内耳老廃物排泄機構に着目した新機軸脳神経臨床画像診断の確立

2019 Fiscal Year Annual Research Report

• Project/Area Number: 17H04259
• Research Institution: Nagoya University
• Principal Investigator: 長縄 慎二 名古屋大学, 医学系研究科, 教授 (50242863)
• Co-Investigator(Kenkyū-buntansha): 渡辺 宏久 藤田医科大学, 医学部, 教授 (10378177) ; 曽根 三千彦 名古屋大学, 医学系研究科, 教授 (30273238) ; 田岡 俊昭 名古屋大学, 医学系研究科, 特任教授 (30305734)
• Project Period (FY): 2017-04-01 – 2020-03-31
• Keywords: 血液脳関門 / ガドリニウム造影剤 / 磁気共鳴画像 / 血液迷路関門

Outline of Annual Research Achievements

今回の研究課題の目的である内耳老廃物排泄機構および脳老廃物排泄機構Glymphatic systemの解析を進めるために、我々が開発した液体中の極微量のガドリニウム造影剤への感度をさらに高めるための新規パルスシーケンスの臨床応用をさらに進めた。繰り返し時間の延長と反転時間の最適化、フリップアングルの増加などにより、従来よりも半分の時間で、同等のコントラストノイズ比を達成するimproved-HYDROPS(i-HYDROPS)法とi-HYDROPSの技術を応用し、さらに造影後のParadoxycal signal decreaseを防ぐための3D-real IR法を用いて、臨床例で迷路リンパ液の造影効果を検討し症例を蓄積した。
それらで症例を重ねるうちに、ガドリニウム造影剤静注後4時間にて、皮質静脈から脳脊髄液へのガドリニウム造影剤の漏れがLabbe静脈周囲や頭頂部皮質静脈周囲に頻回にみられること、そしてその漏れの程度は、年齢に相関することを見出した。初期報告で37歳を境に、若年者ではまったく漏れが見られないと報告したが、症例を重ねるうちに例外もみられたので多数例を蓄積した時点で、ROC解析を行ってカットオフ値として37.3歳が適切であることを論文発表した(Magn Reson Med Sci. 2020 Feb 6. doi: 10.2463/mrms.mp.2019-0182. )。
加齢現象の客観的な評価につながる画期的な結果として注目されている。さらにGlymphatic systemの評価のためにT1, T2などの磁気共鳴画像パラメーターを高速に定量するMR fingerprinting技術の測定精度や安定性の検証を進めるとともに、臨床データの収集をすすめ国内外の学会で発表するとともに英文論文化した（Magn Reson Med Sci, in press）。

Research Progress Status

令和元年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

令和元年度が最終年度であるため、記入しない。

Research Products

• [Journal Article] Glymphatic imaging using MRI. (2020)
  • Author(s): Toshiaki Taoka, Shinji Naganawa
  • Journal Title: J Magn Reson Imaging. Volume: 51(1) Pages: 11-24
  • DOI: 10.1002/jmri.26892.
  • Peer Reviewed / Open Access
• [Journal Article] White matter microstructural changes in tuberous sclerosis: Evaluation by neurite orientation dispersion and density imaging (NODDI) and diffusion tensor images. (2020)
  • Author(s): Toshiaki Taoka, Noriko Aida, Yuta Fujii, Kazushi Ichikawa, Hisashi Kawai, Toshiki Nakane, Rintaro Ito, Shinji Naganawa
  • Journal Title: SCIENTIFIC REPORTS Volume: 10 Pages: 436
  • DOI: 10.1038/s41598-019-57306-w.
  • Peer Reviewed / Open Access
• [Journal Article] Evaluation of newly implemented dose calculation algorithms for multileaf collimator-based CyberKnife tumor-tracking radiotherapy. (2020)
  • Author(s): Kohei Kawata, Takeshi Kamomae, Hiroshi Oguchi, Fumitaka Kawabata, Kuniyasu Okudaira, Mariko Kawamura, Kazuhiro Ohtakara, Yoshiyuki Itoh, Shinji Naganawa
  • Journal Title: Med Phys. Volume: 47(3) Pages: 1391-1403
  • DOI: 10.1002/mp.14013.
