Influence of insufficient sleep in children on erectile function; a study in the rat.

2017 Fiscal Year Final Research Report

• Project/Area Number: 16K20155
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Urology
• Research Institution: Nagoya City University
• Principal Investigator: KATAOKA TOMOYA 名古屋市立大学, 大学院医学研究科, 助教 (20737928)
• Research Collaborator: FUKAMOTO Ayako 名古屋市立大学, 薬学部, 学部生 ; ASANO Gakuto 名古屋市立大学, 薬学部, 学部生 ; HIDAKA Junya 名古屋市立大学, 薬学部, 学部生 ; SUZUKI Jun 名古屋市立大学, 薬学部, 学部生 ; HOTTA Yuji 名古屋市立大学, 大学院薬学研究科, 講師 (90637563) ; MAEDA Yasuhiro 名古屋市立大学, 大学院薬学研究科, 講師 (60275146) ; KIMURA Kazunori 名古屋市立大学, 大学院医学研究科, 教授 (00423848)
• Project Period (FY): 2016-04-01 – 2018-03-31
• Keywords: 睡眠障害 / 勃起障害 / テストステロン

Outline of Final Research Achievements

We made sleep disorder model rats and investigated the effect on the sexual function. Normally, rats were raised under a light / dark cycle every 12 hours, but a chronic jet lag (CJL) treatment was performed which performed a process of advancing the light / dark cycle by 8 hours every 2 days. The ICP/MAP ratio was 0.81 ± 0.12 at 1 week after CJL treatment, and no change was observed. In addition, after 2 weeks it was 0.73 ± 0.12, which did not change, but after 4 weeks a significant decrease of 0.35 ± 0.05 was observed. When the expression of eNOS and phosphorylated eNOS was examined by western blotting method using the corpus cavernosum of rats 4 weeks after CJL treatment, significant decreases were observed in the CJL treatment group.

Free Research Field

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