Study on Multi-photon gamma-ray coincidence tomography

2021 Fiscal Year Annual Research Report

• Project/Area Number: 17H06159
• Research Institution: The University of Tokyo
• Principal Investigator: 高橋 浩之 東京大学, 大学院工学系研究科(工学部), 教授 (70216753)
• Co-Investigator(Kenkyū-buntansha): 百瀬 敏光 国際医療福祉大学, 医学部, 教授 (20219992) ; 羽場 宏光 国立研究開発法人理化学研究所, 仁科加速器科学研究センター, 室長 (60360624) ; 鎌田 圭 東北大学, 未来科学技術共同研究センター, 准教授 (60639649) ; 島添 健次 東京大学, 大学院工学系研究科(工学部), 特任准教授 (70589340)
• Project Period (FY): 2017-05-31 – 2022-03-31
• Keywords: In-111 / コンプトンカメラ / カスケードガンマ線 / CeBr3 / 核医学イメージング / 同時計数

Outline of Annual Research Achievements

今年度はSOIの大面積型検出器を用いた電子飛跡精密計測カメラの開発を進め、大型素子のCMOS-SOIチップの製作を行い、15.3mm×24.6mmのダイサイズで36μm角のピクセルサイズ、384 ×608ピクセルのCMOS-SOIチップを開発した。Am-241、Co-57、Cd-109、Ba-133などのガンマ線源を用いたエネルギースペクトル取得試験を行い、低いガンマ線エネルギーに対しても10%程度のエネルギー分解能が得られた。また、反跳電子の飛跡を記録し読み出すことができた。東北大学において製作したシンチレータアレイと組み合わせたモジュールの製作を進め、CeBr3読出用の高速ASICを開発し、基盤に実装し、ToT(Time over Threshold)法によるディジタル信号出力の読み出しにより、時間分解能として40ピコ秒および良好なエネルギー分解能と線形性を有する性能を持つことを確認した。1チップに64チャネルを搭載しており8×8ピクセルのシンチレータと組み合わせて、性能評価を行った。この結果、Na-22線源を用いて、2個のCeBr3アレイ間の同時計数における時間分解能は293ps(FWHM)であった。また、2個のCeBr3アレイを用いてコンプトンカメラを構成し、動作を確認した結果、空間分解能3.1mm FWHMの値が得られた。
DPECT撮像を実施し、In-111で標識したペプチドを投与したマウスのDPECTイメージングを国際医療福祉大学と東京大学で協力して実施し、神経内分泌腫瘍のイメージングに成功した。
理化学研究所においては、理研AVFサイクロトロンにおいて候補として見出したK-43, Cr-48などの2光子放出核種に加え、新たにCu-67の製造試験を行い、ファントムを用いたIn-111とCu-67の同時撮像を実施した結果、これらを分離して計測することができた。

Research Progress Status

令和3年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

令和3年度が最終年度であるため、記入しない。

Research Products

• [Journal Article] Imaging and sensing of pH and chemical state with nuclear-spin-correlated cascade gamma rays via radioactive tracer (2022)
  • Author(s): Shimazoe Kenji、Uenomachi Mizuki、Takahashi Hiroyuki
  • Journal Title: Communications Physics Volume: 5 Pages: -
  • DOI: 10.1038/s42005-022-00801-w
  • Peer Reviewed / Open Access
• [Journal Article] A Novel Proposal for an Index for Regional Cerebral Perfusion Pressure ? A Theoretical Approach Using Fluid Dynamics (2022)
  • Author(s): Kameyama Masashi、Momose Toshimitsu、Ishibashi Kenji、Ishii Kenji
  • Journal Title: Frontiers in Neurology Volume: 12 Pages: -
  • DOI: 10.3389/fneur.2021.765463
  • Peer Reviewed
• [Journal Article] Production cross sections of 47Sc via alpha-particle-induced reactions on natural calcium up to 29?MeV (2022)
  • Author(s): Aikawa Masayuki、Hanada Yukina、Ichinkhorloo Dagvadorj、Haba Hiromitsu、Tak?cs S?ndor、Ditr?i Ferenc、Sz?cs Zolt?n
  • Journal Title: Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms Volume: 515 Pages: 1～6
  • DOI: 10.1016/j.nimb.2022.01.008
  • Peer Reviewed
• [Journal Article] Anion- and cation-exchange studies of Zr, Hf, and Th using ion-exchange resin and fiber in H2SO4 media for chemical characterization of sulfate complex of Rf (2022)
  • Author(s): Yokokita Takuya、Yano Shinya、Komori Yukiko、Haba Hiromitsu
  • Journal Title: Journal of Radioanalytical and Nuclear Chemistry Volume: 331 Pages: 1127～1134
  • DOI: 10.1007/s10967-021-08184-y
• [Journal Article] Simultaneous in vivo imaging with PET and SPECT tracers using a Compton-PET hybrid camera (2021)
  • Author(s): Uenomachi Mizuki、Takahashi Miwako、Shimazoe Kenji、Takahashi Hiroyuki、Kamada Kei、Orita Tadashi、Ogane Kenichiro、Tsuji Atsushi B.
