Elucidation of the effects of cognitive rehabilitation for schizophrenia on neural activity in the brain

2022 Fiscal Year Final Research Report

• Project/Area Number: 17K17556
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Rehabilitation science/Welfare engineering; Applied health science
• Research Institution: Osaka Kawasaki Rehabilitation University (2020-2022); Hokkaido University (2017-2019)
• Principal Investigator: INOUE Takao 大阪河崎リハビリテーション大学, リハビリテーション学部, 講師 (40779427)
• Project Period (FY): 2017-04-01 – 2023-03-31
• Keywords: 認知機能 / 神経可塑性 / 事象関連電位 / 統合失調症

Outline of Final Research Achievements

From the results obtained, cognitive rehabilitation intervention by NEAR improves performance in behavioral tests such as neuropsychological tests, but ERP such as P300 during attention tasks and late positive components during memorization tasks, and time-frequency analysis It was clarified that the change in the power value of neural activity in each band caused by the effect did not change the neural activity of the brain at a level at which the effect could be grasped.

Free Research Field

cognitive neuroscience

Academic Significance and Societal Importance of the Research Achievements

得られた結果より、NEARによる認知リハ介入では神経心理学検査などの行動学検査では成績が向上するが、注意課題時のP300や記銘課題時の後期陽性成分などのERP、また時間周波数解析による各帯域の神経活動のパワー値の変化では効果を把握できるレベルでは脳の神経活動には変化が生じないということが明らかになった。研究成果は国際学会で報告し、投稿した論文は現在査読中である。