2019 Fiscal Year Final Research Report
Investigation of the rectivity of highly-strained sp-carbon atom in organometallic five-membered unsaturated molecules and its application
| Project/Area Number |
17K05791
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Organic chemistry
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| Research Institution | Sophia University |
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Principal Investigator |
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| Project Period (FY) |
2017-04-01 – 2020-03-31
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| Keywords | 高歪み環状不飽和炭化水素 / ジルコニウム / 五員環アレン / アミド |
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| Outline of Final Research Achievements |
We recently developed novel organozirconium compounds that are have a five-membered cyclic allene structure. These compounds are surprisingly stable despite their highly strained structure, and were prepared from low-valent zirconium complexes and 1,3-enyne compounds. In this study, we investigated their property and reactivity on carbene-like character of center-carbon of the allene moiety. Nucleophilic addition of the unsaturated hydrocarbyl part to isocyanate esters, for example, afforded amide of allene moieties.
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| Free Research Field |
有機金属化学
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| Academic Significance and Societal Importance of the Research Achievements |
安定な五員環アレン化合物は2008年に代表者らが初めて報告したが、それまで五員環アレンは不安定で単離できないというのが有機化学の常識であった。それゆえこの化合物の性質、反応性についてはいまだに多く知られていない。この特異な構造を有する化合物についてつまびらかにすることは今後の構造有機化学的な理解の上で学術的な意義が大きい。さらにこれらの分子を種々の有機合成反応へ利用できる例を示したことにより、官能基を有する不飽和炭化水素の新たな合成方法を見出した点において社会的意義を有する
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