  • Journal Title: Scientific Reports Volume: 11 Pages: -
  • DOI: 10.1038/s41598-021-97302-7
  • Peer Reviewed / Open Access
• [Journal Article] Simultaneous measurements of single gamma ray of 131I and annihilation radiation of 18F with Compton PET hybrid camera (2021)
  • Author(s): Ogane Kenichiro、Uenomachi Mizuki、Shimazoe Kenji、Takahashi Miwako、Takahashi Hiroyuki、Seto Yasuyuki、Momose Toshimitsu
  • Journal Title: Applied Radiation and Isotopes Volume: 176 Pages: 109864～109864
  • DOI: 10.1016/j.apradiso.2021.109864
  • Peer Reviewed / Open Access
• [Journal Article] A design of forceps-type coincidence radiation detector for intraoperative LN diagnosis: clinical impact estimated from LNs data of 20 esophageal cancer patients (2021)
  • Author(s): Takahashi Miwako、Yoshimura Shuntaro、Takyu Sodai、Aikou Susumu、Okumura Yasuhiro、Yagi Koichi、Fukayama Masashi、Momose Toshimitsu、Seto Yasuyuki、Yamaya Taiga
  • Journal Title: Annals of Nuclear Medicine Volume: 36 Pages: 285～292
  • DOI: 10.1007/s12149-021-01701-9
  • Peer Reviewed
• [Journal Article] 2.Crystal growth and optical properties of Ce-doped (La,Y) 2Si2O7 single crystal (2021)
  • Author(s): Takahiko Horiai, Juraj Paterek, Jan Pejchal, Marketa Jarosova, Jan Rohlicek, Shunsuke Kurosawa, Takashi Hanada, Masao Yoshino, Akihiro Yamaji, Satoshi Toyoda, Hiroki Sato, Yuji Ohashi, Kei Kamada, Yuui Yokota, Akira Yoshikawa, Martin Nikl
  • Journal Title: Journal of Crystal Growth Volume: 572 Pages: -
  • Peer Reviewed
• [Journal Article] Luminescence and scintillation properties of Gd3Sc2(Al3-xGax)O12:Ce (x = 1, 2, 3) garnet crystals (2021)
  • Author(s): Chewpraditkul Warut、Pattanaboonmee Nakarin、Chewpraditkul Weerapong、Sakthong Ongsa、Kim Kyoung Jin、Yoshino Masao、Horiai Takahito、Kurosawa Shunsuke、Yoshikawa Akira、Kamada Kei、Drozdowski Winicjusz、Witkowski Marcin E.、Makowski Micha?、Kucerkova Romana、Nikl Martin
  • Journal Title: Radiation Physics and Chemistry Volume: 187 Pages: 109559～109559
  • DOI: 10.1016/j.radphyschem.2021.109559
  • Peer Reviewed
• [Journal Article] Development of the Multi-Cubic <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline" id="d1e1511" altimg="si65.svg"><mml:mi>γ</mml:mi></mml:math>-ray spectrometer and its performance under intense 137Cs and 60Co radiation fields (2021)