  • Peer Reviewed / Open Access
• [Journal Article] Assessing the Risk of Intracranial Aneurysm Rupture Using Morphological and Hemodynamic Biomarkers Evaluated from Magnetic Resonance Fluid Dynamics and Computational Fluid Dynamics. (2020)
  • Author(s): Roshani Perera, Haruo Isoda, Kenta Ishiguro, Takashi Mizuno, Yasuo Takehara, Masaki Terada, Chiharu Tanoi, Takehiro Naito, Harumi Sakahara, Hisaya Hiramatsu, Hiroki Namba, Takashi Izumi, Toshihiko Wakabayashi, Takafumi Kosugi, Yuki Onishi, Marcus Alley, Yoshiaki Komori, Mitsuru Ikeda, Shinji Naganawa
  • Journal Title: Magn Reson Med Sci. Volume: - Pages: -
  • DOI: 10.2463/mrms.mp.2019-0107.
  • Peer Reviewed / Open Access
• [Journal Article] Optimal Plane Selection for Measuring Post-prandial Blood Flow Increase within the Superior Mesenteric Artery: Analysis Using 4D Flow and Computational Fluid Dynamics. (2020)
  • Author(s): Masataka Sugiyama, Yasuo Takehara, Masanori Kawate, Naoki Ooishi, Masaki Terada, Haruo Isoda, Harumi Sakahara, Shinji Naganawa, Kevin M. Johnson, Oliver Wieben, Tetsuya Wakayama, Atsushi Nozaki, Hiroyuki Kabasawa
  • Journal Title: Magn Reson Med Sci. Volume: - Pages: -
  • DOI: 10.2463/mrms.mp.2019-0089.
• [Journal Article] Confirmation of Age-dependence in the Leakage of Contrast Medium around the Cortical Veins into Cerebrospinal Fluid after Intravenous Administration of Gadolinium-based Contrast Agent. (2020)
  • Author(s): Shinji Naganawa, Rintaro Ito, Hisashi Kawai, Toshiaki Taoka, Tadao Yoshida, Michihiko Sone
  • Journal Title: Magn Reson Med Sci. Volume: - Pages: -
  • DOI: 10.2463/mrms.mp.2019-0182.
  • Peer Reviewed / Open Access
• [Journal Article] Evaluation of segment 4 portal vein embolization added to right portal vein for right hepatic trisectionectomy: A retrospective propensity score-matched study. (2020)
  • Author(s): Jun Ito, Tomohiro Komada, Kojiro Suzuki, Masaya Matsushima, Masahiro Nakatochi, Yumiko Kobayashi, Tomoki Ebata, Shinji Naganawa, Masato Nagino
  • Journal Title: J Hepatobiliary Pancreat Sci. Volume: - Pages: -
  • DOI: 10.1002/jhbp.723.
• [Journal Article] Efficacy and safety of accelerated fractionated radiotherapy without elective nodal irradiation for T3N0 glottic cancer without vocal cord fixation. (2020)
  • Author(s): Masayuki Okumura, Atsushi Motegi, Sadamoto Zenda, Naoki Nakamura, Hidehiro Hojo, Masaki Nakamura, Yasuhiro Hirano, Shun-Ichiro Kageyama, Satoko Arahira, Raturi Vijay Parshuram, Hirofumi Kuno, Ryuichi Hayashi, Makoto Tahara, Yoshiyuki Itoh , Shinji Naganawa, Tetsuo Akimoto
  • Journal Title: Head Neck. Volume: - Pages: -
  • DOI: 10.1002/hed.26092.
  • Peer Reviewed
• [Journal Article] Pharmacologic and non-pharmacologic interventions to prevent hypersensitivity reactions of non-ionic iodinated contrast media: a systematic review protocol. (2020)
  • Author(s): Hiroyasu Umakoshi, Takashi Nihashi, Hironori Shimamoto, Takehiro Yamada, Hiroaki Ishiguchi, Akira Takada, Naoki Hirasawa, Shunichi Ishihara, Yasuo Takehara, Shinji Naganawa, Matthew Davenport, Teruhiko Terasawa,
  • Journal Title: BMJ Open. 1 Volume: 10(3) Pages: e033023.
