Author(s): Iguchi, Y., Hikishima, K., & Kobayashi, K.
  • Organizer: The 43rd Annual Meeting of the Japan Neuroscience Society
• [Presentation] The roles of brain polyunsaturated fatty acids in dopamine-dependent ingestive behaviors (2021)
  • Author(s): Nobuyuki Sakayori, Masanori Katakura, Makoto Sugita, Kazuto Kobayashi
  • Organizer: The 44th Annual Meeting of the Japan Neuroscience Society・The lst CJK International Meeting
  • Int'l Joint Research
• [Presentation] The roles of the polyol pathway in sensing glucose uptake. (2021)
  • Author(s): Sano, H., Nakamura, A., Yamane, M., Niwa, H., Nishimura, T., Araki, K., Takemoto, K., Ishiguro, K., Aoki, H., and Kojima, M.
  • Organizer: 第14回日本ショウジョウバエ研究会
• [Presentation] Time as medicine and disease etiology (2021)
  • Author(s): Masao Doi
  • Organizer: The CFBT Summer Showcase, Manchester, UK
  • Int'l Joint Research / Invited
• [Presentation] Trpsl hypomorph mice show postnatal skeletal dysplasia. (2021)
  • Author(s): Saeki N. and Abe M.
  • Organizer: DevDMM online meeting (September 17, 2021)
  • Int'l Joint Research
• [Presentation] Tumor microenvironment-mediated upregulation of stomatin for suppressing the tumor growth by inhibiting the Akt pathway (2021)
  • Author(s): 扇田久和、佐藤朗
  • Organizer: 日本癌学会学術総会
• [Presentation] T細胞寛容におけるクロマチン制御因子TRIM28の機能解析 (2021)
  • Author(s): 竹馬俊介
  • Organizer: 第29回京都T細胞会議
• [Presentation] Unified synthesis of aplysiatoxin/ocillatoxins, Hawaiian marine natural products (2021)
  • Author(s): Toshio Nishikawa
  • Organizer: The International Chemical Congress of Pacific Basin Societies 2021 (Pacifichem2021)
  • Int'l Joint Research / Invited
• [Presentation] Validation of neural activity measurement by activity-induced manganese-enhanced MRI (2021)
  • Author(s): Osanai M, Hasegawa N, Tanihira H, Kikuta S, Sano H, Kajita Y, Ohshiro T, Nambu A, Homma N, Mushiake H
  • Organizer: 第44回日本神経科学大会
• [Presentation] αSMA-CreERT2 BAC トランスジェニックマウスの作製 (2021)
  • Author(s): 後藤篤史, 河村真吾, 槇利衣, 岩田直也, 蔵満紀成, 中村寛, 永野昭仁, 野澤聡, 松本和, 田口純平, 山田泰広, 秋山治彦
  • Organizer: 第36回 日本整形外科学会基礎学術集会
• [Presentation] アスコルビン酸によるスーパーオキシド消去はSOD1欠損マウスの生存に必須である (2021)
  • Author(s): 本間拓二郎、武田裕司、赤塚慎也、斉藤真一、豊國伸哉、藤井順逸
  • Organizer: 第74回日本酸化ストレス学会・第21回日本NO学会合同学術集会
• [Presentation] アルキニルボレートを鍵中間体とするオキサボロールの高選択的構築 (2021)
  • Author(s): 木村正成, 末吉巽, 小野寺玄, 福田勉
  • Organizer: 第67回有機金属化学討論会
• [Presentation] エネルギー毒性 (2021)
  • Author(s): 石堂正美
  • Organizer: 第94回日本生化学会
  • Invited
• [Presentation] オレキシンとナルコレプシー症状発現メカニズムの最新研究 (2021)
  • Author(s): 山中章弘
  • Organizer: 第12回日本臨床睡眠医学会学術集会
  • Invited
• [Presentation] オレキシン神経活動によるレム睡眠と脱力発作の調節 (2021)
  • Author(s): 山中章弘
  • Organizer: 2021年度生理学研究所研究会 運動・行動から紐解く脳神経回路発達メカニズムの異分野融合研究による解明
  • Invited
• [Presentation] がん細胞の酸性環境適応機構「acid addiction」の分子メカニズム解析 (2021)
  • Author(s): 船戸洋佑、本田茉子、山崎大輔、三木裕明
  • Organizer: 第94回日本生化学会大会
• [Presentation] グアニン四重鎖を安定化する大環状へキサオキサゾールオリゴマーの開発 (2021)
  • Author(s): 大山彩, 佐々木捷悟, 寺正行, 長澤和夫
  • Organizer: 日本化学会第102回春季年会
• [Presentation] グリアーニューロン機能連関のマルチモーダルイメージング (2021)
  • Author(s): 繁冨英治、小泉修一
  • Organizer: 第44回日本神経科学大会・CJK第1回国際会議
  • Int'l Joint Research
• [Presentation] グルタミン酸脱炭酸酵素67kDaアイソフォーム(GAD67)ノックアウトラットが示す恐怖記憶の変化 (2021)
  • Author(s): 藤原和之、佐藤匠、宮坂佳樹、真下知士、柳川右千夫
  • Organizer: 先端モデル動物支援プラットフォーム若手技術講習会2021
  • Invited
• [Presentation] クロモドメインタンパクCdy12は幹細胞の多能性維持に重要である (2021)