  • Author(s): Kaburagi Masaaki、Shimazoe Kenji、Kato Masahiro、Kurosawa Tadahiro、Kamada Kei、Kim Kyoung Jin、Yoshino Masao、Shoji Yasuhiro、Yoshikawa Akira、Takahashi Hiroyuki
  • Journal Title: Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment Volume: 1010 Pages: 165544～165544
  • DOI: 10.1016/j.nima.2021.165544
  • Peer Reviewed
• [Journal Article] Structural analyses of Gd3(Al,Ga)5O12 garnet solid solutions via X-ray and UV absorption spectroscopy experiments for Gd atoms (2021)
  • Author(s): Kitaura Mamoru、Kamada Kei、Ina Toshiaki、Yamane Hisanori、Ishizaki Manabu、Watanabe Shinta、Azuma Junpei、Yamamoto Isamu、Ohnishi Akimasa、Usuki Takeshi
  • Journal Title: Journal of Alloys and Compounds Volume: 867 Pages: 159055～159055
  • DOI: 10.1016/j.jallcom.2021.159055
  • Peer Reviewed
• [Journal Article] Investigation of Crystal Shape Controllability in the Micro-Pulling-Down Method for Low-Wettability Systems (2021)
  • Author(s): Murakami Rikito、Oikawa Katsunari、Kamada Kei、Yoshikawa Akira
  • Journal Title: ACS Omega Volume: 6 Pages: 8131～8141
  • DOI: 10.1021/acsomega.0c05913
  • Peer Reviewed
• [Journal Article] First imaging demonstration of a crosshair light-sharing PET detector (2021)
  • Author(s): Yoshida Eiji、Akamatsu Go、Tashima Hideaki、Kamada Kei、Yoshikawa Akira、Yamaya Taiga
  • Journal Title: Physics in Medicine &amp; Biology Volume: 66 Pages: 065013～065013
  • DOI: 10.1088/1361-6560/abe839
  • Peer Reviewed
• [Journal Article] Activation cross sections of proton-induced reactions on praseodymium up to 30?MeV (2021)
  • Author(s): Aikawa Masayuki、Hanada Yukina、Huang He、Haba Hiromitsu
  • Journal Title: Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms Volume: 508 Pages: 29～33
  • DOI: 10.1016/j.nimb.2021.10.006
• [Journal Article] Production of $$^{178}$$Hfm2 and a simple chemical separation method for Hf recovery (2021)
  • Author(s): Kitamura Noritaka、Imai Nobuaki、Haba Hiromitsu、Michimasa Shin’ichiro、Shimoura Susumu、Yamaguchi Yuki
  • Journal Title: Journal of Radioanalytical and Nuclear Chemistry Volume: 330 Pages: 721～725
  • DOI: 10.1007/s10967-021-08032-z
• [Journal Article] Cross section measurement of alpha-particle-induced reactions on natSb (2021)
  • Author(s): Tak?cs S.、Ditr?i F.、Sz?cs Z.、Brezovcsik K.、Haba H.、Komori Y.、Aikawa M.、Saito M.、Murata T.、Sakaguchi M.、Ukon N.