  • DOI: 10.1136/bmjopen-2019-033023.
  • Peer Reviewed / Open Access
• [Journal Article] Age Dependence of Gadolinium Leakage from the Cortical Veins into the Cerebrospinal Fluid Assessed with Whole Brain 3D-real Inversion Recovery MR Imaging. (2019)
  • Author(s): Shinji Naganawa, Toshiki Nakane, Hisashi Kawai, Toshiaki Taoka
  • Journal Title: Magn Reson Med Sci. Volume: 18(2) Pages: 163-169
  • DOI: 10.2463/mrms.mp.2018-0053.
  • Peer Reviewed / Open Access
• [Journal Article] The Space between the Pial Sheath and the Cortical Venous Wall May Connect to the Meningeal Lymphatics. (2019)
  • Author(s): Shinji Naganawa, Rintaro Ito, Toshiaki Taoka, Tadao Yoshida, Michihiko Sone
  • Journal Title: Magn Reson Med Sci. Volume: 19(1) Pages: 1-4
  • DOI: 10.2463/mrms.bc.2019-0099.
  • Peer Reviewed / Open Access
• [Journal Article] Detection of IV-gadolinium Leakage from the Cortical Veins into the CSF Using MR Fingerprinting. (2019)
  • Author(s): Shinji Naganawa, Toshiki Nakane, Hisashi Kawai, Toshiaki Taoka, Hirokazu Kawaguchi, Katsuya Maruyama, Katsutoshi Murata, Gregor Korzdorfer, Josef Pfeuffer, Mathias Nittka, Michihiko Sone
  • Journal Title: Magn Reson Med Sci. Volume: - Pages: -
  • DOI: 10.2463/mrms.mp.2019-0048.
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Celebrating the beginning of international journal collaboration. (2019)
  • Author(s): Shinji Naganawa, Yukunori Korogi
  • Journal Title: Jpn J Radiol. Volume: 38(1) Pages: 1-2
  • DOI: 10.1007/s11604-019-00904-5.
  • Peer Reviewed / Open Access
• [Journal Article] Increased signal intensity of low-concentration gadolinium contrast agent by longer repetition time in heavily T2 weighted ;FLAIR. (2019)
  • Author(s): Yutaka Kato, Kiminori Bokura, Toshiaki Taoka, Shinji Naganawa
  • Journal Title: Jpn J Radiol Volume: 37(5) Pages: 431-435
  • DOI: 10.1007/s11604-019-00828-0.
  • Peer Reviewed / Open Access
• [Journal Article] A case of human pancreatic eurytremiasis. (2019)
  • Author(s): Hiroshi Ogawa, Yasuo Takehara, Shinji Naganawa, Junpei Yamaguchi, Masato Nakaguro
  • Journal Title: Otol Neurotol. Volume: 44(4) Pages: 1213-1216
  • DOI: 10.1007/s00261-019-01925-4.
  • Peer Reviewed / Open Access
• [Journal Article] Utility of Metabolic Parameters on FDG PET/CT in the Classification of Early-Stage Lung Adenocarcinoma: Prediction of Pathological Invasive Size. (2019)
  • Author(s): Shingo Iwano, Shinji Ito, Shinichiro Kamiya, Rintaro Ito, Katsuhiko Kato, Shinji Naganawa
  • Journal Title: Clin Nucl Med. Volume: 44(7) Pages: 560-565
  • DOI: 10.1097/RLU.0000000000002591.
  • Peer Reviewed / Open Access
• [Journal Article] Postoperative recurrence of clinical early-stage non-small cell lung cancers: a comparison between solid and subsolid nodules. (2019)
  • Author(s): Shingo Iwano, Hiroyasu Umakoshi, Shinichiro Kamiya, Kohei Yokoi, Koji Kawaguchi, Takayuki Fukui, Shinji Naganawa
  • Journal Title: Cancer Imaging. Volume: 19(1) Pages: 33
  • DOI: 10.1186/s40644-019-0219-3.