  • Author(s): 服部奈緒子、木村佳那、飯田直子、今井俊夫、小泉美帆、本田浩章、牛島俊和
  • Organizer: 第14回日本エピジェネティクス研究会年会
• [Presentation] ジェンダー平等とダイバーシティ推進への日本神経科学会の取り組みとALBAの紹介 (2021)
  • Author(s): 渡部文子
  • Organizer: 第40回日本認知症学会学術集会
  • Invited
• [Presentation] シスプラチン誘発腎障害に対する新規予防候補薬の効果 (2021)
  • Author(s): 吉田 愛美, 合田 光寛, 杉本 祐悟, 八木田 ひかり, 神田 将哉, 吉岡 俊彦, 櫻田 巧, 相澤 風花, 濱野 裕章, 岡田 直人, 八木 健太, 石澤 有紀, 座間味 義人, 石澤 啓介
  • Organizer: 第140回日本薬理学会近畿部会
• [Presentation] シスプラチン誘発腎障害に対する新規予防薬の探索 (2021)
  • Author(s): 吉田 愛美, 合田 光寛, 杉本 祐悟, 八木田 ひかり, 神田 将哉, 吉岡 俊彦, 櫻田 巧, 石澤 有紀, 相澤 風花, 濱野 裕章, 岡田 直人, 八木 健太, 座間味 義人, 石澤 啓介
  • Organizer: 第60回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
• [Presentation] ジペプチジルペプチダーゼIIIが糖尿病性腎臓病を抑制する作用機序 (2021)
  • Author(s): 米野雅大、Md Rasel Molla、清水昭男、扇田久和
  • Organizer: 日本生化学会大会
• [Presentation] チオレドキシンの機能低下は神経細胞とオリゴデンドロサイトの細胞死を惹起する (2021)
  • Author(s): 大守伊織, 大内田守, 今井宏彦, 豊國伸哉, 真下知士
  • Organizer: 第44回日本分子生物学会
• [Presentation] テロメアグアニン四重鎖と選択的に共有結合する光架橋型へキサオキサゾール化合物の開発 (2021)
  • Author(s): 柳田 和輝, 佐々木 捷悟, 馬 悦, 池袋 一典, 寺 正行, 長澤 和夫
  • Organizer: 日本ケミカルバイオロジー学会第15回年会
• [Presentation] テロメアグアニン四重鎖と選択的に共有結合する光架橋型へキサオキサゾール化合物の開発 (2021)
  • Author(s): 柳田 和輝, 佐々木 捷悟, 馬 悦, 池袋 一典, 寺 正行, 長澤 和夫
  • Organizer: 日本化学会第102回春季年会
• [Presentation] ドーパミン受容体アンタゴニストの受容体非依存的なフォーカス形成抑制能 (2021)
  • Author(s): 青山 愛、藤元次郎、平野弘之、渡辺信元、長田裕之、仙波憲太郎
  • Organizer: 第80回日本癌学会学術総会
• [Presentation] トラウマ記憶の制御基盤の解明とPTSD治療方法開発への応用 (2021)
  • Author(s): 喜田 聡
  • Organizer: 生体機能と創薬シンポジウム2021
  • Invited
• [Presentation] ニューロンーグリア間情報伝達の可視化 (2021)
  • Author(s): 繁冨英治、小泉修一
  • Organizer: 第64回日本神経化学会大会
• [Presentation] パーキンソン疾患治療薬シード化合物のケミカルバイオロジー (2021)
  • Author(s): 井本正哉
  • Organizer: 第94回日本生化学会大会
  • Invited
• [Presentation] パイロトーシス抑制剤の探索 (2021)
  • Author(s): 中村萌香, 神﨑香穂, 是枝杏佳, 杉山拓朗, 福田勉, 石橋郁人, 川﨑則彦, 石原淳, 武田弘資
  • Organizer: 令和3年度日本生化学会九州支部例会
• [Presentation] フェロトーシス抵抗性と発がん (2021)
  • Author(s): 豊國伸哉
  • Organizer: 日本酸化ストレス学会シンポジウム1 : フェロトーシス-脂質過酸化がもたらす細胞死 第74回日本酸化ストレス学会第21回日本NO学会合同集会(2021年5月19日～20日、Live-Web開催)
  • Invited
• [Presentation] フェロトーシス抵抗性と発がん (2021)
  • Author(s): 豊國伸哉
  • Organizer: 第21回日本抗加齢医学会 会長企画シンポジウム5 : メタロミクスと抗加齢医学(2021年6月25日～6月27日、Live-Web開催)
  • Invited
• [Presentation] フェロトーシス抵抗性と発がん (2021)
  • Author(s): 豊國伸哉
  • Organizer: 第29回日本Cell Death学会 シンポジウムIII : フェロトーシス研究の最前線(2021年7月26日～27日、Web開催)
  • Invited
• [Presentation] フォルミン蛋白質Fhod3による大脳皮質錐体細胞の樹状突起スパインの形態制御 (2021)
  • Author(s): Hikmawan Wahyu Sulistomo、根本隆行、鹿毛陽子、藤井 哉、尾藤晴彦、武谷 立
  • Organizer: 第94回日本生化学会
• [Presentation] ペリサイト選択的ATP感受性カリウムチャネルによる中枢特異的な血管平滑筋細胞分化制御メカニズムの解明 (2021)
  • Author(s): 安藤 康史
  • Organizer: 第29回日本血管生物医学会学術集会
• [Presentation] ベンゾフラン骨格を有する糸状菌由来天然物fumimycinおよびlentofuranineの生合成研究 (2021)
  • Author(s): 南歩実、岸本真治、渡辺賢二
  • Organizer: 第23回天然薬物の開発と応用シンポジウム
• [Presentation] ホスフィンーボラン配位子と金触媒によるマロン酸エステル誘導体のConia-Ene反応 (2021)
  • Author(s): 小野寺玄, 桑原麟太郎, 福田勉, Norbert Krause, 木村正成
  • Organizer: 第67回有機金属化学討論会
• [Presentation] マウス海馬における Teneurin-4 発現減少によるうつ様行動の誘導 Decreased expression of Teneurin-4 in mouse hippocampus induces depressive-like behavior (2021)
  • Author(s): 杉森 祐一朗、浅野 昂志、泉尾 直孝、村松 慎一、新田 淳美
  • Organizer: 第95回日本薬理学会
• [Presentation] マウス線条体におけるShati/Nat8-BDNF経路1によるストレス感受性制御 (2021)
  • Author(s): 宮西肇、村松慎一、新田淳美
  • Organizer: 第43回日本生物学的精神医学会・第51回日本神経精神薬理学会合同年会
• [Presentation] マウス前頭前皮質CB1受容体の認知記憶への関与 (2021)
  • Author(s): 徳竹伯洸, 浅野昴志, 泉尾直孝, 新田淳美.