  • Journal Title: Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms Volume: 505 Pages: 24～33
  • DOI: 10.1016/j.nimb.2021.08.008
• [Journal Article] Activation cross section measurement of alpha-particle induced reactions on natural neodymium (2021)
  • Author(s): Sakaguchi Michiya、Aikawa Masayuki、Ukon Naoyuki、Komori Yukiko、Haba Hiromitsu、Otuka Naohiko、Tak?cs S?ndor
  • Journal Title: Applied Radiation and Isotopes Volume: 176 Pages: 109826～109826
  • DOI: 10.1016/j.apradiso.2021.109826
• [Journal Article] Stabilization of an ²¹¹At-Labeled Antibody with Sodium Ascorbate (2021)
  • Author(s): Manabe Shino、Takashima Hiroki、Ohnuki Kazunobu、Koga Yoshikatsu、Tsumura Ryo、Iwata Nozomi、Wang Yang、Yokokita Takuya、Komori Yukiko、Usuda Sachiko、Mori Daiki、Haba Hiromitsu、Fujii Hirofumi、Yasunaga Masahiro、Matsumura Yasuhiro
  • Journal Title: ACS Omega Volume: 6 Pages: 14887～14895
  • DOI: 10.1021/acsomega.1c00684
• [Journal Article] Production cross sections of dysprosium, terbium and gadolinium radioisotopes from the alpha-particle-induced reactions on natural gadolinium up to 50?MeV (2021)
  • Author(s): Ichinkhorloo Dagvadorj、Aikawa Masayuki、Tsoodol Zolbadral、Murata Tomohiro、Sakaguchi Michiya、Komori Yukiko、Yokokita Takuya、Haba Hiromitsu
  • Journal Title: Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms Volume: 499 Pages: 46～52
  • DOI: 10.1016/j.nimb.2021.04.018
  • Peer Reviewed
• [Journal Article] Activation cross sections of deuteron-induced reactions on praseodymium up to 24?MeV (2021)
  • Author(s): Aikawa Masayuki、Maehashi Takuto、Ichinkhorloo Dagvadorj、Ebata Shuichiro、Komori Yukiko、Haba Hiromitsu
  • Journal Title: Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms Volume: 498 Pages: 23～26
  • DOI: 10.1016/j.nimb.2021.04.011
  • Peer Reviewed
• [Journal Article] Image reconstruction method for dual-isotope positron emission tomography (2021)
  • Author(s): Fukuchi T.、Shigeta M.、Haba H.、Mori D.、Yokokita T.、Komori Y.、Yamamoto S.、Watanabe Y.
  • Journal Title: Journal of Instrumentation Volume: 16 Pages: P01035～P01035
  • DOI: 10.1088/1748-0221/16/01/P01035
  • Peer Reviewed
• [Journal Article] Radioimmunotherapy with an ²¹¹ At‐labeled anti?tissue factor antibody protected by sodium ascorbate (2021)
  • Author(s): Takashima Hiroki、Koga Yoshikatsu、Manabe Shino、Ohnuki Kazunobu、Tsumura Ryo、Anzai Takahiro、Iwata Nozomi、Wang Yang、Yokokita Takuya、Komori Yukiko、Mori Daiki、Usuda Sachiko、Haba Hiromitsu、Fujii Hirofumi、Matsumura Yasuhiro、Yasunaga Masahiro
  • Journal Title: Cancer Science Volume: 112 Pages: 1975～1986
  • DOI: 10.1111/cas.14857
  • Peer Reviewed
• [Journal Article] Production cross sections of 45Ti in the deuteron-induced reaction on 45Sc up to 24?MeV (2021)
  • Author(s): Tsoodol Zolbadral、Aikawa Masayuki、Ichinkhorloo Dagvadorj、Khishigjargal Tegshjargal、Norov Erdene、Komori Yukiko、Haba Hiromitsu、Tak?cs S?ndor、Ditr?i Ferenc、Sz?cs Zolt?n