  • Peer Reviewed / Open Access
• [Journal Article] Balloon-Occluded Retrograde Transvenous Obliteration for Fundal Gastric Variceal Bleeding in a Small Child. (2019)
  • Author(s): Tomohiro Komada, Kojiro Suzuki, Kazuo Oshima, Masaya Matsushima, Ken Nagasaka, Shinji Naganawa
  • Journal Title: J Vasc Interv Radiol. Volume: 30(10) Pages: 1624-1625
  • DOI: 10.1016/j.jvir.2019.06.022.
  • Peer Reviewed / Open Access
• [Journal Article] Reorganization of brain networks and its association with general cognitive performance over the adult lifespan. (2019)
  • Author(s): Epifanio Bagarinao, Hirohisa Watanabe, Satoshi Maesawa, …他 Daisuke Mori, Haruo Isoda, Shinji Naganawa, Gen Sobue
  • Journal Title: Sci Rep. Volume: 9(1) Pages: 11352
  • DOI: 10.1038/s41598-019-47922-x.
  • Peer Reviewed / Open Access
• [Journal Article] A plea for systematic literature analysis and conclusive study design, comment on: "Systematic review of magnetic resonance imaging for diagnosis of Meniere disease". (2019)
  • Author(s): Robert Gurkov, Krisztina Barath, Bert de Foer, Munehisa Fukushima, Michael Gluth, Jermy Hornibrook, Nicolas Perez-Fernandez, Ilmari Pyykko, Michihiko Sone, Shin-Ichi Usami, Wuqing Wang, Jing Zou, Shinji Naganawa
  • Journal Title: J Vestib Res. Volume: - Pages: -
  • DOI: 10.3233/VES-190662.
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Large expert-curated database for benchmarking document similarity detection in biomedical literature search. (2019)
  • Author(s): Peter Brown, RELISH Consortium, Yaoqi Zhou,…RELISH consortium (Shinji Naganawa)
  • Journal Title: DATABASE (The Journal of Biological Databeses and Curation) Volume: - Pages: 085
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] High-dose-rate intracavitary brachytherapy for recurrent cervical cancer in the vaginal stump after hysterectomy. (2019)
  • Author(s): Yuka Kozai, Yoshiyuki Itoh, Mariko Kawamura, Rie Nakahara, Junji Ito, Tohru Okada, Fumitaka Kikkawa, Mitsuru Ikeda, Shinji Naganawa
  • Journal Title: Nagoya J Med Sci Volume: 81(3) Pages: 351-358
  • DOI: 10.18999/nagjms.81.3.351.
  • Peer Reviewed / Open Access
• [Journal Article] Phase II study of chemoradiotherapy combined with gemcitabine plus nab-paclitaxel for unresectable locally advanced pancreatic ductal adenocarcinoma (NUPAT 05 Trial): study protocol for a single arm phase II study. (2019)
  • Author(s): Nao Takano, Suguru Yamada, Akihiro Hirakawa, Yukihiro Yokoyama,Yoshiki Hirooka, Yoshiyuki Ito, Shinji Naganawa, Yuichi Ando, …他 Masato Nagino, Hidemi Goto, Tsutomu Fujii, Yasuhiro Kodera
  • Journal Title: Nagoya J Med Sci. Volume: 81(2) Pages: 233-239
  • DOI: 10.18999/nagjms.81.2.233.
  • Peer Reviewed / Open Access
• [Journal Article] Whole abdominopelvic intensity-modulated radiation therapy for peritoneal disseminated rhabdomyosarcoma with three-year follow-up: a case report. (2019)
  • Author(s): Mariko Kawamura, Kuniyasu Okudaira, Yoshiyuki Itoh, Takeshi Kamomae, Eri Nishikawa, Hideki Muramatsu, Yoshiyuki Takahashi, Kazuki Yokota, Shinji Naganawa
  • Journal Title: Radiat Oncol. Volume: 14(1) Pages: 127
  • DOI: 10.1186/s13014-019-1333-x.
  • Peer Reviewed / Open Access
• [Journal Article] Comprehensive Evaluation of B1 +-corrected FISP-based Magnetic Resonance Fingerprinting: Accuracy, Repeatability and Reproducibility of T1 and T2 Relaxation Times for ISMRM/NIST System Phantom and Volunteers. (2019)
  • Author(s): Yutaka Kato, Kazushige Ichikawa, Kuniyasu Okudaira, Toshiaki Taoka, Hirokazu Kawaguchi, Katsutoshi Murata, Katsuya Maruyama, Gregor Koerzdoerfer, Josef Pfeuffer, Mathias Nittka, Shinji Naganawa
  • Journal Title: Magn Reson Med Sci. Volume: - Pages: -
  • DOI: 10.2463/mrms.mp.2019-0016.