  • Organizer: 2021年度アルコール・薬物依存関連学会合同学術総会
• [Presentation] マウス前頭前皮質CB1受容体の認知機能への関与 (2021)
  • Author(s): 徳竹 伯洸、浅野 昂志、泉尾 直孝、新田 淳美
  • Organizer: 第95回日本薬理学会
• [Presentation] マウス膵島が産生するGABAの主要合成酵素の解明 (2021)
  • Author(s): 日比健人、若松馨、柳川右千夫、中川祐子、藤谷与士夫、宮田茂雄
  • Organizer: 第68回北関東医学会
• [Presentation] メタンフェタミン誘発性依存に対するオステオポンチンの発現上昇を介したグラチラマー酢酸塩の抑制効果 Suppressive effects of glatiramer acetate on the addiction induced by methamphetamine via upregulation of osteopontin in mice (2021)
  • Author(s): 玉谷 隆典、泉尾 直孝、中島 卓海、新田 淳美
  • Organizer: 第95回日本薬理学会
• [Presentation] ラマン分光法を用いた神経活動の非侵襲な評価技術の開発 (2021)
  • Author(s): 赤木祐香、髙山祐三、木田泰之
  • Organizer: 第44回日本分子生物学会年会
• [Presentation] リボソームプロファイリングのコツ (2021)
  • Author(s): 岩崎信太郎
  • Organizer: イルミナウェブセミナープロフェッショナルシリーズ
  • Invited
• [Presentation] レトロトランスポゾンLINE-1転移モニターマウスの作製 (2021)
  • Author(s): 藤飯愼也、村田唯、文東美紀、仲地ゆたか、荒木喜美、岩本和也
  • Organizer: 第44回日本分子生物学会
• [Presentation] ワークショップ : NAD依存性酵素の高次生体機能調節機構-エネルギー代謝を超えて- SIRT7による加齢関連疾患の発症制御 (2021)
  • Author(s): 山縣和也
  • Organizer: 第44回日本分子生物学会年会
  • Invited
• [Presentation] 遺伝子多型から実現する緩和ケア診療最適化 (2021)
  • Author(s): 住谷昌彦
  • Organizer: 第43回日本疼痛学会
  • Invited
• [Presentation] 栄養・食糧研究分野において齧歯類を用いた脳科学的手法を活用する 一定量的な行動解析・形態解析を行うには? (2021)
  • Author(s): 喜田 聡
  • Organizer: 第75回日本栄養・食糧学会大会
  • Invited
• [Presentation] 栄養不足による脳内炎症を介した記憶障害機構とその改善方法の開発 (2021)
  • Author(s): 喜田 聡
  • Organizer: レドックスR&D戦略委員会第1回企画シンポジウム「翻訳・アミノ酸代謝調節による生体機能制御」
  • Invited
• [Presentation] 核小体ストレス応答による小児腫瘍の新たな治療戦略 (2021)
  • Author(s): 河原 康一、中川 俊輔、岡本 康裕、古川 龍彦
  • Organizer: 第59回日本癌治療学会学術集会
• [Presentation] 核内受容体を介した肝化学発がん : リスク評価に向けた機序と種差の理解 (2021)
  • Author(s): 志津怜太
  • Organizer: 第48会日本毒性学会学術年会
  • Invited
• [Presentation] 覚せい剤メタンフェタミンのマウス行動学的変化に対するプレシナプスタンパク質Piccoloの作用. (2021)
  • Author(s): 楠井優香, 宇野恭介, 泉尾直孝, 村松慎一, 新田淳美
  • Organizer: 第43回日本生物学的精神医学会・第51回日本神経精神薬理学会合同年会
  • Invited
• [Presentation] 覚醒剤メタンフェタミンの依存性および毒性への抑制分子群 (2021)
  • Author(s): 新田淳美
  • Organizer: 第64回日本神経化学大会
• [Presentation] 顎顔面形成不全を伴う希少疾患における矯正歯科治療の役割 (2021)
  • Author(s): 黒坂 寛
  • Organizer: 第80回日本矯正歯科学会学術大会&第5回国際会議
  • Int'l Joint Research / Invited
• [Presentation] 幹細胞のエピゲノム記憶に関わるヒストンリーダーの同定 (2021)
  • Author(s): 服部奈緒子、Liu Yu-Yu, 木村佳那、小泉美帆、本田浩章、牛島俊和
  • Organizer: 第44回日本分子生物学会
• [Presentation] 癌抑制遺伝子P53を活性化する核小体ストレス応答による癌治療感受性の制御 (2021)
  • Author(s): 河原 康一、川畑拓斗、古川 龍彦
  • Organizer: 第44回日本分子生物学会年会
• [Presentation] 記憶の長期化に寄与するスパイン内小胞体の役割 (2021)
  • Author(s): 上田(石原)奈津実, 木下専
  • Organizer: 第19回神経科学研究会
  • Invited
• [Presentation] 恐怖記憶の制御基盤の解明とPTSD治療方法開発への応用 (2021)
  • Author(s): 喜田 聡
  • Organizer: 第43回日本生物学的精神医学会・第51回日本神経精神薬理学会 合同年会
• [Presentation] 恐怖記憶制御基盤の解明とPTSD治療方法への応用 (2021)
  • Author(s): 喜田 聡
  • Organizer: 第13回不安症学会学術大会
  • Invited
• [Presentation] 極微細蛍光内視鏡イメージングシステムによるマウス両側海馬CA1 Ca2+イメージング (2021)
  • Author(s): 川淵公美子, 大川宜昭, 瀬戸川将, 斎藤喜人, 増崎紘平, 小山内実
  • Organizer: 第113回近畿生理学談話会
• [Presentation] 苦味物質はROCKシグナリングを増強させ好中球遊走を促進する (2021)
  • Author(s): 小林 大地, 渡井 友也, 小澤 まどか, 神田 泰洋, 雑賀 史浩, 木口 倫一, 松崎 伸介, 片貝 智哉
  • Organizer: 第44回日本分子生物学会
• [Presentation] 減数分裂の開始機構 (2021)
  • Author(s): 石黒啓一郎
  • Organizer: 第39回日本受精着床学会
  • Invited
• [Presentation] 減数分裂開始の性差 (2021)
  • Author(s): 石黒啓一郎
  • Organizer: 第93回日本遺伝学会大会 ワークショップ「非ゲノム情報複製機構による生命現象の制御」
  • Int'l Joint Research / Invited
• [Presentation] 巧いオピオイド・マネジメント (2021)
  • Author(s): 住谷昌彦
  • Organizer: 第55回日本ペインクリニック学会
  • Invited
• [Presentation] 抗癌剤の治療感受性を左右する核小体ストレス応答機構の解明 (2021)
  • Author(s): 河原 康一、古川 龍彦
  • Organizer: 第80回日本癌学会学術総会
• [Presentation] 抗体薬抵抗性子宮体部漿液性がん腹膜播種に対する標的アルファ線治療 (2021)
  • Author(s): 李 惠子、安康真由香、長谷川 純崇
  • Organizer: 日本放射線影響学会第64回大会