  • Journal Title: Applied Radiation and Isotopes Volume: 168 Pages: 109448～109448
  • DOI: 10.1016/j.apradiso.2020.109448
  • Peer Reviewed
• [Journal Article] Measurement of production cross sections of 175Hf in the natLu(p,x) and natLu(d,x) reactions (2021)
  • Author(s): Y. Komori, H. Haba, M. Aikawa, M. Saito, S. Takacs, and F. Ditroi
  • Journal Title: RIKEN Accel. Prog. Rep. Volume: 54 Pages: 171
  • Peer Reviewed
• [Journal Article] Production cross sections of natEr(d,x)171Er reactions on natural erbium (2021)
  • Author(s): M. U. Khandaker and H. Haba
  • Journal Title: RIKEN Accel. Prog. Rep. Volume: 54 Pages: 170
  • Peer Reviewed
• [Journal Article] Production cross sections of 155Tb in deuteron-induced reactions on natural gadolinium (2021)
  • Author(s): D. Ichinkhorloo, M. Aikawa, Ts. Zolbadral, Y. Komori, and H. Haba
  • Journal Title: RIKEN Accel. Prog. Rep. Volume: 54 Pages: 169
  • Peer Reviewed
• [Journal Article] Production cross sections of medical radioisotope 153Sm in alpha-particle-induced reaction on natural neodymium (2021)
  • Author(s): M. Sakaguchi, M. Aikawa, N. Ukon, Y. Komori, H. Haba, N. Otuka, and S. Takacs
  • Journal Title: RIKEN Accel. Prog. Rep. Volume: 54 Pages: 168
  • Peer Reviewed
• [Journal Article] Excitation functions of deuteron-induced reactions on 141Pr for medical radioisotope production (2021)
  • Author(s): M. Aikawa, T. Maehashi, D. Ichinkhorloo, Y. Komori, and H. Haba
  • Journal Title: RIKEN Accel. Prog. Rep. Volume: 54 Pages: 167
  • Peer Reviewed
• [Journal Article] Activation cross section measurement of the deuteron-induced reaction on yttrium-89 for zirconium-89 production (2021)
  • Author(s): M. Sakaguchi, M. Aikawa, M. Saito, N. Ukon, Y. Komori, and H. Haba
  • Journal Title: RIKEN Accel. Prog. Rep. Volume: 54 Pages: 166
  • Peer Reviewed
• [Journal Article] Production cross sections of 68Ga and radioactive by-products in deuteron-induced reactions on natural zinc (2021)
  • Author(s): Ts. Zolbadral, M. Aikawa, D. Ichinkhorloo, Kh. Tegshjargal, N. Javkhlantugs, Y. Komori, and H. Haba
  • Journal Title: RIKEN Accel. Prog. Rep. Volume: 54 Pages: 165
  • Peer Reviewed
• [Journal Article] Cross sections of alpha-particle-induced reactions on natNi: Production of 67Cu (2021)
  • Author(s): S. Takacs, M. Aikawa, H. Haba, Y. Komori, F. Ditroi, Z. Szucs, M. Saito, T. Murata, M. Sakaguchi, and N. Ukon
  • Journal Title: RIKEN Accel. Prog. Rep. Volume: 54 Pages: 164
  • Peer Reviewed
• [Journal Article] Production cross sections of 225Ac in the 232Th(14N,xnyp) reactions at 116 and 132 MeV/nucleon (2021)
  • Author(s): X. Yin, A. Nambu, Y. Komori, D. Mori, S. Oshikiri, H. Kato, A. Hino, and H. Haba