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Quantification of Endolymphatic Space Volume after Intravenous Administration of a Single Dose of Gadolinium-based Contrast Agent: 3D-real Inversion Recovery versus HYDROPS-Mi2. (2019)
  • Author(s): Toshio Ohashi, Shinji Naganawa, Ai Takeuchi, Toshio Katagiri, Kayao Kuno
  • Journal Title: Magn Reson Med Sci. Volume: - Pages: -
  • DOI: 10.2463/mrms.mp.2019-0013.
  • Peer Reviewed / Open Access
• [Journal Article] Monitoring of fatigue in radiologists during prolonged image interpretation using fNIRS. (2019)
  • Author(s): Takashi Nihashi, Takeo Ishigaki, Hiroko Satake, Shinji Ito, Osamu Kaii, Yoshine Mori, Kazuhiro Shimamoto, Hiromichi Fukushima, Kojiro Suzuki, Hiroyasu Umakoshi, Mitsuo Ohashi, Fumio Kawaguchi, Shinji Naganawa
  • Journal Title: Jpn J Radiol. Volume: 37(6) Pages: 437-448
  • DOI: 10.1007/s11604-019-00826-2.
  • Peer Reviewed / Open Access
• [Presentation] 肝原発MALTリンパ腫の2例 (2020)
  • Author(s): 西田あゆみ、兵藤良太、岩野信吾、下山芳江、長縄慎二
  • Organizer: 第87回東海総合画像医学研究会
• [Presentation] 乳房専用PETにおける正常乳腺のFDG集積に対する閉経の有無と月経周期の影響 (2020)
  • Author(s): 清水友理、佐竹弘子、石垣聡子、長縄慎二、田所匡典、石口恒男
  • Organizer: 日本医学放射線学会第167回中部地方会
• [Presentation] IGBT導入に向けたコンツール制度の検証： high volume centerでの導入に向けて (2020)
  • Author(s): 川村麻里子、伊藤善之、大宝和博、伊藤淳二、中原理絵、大家祐実、香西由加、髙瀬裕樹、加茂前健、長縄慎二
  • Organizer: 日本医学放射線学会第167回中部地方会
• [Presentation] Meniere disease imaging: What is right, what is wrong, what is new (2019)
  • Author(s): Shinji Naganawa
  • Organizer: The 32nd Annual Meeting of the European Society of Head and Neck Radiology (eshnr 2019)
  • Int'l Joint Research / Invited
• [Presentation] Influence of implanted metals in new CT reconstruction algorithm for radiotherapy treatment planning. (2019)
  • Author(s): Takeshi Kamomae, Takayoshi Nakaya, Fumitaka Kawabata, Kuniyasu Okudaira, Motoki Kumagai, Hiroshi Oguchi, Yoshiyuki Itoh, Shinji Naganawa
  • Organizer: European Society for Therapeutic Radiology and Oncology (ESTRO38)
  • Int'l Joint Research
• [Presentation] The impact of shorter acquisition time in MRF: Long term repeatability and reproducibility study on ISMRM/NIST phantom and volunteers. (2019)
  • Author(s): Yutaka Kato, Kazushige Ichikawa, Toshiaki Taoka, Hirokazu Kawaguchi, Katsutoshi Murata, Katsuya Maruyama, Gregor Koerzdoerfer, Josef Pfeuffer, Mathias Nittka, Shinji Naganawa
  • Organizer: International Society for Magnetic Resonance in Medicine 27th Annual Meeting (27th ISMRM)
  • Int'l Joint Research
• [Presentation] Low b-value diffusion weighted imaging to evaluate cerebrospinal fluid dynamics. (2019)
