Research Project
①総括支援活動では、応募の機会増加の要望に応えるため今年度も年2回の公募とした。その結果、合計437の応募課題があり、213課題(49%)を採択した。コロナ禍の影響の中、昨年度より応募数は横ばいとなったが、支援内容の精査や支援経費の限度額設定等により、40%超の採択率を維持した。審査委員はすべてプラットフォーム外の専門家とし、評価が同程度の場合は若手、女性、少額科研費からの課題、初めての応募課題を優先した。支援課題は科研費生物系のほぼすべての分野に渡っており、支援の成果を含む論文として本年度に148報が発表された。この中には「大脳神経幹細胞の形成メカニズムの解明」(Nature Comm.)、「婦人科疾患の予防法開発につながる子宮内膜ゲノム異常の新知見」(Nature Comm.)、「ショウジョウバエを用いて性染色体進化の共通メカニズムを発見」(Genome Res.)、「葉緑体のゲノム編集に世界で初めて成功」(Plant Cell)など広い分野でのレベルの高い成果が含まれている。拡大班会議や情報解析講習会はオンサイト開催が必要なためにコロナ禍の中で見送ったが、WEB開催としたヒトゲノム研究倫理を考える会は4回開催し、各回約500名が参加した。②大規模配列解析拠点ネットワーク支援活動においては、最先端技術を支援に提供するとともに、染色体レベルの高精度ゲノム配列決定、シングルセル・空間遺伝子発現解析、全ゲノムメチル化解析手法の開発等の支援技術高度化を進めた。③高度情報解析支援ネットワーク活動では、支援から浮かび上がった課題を解決するソフトウェアの開発を進め、実際の課題への適用を進めた。本年度には、長鎖データを活用したメタゲノム決定アルゴリズムを開発、論文発表した。Hi-C法を使った染色体地図と転写活性解析やセントロメア多様性解析を進め、②と合わせて29報の論文を発表した。
令和3年度が最終年度であるため、記入しない。
令和3年度が最終年度であるため記入しない。
All 2022 2021 Other
All Int'l Joint Research (6 results) Journal Article (177 results) (of which Int'l Joint Research: 49 results, Peer Reviewed: 177 results, Open Access: 142 results) Presentation (398 results) (of which Int'l Joint Research: 75 results, Invited: 121 results) Book (13 results) Remarks (13 results)
ACR Open Rheumatology
10.1002/acr2.11425
Annals of Neurology
Volume: 91 Pages: 317-328
10.1002/ana.26304
BIO-PROTOCOL
Volume: 12 Pages: e4345
10.21769/bioprotoc.4345
BMC Bioinformatics
Volume: 23 Pages: 112
10.1186/s12859-022-04649-3
BMC Genomics
Volume: 23 Pages: 249
10.1186/s12864-022-08471-2
Cancer Cell
Volume: 40 Pages: 201-218. e9
10.1016/j.ccell.2022.01.001
Cancer Medicine
10.1002/cam4.4726
Cancer Science
Volume: 113 Pages: 1097-1104
10.1111/cas.15279
Cell Genomics
Volume: 2 Pages: 100101
10.1016/j.xgen.2022.100101
Clinical Genetics
Volume: 101 Pages: 335-345
10.1111/cge.14103
Communications Biology
Volume: 5 Pages: 287
10.1038/s42003-022-03241-y
Endocrinology
Volume: 163 Pages: bqac044
10.1210/endocr/bqac044
Environmental and Experimental Botany
Volume: 196 Pages: 104724
10.1016/j.envexpbot.2021.104724
Frontiers in Microbiology
Volume: 13 Pages: 849667
10.3389/fmicb.2022.849667
Frontiers in Pharmacology
Volume: 13 Pages: 842717
10.3389/fphar.2022.842717
Gastroenterology
Volume: 162 Pages: 1272-1287. e16
10.1053/j.gastro.2021.12.254
Genes to Cells
10.1111/gtc.12929
Genome Research
Volume: 32 Pages: 945-955
10.1101/gr.276363.121
Human Cell
Volume: 35 Pages: 767-770
10.1007/s13577-021-00665-2
Journal of Antimicrobial Chemotherapy
Volume: 77 Pages: 1202-1204
10.1093/jac/dkac006
Journal of Comparative Neurology
10.1002/cne.25314
Microbial genomics
Volume: 8 Pages: 000676
10.1099/mgen.0.000676
Microbiology Resource Announcements
Volume: 11 Pages: e0110621
10.1128/mra.01106-21
Microorganisms
Volume: 10 Pages: 196
10.3390/microorganisms10010196
microPublication Biology.