  • Journal Title: RIKEN Accel. Prog. Rep. Volume: 54 Pages: 162-163
  • Peer Reviewed
• [Journal Article] Double photon emission nuclides for double photon coincidence imaging (2021)
  • Author(s): H. Takahashi, M. Uenomachi, K. Shimazoe, and H. Haba
  • Journal Title: RIKEN Accel. Prog. Rep. Volume: 54 Pages: 161
  • Peer Reviewed
• [Journal Article] Development of image reconstruction method for a multiple-isotope PET using 44mSc (2021)
  • Author(s): T. Fukuchi, M. Shigeta, H. Haba, D. Mori, T. Yokokita, Y. Komori, S. Yamamoto, and Y. Watanabe
  • Journal Title: RIKEN Accel. Prog. Rep. Volume: 54 Pages: 160
  • Peer Reviewed
• [Journal Article] Simultaneous imaging of Na+/K+ by semiconductor Compton camera GREI (2021)
  • Author(s): S. Motomura, I. Kii, H. Haba, H. Yakushiji, Y. Watanabe, and S. Enomoto
  • Journal Title: RIKEN Accel. Prog. Rep. Volume: 54 Pages: 159
  • Peer Reviewed
• [Journal Article] Complex formation of Rhenium-186 with lipophilic ligands -Comparison with technetium-99m- (2021)
  • Author(s): I. O. Umeda, H. Haba, Y. Komori, H. Fujii, and T. Takahashi
  • Journal Title: RIKEN Accel. Prog. Rep. Volume: 54 Pages: 157-158
  • Peer Reviewed
• [Journal Article] Quality confirmation of RIKEN 186Re using bifunctional chelating agents and derivatives (2021)
  • Author(s): S. Oshikiri, M. K. Satake, H. Kato, Y. Komori, K. Suzuki, T. Kobayashi, A. Hino, and H. Haba
  • Journal Title: RIKEN Accel. Prog. Rep. Volume: 54 Pages: 156
  • Peer Reviewed
• [Journal Article] Solvent extraction and speciation of astatine species via thin layer chromatography (2021)
  • Author(s): S. Maruyama, K. Aoi, Y. Nagai, K. Washiyama, A. Yokoyama, I. Nishinaka, Y. Wang, and H. Haba
  • Journal Title: RIKEN Accel. Prog. Rep. Volume: 54 Pages: 153
  • Peer Reviewed
• [Journal Article] Solvent extraction of Fr and Cs with calix[4]arene-bis(benzocrown-6) (2021)
  • Author(s): Y. Komori and H. Haba
  • Journal Title: RIKEN Accel. Prog. Rep. Volume: 54 Pages: 152
  • Peer Reviewed
• [Journal Article] Cation- and anion-exchange behavior and UV-vis spectroscopy of Zr in HBr for chemical characterization of bromide complexes of Rf (2021)
  • Author(s): T. Yokokita and H. Haba
  • Journal Title: RIKEN Accel. Prog. Rep. Volume: 54 Pages: 151
  • Peer Reviewed
• [Journal Article] Online anion-exchange experiment of Zr in H2SO4 for the chemical study of Rf in H2SO4 (2021)
  • Author(s): T. Yokokita, Y. Shigekawa, Y. Wang, Y. Komori, Y. Kasamatsu, E. Watanabe, and H. Haba
  • Journal Title: RIKEN Accel. Prog. Rep. Volume: 54 Pages: 149
  • Peer Reviewed
• [Journal Article] Production and photon measurement of 229Pa toward the observation of radiative decay of 229mTh (2021)
  • Author(s): Y. Shigekawa, T. Yokokita, Y. Komori, and H. Haba
  • Journal Title: RIKEN Accel. Prog. Rep. Volume: 54 Pages: 143-144