  • Author(s): Toshiaki Taoka, Shinji Naganawa, Hisashi Kawai, Toshiki Nakane, Katsutoshi Murata
  • Organizer: International Society for Magnetic Resonance in Medicine 27th Annual Meeting (27th ISMRM)
  • Int'l Joint Research
• [Presentation] Evaluation of 223Ra therapy on bone metastases of prostate cancer by 18F-fluoride PET/CT, 18F-FDG PET/CT and bone scintigraphy/SPECT (2019)
  • Author(s): Katsuhiko Kato, Tetsuro Odagawa, Naotoshi Fujita, Yoshinori Tsutsumi, Shinji Abe, Shinji Naganawa
  • Organizer: Society of Nuclear Medicine & Molecular Imaging 2019 Annual Meeting
  • Int'l Joint Research
• [Presentation] Development of Three-Dimensional Printed Compensator for Improvement of Dose Distribution in Boron Neutron Capture Therapy: A Preliminary Study (2019)
  • Author(s): Takeshi Kamomae, Yoshinori Sakurai, Masataka Oita, Takushi Takata, Tatsuya Niimi, Takashi Matsumura, Takuya Saito, Tomohiro Komada, Katsuhiko Kato, Yoshiyuki Itoh, Shinji Naganawa
  • Organizer: 61st American Association of Physicists in Medicine Annual Meeting
  • Int'l Joint Research
• [Presentation] An attempt to create a hollow blood vessel model by direct inkjet 3D printing with nano-composite hydrogel for IR. (2019)
  • Author(s): Tomohiro Komada, Takeshi Kamomae, Takashi Matsumura, Takuya Saito, Tatsuya Niimi, Masaya Matsushima, Ryota Hyodo, Shinji Naganawa
  • Organizer: Cardiovascular and Interventional Radiological Society of Europe 2019
  • Int'l Joint Research
• [Presentation] Should Small Cell Carcinoma of the Cervix be Treated As Localized Small Cell Cancer or Advanced Cervical Cancer: A Retrospective Multi-Institutional Cohort Study (2019)
  • Author(s): Mariko Kawamura, Yutaro Koide, Taro Murai, Shunichi Ishihara, Yuuki Takase, Takayuki Murao, Dai Okazaki, Takahiro Yamaguchi, Kaoru Uchiyama, Yoshiyuki Itoh, Takeshi Kodaira, Yuta Shibamoto, Mika Mizuno, Fumitaka Kikkawa, Shinji Naganawa
  • Organizer: American Society for Radiation Oncology 2019(ASTRO 2019)
  • Int'l Joint Research
• [Presentation] Clinical results of T1 glottic cancer treated with radiotherapy using 2.25 Gy per fractions：A multicenter survey in clinical practice. (2019)
  • Author(s): Yumi Oie,Yoshiyuki Itoh, Mariko Kawamura, Yuki Takase, Takayuki Murano, Shunichi Ishihara, Yoshihito Nomoto, naoki Hirasawa, Akiko Asano, Kouji Yamakawa, Junji Ito, Shinji Naganawa
  • Organizer: American Society for Radiation Oncology 2019(ASTRO 2019)
  • Int'l Joint Research
• [Presentation] MR Fingerprinting Evaluation for the Early Changes of Relaxation Time in the Brain Tumor and Surrounding White Matter After Stereotactic Radiotherapy. (2019)
