Role of embryonic muscle as hematopoietic niche

2018 Fiscal Year Final Research Report

• Project/Area Number: 17K19530
• Research Category: Grant-in-Aid for Challenging Research (Exploratory)
• Allocation Type: Multi-year Fund
• Research Field: Biomedical structure and function and related fields
• Research Institution: Kyushu University
• Principal Investigator: Sugiyama Daisuke 九州大学, 先端融合医療創成センター, 教授 (00426652)
• Project Period (FY): 2017-06-30 – 2019-03-31
• Keywords: 造血ニッチ

Outline of Final Research Achievements

Hematopoietic stem and progenitor cells (HPSCs) are regulated and maintained by microenvironment and are thought to expand in fetal liver and spleen, and then move to bone marrow before birth. On the other hand, we found that c-kit+ HSPCs exist in muscle tissue (Tanaka et al., PLoS One, 2015).
Hereinafter, it will not be disclosed for a certain period of time due to patent applications.

Free Research Field

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Academic Significance and Societal Importance of the Research Achievements

特許出願の関係上一定期間非公開とする。