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2017 Fiscal Year Final Research Report

Development of a novel construction method of polyploid in yeast

Research Project

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Project/Area Number 16K14894
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Applied microbiology
Research InstitutionSojo University

Principal Investigator

HARASHIMA Satoshi  崇城大学, 生物生命学部, 教授 (70116086)

Co-Investigator(Kenkyū-buntansha) 浴野 圭輔  崇城大学, 生物生命学部, 准教授 (30310030)
Project Period (FY) 2016-04-01 – 2018-03-31
Keywords酵母 / "超"高次倍数体
Outline of Final Research Achievements

How ploidy in organisms is controlled is one of the important issues in modern biology. Industrial strains of budding yeast is well known to be polyploid is also interesting fact in biotechnology in connection with useful characteristics. However, research regarding physiological significance of ploidy is not advanced due to unavailable technology to construct polyploid at will. In this study, we have developed a novel breeding technology to construct a series of polyploid strain by using a specific mutation of mating type αin budding yeast. We have created hexaploid, octoploid and decaploid using this technique. We are now challenging whether more higher polyploid strain could be created.

Free Research Field

応用微生物学

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Published: 2019-03-29  

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