The gut-brain axis examined by wireless optogenetics

2017 Fiscal Year Final Research Report

• Project/Area Number: 16K13110
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Basic / Social brain science
• Research Institution: Institute of Physical and Chemical Research
• Principal Investigator: Takumi Toru 国立研究開発法人理化学研究所, 脳科学総合研究センター, チームリーダー (00222092)
• Co-Investigator(Renkei-kenkyūsha): YAMANAKA Akihiro 名古屋大学, 環境医学研究所, 教授 (60323292)
• Project Period (FY): 2016-04-01 – 2018-03-31
• Keywords: 脳腸連関 / 腸内フローラ / 自閉症

Outline of Final Research Achievements

The gut is called as the second brain and the gut-brain axis is an interesting network between organs for higher brain functions including cognitive function. To understand the higher brain function regulated by the autonomic nervous system, we develop the wire-less optogenetics to physiologically see the activity of the autonomic nervous system and the enteric nerves with relatively lower invasiveness. The results of this study will be a tool to examine the regulatory network between different organs.

Free Research Field

基盤脳科学