  • Author(s): Toshiaki Taoka, Kazuhiro Ohtakara, Hisashi Kawai, Yutaka Kato, Yoshiyuki Itoh, Shinji Naganawa, Toshiki Nakane, Rintaro Ito, Kazushige Ichikawa, Kuniyasu Okudaira, Katsutoshi Murata, Katsuya Maruyama, Hirokazu Kawaguchi, Gregor Koerzdoerfer, Josef Pfeuffer, Mathias Nittka
  • Organizer: 105th Scientific Assembly and Annual Meeting of Radiological Society of North America(RSNA)
  • Int'l Joint Research
• [Presentation] Gadolinium Deposition in the Brain and Glymphatic System (2019)
  • Author(s): Toshiaki Taoka, Rintaro Ito, Rei Nakamichi, Toshiki Nakane, Hisashi Kawai, Shinji Naganawa
  • Organizer: 105th Scientific Assembly and Annual Meeting of Radiological Society of North America(RSNA)
  • Int'l Joint Research
• [Presentation] Invited Lecture 10の司会 (2019)
  • Author(s): 長縄慎二
  • Organizer: 第78回日本医学放射線学会総会
• [Presentation] MR imaging of endolymphatic hydrops; What is right, what is wrong, and what is new. (2019)
  • Author(s): 長縄慎二
  • Organizer: 第21回山形めまい研究会
• [Presentation] 特別講演Ⅱ 脳の老廃物排泄機構とMRI (2019)
  • Author(s): 長縄慎二
  • Organizer: 第11回お茶の水 Neuroimaging Conference-ONIC-
• [Presentation] Glymphatic systemとMRI造影剤 (2019)
  • Author(s): 長縄慎二
  • Organizer: 第47回日本磁気共鳴医学会大会
• [Presentation] Glymphatic systemとMRI (2019)
  • Author(s): 長縄慎二
  • Organizer: 第99回慶應医学会総会・シンポジウム
• [Presentation] 特別講演 Glymphatic SystemとMRI (2019)
  • Author(s): 長縄慎二
  • Organizer: 画論 27th The Best Image
• [Presentation] Novel electron density based-CT image from single-and dual-energy scanning for radiation therapy treatment planning. (2019)
  • Author(s): Takeshi Kamomae, Fumitaka Kawabata, Takayoshi Nakaya, Kuniyasu Okudaira, Motoki Kumagai, Yoshikazu Miyake, Hiroshi Oguchi, Yoshiyuki Itoh, Shinji Naganawa
  • Organizer: 第117回日本医学物理学会学術大会
• [Presentation] Comparison single treatment planning and multiple planning for multiple targets in Cyberknife therapy. (2019)
  • Author(s): Motoki Kumagai, Kazuhiro Ohtakara, Takeshi Kamomae, Fumitaka Kawabata, Kuniyasu Okudaira, Yoshiyuki Itoh, Shinji Naganawa
  • Organizer: 第117回日本医学物理学会学術大会
• [Presentation] 感染契機の肺動脈仮性動脈瘤からの喀血に対し塞栓術を施行した1例 A case of embolization for hemoptysis due to an infectious pulmonary artery pseudoaneurysm. (2019)
  • Author(s): 山田恵一郎、兵藤良太、堀口瞭太、伊藤 準、松島正哉、駒田智大、長縄慎二、進藤有一郎、長坂 憲
  • Organizer: 第48回日本IVR学会総会
• [Presentation] 舌骨下やリンパ節へのI-131集積は分化型甲状腺癌患者に対する低用量アブレーションの成否に影響するか） (2019)
  • Author(s): 伊藤信嗣、岩野信吾、長縄慎二、加藤克彦
  • Organizer: 日本核医学会 第89回中部地方会
• [Presentation] 肝内門脈静脈短絡に対し塞栓術を施行した2例 (2019)
  • Author(s): 松島正哉、駒田智大、山田恵一郎、堀口瞭太、伊藤 準、兵藤良太、岩野信吾、長縄慎二、石津洋二、田中 卓、馬越弘泰
  • Organizer: 第66回中部IVR研究会
