2017 Fiscal Year Final Research Report
Selective Synthetic Methodology Through the Control of Intramolecular Rearragements
| Project/Area Number |
16K17898
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Synthetic chemistry
|
|---|
| Research Institution | Kyoto University |
|---|
Principal Investigator |
Kim Heejin 京都大学, 工学研究科, 特定助教 (80754514)
|
|---|
| Project Period (FY) |
2016-04-01 – 2018-03-31
|
| Keywords | selective synthesis / intramolecular reaction / flow chemistry / microreactor / Fries rearrangement / Wittig rearrangement |
|---|
| Outline of Final Research Achievements |
In this research, we developed the selective synthetic methods for controlling extremely fast intramolecular rearrangements using micro flow system. In detail, we used micro flow system for precise control of extremely short reaction time which is important for the chemical reaction involving the rapid intramolecular rearrangement. For example, Fries rearrangement and Wittig rearrangement were studied as the research target, and the selective synthesis of valuable compounds such as the biologically active molecules was achieved.
|
| Free Research Field |
Organic synthesis
|
