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2018 Fiscal Year Final Research Report

Evaluation of nutritional status by analysis of stable isotope ratio and trance elements in scalp hair and application to medical cares

Research Project

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Project/Area Number 16K00863
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Eating habits
Research InstitutionHealth Sciences University of Hokkaido

Principal Investigator

ENDO Tetsuya  北海道医療大学, 薬学部, 准教授 (10133216)

Co-Investigator(Kenkyū-buntansha) 木村 治  北海道医療大学, 薬学部, 講師 (10418882)
Research Collaborator KIMURA Osamu  
Project Period (FY) 2016-04-01 – 2019-03-31
Keywords頭髪 / 炭素安定同位体 / 窒素安定同位体 / 微量元素 / 経腸栄養 / 中心静脈栄養 / 糖尿病 / クローン病
Outline of Final Research Achievements

The aim of the study by measuring carbon and nitrogen stable isotopes and trace elements in the scalp hair is the evaluation of patient's nutritional status and application to diagnosis and treatment of diseases related to food. The main targets are patients who have been under nutritional management for a long time with enteral nutrition or total parenteral nutrition, diabetes patients, and Crohn's disease patients.

Free Research Field

栄養学 衛生学 環境衛生学

Academic Significance and Societal Importance of the Research Achievements

頭髪は血液と比べて採取が容易で、感染の心配もない。また保存や運搬も容易である。頭髪は1月に約1cm伸長することから、長期間の情報を得ることが可能である。慢性的な疾病の診断や栄養状態の推定に適した生体試料である。本研究では、頭髪中の炭素および窒素安定同位体と各種微量元素を測定することで、食に関する疾病を診断を試みた。

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Published: 2020-03-30  

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