2009 Fiscal Year Final Research Report
Analysis for genes specifically expressed in primate neocotical areas
| Project/Area Number |
17024055
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| Research Category |
Grant-in-Aid for Scientific Research on Priority Areas
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| Allocation Type | Single-year Grants |
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| Review Section |
Biological Sciences
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| Research Institution | National Institute for Basic Biology |
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Principal Investigator |
YAMAMORI Tetsuo National Institute for Basic Biology, 脳生物学研究部門, 教授 (80260206)
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| Co-Investigator(Kenkyū-buntansha) |
WATAKABE Akiya 基礎生物学研究所, 脳生物学研究部門, 助教 (40290910)
KOMINE Yuriko 基礎生物学研究所, 脳生物学研究部門, 助教 (90280586)
SADAKANE Osamu 基礎生物学研究所, 脳生物学研究部門, 助教 (90446261)
ONOE Hirotaka 独立行政法人理化学研究所, 分子イメージング科学研究センター 分子プローブ機能評価研究チーム, チームリーダー (80214196)
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| Project Period (FY) |
2005 – 2009
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| Keywords | 大脳皮質 / 領野 / 遺伝子発現 / 連合野 / 視覚野 |
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| Research Abstract |
We have identified the genes that are markedly expressed in primate neocortical areas by a large scale analysis and found that these genes can be classified into two groups: The primary visual area specific and association area specific genes. The two areas are highly developed in the primate neocortex and thus these genes may play certain important roles in the specification of the primate areas. We have also identified roles of 5HT1B and 5HT2A serotonin receptors.
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[Journal Article] Enriched expression of serotonin 1B and 2A receptor genes in macaque visual cortex and their bidirectional modulatory effects on neuronal responses.2009
Author(s)
Watakabe A, Komatsu Y, Sadakane O, Shimegi S, Takahata T, Higo N, Tochitani S, Hashikawa T, Naito T, Osaki H, Sakamoto H, Okamoto M, Ishikawa A, Hara S, Akasaki T, Sato H, Yamamori T.
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Journal Title
Cereb Cortex. 19(8)
Pages: 1915-1928
Peer Reviewed
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