  • Peer Reviewed
• [Journal Article] Influence of antibody stabilization with sodium ascorbate on radioimmunotherapy with an 211At-conjugated anti-tissue factor antibody (2021)
  • Author(s): H. Takashima, Y. Koga, K. S. Manabe, Onuki, R. Tsumura, T. Anzai, N. Iwata, Y. Wang, T. Yokokita, Y. Komori, D. Mori, H. Haba, H. Fujii, Y. Matsumura, and M. Yasunaga
  • Journal Title: RIKEN Accel. Prog. Rep. Volume: 54 Pages: S32
  • Peer Reviewed
• [Journal Article] 理研におけるAt-211の製造分離状況と将来計画 (2021)
  • Author(s): 羽場宏光
  • Journal Title: 放射線科学フロンティア～孟宗竹～ Volume: 3 Pages: 9
• [Presentation] Compton-PETハイブリッドカメラを用いた診断治療核種同時撮像検証 (2022)
  • Author(s): 上ノ町水紀, 大鐘健一朗, Zhihong Zhong, 島添健次, 鎌田圭, 高橋浩之, Yang Wang, 羽場宏光
  • Organizer: 日本原子力学会2022年春の年会
• [Presentation] 多光子ガンマ線時間・空間相関型イメージング法の研究 1 (全体概要) (2022)
  • Author(s): 高橋浩之, 島添健次, 鎌田圭，羽場宏光，百瀬敏光
  • Organizer: 2022年第69回応用物理学会春季学術講演会
• [Presentation] 多光子ガンマ線時間・空間相関型イメージング法の研究 2 (システム開発) (2022)
  • Author(s): 島添健次, 高橋浩之, 鎌田圭，羽場宏光，上ノ町水紀, 百瀬敏光, 大鐘健一朗
  • Organizer: 2022年第69回応用物理学会春季学術講演会
• [Presentation] 短寿命RIの製造・分離 (2022)
  • Author(s): 羽場宏光
  • Organizer: QiSSシンポジウム
• [Presentation] カルシウム標的へのアルファ粒子入射反応によるSc生成反応断面積測定 (2022)
  • Author(s): 合川正幸, 花田幸奈, ダグワドルジイチンホルロー, 羽場宏光, タカッチサンドール, ディトロイフェレンチ,ズーチゾルタン
  • Organizer: 日本原子力学会2022年春の年会
• [Presentation] アスタチンのハロゲン結合エネルギー測定に向けた条件検討 (2022)
  • Author(s): 床井健運, 豊嶋厚史, 大江一弘, 角永悠一郎, 寺本高啓, 中川創太, 今田彩香, 吉村崇, 笠松良崇, 羽場宏光, 王洋, 篠原厚
  • Organizer: 日本化学会第102春季年会
• [Presentation] 電解酸化反応を利用したアミノ酸へのアスタチン標識法の開発 (2022)
  • Author(s): 中川創太, 角永悠一郎, 大江一弘, 寺本高啓, 床井健運, 神田晃充, 笠松良崇, 永田光知郎, 羽場宏光, 王洋, 吉村崇, 豊嶋厚史, 篠原厚
  • Organizer: 日本化学会第102春季年会
• [Presentation] 新規アルファ線核医学治療薬剤開発を目指した211At-FAPIの合成と評価 (2022)
  • Author(s): 麻生彩佳, 兼田加珠子, 下山敦史, 角永悠一郎, 白神宜史, 渡部直史, 豊嶋厚史, 羽場宏光, 王洋, 篠原厚, 深瀬浩一
  • Organizer: 日本化学会第102春季年会
• [Presentation] Zr及びHfのスルファト錯体推定に向けたTOA/H2SO4系の溶媒抽出 (2022)
  • Author(s): 横北卓也, 羽場宏光
  • Organizer: 日本化学会第102春季年会
• [Presentation] Production and Applications of Radioisotopes at RIKEN RI Beam Factory- Search for New Elements through Diagnosis and Therapy of Cancer- (2021)
  • Author(s): H. Haba
  • Organizer: RIKEN-KFU (Kazan Federal University) 3rd Joint Symposium
  • Int'l Joint Research / Invited
• [Presentation] TATのための228Th/224Ra/212Pbジェネレータシステム開発（2）-高比放射能212Pbの製造- (2021)
  • Author(s): 芝原裕規, 竹村友紀, 福森麻衣, 殷小杰, 南部明弘, 結城真美, 田沢周作, 羽場宏光
  • Organizer: 第61回日本核医学会学術総会
• [Presentation] Rhenium-186の錯体形成に関する諸検討 (2021)
  • Author(s): 梅田泉, 永田みどり, 天﨑茜, 大貫和信, 柳下淳, 桂川美穂, 織田忠, 武田伸一郎, 羽場宏光, 藤井博史, 高橋忠幸
  • Organizer: 第61回日本核医学会学術総会
• [Presentation] Simultaneous PET, SPECT and therapeutic nuclides imaging with Compton-PET hybrid camera (2021)
  • Author(s): Mizuki Uenomachi, Kenichiro Ogane, Zhihong Zhong, Kenji Shimazoe, Kei Kamada, Hiroyuki Takahashi, Yang Wang, and Hiromitsu Haba
