Five-year follow-up of the large-scale cohort study on vitamin D for the prevention of age- and lifestyle-related diseases

2019 Fiscal Year Final Research Report

• Project/Area Number: 16K09078
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Epidemiology and preventive medicine
• Research Institution: Niigata University of Health and Welfare
• Principal Investigator: saito toshiko 新潟医療福祉大学, 健康科学部, 教授 (40339958)
• Co-Investigator(Kenkyū-buntansha): 中村 和利 新潟大学, 医歯学系, 教授 (70207869)
• Project Period (FY): 2016-04-01 – 2020-03-31
• Keywords: ビタミンD / コホート研究 / 加齢性疾患 / 生活習慣病 / 予防医学

Outline of Final Research Achievements

This study was conducted to determine blood 25-hydroxyvitamin D concentrations of 1044 subjects among participants of the 5-year follow-up investigation of the large-scale vitamin D cohort study. We identified predictors of vitamin D decline, including education, outdoor occupation, physical activity, and green tea consumption. We also found sex-difference in such association. In addition, information on new cases of age- and lifestyle-related diseases has been obtained.

Free Research Field

疫学・予防医学

Academic Significance and Societal Importance of the Research Achievements

加齢性疾患・生活習慣病予防の観点からビタミンDの重要性が世界的に注目されている。このような状況の下、私たちはビタミンD低下に関わる要因を縦断的に調査し特定した。本研究は大規模かつ縦断研究である点が評価され、British Journal of Nutrition誌に掲載が決定した。また本研究は地域住民の生活習慣に関連した要因を直接特定でき、一般住民の健康増進に有用な情報を提供できたことは社会的に意義深い。