2017 Fiscal Year Final Research Report
Elucidation of recurrence mechanism of IgA nephropathy after kidney transplantation from structural analysis of IgA1 O-glycans
Project/Area Number |
16K20132
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Urology
|
Research Institution | Osaka University |
Principal Investigator |
|
Research Collaborator |
IMAMURA ryoichi 大阪大学, 医学系研究科, 准教授
Wada yoshinao 大阪府立母子保健総合医療センター, 研究所, 前所長
Iwatani hirotsugu 国立大阪医療センター, 腎臓内科, 部長
|
Project Period (FY) |
2016-04-01 – 2018-03-31
|
Keywords | IgA腎症 / 腎移植 |
Outline of Final Research Achievements |
In O-glycans analysis using MALDI-TOF-MS, GalNAc and Gal content in HR of IgAN recipients were significantly decreased than IgAD donors and healthy donors. However, in all patterns of O-glycans, there was no significant difference between IgAD donors and healthy donors.
|
Free Research Field |
腎移植
|