10.17912/micropub.biology.000526
Molecular Genetics and Metabolism
Volume: S1096-7192 Pages: 00126-3
10.1016/j.ymgme.2022.01.100
mSystems
Volume: 7 Pages: e0001822
10.1128/msystems.00018-22
NAR Genomics and Bioinformatics
Volume: 4 Pages: lqac012
10.1093/nargab/lqac012
Nature Communications
Volume: 13 Pages: 470
10.1038/s41467-022-28097-y
Volume: 13 Pages: 943
10.1038/s41467-022-28568-2
npj Biofilms and Microbiomes
Volume: 8 Pages: 17
10.1038/s41522-022-00278-z
Nucleic Acids Research
10.1093/nar/gkac220
Plant Signaling & Behavior
Volume: 17 Pages: 2046412
10.1080/15592324.2022.2046412
PLOS Genetics
Volume: 18 Pages: e1009979
10.1371/journal.pgen.1009979
Proceedings of the Japan Academy, Series B
Volume: 98 Pages: 126-139
10.2183/pjab.98.009
Proceedings of the National Academy of Sciences
Volume: 119 Pages: e2121177119
10.1073/pnas.2121177119
Volume: 119 Pages: e2110361119
10.1073/pnas.2110361119
Science Advances
Volume: 8 Pages: eabi5075
10.1126/sciadv.abi5075
Volume: 8 Issue: 11 Pages: eabi6375
10.1126/sciadv.abi6375
Science Signaling
Volume: 15 Pages: eabm5011
10.1126/scisignal.abm5011
Scientific Reports
Volume: 12 Pages: 1318
10.1038/s41598-022-05248-1
Sustainability
Volume: 14 Pages: 1617
10.3390/sul4031617
Frontiers in Marine Science
Volume: 8 Pages: 688139
10.3389/fmars.2021.688139
Journal of Plant Research
Volume: 135 Pages: 3-14
10.1007/s10265-021-01349-6
Mammalian Genome
Volume: 33 Pages: 382-401
10.1007/s00335-021-09881-5
Molecular Microbiology
Volume: 117 Pages: 160-178
10.1111/mmi.14814
2021 Ninth International Symposium on Computing and Networking (CANDAR)
Pages: 102-107
10.1109/candar53791.2021.00021
Algal Resources
Volume: 13 Pages: 33-39
10.20804/jsap.13.2_33
Biochemistry and Biophysics Reports
Volume: 27 Pages: 101072
10.1016/j.bbrep.2021.101072
BioEssays
Volume: 43 Pages: 2100155
10.1002/bies.202100155
Bioinformatics
Volume: 38 Pages: 710-719
10.1093/bioinformatics/btab738
Volume: 37 Pages: 3944-3946
10.1093/bioinformatics/btab492
Volume: 37 Pages: i16-i24
10.1093/bioinformatics/btab287
Bioinformatics Advances
Volume: 1 Pages: vbab014
10.1093/bioadv/vbab014
Biological Reviews
Volume: 97 Pages: 115-140
10.1111/brv.12791
Biology
Volume: 10 Pages: 300
10.3390/biology10040300
Biomedicines
Volume: 9 Pages: 1892
10.3390/biomedicines9121892
Volume: 9 Pages: 1012
10.3390/biomedicines9081012
Bioscience, Biotechnology, and Biochemistry
Volume: 85 Pages: 851-859
10.1093/bbb/zbaa091
Volume: 22 Pages: 554
10.1186/s12859-021-04430-y
Volume: 22 Pages: 427
10.1186/s12859-020-03737-6
Volume: 22 Pages: 481
10.1186/s12864-021-07803-y
Volume: 22 Pages: 730
10.1186/s12864-021-08038-7
Boundary-Layer Meteorology
Volume: 179 Pages: 447-476
10.1007/s10546-021-00604-6
British Journal of Cancer
Volume: 126 Pages: 109-119
10.1038/s41416-021-01579-4
Cancer Res
Volume: 81 Pages: 5413-5424
10.1158/0008-5472.can-21-0356
Carcinogenesis
Volume: 42 Pages: 1239-1249
10.1093/carcin/bgab088
Cell Reports
Volume: 36 Pages: 109383
10.1016/j.celrep.2021.109383
Volume: 35 Pages: 109124
10.1016/j.celrep.2021.109124
Volume: 4 Pages: 796
10.1038/s42003-021-02297-6
Volume: 4 Pages: 733
10.1038/s42003-021-02197-9
Volume: 4 Pages: 463
10.1038/s42003-021-01984-8
Computational and Structural Biotechnology Journal
Volume: 19 Pages: 4207-4216
10.1016/j.csbj.2021.07.030
Volume: 19 Pages: 3198-3208
10.1016/j.csbj.2021.05.039
Current Biology
Volume: 31 Pages: 5522-5532. e7
10.1016/j.cub.2021.10.023
Current Opinion in Biotechnology
Volume: 70 Pages: 248-254
10.1016/j.copbio.2021.06.011
Development
Volume: 148 Pages: dev198507.