• [Presentation] 構造活性相関を指向した3次元構造を有するリコポジウムアルカロイドの全合成 (2021)
  • Author(s): 塚野千尋
  • Organizer: 第5回 京都大学 農学-化学研究所 研究交流会
  • Invited
• [Presentation] 高い抗がん選択性を持つ新規合成ラメラリン類縁体 Azalam 4 の抗がん作用様式の解析 (2021)
  • Author(s): 大橋愛美, 福田勉, 岡村睦美, 西谷直之, 岩尾正倫, 旦慎吾
  • Organizer: 第25回日本がん分子標的治療学会学術集会
• [Presentation] 高脂肪食摂取加齢マウスにおける亜鉛の長期間投与が学習・記憶能に及ぼす影響 (2021)
  • Author(s): 吉田 香, 魏 民, 藤岡正喜, 吉田 泉, 寺本 勲
  • Organizer: 第38回 日本微量栄養素学会学術集会
• [Presentation] 骨肉腫に対する MEK 阻害療法の検証 (2021)
  • Author(s): 木村 聖美、杉原 英志、山口 さやか、信末 博行、サンペトラ、オルテア、大槻 雄士、武藤 章弘、佐谷 秀行、清水 孝恒
  • Organizer: 第80回日本癌学会学術総会
  • Int'l Joint Research
• [Presentation] 骨肉腫に対するMEK阻害療法の検証 (2021)
  • Author(s): 清水孝恒、木村聖美、武藤章弘、佐谷秀行
  • Organizer: 第53回日本臨床分子形態学会総会・学術集会
  • Int'l Joint Research
• [Presentation] 鎖状型ヘキサオキサゾールを用いたグアニン四重鎖のトポロジー変化による結合タンパク質の活性制御 (2021)
  • Author(s): 佐々木 捷悟、馬 悦、寺 正行、長澤 和夫
  • Organizer: 日本ケミカルバイオロジー学会 第15回年会
• [Presentation] 最長寿齧歯類ハダカデバネズミにおける炎症抑制と発がん耐性の連関 (2021)
  • Author(s): 岡香織
  • Organizer: 第42回日本基礎老化学会シンポジウム
  • Invited
• [Presentation] 細胞の″大きさ″を調節する仕組みから紐解く疾患の新しい理解 (2021)
  • Author(s): 山本一男
  • Organizer: 第44回日本分子生物学会年会
• [Presentation] 細胞の生き死にを決定するアナログ -デジタル変換システムの解明 (2021)
  • Author(s): 森泉 寿士、中村 貴紀、曺永 旻、河西 通、武田 洋幸、鈴木 貴、武川 睦寛
  • Organizer: 第73回日本細胞生物学会大会
• [Presentation] 細胞接着分子CADM1は小細胞肺がんの増殖及び転移を促進する (2021)
  • Author(s): 伊東剛、舩城桐子、種井善一、仁木利郎、松原大祐、村上善則
  • Organizer: 第30回日本がん転移学会学術集会
• [Presentation] 子宮体部漿液性がん腹膜播種に対する標的アルファ線治療の前臨床研究 (2021)
  • Author(s): 李 惠子、安康真由香、長谷川 純崇
  • Organizer: 第61回日本核医学会学術総会
• [Presentation] 糸状菌Aspergillus lentulusの生産する新規天然物lentopeptin類の単離、構造決定および生合成 (2021)
  • Author(s): 松原有也、岸本真治、渡辺賢二
  • Organizer: 第23回天然薬物の開発と応用シンポジウム
• [Presentation] 視交叉上核による日内休眠調節メカニズム (2021)
  • Author(s): 小野大輔
  • Organizer: SCNサロン
  • Invited
• [Presentation] 視床下部の特定神経細胞の運命操作、活動操作を用いた睡眠覚醒調節機構の解明 (2021)
  • Author(s): 山中章弘
  • Organizer: 第68回日本実験動物学会総会 学術集会委員会シンポジウム
  • Invited
• [Presentation] 視床下部神経による睡眠覚醒と記憶の制御 (2021)
  • Author(s): 山中章弘
  • Organizer: 千葉不眠症Web講演会
  • Invited
• [Presentation] 軟骨細胞におけるSox9遺伝子のエンハンサー領域の同定と機能解析 (2021)
  • Author(s): 小林 紗知, 波多 賢二, 高畑 佳史, 村上 智彦, 西村 理行
  • Organizer: 第39回日本骨代謝学会学術集会
• [Presentation] 上皮形態形成研究を基盤とした新規抗がん剤開発 (2021)
  • Author(s): 菊池章
  • Organizer: 第51回日本膵臓学会大会
  • Invited
• [Presentation] 情動価値の生成と変容を支える神経回路メカニズム (2021)
  • Author(s): 渡部文子
  • Organizer: 第20回日本生理学会若手の会 サマースクール(ウインタースクール)
  • Invited
• [Presentation] 情動記憶の形成を支える神経回路メカニズム (2021)
  • Author(s): 渡部文子
  • Organizer: 第44回日本神経科学大会
  • Invited
• [Presentation] 物質依存に対するKey分子の発見 (2021)
  • Author(s): 新田淳美
  • Organizer: 生理学研究所研究会2021「多様な視点から情動を捉え直す」
  • Invited
• [Presentation] 神経活動操作を用いた睡眠覚醒と記憶の制御機構の解明 (2021)
  • Author(s): 山中章弘
  • Organizer: 第145回日本薬理学会関東部会
  • Invited
• [Presentation] 神経系におけるLINE-1の機能と精神疾患 (2021)
  • Author(s): 岩本和也
  • Organizer: 第5回転移因子研究会(遺伝研研究会)
• [Presentation] 睡眠覚醒調節におけるオレキシンの役割について (2021)
  • Author(s): 山中章弘
  • Organizer: 不眠症Web講演会
  • Invited
• [Presentation] 睡眠覚醒調節におけるオレキシンの役割について (2021)
  • Author(s): 山中章弘
  • Organizer: 第49回日本頭痛学会総会
  • Invited
• [Presentation] 髄芽腫におけるGLI3 発現および役割 -完結編- (2021)
  • Author(s): 棗田 学、宮原弘明、吉村淳一、塚本佳広、大石誠、Charles G、Eberhart、柿田明美、藤井幸彦
  • Organizer: 第39回日本脳腫瘍病理学会
• [Presentation] 生殖細胞における体細胞分裂から減数分裂への切り替え機構と性差 (2021)
  • Author(s): 石黒啓一郎
  • Organizer: 第126回日本解剖学会総会
  • Invited
• [Presentation] 生殖巣特異的GATA4欠損マウスの作製と胚盤胞補完法に用いる受容胚としての適用性の検討 (2021)
  • Author(s): 岩崎亜美・村田康輔・川村名子・中務 胞・阿部 学・夏目里恵・杉村智史・﨑村建司・山城秀昭
  • Organizer: 第114回 日本繁殖生物学会
• [Presentation] 生理的体温変化による体内時計のパラメトリック制御 Parametric entrainment of the circadian clock by body temperature change (2021)
  • Author(s): 三宅崇仁、井ノ上雄一、土居雅夫
  • Organizer: 第59回日本生物物理学会年会
