Fabrication of 3D Artificial Fine Blood Vessel Model Based on Personal Data

2009 Fiscal Year Final Research Report

• Project/Area Number: 17076015
• Research Category: Grant-in-Aid for Scientific Research on Priority Areas
• Allocation Type: Single-year Grants
• Review Section: Science and Engineering
• Research Institution: Fujita Health University
• Principal Investigator: NEGORO Makoto Fujita Health University, 医学部, 客員教授 (90115618)
• Co-Investigator(Kenkyū-buntansha): ARAI Fumihito 東北大学, 大学院・工学研究科, 教授 (90221051)
• Project Period (FY): 2005 – 2009
• Keywords: 微細加工 / 人工血管 / 3次元造形 / 生分解性材料 / 再生医学 / 脳神経外科 / ソルトリーチング / 個人情報

Research Abstract

Based on the personal data obtained by the medical tomography, such as CT (Computed Tomography) and MRI (Magnetic Resonance Imaging) etc., basis of the innovative medical technologies are researched as follows. (1) Design and fabrication of 3 dimensional blood vessel scaffold based on the personal data of patient. (2) Formation of vascular endothelial cells on the scaffold. (3) Minimally invasive surgical procedure to deriver artificial vessel.

Research Products

• [Journal Article] (2009)
  • Author(s): 中野琢磨, 吉田圭佑, 池田誠一, 大浦裕就, 福田敏男, 松田武久, 根来真, 新井史人
  • Journal Title: 日本ロボット学会誌 Vol.27,No.7 Pages: 725-731
  • Peer Reviewed
• [Journal Article] Development of biodegradable scaffolds based on patient-specific arterial configuration (2008)
  • Author(s): T. Uchida, S. Ikeda, H. Oura, M. Tada, T. Nakano, T. Fukuda, T. Matsuda, M. Negoro, F. Arai
  • Journal Title: Journal of Biotechnology 133 Pages: 213-218
  • Peer Reviewed
• [Journal Article] Fabrication of Transparent Arteriole Membrane Models (2008)
  • Author(s): T. Nakano, K. Yoshida, S. Ikeda, H. Oura, T. Fukuda, T. Matsuda, M. Negoro, F. Arai
  • Journal Title: Proc. 2008 Int. Symp. Micro-NanoMechatronics and Human Science Pages: 457-462
  • Peer Reviewed
• [Journal Article] Construction of Biodegradable Polymer Scaffold by Photolithography (2008)
  • Author(s): T. Itoyama, T. Nakano, H. Maruyama, S. Ikeda, H. Oura, T. Fukuda, T. Matsuda, M. Negoro, F. Arai
  • Journal Title: Proc. 2008 Int. Symp. Micro-NanoMechatronics and Human Science Pages: 361-366
  • Peer Reviewed
• [Journal Article] Fabrication of Cell-Adhesion Surface and Arteriole Model by Photolithography (2007)
  • Author(s): F. Arai, T. Nakano, M. Tada, Yu-Ching Lin, S. Ikeda, T. Uchida, H. Oura, T. Fukuda, T. Matsuda, M. Negoro
  • Journal Title: Journal of Robotics and Mechatronics Vol.19,No.5 Pages: 535-543
  • Peer Reviewed
• [Journal Article] Patient-Specific Blood Vessel Scaffold for Regenerative Medicine (2007)
  • Author(s): S. Ikeda, F. Arai, T. Fukuda, H. Oura, M. Negoro
  • Journal Title: 2007 IEEE International Conference on Robotics and Automation Pages: 1912-1917
  • Peer Reviewed
• [Remarks]
  • URL: http://www.biorobotics.mech.nagoya-u.ac.jp/research/research.html