10.1242/dev.198507
Volume: 148 Pages: dev196212.
10.1242/dev.196212
Diagnostics
Volume: 11 Pages: 1364
10.3390/diagnostics11081364
Digestive Diseases
10.1159/000518538
DNA Research
Volume: 28 Pages: dsab012.
10.1093/dnares/dsab012
Volume: 28 Pages: dsab004.
10.1093/dnares/dsab004
Volume: 28 Pages: dsab021
10.1093/dnares/dsab021
eLife
Volume: 10 Pages: e71966.
10.7554/elife.71966
Volume: 10 Pages: e66954.
10.7554/elife.66954
Volume: 10 Pages: e66290.
10.7554/elife.66290
EMBO Journal
Volume: 40 Pages: e107976.
10.15252/embj.2021107976
Volume: 40 Pages: e106434.
10.15252/embj.2020106434
Environmental Microbiology
Volume: 23 Pages: 5621-5638
10.1111/1462-2920.15724
FEMS Microbiology Ecology
Volume: 97 Pages: fiab167
10.1093/femsec/fiab167
Fisheries Science
Volume: 87 Pages: vbab014
10.1007/s12562-021-01550-5
Frontiers in Cardiovascular Medicine
Volume: 8 Pages: 789325
10.3389/fcvm.2021.789325
Frontiers in Fungal Biology
Volume: 2 Pages: 656751
10.3389/ffunb.2021.656751
Frontiers in Genetics
Volume: 12 Pages: 625797
10.3389/fgene.2021.625797
Volume: 12 Pages: 740610
10.3389/fmicb.2021.740610
G3 : GENES, GENOMES, GENETICS
Volume: 11 Pages: jkab243.
10.1093/g3journal/jkab243
Genes
Volume: 12 Pages: 1110
10.3390/genes12081110
Volume: 12 Pages: 758
10.3390/genes12050758
Genes & Development
Volume: 35 Pages: 1431-1444
10.1101/gad.348797.121
Genes and Environment
Volume: 43 Pages: 35
10.1186/s41021-021-00211-4
Genome Biology and Evolution
Volume: 13 Pages: evab242
10.1093/gbe/evab242
Volume: 13 Pages: evab192
10.1093/gbe/evab192
Volume: 31 Pages: 2069-79
10.1101/gr.275503.121
Volume: 31 Pages: 968-980
10.1101/gr.269951.120
Gut Pathogens
Volume: 13 Pages: 36
10.1186/s13099-021-00432-6
Gynecologic Oncology
Volume: 163 Pages: 327-333
10.1016/j.ygyno.2021.08.009
Helicobacter
Volume: 26 Pages: e12790
10.1111/hel.12790
Volume: 34 Pages: 1727-1733
10.1007/s13577-021-00609-w
Immunological Reviews
Volume: 304 Pages: 97-110
10.1111/imr.13023
Inflammation and Regeneration
Volume: 41 Pages: 31
10.1186/s41232-021-00182-7
International Journal of Cardiology
Volume: 338 Pages: 138-142
10.1016/j.ijcard.2021.06.003
International Journal of Molecular Sciences
Volume: 23 Pages: 51
10.3390/ijms23010051
Volume: 22 Pages: 7544
10.3390/ijms22147544
Volume: 22 Pages: 7278
10.3390/ijms22147278
Volume: 22 Pages: 5421
10.3390/ijms22115421
Volume: 22 Pages: 4795
10.3390/ijms22094795
Volume: 22 Pages: 2238
10.3390/ijms22052238
Volume: 22 Pages: 632
10.3390/ijms22020632
IOVS
Volume: 62 Pages: 1
10.1167/iovs.62.6.1
iScience
Volume: 24 Pages: 102890
10.1016/j.isci.2021.102890
Journal of Biological Chemistry
Volume: 297 Pages: 101367
10.1016/j.jbc.2021.101367
Journal of Evolutionary Biology
Volume: 34 Pages: 1767-1780
10.1111/jeb.13932
Journal of Medicinal Chemistry
Volume: 64 Pages: 14153-14164
10.1021/acs.jmedchem.1c01319
Journal of Molecular Endocrinology
Volume: 66 Pages: 299-311
10.1530/jme-20-0325
Journal of Reproduction and Development
Volume: 67 Pages: 369-379
10.1262/jrd.2021-106
Journal of the Japan Veterinary Medical Association
Volume: 74 Pages: 389-395
10.12935/jvma.74.389
Microbes and Environments
Volume: 36 Pages: ME21035
10.1264/jsme2.me21035
Microbial Ecology
Volume: 82 Issue: 2 Pages: 512-522
