2017 Fiscal Year Final Research Report
Effects of stress on rhythmical masticatory muscle activity duirng sleep
| Project/Area Number |
16H06961
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Prosthodontics/ Dental materials science and
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| Research Institution | Osaka University |
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Principal Investigator |
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| Project Period (FY) |
2016-08-26 – 2018-03-31
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| Keywords | ブラキシズム / ストレス / 睡眠 |
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| Outline of Final Research Achievements |
Rhythmic masticatory muscle activity (RMMA) was found to occur during NREM sleep in guinea pigs.Physiological characteristics were similar to RMMA in humans, as the occurrence of RMMA was associated with arousal processes. Electromyographic characteristics of RMMA in guinea pigs were also similar to those in humans. Using this animal model, experimental stress was given to the freely moving guinea pigs. During two hours after experimental stress, animals had less sleep but more RMMA. After then, these variables returned to the baseline level (i.e., without stress). Rhythmic masseter activity was found to be triggered when micro-electrical stimulations were given to the ventral areas of amygdala in anesthetized guinea pigs. These suggest that experimental stress can increase the generation of RMMA and the roles of amygdala need to be investigated in the future study.
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| Free Research Field |
歯科補綴学
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