• [Presentation] 染色体の終わりから始まるがん創薬 (2021)
  • Author(s): 清宮啓之
  • Organizer: 日本遺伝学会市民公開講座
  • Invited
• [Presentation] 線条体間接路ニューロンの応答特性へのD2受容体活性化の影響 (2021)
  • Author(s): 末岡知己, 田村篤史, 稲垣 良, 小林和人, 小山内実
  • Organizer: 第113回近畿生理学談話会
• [Presentation] 線条体投射ニューロンの小胞体依存的なカルシウム振動 (2021)
  • Author(s): 田村 篤史, 小林 和人, 小山内 実
  • Organizer: 2021年度 先端モデル動物支援プラットフォーム若手技術講習会
• [Presentation] 全身性エリテマトーデス、皮膚筋炎、自己免疫水泡症における協調したレトロトランスポゾンとⅠ型IFN経路の特徴 (2021)
  • Author(s): 栗山 裕子、清水 晶、金井 早紀、及川 大輔、徳永 文稔、石川 治、茂木 精一郎
  • Organizer: 第68回北関東医学会総会
• [Presentation] 他個体の社会的敗北ストレスの観察はコカインに対する欲求を増大させる (2021)
  • Author(s): 本野芽衣、齋藤惇、乙田篤輝、張たん、江崎博仁、李雪婷、西谷直也、出山諭司、金田勝幸
  • Organizer: 生体機能と創薬シンポジウム2021
• [Presentation] 他個体の社会的敗北ストレスの観察はコカインに対する欲求を増大させる (2021)
  • Author(s): 本野芽衣、齋藤惇、乙田篤輝、張たん、江崎博仁、李雪婷、西谷直也、出山諭司、金田勝幸
  • Organizer: 次世代を担う若手のための創薬・医療薬理シンポジウム2021
• [Presentation] 多段階皮膚発がんマウスモデルを用いたがん修飾因子の同定 (2021)
  • Author(s): 奥村和弘
  • Organizer: 第68回日本実験動物学会総会
  • Invited
• [Presentation] 大腸菌の第二の複製経路から明らかになる 複製様式の多様性と普遍性 (2021)
  • Author(s): 正井久雄、田中卓、深津理乃、鷺朋子
  • Organizer: 日本遺伝学会 第93回大会
  • Invited
• [Presentation] 中枢神経系におけるヒストン脱メチル化酵素JMJD1Aを介した環境適応機構の解明 (2021)
  • Author(s): 清水 佑一、寒河江 陽菜、荒井 誠、張 吉、関根 伶生、内田 あおい、伊藤 亮、松村 欣宏、酒井 寿郎
  • Organizer: 第44回分子生物学会年会
• [Presentation] 中枢神経系におけるヒストン脱メチル化酵素を介した環境適応機構の解明 (2021)
  • Author(s): 清水 佑一、寒河江 陽菜、荒井 誠、張 吉、関根 伶生、内田 あおい、伊藤 亮、松村 欣宏、酒井 寿郎
  • Organizer: 第44回分子生物学会年会
• [Presentation] 直鎖状ポリユビキチン鎖デコーダーZnUBPのNF-・Bシグナル制御機構の解明 (2021)
  • Author(s): 岩崎 誠、長尾 和哉、及川 大輔、小迫 英尊、徳永 文稔、高橋 宏隆、澤崎 達也
  • Organizer: 第44回日本分子生物学会年会
• [Presentation] 直鎖状ユビキチン修飾を介した炎症・免疫応答制御機構の研究 (2021)
  • Author(s): 及川大輔
  • Organizer: 第67回日本生化学会近畿支部例会
  • Invited
• [Presentation] 痛みなくがん治療を受けるコツ (2021)
  • Author(s): 住谷昌彦
  • Organizer: 2021年度都医学研第4回都民講座
  • Invited
• [Presentation] 転写因子Npas4による低分子量Gタンパク質Gemの発現誘導は神経活動依存的な虚血耐性を引き起こす (2021)
  • Author(s): 高橋 弘雄, 松井 健, 森 英一朗, 山本 融, 坪井 昭夫
  • Organizer: 第44回日本神経科学大会
• [Presentation] 当科で経験した精巣捻転症8例の検討 (2021)
  • Author(s): 形見祐人、藤井喬之、田中彩、下野隆一、久保裕之
  • Organizer: 第60回日本小児外科学会中国四国地方会
• [Presentation] 統合失調症の認知機能障害を改善するエピゲノム治療薬・治療法の探索 (2021)
  • Author(s): 福田 茉由、向井 淳
  • Organizer: 日本薬理学会
• [Presentation] 動物モデルから理解する心的外傷後ストレス障害とその治療方法 (2021)
  • Author(s): 喜田 聡
  • Organizer: 第20回日本トラウマティック・ストレス学会
• [Presentation] 特異なベンゾフラン骨格を有する糸状菌由来天然物の生合成研究 (2021)
  • Author(s): 南歩実、岸本真治、渡辺賢二
  • Organizer: 日本生薬学会第67回年会
• [Presentation] 軟骨細胞におけるSox9遺伝子の発現制御機構の解明 (2021)
  • Author(s): 小林 紗知, 波多 賢二, 高畑 佳史, 村上 智彦, 高野 洋志, 八尾良司, 鵜澤 成一, 西村 理行
  • Organizer: 第6回日本骨免疫学会
• [Presentation] 軟骨細胞の細胞極性を制御する新たな分子メカニズムとその破綻による骨格形成への影響 (2021)
  • Author(s): 菊池 浩二, 中川 真美, 藤森 俊彦, 石黒 啓一郎, 荒木 喜美, 中村 輝, 鈴木 誠, 中西 宏之
  • Organizer: 第94回日本生化学大会
  • Invited
• [Presentation] 軟骨細胞の細胞極性を制御する新たな分子メカニズムとその破綻による骨格形成への影響 (2021)
  • Author(s): 菊池 浩二、中川 真美、藤森 俊彦、石黒 啓一郎、荒木 喜美、中村 輝、鈴木 誠、中西 宏之
  • Organizer: 日本発生生物学会第54回大会
• [Presentation] 二次代謝における酵素反応と非酵素反応 (2021)
  • Author(s): 岸本真治
  • Organizer: 日本生薬学会第67回年会
  • Invited
• [Presentation] 乳がんを発症させるサイトカイン豊富な炎症性微小環境は、膜結合アダプターFRS2betaによって構築される (2021)
  • Author(s): 後藤典子
  • Organizer: 第44回日本分子生物学会年会
  • Invited
• [Presentation] 妊娠中に摂取する多価不飽和脂肪酸の偏りは仔において快楽的摂食を促す (2021)
  • Author(s): 酒寄信幸、片倉賢紀、杉田誠、小林和人
  • Organizer: 第75回日本栄養・食糧学会大会
• [Presentation] 熱ショック誘導性ストレス顆粒形成を担う新規コアタンパク質の同定 (2021)
  • Author(s): 松田碧
  • Organizer: 日本電気泳動学会
• [Presentation] 熱ショック誘導性ストレス顆粒形成を担う新規コアタンパク質の同定 (2021)
  • Author(s): 松田碧
  • Organizer: 日本分子生物学会
• [Presentation] 熱ショック誘導性ストレス顆粒形成を担う新規コアタンパク質の同定 (2021)
  • Author(s): 松田 碧, 中村 貴紀, 小迫 英尊, 武川 睦寛
  • Organizer: 第44回日本分子生物学会年会
• [Presentation] 脳の発生・発達における必須脂肪酸の役割 (2021)
  • Author(s): 酒寄信幸
