2009 Fiscal Year Final Research Report
Analysis of developmental mechanisms based on functional genomic information of the nematode C. elegans
| Project/Area Number |
17017038
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| Research Category |
Grant-in-Aid for Scientific Research on Priority Areas
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| Allocation Type | Single-year Grants |
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| Review Section |
Biological Sciences
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| Research Institution | The Institute of Physical and Chemical Research |
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Principal Investigator |
SUGIMOTO Asako The Institute of Physical and Chemical Research, 発生ゲノミクス研究チーム, チームリーダー (80281715)
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| Co-Investigator(Kenkyū-buntansha) |
ONAMI Shuichi 独立行政法人理化学研究所, 発生システムモデル化研究チーム, チームリーダー (50348843)
KIMURA Akatsuki 慶應義塾大学, 大学院・理工学研究科, 助手 (10365447)
KYODA Koji 独立行政法人理化学研究所, 合成ゲノミクス研究チーム, 研究員 (30415145)
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| Project Period (FY) |
2005 – 2009
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| Keywords | ゲノム / 遺伝子 / 発生・分化 / モデル化 / ライブイメージング / 画像処理 / バイオイメージインフォマティクス |
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| Research Abstract |
To understand the genetic networks that control animal development, the following were performed using the early embryogenesis of the nematode C.elegans
as a model system. 1) Development of tools (such as GFP/RFP-tagged protein markers and monoclonal antibodies) and imaging techniques, and imaging data collection, 2) Computational analysis of the phenotype image data, and 3) Development of research strategy that integrate quantitative phenotype analysis and simulation.
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[Presentation] Computational analysis of quantitative information of cell division dynamics of early embryos.2009
Author(s)
Kyoda, K., Adachi, E., Shimada, K., Kuramochi, J., Onami, S.
Organizer
17th International C. elegans Meeting.
Place of Presentation
LA, USA
Year and Date
20090624-20090628
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