• [Presentation] 術前診断が困難であった膵lymphangiomaの1例 (2019)
  • Author(s): 小川 浩、竹原康雄、長縄慎二、高見秀樹、中黒匡人
  • Organizer: 日本医学放射線学会第166回中部地方会
• [Presentation] 早期乳癌に対する乳房温存手術＋術中放射線部分照射：10年の結果 (2019)
  • Author(s): 川村麻里子、伊藤善之、大宝和博、岡田 徹、伊藤淳二、大家祐実、加茂前健、長縄慎二
  • Organizer: 日本医学放射線学会第166回中部地方会
• [Presentation] 中枢神経系原発anaplastic lymphoma kinase陽性未分化大細胞リンパ腫の1例 (2019)
  • Author(s): 佐々木裕太郎、中道玲瑛、川井 恒、田岡俊昭、長縄慎二、川島直実、下山芳江
  • Organizer: 第86回東海総合画像医学研究会
• [Presentation] 7テスラMR装置の高空間分解能3次元位相コントラスト磁気共鳴法を利用した脳血流動態解析の精度検証 (2019)
  • Author(s): 田嶋駿亮、礒田治夫、福永雅喜、小森芳秋、Roshani Perera、水野 崇、定藤規弘、長縄慎二
  • Organizer: 第86回東海総合画像医学研究会
• [Presentation] 腹部大動脈に対するEndovascular Aneurysmal Repairは内臓動脈の血流を増加させる(4D-Flowによる血行動態解析) (2019)
  • Author(s): 杉山将隆、竹原康雄、堀口瞭太、兵藤良太、駒田智大、長縄慎二、礒田治夫、牛尾貴輔、五島 聡、若山哲也、野崎 敦、Marcus Alley
  • Organizer: 第1回 4D-Flow研究会
• [Presentation] 健常者とEVAR術前後の腹部大動脈瘤患者のEnergy Loss (2019)
  • Author(s): 水野 崇、竹原康雄、杉山将隆、堀口瞭太、長縄慎二、櫻井康雄、加藤 裕、阿部真治、礒田治夫、佐藤智宏、石口恒男、田所匡典、野崎 敦
  • Organizer: 第1回 4D-Flow研究会
• [Presentation] 腹部大動脈瘤に対するステントグラフト内挿術(EVAR) (2019)
  • Author(s): 堀口瞭太、竹原康雄、杉山将隆、兵藤良太、駒田智大、松島正哉、川井 恒、長縄慎二、水野 崇、櫻井康雄、阿部真治、小森芳秋
  • Organizer: 第1回 4D-Flow研究会
• [Presentation] 定位放射線治療後の組織緩和時間のMRFによる測定：標的領域と周辺領域の評価 MR fingerprinting evaluation for the early changes of relaxation time in the target area and surrounding area after stereotactic radiotherapy. (2019)
  • Author(s): 田岡俊昭、大宝和博、川井 恒、中根俊樹、伊藤倫太郎、加藤 裕、市川和茂、奥平訓康、伊藤善之、川口浩和、村田勝俊、丸山克也、 Gregor Koerzdoerfer, Josef Pfeuffer, Mathias Nittka, 長縄慎二
  • Organizer: 第47回日本磁気共鳴医学会大会
• [Presentation] Evaluation of number of iterations for reconstruction in VIBE with compressed sensing on ultrafast dynamic breast MR Compressed sensing VIBE法を用いた乳房ultrafast MRIにおけるiteration回数による画質への影響 (2019)
  • Author(s): 河村美奈子、加藤 裕、奥平訓康、佐竹弘子、丸山克也、長縄慎二
  • Organizer: 第47回日本磁気共鳴医学会大会
• [Presentation] Impact of step size in the dictionary for long T1 values on MR Fingerprinting MR Fingerprintingにおけるステップ幅の異なる辞書による定量値への影響 (2019)
  • Author(s): 熊澤智宇、加藤 裕、市川和茂、田岡俊昭、村田勝俊、丸山克也、Gregor Koerzdoerfer, Josef Pfeuffer, Mathias Nittka, 長縄慎二
  • Organizer: 第47回日本磁気共鳴医学会大会
• [Presentation] 分化型甲状腺癌の術後アブレーションにおける予期せぬトレーサー集積部位の検討 (2019)
  • Author(s): 岩野信吾、伊藤信嗣、伊藤倫太郎、神谷晋一朗、加藤克彦、長縄慎二
  • Organizer: 日本核医学会第59回学術集会
• [Presentation] 舌骨下やリンパ節へのI-131集積は低用量アブレーションの成否に影響するか (2019)
  • Author(s): 伊藤信嗣、岩野信吾、加藤克彦、長縄慎二
  • Organizer: 日本核医学会第59回学術集会
• [Presentation] 18F-NaF PET/CT、18F-FDG PET/CT、骨シンチ/SPECTによる去勢抵抗性前立腺癌骨転移223Ra治療の評価 (2019)
  • Author(s): 加藤克彦、小田川哲郎、藤田尚利、堤 貴紀、田村美香、阿部真治、長谷川 千夏、長縄慎二
  • Organizer: 日本核医学会第59回学術集会
• [Remarks] 名古屋大学医学部放射線医学教室ホームページ
  • URL: https://www.med.nagoya-u.ac.jp/rad/