  • Organizer: 日本脂質栄養学会第30回大会
  • Invited
• [Presentation] 脳機能イメージングのための極微細蛍光内視鏡イメージングシステムの改良 (2021)
  • Author(s): 増﨑紘平, 川淵公美子, 廣瀬くるみ, 田村篤史, 小山内実
  • Organizer: 第113回近畿生理学談話会
• [Presentation] 脳機能発現メカニズムの解明を目指したマルチスケールイメージングシステム (2021)
  • Author(s): 小山内実, 川淵公美子, 末岡知己, 増﨑紘平, 松下知佳, 上村 優輝, 田村篤史
  • Organizer: 第113回近畿生理学談話会
• [Presentation] 脳神経系における体細胞変異と精神疾患 (2021)
  • Author(s): 岩本和也
  • Organizer: 第66回日本人類遺伝学会
  • Invited
• [Presentation] 背側線条体におけるShati/Nat81によるストレス感受性の制御メカニズム Regulatory mechanism of stress sensitivity by Shati/Nat81 in the dorsal striatum (2021)
  • Author(s): 宮西 肇、村松 慎一、新田 淳美
  • Organizer: 第95回日本薬理学会
• [Presentation] 発癌ストレスによって誘導されるSAPK経路活性化の分子機構と生理的意義の解析(ポスター発表) (2021)
  • Author(s): 川瀧紗英子
  • Organizer: 第44回分子生物学会年会
• [Presentation] 微小な温度変化がもたらすmRNA翻訳速度調節と概日時計制御 (2021)
  • Author(s): 三宅崇仁、井ノ上雄一、土居雅夫
  • Organizer: Biothermology Workshop - 2021's Annual Workshop
• [Presentation] 病原性アスペルギルス属真菌が産生する免疫抑制化合物sphingofungin類の生合成機構の解明 (2021)
  • Author(s): 永井拓実、岸本真治、渡辺賢二
  • Organizer: 第23回天然薬物の開発と応用シンポジウム
• [Presentation] 腹側被蓋野にチロシン水酸化酵素野生型あるいはS40E変異体を過剰発現させたマウスにおける生化学的および行動学的変化. (2021)
  • Author(s): 志村武信, 名古-岩下由佳, 森屋由紀, 村松慎一, 原怜, 井手聡一郎, 池田和隆, 一瀬宏
  • Organizer: 第64回日本神経化学会大会
• [Presentation] 翻訳速度制御を介した体内時計のパラメトリック制御 Parametric entrainment of the circadian clock via altering translational velocity (2021)
  • Author(s): 三宅崇仁、井ノ上雄一、土居雅夫
  • Organizer: 第44回日本分子生物学会年会
• [Presentation] 慢性の抗利尿ホルモン不適切分泌症候群(SIADH)マウスモデルにおけるバソプレシンエスケープと記憶障害 (2021)
  • Author(s): 藤沢治樹、中山将吾、川上司、上野慎士、淺田陽平、戸松瑛介、吉野寧維、平塚いづみ、清野祐介、四馬田恵、高柳武志、椙村益久、鈴木敦詞
  • Organizer: 第94回日本内分泌学会学術総会
• [Presentation] 慢性腎臓病を伴う早発老化モデル動物の発見 (2021)
  • Author(s): 大内田守, 大守伊織, 今井宏彦, 豊國伸哉, 真下知士
  • Organizer: 第44回日本分子生物学会
• [Presentation] 葉緑体翻訳と細胞質mRNA調節のシンクロナイゼーション (2021)
  • Author(s): 岩崎信太郎
  • Organizer: 2021年度ラン藻ゲノム交流会
  • Invited
• [Presentation] 抑制性シナプス抑制因子MDGA1のヘミ欠損は海馬LTPの低下と学習・記憶異常を引き起こすが、サイクロセリンの急性投与により回復する (2021)
  • Author(s): 山本 融, 尾嶋 大喜, 多田 篤史, 田之上 優, 黒川 直弘, 窪田 剛志, 高橋 弘雄, 岸本 泰司, 冨永 貴志
  • Organizer: 第44回日本神経科学大会
• [Presentation] 腕傍核-視床下部経路による嫌悪学習と摂食行動の制御 (2021)
  • Author(s): 永嶋宇、永瀬将志、三上香織、遠山卓、森島美絵子、渡部文子
  • Organizer: 第44回日本神経科学大会
• [Presentation] 胚盤胞補完法とES細胞を用いた甲状腺再生 (2021)
  • Author(s): 冉慶松, 周啓亮, 小田加奈子, 泰江彰浩, 阿部学, 笹岡俊邦, 崎村健司, 味岡洋一, 西條康夫
  • Organizer: 第20回日本再生医療学会総会
• [Presentation] 頸部リンパ節摘出による脳梗塞病態への減弱効果 Suppressive effects of cervical lymph nodes excision on pathology of ischemic cerebral stroke (2021)
  • Author(s): 高橋 晃、泉尾 直孝、浅野 昂志、新田 淳美
  • Organizer: 第95回日本薬理学会
• [Presentation] 齧歯類および霊長類におけるグルタミン酸受容体GluD2の小脳外局在 (2021)
  • Author(s): 今野幸太郎、山崎美和子、渡辺雅彦
  • Organizer: 解剖学会 第67回 東北・北海道連合支部学術集会
• [Book] ダイソームプロファイリング法によるリボソーム衝突の網羅探索 (2022)
  • Author(s): 岩崎信太郎
  • Total Pages: 149
  • Publisher: 生化学
• [Book] 減数分裂開始の分子機構 Hormone Frontier in Gynecologyメディカルレビュー社 (2022)
  • Author(s): 石黒啓一郎
  • Total Pages: 75
  • Publisher: メディカルレビュー社
• [Book] “Design, Concise Synthesis and Self-Assembly of the Mid-Sized Molecules Exploiting Bispyrrolidinoindoline Alkaloidal Scaffolds” In Middle Molecular Strategy : Flow Synthesis to Functional Molecules (2021)
  • Author(s): Hiroki Oguri
  • Total Pages: 367
  • Publisher: Springer.
• [Book] BIO Clinica 5月号 疾患ゲノム研究の最前線36(5) ゲノムデータベースに眠る生殖細胞関連 遺伝子の同定とその疾患モデル動物の解析 (2021)
  • Author(s): 丹野修宏, 竹本一政, 高田幸, 石黒啓一郎
  • Total Pages: 120
  • Publisher: 北隆館
• [Book] Optogenetics. Advances in Experimental Medicine and Biology (2021)
  • Author(s): Osanai, M., Miwa, H., Tamura, A., Kikuta, S., Iguchi, Y., Yanagawa, Y., Kobayashi, K., Katayama, N., Tanaka, T., & Mushiake, H.
  • Total Pages: 648
  • Publisher: Springer Nature Singapore Pte Ltd.
