Development of novel antimicrobial hybrid biomaterial aiming at application to osteomyelitis of jaw

2017 Fiscal Year Final Research Report

• Project/Area Number: 16H07458
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Surgical dentistry
• Research Institution: National Defense Medical College
• Principal Investigator: MURAKAMI Kaoru 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 病院 歯科口くう外科, 講師 (50778462)
• Project Period (FY): 2016-08-26 – 2018-03-31
• Keywords: 抗菌性 / 銀ナノ粒子 / 生体材料 / 骨補填材

Outline of Final Research Achievements

Jaw osteomyelitis is a typical odontogenic infection, and it is often difficult to treat. We focused on silver nanoparticles with high antibacterial activity to control jaw osteomyelitis and developed the method to synthesize silver nanoparticles conveniently and efficiently. It was confirmed that biocompatible chitosan with nanoporous surface structure , β-TCP, atelocollagen sponge have strong antibacterial activity

Free Research Field

口腔外科学