10.1007/s00248-021-01686-y
Microbial Genomics
Volume: 7 Pages: 000680
10.1099/mgen.0.000680
Volume: 7 Pages: 523
10.1099/mgen.0.000523
Volume: 9 Pages: 1953
10.3390/microorganisms9091953
microPub Biology
Pages: 446
10.17912/micropub.biology.000446
Mitochondrial DNA Part B : Resources
Volume: 6 Pages: 1451-1453
10.1080/23802359.2021.1911710
Molecular and Cellular Biology
Volume: 41
10.1128/mcb.00303-21
Molecular Biology and Evolution
Volume: 38 Pages: 3033-3045
10.1093/molbev/msab098
Molecular Brain
Volume: 14 Pages: 160
10.1186/s13041-021-00869-5
Molecular Cell
Volume: 81 Pages: 3018-3030. e5
10.1016/j.molcel.2021.05.009
Volume: 3 Pages: lqab093
10.1093/nargab/lqab093
Volume: 3 Pages: lqab055
10.1093/nargab/lqab055
Volume: 3 Issue: 1 Pages: lqab021
10.1093/nargab/lqab021
Nature
Volume: 592 Pages: 756-762
10.1038/s41586-020-03039-0
Nature Cell Biology
Volume: 23 Pages: 1002-1012
10.1038/s41556-021-00745-3
Volume: 12 Pages: 6562
10.1038/s41467-021-26605-0
Volume: 12 Pages: 3773
10.1038/s41467-021-23987-z
Volume: 12 Pages: 3244
10.1038/s41467-021-23457-6
Nature Plants
Volume: 7 Pages: 906-913
10.1038/s41477-021-00954-6
Nature Structural & Molecular Biology
Volume: 28 Pages: 487-500
10.1038/s41594-021-00602-9
New Phytologist
Volume: 233 Pages: 569-578
10.1111/nph.17763
Volume: 232 Pages: 1582-1590
10.1111/nph.17615
Nucleic acids research
Volume: 49 Pages: e130
10.1093/nar/gkab831
Volume: 49 Pages: e81-e81
10.1093/nar/gkab397
Oncotarget
Volume: 12 Pages: 1687-1696
10.18632/oncotarget.28035
Plant Cell Reports
Volume: 41 Pages: 263-275
10.1007/s00299-021-02806-1
Plant Direct
Volume: 5 Pages: e352
10.1002/pld3.352
Plant Molecular Biology
Volume: 107 Pages: 431-449
10.1007/s11103-021-01214-z
Plant Physiology
Volume: 185 Pages: 1429-1442
10.1093/plphys/kiab005
PLOS ONE
Volume: 16 Pages: e0237554
10.1371/journal.pone.0237554
PLoS One
Volume: 16 Pages: e0259846
10.1371/journal.pone.0259846
Volume: 118 Pages: e2103658118
10.1073/pnas.2103658118
Volume: 118 Pages: e2108281118
10.1073/pnas.2108281118
Volume: 118 Pages: e2100712118
10.1073/pnas.2100712118
Rheumatology
Volume: 61 Pages: 1276-1281
10.1093/rheumatology/keab545
Volume: 11 Pages: 22231
10.1038/s41598-021-01521-x
Volume: 11 Pages: 20472
10.1038/s41598-021-98940-7
Volume: 11 Pages: 19304
10.1038/s41598-021-98805-z
STAR Protocols
Volume: 2 Pages: 100780
10.1016/j.xpro.2021.100780
Volume: 2 Pages: 100540
10.1016/j.xpro.2021.100540
STEM CELLS
Volume: 39 Pages: 929-944
10.1002/stem.3359
Volume: 13 Pages: 4590
10.3390/sul3084590
The EMBO Journal
Volume: 40 Pages: e107485
10.15252/embj.2020107485
Volume: 40 Issue: 18 Pages: e108345
10.15252/embj.2021108345
The International Journal of Biochemistry & Cell Biology
Volume: 136 Pages: 106001
10.1016/j.biocel.2021.106001
The Journal of Biochemistry
Volume: 169 Pages: 629-632
10.1093/jb/mvab040
Volume: 169 Pages: 421-434
10.1093/jb/mvaa143
The Plant Genome
Volume: 14 Issue: 3 Pages: e20157
10.1002/tpg2.20157
Virus Genes
Volume: 57 Pages: 459-463
10.1007/s11262-021-01858-5
https://www.genome-sci.jp/
https://github.com/JasonYangShadow/lpmx
http://iwasakilab.k.u-tokyo.ac.jp/sonicparanoid/
https://msk33.github.io/prokatlas.html
http://spinach.kazusa.or.jp/
https://marchantia.info
https://dfast.nig.ac.jp/