• [Book] Precision Medicine 7月臨時増刊号4(8)「シングルセル解析の新たな可能性」 精巣の減数第一分裂でエピゲノムの解消に働くZFP541-KCTD19転写抑制複合体 (2021)
  • Author(s): 石黒啓一郎, 高田幸, 島田龍輝, 竹本一政, 小寺千郷, 丹野修宏, 江嵜綾乃, 荒木喜美
  • Total Pages: 104
  • Publisher: 北隆館
• [Book] 時間生物学と医療の融合-現状と将来- (2021)
  • Author(s): 土居雅夫
  • Total Pages: 52
  • Publisher: Medical Science Digest
• [Book] 実験医学 増刊 「相分離~メカニズムと疾患~」 ストレス顆粒形成による生命機能制御と疾患 (2021)
  • Author(s): 吉岡 大介、中村 貴紀、武川 睦寛
  • Total Pages: 223
  • Publisher: 羊土社
• [Book] 薬剤耐性胃がん細胞のがん幹細胞性とその生存分子経路(がん微小環境に1細胞レベルで挑む) (2021)
  • Author(s): 馬島哲夫, 清宮啓之
  • Total Pages: 220
  • Publisher: 羊土社
• [Book] 老化と体内時計 : 加齢による脳内中枢時計の機能低下を中心に老年医学 2021年7月号 (2021)
  • Author(s): 濵田悠貴、山口賀章、土居雅夫
  • Total Pages: 100
  • Publisher: Geriatric Medicine(老年医学)
• [Remarks] 先端モデル動物支援プラットフォーム(AdAMS)ホームページ
  • URL: http://model.umin.jp/
• [Remarks] 北海道大学大学院薬学研究院生化学研究室ホームページ
  • URL: http://www.pharm.hokudai.ac.jp/seika/index.html
• [Remarks] 北海道大学遺伝子病制御研究所分子腫瘍分野ホームページ
  • URL: http://www.igm.hokudai.ac.jp/oncology/
• [Remarks] 東北大学 大学院医学系研究科 医化学分野ホームページ
  • URL: http://www.dmbc.med.tohoku.ac.jp/official/index.html
• [Remarks] 東北大学大学院薬学系研究科薬理学分野ホームページ
  • URL: http://www.pharm.tohoku.ac.jp/~yakuri/yakuri_top.html
• [Remarks] 福島県立医科大学研究成果情報ページ
  • URL: https://www.fmu.ac.jp/univ/kenkyuseika/research/1709.html
• [Remarks] 筑波大学 医学医療系 生命医科学域 解剖学・神経科学研究室
  • URL: http://www.kansei.tsukuba.ac.jp/~takeilab/
• [Remarks] 筑波大学プレスリリース「血液中のインターロイキン17A過剰は脳のミクログリア活性を低下させる～ASDなど精神・神経系疾患治療への道標～」
  • URL: https://research-er.jp/articles/view/96508
• [Remarks] 筑波大学ホームページ TSUKUBA JOURNAL
  • URL: https://www.tsukuba.ac.jp/journal/index.html
• [Remarks] 医療NEWSホームページ 筑波大学「血中IL-17Aの恒常的過剰が中枢神経系に与える影響をマウスで解析」
  • URL: http://www.qlifepro.com/news/20210216/serum-i117a.html
• [Remarks] 筑波大学 Research News Mimicking a Chronic Immune Response Changes the Brain
  • URL: https://www.tsukuba.ac.jp/en/research-news/20210212140000.html
• [Remarks] 理化学研究所RNAシステム生化学研究室 岩崎研究室ホームページ
  • URL: http://iwasakirna.com/
• [Remarks] 理化学研究所RNAシステム生化学研究室 岩崎研究室ホームページ
  • URL: http://www.riken.jp/research/labs/chief/rna_sys_biochem/
• [Remarks] 学術変革領域Bパラメトリク翻訳ホームページ
  • URL: http://parametric-translation.pharm.kyoto-u.ac.jp
• [Remarks] 千葉大学大学院医学研究院 内分泌代謝・血液・老年内科学ホームページ
  • URL: https://www.m.chiba-u.ac.jp/dept/clin-cellbiol/research/diabetic/study_05/
• [Remarks] 千葉大学大学院医学研究院 内分泌代謝・血液・老年内科学ホームページ
  • URL: https://www.m.chiba-u.ac.jp/dept/clin-cellbiol/research/diabetic/study_04/
• [Remarks] 東京大学大学院薬学系研究科 井上研究室ホームページ
  • URL: http://www.f.u-tokyo.ac.jp/~inoue/
• [Remarks] 東京大学 大学院農学生命科学研究科 獣医外科学研究室ホームページ
  • URL: http://www.vm.a.u-tokyo.ac.jp/geka/
• [Remarks] 東京工業大学生命理工学院 一瀬研究室ホームページ
  • URL: http://www.bh4.bio.titech.ac.jp/index.html
• [Remarks] 東京慈恵会医科大学 総合医科学研究センター渡部研究部ホームページ
  • URL: http://watabe-lab.jp/
• [Remarks] 東京農工大学大学院工学研究院応用化学分野 大栗研究室ホームページ
  • URL: http://web.tuat.ac.jp/~h_oguri/index.html
• [Remarks] 公益財団法人微生物化学研究所
  • URL: https://www.bikaken.or.jp
• [Remarks] 東京理科大学 生命医科学研究所 昆 俊亮 研究室 ホームページ
  • URL: https://konshunsukelab.wixsite.com/rs-tus
• [Remarks] 慶應義塾大学薬学部生化学講座ホームページ
  • URL: http://square.umin.ac.jp/keio-dbc/research.html
• [Remarks] 順天堂大学 医学部 小松雅明研究室ホームページ
  • URL: https://www.juntendo.ac.jp/graduate/laboratory/labo/kikan_saibou/
• [Remarks] 新学術領域研究マルチモードオートファジーホームページ
  • URL: http://proteolysis.jp/multimode_autophagy/
• [Remarks] 新潟大学脳研究所 動物資源開発研究分野 ホームページ
  • URL: http://www.bri.niigata-u.ac.jp/field/lab_animal/index.html
• [Remarks] 新潟大学脳研究所 脳研コラム ホームページ
  • URL: http://www.bri.niigata-u.ac.jp/result/lab_animal/000126.html
• [Remarks] 新潟大学脳研究所 研究成果・実績 ホームページ
  • URL: http://www.bri.niigata-u.ac.jp/result/lab_animal/000833.html
• [Remarks] 新潟大学大学院医歯学総合研究科機能制御学分野のホームページ
  • URL: https://www.med.niigata-u.ac.jp/mit/
• [Remarks] 新潟大学医歯学系神経生化学(生化学第二)ホームページ
  • URL: https://www.med.niigata-u.ac.jp/bc2/index.html
• [Remarks] 新潟大学脳研究所 研究業績ホームページ
  • URL: http://www.bri.niigata-u.ac.jp/result/surgery/001033.html
• [Remarks] 新潟大学脳研究所ホームページ
  • URL: https://www.bri.niigata-u.ac.jp/research/result/surgery/001521.html
• [Remarks] 新潟大学脳研究所 動物資源開発研究分野ホームページ
  • URL: https://www.bri.niigata-u.ac.jp/field/lab_animal/index.html
• [Remarks] 新潟大学脳研究所 研究成果ホームページ「D1ドーパミン受容体を介する神経情報伝達が文脈的恐怖条件付けの遠隔記憶の形成に重要な働きをすることを解明」
  • URL: https://www.bri.niigata-u.ac.jp/research/result/lab_animal/001664.html
• [Remarks] 富山大学薬学部分子神経生物学研究室ホームページ
  • URL: http://www.pha.u-toyama.ac.jp/biochel/index-j.html
• [Remarks] 金沢大学広報ホームページ