  • Organizer: 2021 IEEE Nuclear science symposium and medical imaging conference
  • Int'l Joint Research
• [Presentation] Titanium-44 phantom production and PET imaging for photon activation analysis (2021)
  • Author(s): T. Fukuchi, H. Kikunaga, H. Haba, S. Yamamoto and Y. Watanabe
  • Organizer: 2021 IEEE Nuclear science symposium and medical imaging conference
  • Int'l Joint Research
• [Presentation] Antitumor effect of astatine-211-labeled anti-tissue factor antibody stabilized with sodium ascorbate (2021)
  • Author(s): Hiroki Takashima, Yoshikatsu Koga, Shino Manabe, Kazunobu Ohnuki, Ryo Tsumura, Takahiro Anzai, Yang Wang, Xiaojie Yin, Akihiro Nambu, Nozomi Sato, Sachiko Usuda, Hiromitsu Haba, Hirofumi Fujii, Yasuhiro Matsumura, and Masahiro Yasunaga
  • Organizer: The 80th Annual Meeting of the Japanese Cancer Association
• [Presentation] アスタチン化合物の分光・可視化にむけた新規手法の提案 (2021)
  • Author(s): 寺本高啓，大江一弘，王洋，羽場宏光，豊嶋厚史
  • Organizer: 日本放射化学会第65 回討論会
• [Presentation] 新規アルファ線ブラキセラピー開発に向けたAt-211標識金ナノ粒子の合成と機能評価 (2021)
  • Author(s): 黄栩昊，加藤弘樹，角永悠一郎，下山敦史，樺山一哉，片山大輔，大江一弘，豊嶋厚史，羽場宏光，王洋，篠原厚，深瀬浩一
  • Organizer: 日本放射化学会第65 回討論会
• [Presentation] 電解酸化反応を用いた分子標的薬への211At標識化法の開発 (2021)
  • Author(s): 中川創太，豊嶋厚史，角永悠一郎，大江一弘，寺本高啓，床井健運，神田晃充，吉村崇，永田光知郎，笠松良崇，羽場宏光，王洋，篠原厚
  • Organizer: 日本放射化学会第65 回討論会
• [Presentation] 核医学用アスタチン抽出に利用できるイオン液体の研究 (2021)
  • Author(s): 永井雄太，青井景都，丸山俊平，西中一朗，鷲山幸信，羽場宏光，横山明彦
  • Organizer: 日本放射化学会第65 回討論会
• [Presentation] Atが形成するハロゲン結合の解離エネルギー測定に向けたAtIの生成条件と揮発性の分析 (2021)
  • Author(s): 床井健運，豊嶋厚史，大江一弘，角永悠一郎，寺本高啓，中川創太，吉村崇，笠松良崇，羽場宏光，王洋，篠原厚
  • Organizer: 日本放射化学会第65 回討論会
• [Presentation] 141Pr標的への重陽子入射反応による140Nd生成反応断面積の測定 (2021)
  • Author(s): 合川正幸，前橋拓斗，ダグワドルジ イチンホルロー，江幡修一郎，小森有希子，羽場宏光
  • Organizer: 日本原子力学会2021年秋の大会
• [Presentation] Production of radioisotopes for application studies at RIKEN RI Beam Factory (2021)
  • Author(s): H. Haba
  • Organizer: Snowmass’21 Workshop on High Power Cyclotrons/FFAs
  • Int'l Joint Research / Invited
• [Presentation] Production and applications of radioisotopes at RIKEN RI Beam Factory (2021)
  • Author(s): H. Haba
  • Organizer: International Discussion Meeting on Future of Accelerator Applications and Radiotracers Research (FAAARR2021)
  • Int'l Joint Research / Invited
• [Presentation] 南部明弘, Yin Xiaojie, 羽場宏光, 押切忍, 加藤寛, 日野明弘 (2021)
  • Author(s): 232Th＋14N反応による225Acの製造
  • Organizer: 第58回アイソトープ・放射線研究発表会
• [Presentation] 理研RIビームファクトリーにおけるRI製造供給 (2021)
  • Author(s): 羽場宏光
  • Organizer: 第58回アイソトープ・放射線研究発表会
• [Presentation] アルファ線放出核種アスタチン-211結合抗組織因子抗体の前臨床試験 (2021)
  • Author(s): 髙島大輝, 眞鍋史乃, 大貫和信, 古賀宣勝, 津村遼, 安西高廣, Wang Yang, Yin Xiaojie, 南部明弘, 佐藤望, 臼田祥子, 羽場宏光, 藤井博史, 松村保広, 安永正浩
  • Organizer: 第37回日本DDS学会学術集会
• [Presentation] 複数トレーサーPETを用いた異なるがん診断薬の直接比較 (2021)
  • Author(s): 福地知則, 金山洋介, 蔵地理代, 中谷友香, 羽場宏光, 森大輝, 横北卓也, 小森有希子, 山本誠一, 渡辺恭良
  • Organizer: 第15回日本分子イメージング学会総会・学術集会