2017 Fiscal Year Final Research Report
Design of peptide probes capable of recognizing highly-curved membranes for exosome analysis
Project/Area Number |
16K14013
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Analytical chemistry
|
Research Institution | Tohoku University |
Principal Investigator |
Sato yusuke 東北大学, 理学研究科, 助教 (90583039)
|
Project Period (FY) |
2016-04-01 – 2018-03-31
|
Keywords | 蛍光プローブ / 両親媒性αヘリックス / エクソソーム |
Outline of Final Research Achievements |
We developed fluorescent probes based on amphipathic αhelix peptide (22 residues from C-terminal of ApoA-I) that can selectively recognize highly-curved membranes found in exosomes. Our method allows easier, simpler and more rapid detection of exosomes.
|
Free Research Field |
生命分析科学
|