  • URL: https://www.kanazawa-u.ac.jp/latest-research/64909
• [Remarks] 金沢大学がん進展制御研究室腫瘍分子生物学研究分野ホームページ
  • URL: http://omb.w3.kanazawa-u.ac.jp/index.html
• [Remarks] 名古屋大学 環境医学研究所 神経系分野ホームページ
  • URL: http://www.riem.nagoya-u.ac.jp/4/neuroscience2/nr/
• [Remarks] 名古屋大学大学院医学系研究科統合生理学ホームページ
  • URL: https://www.med.nagoya-u.ac.jp/physio12/
• [Remarks] 基礎生物学研究所神経細胞生物学研究室ホームページ
  • URL: http://www.nibb.ac.jp/neurocel/index.html
• [Remarks] 自然科学研究機構 生理学研究所 細胞構造研究部門古瀬研究室ホームページ
  • URL: http://www.nips.ac.jp/dcs/
• [Remarks] 愛知県がんセンター研究所腫瘍制御学分野ホームページ
  • URL: http://www.pref.aichi.jp/cancer-center/ri/01bumon/06shuyo_uirusu/
• [Remarks] 名古屋市立大学分子毒性学分野ホームページ
  • URL: http://www.med.nagoya-cu.ac.jp/moltox.dir/
• [Remarks] 藤田医科大学医学部生化学講座ホームページ
  • URL: http://www.fujita-hu.ac.jp/~biocheml/index.html
• [Remarks] 滋賀医科大学分子病態生化学ホームページ
  • URL: http://www.shiga-med.ac.jp/~hqbioch2/
• [Remarks] 京都大学医学研究科 小川正晃研究室ホームページ
  • URL: https://sites.google.com/view/ogawagroup/
• [Remarks] 老化とアンチエイジング研究室ホームページ
  • URL: http://www.anti-aging.jpn.com/
• [Remarks] 生命有機化学研究室ホームページ
  • URL: http://www.orgchem.kais.kyoto-u.ac.jp/
• [Remarks] 京都産業大学 加藤啓子教授紹介ページ
  • URL: http://www.kyoto-su.ac.jp/faculty/professors/nls/kato-keiko.html
• [Remarks] 京都大学上杉志成研究室
  • URL: https://www.scl.kyoto-u.ac.jp/~uesugi/ja/index.php
• [Remarks] 新学術領域研究 温度生物学ハンドブック
  • URL: http://www.nips.ac.jp/thermalbio/handbook.html
• [Remarks] 大阪大学大学院医学系研究科疾患データサイエンス学共同研究講座ホームページ
  • URL: https://www2.med.osaka-u.ac.jp/mds/
• [Remarks] 大阪大学微生物病研究所分子免疫制御分野 山崎研究室ホームページ
  • URL: http://molimm.biken.osaka-u.ac.jp
• [Remarks] 大阪大学大学院医学系研究科 分子病態生化学ホームページ
  • URL: https://www.med.osaka-u.ac.jp/pub/molbiobc/
• [Remarks] 大阪市立大学大学院医学研究科分子病態学研究室ホームページ
  • URL: http://osaka-cu-lseika.umin.jp/
• [Remarks] 関西医科大学
  • URL: http://www.kmu.ac.jp/faculty/medical/category2/unit4.html
• [Remarks] 鳥取大学 細胞ゲノム機能学分野 研究室ホームページ
  • URL: https://www.google.co.jp/#spf=1601451705886
• [Remarks] 岡山大学大学院ヘルスシステム統合科学研究科ナノバイオシステム分子設計学ホームページ
  • URL: http://www.cyber.biotech.okayama-u.ac.jp/senolab/
• [Remarks] 広島大学 神経生理学ホームページ
  • URL: https://home.hiroshima-u.ac.jp/physio12/index.html
• [Remarks] 香川大学医学部薬理学研究室ホームページ
  • URL: http://www.kms.ac.jp/~yakuri/
• [Remarks] 九州大学生体防御医学研究所 分子医科学分野 ホームページ
  • URL: http://www.bioreg.kyushu-u.ac.jp/saibou/index.html
• [Remarks] 九州大学大学院薬学研究院 創薬腫瘍科学講座ホームページ
  • URL: http://shuyo.phar.kyushu-u.ac.jp/
• [Remarks] 福岡大学てんかん分子病態研究所ホームページ
  • URL: http://www.med.fukuoka-u.ac.jp/epilepsy/index.html
• [Remarks] 長崎国際大学薬学部 高井伸彦教授紹介ページ
  • URL: https://wwwl.niu.ac.jp/about/teacher/detail.html?tid=188
• [Remarks] 熊本大学発生医学研究所脳発生分野ホームページ
  • URL: http://www.imeg.kumamoto-u.ac.jp/bunya_top/brain_morphogenesis/
• [Remarks] 熊本大学国際先端医学研究所ホームページpublication欄
  • URL: http://ircms.kumamoto-u.ac.jp/publications/2017/01/identification-of-stem-cells-in-the-epithelium-of-the-stomach-corpus-and-antrum-of-mice.html
• [Remarks] 可変型遺伝子トラップクローンデータベース(EGTC)
  • URL: http://egtc.jp
• [Remarks] 熊本大学発生医学研究所ホームページ
  • URL: http://www.imeg.kumamoto-u.ac.jp/en/np91/
• [Remarks] 熊本大学発生医学研究所ホームページ
  • URL: http://www.imeg.kumamoto-u.ac.jp/np104/
• [Remarks] 熊本大学発生医学研究所 染色体制御分野ホームページ
  • URL: http://www.imeg.kumamoto-u.ac.jp/bunya_top/chromosome-biology/ronbun/
• [Remarks] 石黒啓一郎(熊本大学)研究紹介動画
  • URL: https://www.youtube.com/watch?v=47NhxgLdOmQ&t=5s
• [Remarks] 石黒啓一郎(熊本大学)研究紹介動画
  • URL: https://www.youtube.com/watch?v=1zAnyBYHLK0
• [Remarks] 鹿児島大学大学院医歯学総合研究科分子腫瘍学分野ホームページ
  • URL: http://www.kufm.kagoshima-u.ac.jp/~molonc12/
• [Patent(Industrial Property Rights)] 小児白血病に対する薬剤の有効性の判定を補助する方法、小児白血病に対する薬剤投与後の予後の判定を補助する方法及びキット (2021)
  • Inventor(s): 中川俊輔、河原康一、岡本康裕、古川龍彦
  • Industrial Property Rights Holder: 鹿児島大学
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 特願2021-070943
  • Overseas
• [Patent(Industrial Property Rights)] マクロ環含有新規テトラヒドロイソキノリンアルカロイド化合物 (2021)
  • Inventor(s): 大栗博毅, 谷藤 涼
  • Industrial Property Rights Holder: 大栗博毅, 谷藤 涼
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 特願2021-33773
  • Overseas
• [Patent(Industrial Property Rights)] 光学イメージング装置 (2021)
  • Inventor(s): 小山内 実, 虫明 元
  • Industrial Property Rights Holder: 東北大学
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: CN201780019699.8
  • Overseas
• [Patent(Industrial Property Rights)] 炎症レポーターシステム (2021)
  • Inventor(s): 山村研一、岩脇隆夫、及川大輔、石川智夫
  • Industrial Property Rights Holder: 株式会社トランスジェニック
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: ZL201480080906.7
  • Overseas