2017 Fiscal Year Final Research Report
The effect of erythrocyte-derived microvesicles on the malignant potential of gastric cancer
| Project/Area Number |
16K19948
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Digestive surgery
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| Research Institution | Kyoto Prefectural University of Medicine |
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Principal Investigator |
Arita Tomohiro 京都府立医科大学, 医学(系)研究科(研究院), 助教 (00756794)
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| Research Collaborator |
KONISHI Hirotaka 京都府立医科大学, 消化器外科, 助教
KOMATSU Shuhei 京都府立医科大学, 消化器外科, 特任講師
SHIOZAKI Atsushi 京都府立医科大学, 消化器外科, 講師
ICHIKAWA Daisuke 山梨大学, 総合研究部, 教授
OTSUJI Eigo 京都府立医科大学, 消化器外科, 教授
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Keywords | extracellular vesicle / erythrocyte / exosome / gastric cancer |
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| Outline of Final Research Achievements |
Erythrocyte-derived microvesicles (EDM) were ingested into the cellular cytoplasm using fluorescence microscopy. EDMs from patients with gastric cancer enhanced the adhesive, wound healing and migratory ability of gastric cancer cell. Several oncogenes were up-regulated in EDM-ingested gastric cancer cell.
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| Free Research Field |
消化器外科学
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